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All Journal JURNAL PETERNAKAN Jurnal Zarah Jurnal Kesehatan Medika Saintika JURNAL ILMIAH PETERNAKAN TERPADU Majalah Kedokteran Andalas Jurnal Abdi Insani SPEKTA (Jurnal Pengabdian Kepada Masyarakat : Teknologi dan Aplikasi) Bioscientist : Jurnal Ilmiah Biologi Jurnal Kesehatan Saintika Meditory Jurnal Peternakan Borneo Jurnal Medisains Kesehatan Science, Technology, and Communication Journal
Heppy Setya Prima
Stikes Syedza Saintika
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Journal : Jurnal Zarah

 1 
UJI AKTIVITAS ANTIBAKTERI EKSTRAK KULIT JERUK JESIGO  (Citrus nobilis Lour) TERHADAP BAKTERI Escherichia coli DAN Listeria monocytogenes Setya Prima, Heppy; Yansen, Fatridha
Jurnal Zarah Vol. 12 No. 1 (2024): Jurnal Zarah
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Maritim Raja Ali Haji

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Listeria monocytogenes dan Escherichia  coli adalah bakteri penyebab berbagai infeksi pada manusia. Kulit jeruk JESIGO  (Citrus nobilis Lour) mengandung  senyawa kimia berupa flavonoid,  alkaloid,  saponin  dan  tanin yang  berfungsi  sebagai  antibakteri. Penelitian  ini  bertujuan  untuk  mengetahui  aktivitas ekstrak kulit jeruk JESIGO  (Citrus nobilis Lour) dalam menghambat pertumbuhan bakteri Escherichia coli dan  Listeria monocytogenes.  Penelitian ini merupakan eksperimental laboratorium  dengan metode  difusi  agar untuk mengetahui daya hambat terhadap bakteri Escherichia coli dan  Listeria monocytogenes melalui pembentukan zona inhibisi. Sampel  yang  digunakan adalah bakteri Escherichia coli dan  Listeria monocytogenes. Beberapa variasi konsentrasi ekstrak kulit jeruk JESIGO; 5%, 15%, 25%,  45%, digunakan dalam penelitian ini.  Amoxicilin  dan DMSO digunakan sebagai kontrol positif dan kontrol negatif. Berdasarkan hasil penelitian,  konsentrasi ekstrak kulit jeruk JESIGO konsentrasi 45% menunjukkan daya hambat terbaik terhadap E. coli O157 dengan diameter zona hambat sebesar 15,76 mm (kuat). Diameter zona hambat terbesar terhadap bakteri Listeria monocytogenes diperoleh dari ekstrak kulit jeruk JESIGO dengan kosentrasi 45% yaitu 19,98 mm (kuat). Hasil penelitian menunjukkan bahwa ekstrak kulit jeruk JESIGO  (Citrus nobilis Lour)  memiliki aktivitas antibakteri terhadap Escherichia coli dan  Listeria monocytogenes dalam kategori kuat.
PERBANDINGAN AKTIVITAS ANTI-HIPERURISEMIA EKSTRAK ETANOL SELEDRI (APIUM GRAVEOLENS L.) DAN DAUN SALAM (SYZYGIUM POLYANTHUM) PADA MENCIT YANG DIINDUKSI KAFEIN Yansen, Fatridha; Nanda Putra; Yesi Gusnelti; Heppy Setya Prima
Jurnal Zarah Vol. 13 No. 1 (2025): Jurnal Zarah
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Maritim Raja Ali Haji

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Celery plants (Apium Graveolens L) and bay leaves (Syzygium polyanthum) have been used as alternative medicine to treat Hyperuricemia. This study aimed to determine the effectiveness of administration of extracts from celery plants and bay leafs to decrease uric acid levels in blood. This research used a post-test control group only design. A total of 24 male mice (randomly divided into 4 groups; P0, P1, P2 and P3). P0 was the control group (induced with caffeine at a dose of 0.5 mg/kgBW). P1 was induced with caffeine 0.5 mg/kgBW+celery extract 35 mg/kgBW, P2 was induced by caffeine 0.5 mg/kgBW+bay leaf extract 35 mg/kgBW and P3 was induced by caffeine + a combination of celery plant extract and bay leaves 35mg/kgBW. Uric acid levels were measured using an easy touch GCU meter device. The results showed that average of uric acid level for P0, P1, P2 and P4 were 7.1mg/dl; 4.9 mg/dl; 4 mg/dl; and 5.2 mg/dl, respectively. The most significant antihyperuricemia activity was demonstrated by administering 35 mg/kgBW of bay leaf extract. The One Way ANOVA analysis described that the administration of extract ethanol generated significant effects (p-value <0.05). Based on post hoc LSD analysis, it was found that the administration of ethanol extract from bay leaves showed significant differences compared to combination (celery + bay leaves) in lowering uric acid levels. Therefore, it was concluded extract from celery and bay leaves can be used to lower the level of uric acid
Co-Authors Abdul Muin Sibuea Adelia Febriyossa Agasi, Satri Yusasra Annita, Annita Diningrat, Diky Setya Eldya Mossfika Fadhli Fajri fajri maulana fajri, fadhli fadhli Fatridha Yansen Febrina, Bunga Putri Harahap, Novita Sari Ibrahim Ibrahim inelvi yulia Jamaludin, Askiah Binti laela Sari, laela Maulana, Bagoes Muhammad Amran Nanda Putra Nasution, Alvi Sahrin Noviyanti, Aidha Pardosi, Sri Masnita Pricilia, Adelva Raden Mohamad Herdian Bhakti Retno Dwi Suyanti Ruqaya annisa nurul haq Sandri, Dwi Susalam, Malikil Kudus Yansen, Fatridha Yesi Gusnelti Yetti Marlida Yulia Beti yulia, inelvi Zahra, Eliza