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All Journal Farmaka Jurnal Tumbuhan Obat Indonesia Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Buana Farma Jurnal Ilmiah Kesehatan Masyarakat Jurnal Farmasi Klinik dan Sains Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Jurnal Pengabdian Masyarakat Bangsa Detector: Jurnal Inovasi Riset Ilmu Kesehatan Journal of Pharmaceutical and Sciences. JPS (Jurnal Pharma Saintika) Ardhi: Jurnal Pengabdian dalam Negri Journal of Clinical Pharmacy and Pharmaceutical Science KREATIF: Jurnal Pengabdian Masyarakat Nusantara
Ghalib Syukrillah Syahputra
Institut Kesehatan Mitra Bunda, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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AKTIVITAS ANTIOKSIDAN DARI EKSTRAK BUAH CANTIGI UNGU (Vaccinium varingiaefolium (Bl.) Miq.) GHALIB SYUKRILLAH SYAHPUTRA; Yoppi Iskandar; Aliya Nur Hasanah
Farmaka Vol 14, No 4 (2016): Farmaka
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (626.144 KB) | DOI: 10.24198/jf.v14i4.10511

Abstract

Saat ini Bilberry telah dikenal dikalangan optamologis sebagai tumbuhan obat yang dapat berperan dalam kesehatan mata. Di sekitar kawah pegunungan Patuha (Bandung selatan) dapat dijumpai tumbuhan yang cukup mendominasi vegetasi di daerah tersebut yaitu tumbuhan cantigi ungu (Vaccinium varingiaefolium (Bl.) Miq.). Melalui pendekatan kemotaksonomi maka cantigi ungu dapat berpotensi sebagai obat untuk memelihara kesehatan mata. Diet antioksidan merupakan tindakan preventif dalam menanggulangi gangguan kesehatan, salah satunya seperti yang telah dilaporkan bahwa diet antioksidan dapat membantu memelihara kesehatan penglihatan khususnya dapat berpotensi mengobati katarak (Carey et al., 2011; Varma et al., 2012). Tujuan penelitian ini yaitu mengetahui khasiat antioksidan yang dimiliki tumbuhan cantigi ungu. Tahapan metode yang dilakukan yaitu pengumpulan bahan, ekstraksi, pengukuran kadar flavonoid total dan pengujian aktivitas antioksidan ekstrak buah cantigi ungu menggunakan metode DPPH (2,2-difenil-1-pikrilhidrazil). Dari hasil penelitian kadar flavonoid total ekstrak cantigi ungu yaitu 37.6 ppm ekuivalen kuersetin. Untuk pengujian kemampuan antioksidan cantigi ungu lebih rendah dibanding vitamin C dan tablet ekstrak bilberry dari data IC50 yang didapat yaitu IC50 vitamin C 5.710 ppm; IC50 Ekstrak cantigi ungu 242.924 ppm; IC50 Tablet Ekstrak bilberry 44.994 ppm.Kata kunci : Vaccinium, Cantigi ungu, Bilberry, Antioksidan
KAJIAN ETNOFARMASI DAN FITOKIMIA TUMBUHAN OBAT KAMPUNG ADAT URUG, KECAMATAN SUKAJAYA, KABUPATEN BOGOR, JAWA BARAT Ghalib Syukrilah Syahputra; Mutiara Ayudia Astuti; Piter Piter; Dayar Arbain
Jurnal Tumbuhan Obat Indonesia Vol 14 No 1 (2021): Jurnal Tumbuhan Obat Indonesia
Publisher : Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jtoi.v14i1.3016

Abstract

ABSTRACT Knowledge and arts of the traditionally use of medicinal plant are valuable assets of Indonesian culture, which should be documented and preserved. Simultaneously, the plant that are traditionally used for health care should be investigated, particularly regarding their chemical constituents, biological activities and their safety, as well. This study aimed to inventory of medicinal plants used by people from Kampung Adat Urug, a Sundanese traditional village. This community still practices their traditional way of life, including how to maintain health and to treat illness. This study began with an ethnobotanical survey using Participation Observatory Method (POM) and interviewing the selected traditional healers. Data analysis was carried out by calculating Use Value (UV), Relative Frequency of Citation (RFC), and Relative Importance (RI) of plant species. The study revealed 29 medicinal plants used by Kampung Urug community. Five medicinal plants (Ixora salicifolia, Scleria levis, Hippobroma longiflora; Pterocarpus indicus and Pothos junghuhnii) showed high level of UV, RFC, and RI. Those species were found to be potential in treating various neglected diseases, women health care during pregnancy, postpartum illness, and maintaining health care in general. Besides, there were four plants extracts, each from Barringtonia acutangula; Pterocarpus indicus; Selaginella cf. lana and Pothos junghuhnii which showed potent inhibition against Staphylococcus aureus. The phytochemical screening of the above extracts showed various major constituents, particularly phenolics and flavonoids. Keywords: Ethnopharmacy, Kampung Urug, Phytochemistry ABSTRAK Pengetahuan dan seni tentang penggunaan tumbuhan obat merupakan salah satu kekayaan budaya bangsa Indonesia yang harus didokumentasikan dan dilestarikan. Secara bersamaan tumbuhan obat yang digunakan untuk pemeliharaan kesehatan dan obat itu juga harus diteliti, khususnya kandungan kimia dan bioaktifitasnya serta divalidasi khasiat dan keamanan penggunaannya. Adapun tujuan dari penelitian ini adalah untuk menginventarisasi penggunaan tumbuhan obat oleh salah satu masyarakat adat Suku Sunda yang tinggal tidak jauh dari kota Bogor yang dikenal dengan nama Kampung Adat Urug. Mereka hidup secara tradisional termasuk bagaimana memelihara kesehatan dan mengobati penyakit. Kajian ini dimulai dengan melakukan survei etnobotani menggunakan metode Participation Observatory Method (POM) dan mewawancarai beberapa dukun terpilih menggunakan analisis Use Value (UV), Relative Frequency of Citation (RFC), dan Relative Importance (RI). Pada kegiatan ini telah terkumpul 29 jenis tumbuhan obat, dibuat spesimen herbariumnya dan disiapkan juga ekstrak metanol dari tumbuhan obat yang dikoleksi tersebut. Berdasarkan metode POM dan wawancara beberapa dukun terpilih menggunakan analisis UV, RFC, dan RI, terpilih lima jenis tumbuhan obat, yaitu: Ixora salicifolia, Scleria levis, Hippobroma longiflora, Pterocarpus indicus dan Pothos junghuhnii, yang potential digunakan untuk berbagai penyakit terabaikan, perawatan wanita hamil dan setelah melahirkan serta untuk pemeliharaan kesehatan secara umum. Berdasarkan studi pustaka terdapat empat ekstrak tumbuhan; Barringtonia acutangula, P. indicus, Selaginella cf. plana, dan P. junghuhnii yang menghambat kuat pertumbuhan bakteri Staphylococcus aureus yang sering menyebabkan infeksi secara umum. Hasil penapisan fitokimia terlihat bahwa ekstrak-ekstrak yang aktif antimikroba di atas memperlihatkan adanya kandungan senyawa kimia khususnya senyawa fenolik dan flavonoid yang diperlukan untuk perencanaan kajian-kajian isolasi dan karakterisasi kandungan senyawa aktif yang ada. Kata kunci: Etnofarmasi, Fitokimia, Kampung Urug
Penetapan Kadar Total Flavonoid dan Tanin Ekstrak Daun Bidara Arab (Ziziphus Spina-christi Lam) Shinta Cania Maiza; Trie Yuni Elfasyari; Ghalib Syukrillah Syahputra
Journal Pharma Saintika Vol. 5 No. 2 (2022): April : Jurnal Pharma Saintika
Publisher : Program Studi DIII Farmasi Akademi Farmasi Dwi Farma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51225/jps.v5i2.13

Abstract

Arabic Bidara Leaf (Ziziphus Spina-christi Lam) is one of the plants used as herbal medicine. Traditionally, the Arabic Bidara plant can be used as a medicine for wounds, eye diseases, and skin diseases. Previous research stated that the Bidara Arab plant contains secondary metabolites such as flavonoids, tannins, sterols, saponins and triterpenoids. This study aims to determine the total levels of flavonoids and tannins contained in the water extract of Bidara Arab leaves. The extraction method used in this research is the maceration method. In the study of determining the total flavonoid and tannin levels using UV-Vis Spectrophotometry, the wavelength used to determine the total flavonoid content was 441 nm and for the total tannin content was 740 nm. The standard used in this study was quercetin for total flavonoid content and gallic acid for total tannin content, made with several variations in concentration. The results showed that the total flavonoid content was 0.0869% and the total tannin content was 0.2864%..
Pengabdian Kepada Masyarakat Melalui Penyuluhan Pemberian Makan Yang Tepat Pada Bayi Dan Dalam Upaya Pencegahan Stunting Di Bengkong Sadai Kota Batam Suhaera Suhaera; Aprilya Sri Rachmayanti; Yunisa Friscia Yusri; Ghalib Syukrillah Syahputra
ARDHI : Jurnal Pengabdian Dalam Negri Vol. 1 No. 1 (2023): ARDHI : Jurnal Pengabdian Dalam Negri
Publisher : Asosiasi Riset Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ardhi.v1i1.217

Abstract

The prevalence of stunting is one of the biggest nutritional problems among toddlers in Indonesia. The proportion of short and very short nutritional status in babies under two years old (baduta) reached 29.9% or higher than the 2019 RPJMN target, which was 28%. Stunting due to malnutrition that occurs in the First 1000 Days of Life (HPK) notonly causes obstacles to physical growth and increases vulnerability to disease, but also threatens cognitive development which will affect children's intelligence and productivity levels.Objective: To know the nutritional status of children under five, especially related to stunting, to increase parents' knowledge about stunting, to raise public awareness of the dangers of stunting.The activities consist of preparation stages, implementation of counseling which begins with filling in the pre-test questionnaire and ends with filling in the post-test questionnaire, as well as the evaluation stage.
Pengabdian Kepada Masyarakat Melalui Peningkatan Kualitas Hidup Lansia Melalui Penerapan Pola Hidup Sehat Di Batam Aprilya Sri Rachmayanti; Suhaera Suhaera; Ghalib Syukrillah Syahputra; Henny Rachdiati
ARDHI : Jurnal Pengabdian Dalam Negri Vol. 1 No. 1 (2023): ARDHI : Jurnal Pengabdian Dalam Negri
Publisher : Asosiasi Riset Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/ardhi.v1i1.220

Abstract

The aging process is a natural phenomenon experienced by every individual, characterized by physical and mental changes that affect the body's functions and capabilities. The speed of the aging process can vary between individuals due to the influence of hormones and other factors. Elderly is often thought of as a disease, whereas aging is actually a natural process of decreasing the body's resistance to external and internal stimuli. During aging, the elderly experience physical, mental and psychological changes. Efforts to improve the health of older adults with chronic diseases are made through the adoption of a healthy lifestyle. This includes regular exercise programs, a healthy diet by limiting salt, fat, and cholesterol intake, quitting smoking, avoiding alcoholic beverages and caffeine, managing emotional stress, and undergoing regular monthly health check-ups. With age, older adults are at risk of various diseases, decreased body functions, imbalances, and the risk of falls. These challenges often conflict with older adults' desire to remain independent and active. The mismatch between expectations and conditions can even lead to depression. Therefore, there is a need for special attention to the health and well-being of the elderly with chronic diseases to maintain their quality of life.
Analisis Kandungan Asam Retinoat Pada Krim Anti Jerawat Di Toko Kosmetik X Pasar Jodoh Diani Mega Sari; Eka Febriyanti; Ghalib Syukrillah Syahputra; Annisa Laili Oktaviyani
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 3 No. 1 (2024): Januari 2024
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v3i1.3002

Abstract

Growth from adolescence to adulthood is a transition that causes many hormonal changes, both physical, psychological and social. This change will cause health problems, one of which is on the face, namely Acne vulgaris (AV). Retinoic acid is one of the chemicals that is prohibited for use because it can cause dry skin, burning, teratogenicity (fetal defects)0and skin cancer. The aim of this research was to find out whether the acne cream in the cosmetic shop x Pasar Jodoh contained retinoic acid, and to determine the levels of retinoic acid in the samples. There were 10 acne cream samples studied. The qualitative test of retinoic acid uses the thin layer chromatography (TLC) method observed under UV 254 light. And the quantitative test uses the UV-Vis Spectrophotometry method. Spectrophotometric determination of retinoic acid levels at a wavelength of 340 nm. The results0obtained by the thin layer chromatography (TLC) method were that sample B was positive for retinoic acid and the results from the UV-Vis spectrophotometry0method were 0.0005%.
Penetapan Kadar Fenolik Total Ekstrak Daun Jotang (Sphagneticola Trilobata) Dengan Spektrofotometri UV-Vis Ghalib Syukrillah Syahputra; Delladari Mayefis; Tommy Julianto; Lyna Elvira
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 2 No. 1 (2023): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v2i1.2669

Abstract

Phenolic compounds are the largest group of compounds that act as natural antioxidants in plants. One of the plants that has the potential as a natural antioxidant is Jotang (Sphagneticola trilobata). This study aims to determine whether jotang leaf extract (Sphagneticola trilobata) has phenolic content and to determine the total phenolic content in jotang leaf extract (Sphagneticola trilobata). Jotang leaves were extracted by maceration method using methanol solvent. The method of determining total phenolic content was carried out using Folin-ciocaltaeu reagent because phenolic compounds can react with Folin-Ciocalteu to form a solution that can be measured absorbance. As a standard solution, gallic acid is used which is reacted with Folin-Ciocalteau reagent to produce a yellow color indicating that it contains phenolics, after which it is added with Na₂CO₃ solution as a base atmosphere giver. The phytochemical screening of jotang leaf extract showed positive results containing flavonoids, alkaloids, saponins, phenolic compounds, and triterpenoids. Determination of the wavelength of gallic acid obtained maximum 653 nm. The results showed that jotang leaf extract (Sphagneticola trilobata) has phenolic content and obtained total phenolic content of jotang leaf extract of 0.909 mg /g.
Uji Aktivitas Antibakteri Fraksi Ekstrak Daun Jotang (Sphagneticola trilobata L) terhadap Bakteri Eschericia coli Ghalib Syukrillah Syahputra; Ibnu Rusyd; Arie Vonikartika; Zahara Zahara; Eka Febriyanti; Delladari Mayefis
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 4 No. 1 (2025): Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v4i1.58

Abstract

Jotang (Sphagneticola trilobata) is a wild plant that has antibacterial potential. This study aims to determine the antibacterial activity of the n-hexane, ethyl acetate and methanol fractions of jotang leaf extract against Escherichia coli bacteria. Jotang leaves were extracted using methanol by maceration extraction method, followed by the fractionation stage using Liquid-Liquid Extraction method. The fractionation process uses n-hexane, ethyl acetate and methanol as solvents. Next step, each fraction was tested for antibacterial activity using the disc diffusion method. The concentrations of each fraction used were 200 µg/disc, 400 µg/disc, and 1000 µg/disc, positive control used chloramphenicol and negative control used DMSO 10%. The Result showed the most potential antibacterial activity of the active fraction from jotang leaves extract was the n-hexane fraction.
Hubungan Status Gizi dan Kekambuhan Tuberkulosis di Balai Besar Kesehatan Paru Masyarakat Surakarta Febriyanti , Eka; Amelia, Ayu; Meilanda , Rastria; Syahputra , Ghalib Syukrillah
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.792

Abstract

Malnutrition can weaken the immune system, thereby increasing the risk of Mycobacterium tuberculosis infection. The aim of this study was to determine the risk of tuberculosis (TB) recurrence associated with the nutritional status of TB patients. This study was conducted at the Surakarta Center for Lung Health in 2017 using a case-control design. The study included 15 individuals in the control group (patients who had been cured of TB) and 15 individuals in the case group (patients who experienced TB recurrence). Inclusion criteria for this study were TB patients aged 18-65 years, both male and female, who had completed the full course of TB treatment, and who had complete data on nutritional status measured through Body Mass Index (BMI) and documented dietary intake in medical records. Patients with metabolic disorders or chronic diseases other than TB that could influence nutritional status were excluded. Data were collected from medical records and analyzed using SPSS version 25. The results showed that patients with poor nutritional status (below the normal BMI) had a significantly higher risk of TB recurrence (p = 0.028). Another finding indicated that patients who had a habit of consuming alcohol also had a higher likelihood of TB recurrence (p = 0.001). The conclusion of this study is that poor nutritional status plays a role in the occurrence of recurrent tuberculosis.
UJI ANTIBAKTERI EKSTRAK BATANG GAHARU (Aquilaria malaccensis) BERBASIS KOLIN KLORIDA:ASAM SITRAT TERHADAP Bacillus cereus dan Shigella dysenteriae Hasan, Nahrul; Marlina, Sri; Amelia, Ayu; Syahputra, Ghalib Syukrillah; Sari, Diani Mega
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1396

Abstract

Infections caused by Bacillus cereus and Shigella dysenteriae are serious health problems as they can lead to gastrointestinal disorders and contribute to the emergence of antibiotic resistance. One potential strategy to overcome this challenge is the discovery of new antibacterial agents derived from natural sources, such as agarwood (Aquilaria malaccensis). This study aimed to evaluate the antibacterial activity of gaharu stem extract using a Natural Deep Eutectic Solvent (NADES) composed of choline chloride and citric acid through the Ultrasound Assisted Extraction (UAE) method. The antibacterial assay was performed using the disc diffusion method with various NADES ratios (1:1, 2:1, 1:2, 1:3, 1:4, and 4:1 g/g), with chloramphenicol as the positive control and 10% DMSO as the negative control. The results indicated that the NADES extract with a 1:4 g/g ratio produced the largest inhibition zones against Bacillus cereus and Shigella dysenteriae. Moreover, the Minimum Inhibitory Concentration (MIC) test showed that the 1:4 NADES extract effectively inhibited bacterial growth at a concentration of 30%. These findings suggest that gaharu stem extract prepared with NADES is a promising, eco-friendly, and potent antibacterial agent.
Co-Authors Aliya Nur Hasanah Amelia, Ayu Annisa Laili Oktaviyani Aprilya Sri Rachmayanti Arie Vonikartika Ayu Amelia DAYAR ARBAIN Delladari Mayefis Delladari Mayefis Desy Gusmali Maniarti Desy Maniarti Gusmali Desy Maniarty Gusmali Dhia Suhailah Diani Mega Sari Didi Yunaspi Eka Febriyanti Eka Febriyanti Elfasyari, Trie Yuni Faizah Zalsabila Ghiffari, Habibie Deswilyaz Hasan, Nahrul Henny Rachdianti Tjahjono Suyarto Henny Rachdiati I Gusti Ngurah Agung Artawijaya Ibnu Rusyd Julianto, Tommy Lyna Elvira Meilanda , Rastria Meilanda, Rastria Mutiara Ayudia Astuti Nahrul Hasan Nela Yulia Putri Nurwijayanti Piter Piter Rachel Bintang Rivelino William Putra Nazara Roza Erda Rury Trisa Utami Shinta Cania Maiza Shinta Sari Dewi Sri Budiasih Sri Budiasih Sri Hainil Sri Marlina, Sri Suci Fitriani Sammulia Suhaera Suhaera Suhaera Suhaera Yoppi Iskandar Yunisa Friscia Yusri Zahara Zahara