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All Journal Farmaka Jurnal Tumbuhan Obat Indonesia Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Buana Farma Jurnal Ilmiah Kesehatan Masyarakat Jurnal Farmasi Klinik dan Sains Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Jurnal Pengabdian Masyarakat Bangsa Detector: Jurnal Inovasi Riset Ilmu Kesehatan Journal of Pharmaceutical and Sciences. JPS (Jurnal Pharma Saintika) Ardhi: Jurnal Pengabdian dalam Negri Journal of Clinical Pharmacy and Pharmaceutical Science KREATIF: Jurnal Pengabdian Masyarakat Nusantara
Ghalib Syukrillah Syahputra
Institut Kesehatan Mitra Bunda, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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KENDALA RETENSI TERAPI ANTIRETROVIRAL (ARV) PADA PASIEN HIV/AIDS DI RSUD DR MOEWARDI (RSDM) SURAKARTA JAWA TENGAH Febriyanti, Eka; Sari, Diani Mega; Syahputra, Ghalib Syukrillah; Hasan, Nahrul; Amelia, Ayu; Meilanda, Rastria
Jurnal Farmasi Klinik dan Sains Vol 4, No 1 (2024): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v4i1.1365

Abstract

Terapi Antiretroviral (ARV) bertujuan untuk mengurangi risiko penularan HIV/AIDS, menghambat perburukan infeksi oportunistik, meningkatkan kualitas hidup Orang DenganHIV/AIDS (ODHA) dengan menurunkan jumlah viral load dan meningkatkan jumlah CD4. Kunci keberhasilan terapi ARV adalah mempertahankan retensi. Lost To Follow Up (LTFU) dan kegagalan pengobatan menjadi kendala bagi ODHA dalam mencapai keberhasilan pengobatan ARV. Penelitian ini bertujuan untuk mengetahui prediktor hambatan mendapatkan retensi pengobatan ARV. Penelitian ini menggunakan rancangan case control dengan jumlah sampel 100 responden. Analisis data dilakukan dengan menggunakan metode chi-square. Hasil analisis bivariat, prediktor buruknya retensi berdasarkan persepsi pasien terhadap hambatan menjalani terapi ARV adalah kendala biaya transportasi (p=0.002; COR=8.34), kendala jarak perjalanan ke RSDM (p=0.002; COR=5.06), hambatan kesibukan lainnya (p=<0.001; COR=6,64), memiliki Pengawas Menelan Obat (p=0.003; COR=6.64), mengungkapkan status ODHA kepada orang lain (p=0.004; COR= 12.25), dan stigma (p=<0.001; COR= 12,3). Berdasarkan hasil uji multivariat persepsi pasien terhadap hambatan dalam menjalankan terapi ARV yang paling berdampak pada buruknya retensi terapi adalah mengungkapkan status ODHA kepada orang lain (AOR=13.1; p=0.042).
Pengabdian Kepada Masyarakat Melalui Ekonomi Kreatif Wedang Jahe Srr...Bukhe Bulang Lintang RT.02 Kota Batam Delladari Mayefis; Suci Fitriani Sammulia; Ghalib Syukrillah Syahputra; Desy Maniarti Gusmali
KREATIF: Jurnal Pengabdian Masyarakat Nusantara Vol. 1 No. 3 (2021): September : Jurnal Pengabdian Masyarakat Nusantara
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/kreatif.v1i3.2958

Abstract

Ginger drink is a traditional beverage made from red ginger (Zhingiber officinale Rosc.var.rubrum), which is commonly used as a spice, a warming agent, and a raw material for traditional medicine. Ginger drink is a product that faces increasing competition, especially with the growing number of instant ginger drink brands on the market. The types of data used in the research are primary data and secondary data. The analysis method is carried out in accordance with the provisions of PPOMN in 2006. Ginger drink can also be used as an immune-boosting beverage, as demonstrated in virtual training sessions on making homemade ginger drinks to educate people about the importance of maintaining a healthy immune system. Ginger drink has the potential to reduce the risk of diseases like type 2 diabetes, as it contains gingerol and shogaol, which can inhibit fat synthesis and improve insulin sensitivity. The utilization of ginger in the production of instant powdered ginger drinks and ginger milk drinks in micro and small businesses (UMKM) has also been carried out. This production involves cooking, filtering out ginger residue, adding palm sugar and granulated sugar, and packaging.
Pengabdian Kepada Masyarakat Melalui Penyuluhan Perilaku Hidup Sehat Kota Batam Suhaera Suhaera; Ghalib Syukrillah Syahputra; Aprilya Sri Rachmayanti; Henny Rachdianti Tjahjono Suyarto
KREATIF: Jurnal Pengabdian Masyarakat Nusantara Vol. 1 No. 3 (2021): September : Jurnal Pengabdian Masyarakat Nusantara
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/kreatif.v1i3.2960

Abstract

Batam City faces health problems related to lifestyle, such as obesity, diabetes, hypertension and heart disease. This can be caused by unhealthy eating patterns, lack of physical activity, as well as smoking and alcohol consumption. Counseling about the importance of a healthy lifestyle is important to reduce morbidity and mortality due to this disease. Healthy Living Behavior Counseling in Batam City not only aims to increase people's knowledge about healthy eating patterns and the importance of exercise, but also to change their attitudes and behavior in daily practice. Through outreach that is held systematically and continuously, it is hoped that the people of Batam City can understand the positive impact they will experience by adopting a healthy lifestyle.
Uji Aktivitas Antiinflamasi Fraksi N-Heksana dan Fraksi Etil Asetat Daun Kemiri (Aleurites moluccanus)Terhadap Mencit Putih Jantan (Mus musculus) Nela Yulia Putri; Ghalib Syukrillah Syahputra; Dhia Suhailah
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 3 No. 4 (2025): Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v3i4.5735

Abstract

Inflammation is a common condition that affects everyone and can affect quality of life. Candlenut leaves (Aleurites moluccanus) are known to contain flavonoid compounds, such as swertisin and 2''-O-rhamnosylswertisin, which are thought to have anti-inflammatory activity. This study aims to test the anti-inflammatory activity of candlenut leaves using four treatment groups, namely positive control (sodium diclofenac), negative control (Na-CMC), n-hexane fraction (200 mg/KgBW), and ethyl acetate fraction (200 mg/KgBW). Leg edema volume measurements were carried out periodically for up to 6 hours using a digital caliper. The results showed that the percentage of edema inhibition in the negative control group reached 64.13%, positive control 38.91%, n-hexane fraction 39.99%, and ethyl acetate fraction 39.82%. Although the ethyl acetate fraction showed better anti-inflammatory activity than the n-hexane fraction, its inhibition percentage was still lower than that of the positive control. These findings suggest that candlenut leaves have potential as a source of anti-inflammatory compounds, particularly the ethyl acetate fraction. Further research is needed to evaluate its efficacy and mechanism of action.
Isolasi Senyawa Utama Daun Setebal (Glochidion superbum) dan Uji Aktivitas Antioksidan dengan Metode DPPH (1,1-difenil-2-pikrilhidrazil) Rachel Bintang; Ghalib Syukrillah Syahputra; Sri Budiasih
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 3 No. 4 (2025): Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v3i4.5750

Abstract

Thick leaf (Glochidion superbum) is a medicinal plant traditionally utilized by the community of East Panjang Island for the treatment of wounds, pain, and ulcers. This research was conducted to isolate the major compounds present in the ethyl acetate fraction of thick leaf and to assess its antioxidant activity using the DPPH method. The plant leaves were first cleaned, dried, and powdered, followed by maceration extraction using methanol, which resulted in an extract yield of 16.42%. The crude extract was fractionated by column chromatography using EtOAc and MeOH eluents with ratios of 9:1 (K1), 4:1 (K2), 1:4 (K3), and 1:9 (K4). UV–Vis spectrophotometric analysis showed an absorption peak at 288 nm, indicating the presence of phenolic compounds, identified as ferulic acid. Antioxidant testing using the DPPH method showed IC₅₀ values for fractions K1, K2, K3, and K4 of 12.981, 5.159, 9.658, and 10.971 µg/mL, respectively, with vitamin C as a positive control (3.563 µg/mL). Fraction K2 showed the strongest antioxidant activity. These results indicate that thick leaf contains ferulic acid with very strong antioxidant activity and has potential as a natural antioxidant source.
Identifikasi Drug Related Problems (DRPs) Pada Pasien Pediatri Penderita Epilepsi Rawat Jalan Di RSUD Embung Fatimah Kota Batam Faizah Zalsabila; Aprilya Sri Rachmayanti; Ghalib Syukrillah Syahputra
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 3 No. 4 (2025): Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v3i4.5753

Abstract

Epilepsy is one of the most common chronic neurological disorders in children. Long-term use of antiepileptic drugs carries the risk of Drug Related Problems (DRPs) such as drug interactions, inappropriate dosing, and untreated indications. This study aimed to identify the types and incidence of DRPs in pediatric epilepsy outpatients at Embung Fatimah General Hospital, Batam. This was a descriptive, non-experimental study with a retrospective design. Data were collected from pediatric medical records (<18 years) between January–December 2024, with a total of 45 patients. DRPs were identified using the American Society of Hospital Pharmacist (ASHP) classification. Of 45 patients, the majority were aged 1–5 years (38%) and female (53%). The most frequently used antiepileptic drug was sodium valproate (56.36%). Identification DRPs included drug interactions (63.16%), untreated indications (5.26%), and inappropriate drug selection (5.26%). No cases of overdose or failure to receive medication were found. The most dominant DRP in pediatric epilepsy patients was drug interactions, particularly between valproic acid and folic acid.
Uji Efektifitas Fraksi Daun Setebal (Glochidion superbum) terhadap Penyembuhan Luka Sayat pada Mencit Putih Jantan (Mus musculus L.) Rivelino William Putra Nazara; Habibie Deswilyaz Ghiffari; Ghalib Syukrillah Syahputra; Desy Gusmali Maniarti; Roza Erda
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 4 No. 1 (2026): Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v4i1.5895

Abstract

Wounds can be defined as the loss and damage of anatomical cells or skin function. Wound healing consists of coagulation, inflammation, proliferation, and remodeling stages. This study aims to determine the effectiveness of the leaf fraction of the thick (Glochidion superbum) on wound healing in male white mice (Mus musculus). This study is experimental. This study used 24 male mice that were given a 10 mm long cut wound. Fractionation was carried out using the liquid-liquid extraction method. Fractionation used 3 different types of solvents, namely methanol, ethyl acetate, and n-hexane. The results showed that the ethyl acetate fraction had a faster wound healing effectiveness than the other groups. The ethyl acetate fraction contains a phenolic compound, namely methyl gallate. Methyl gallate has an important role in wound healing. Methyl gallate has the potential to be an antibacterial, antioxidant, and anti-inflammatory. The results of the Bonferroni post-hoc statistical analysis confirmed the effectiveness of the ethyl acetate fraction in faster wound healing. The thick leaf fraction was effective in healing incisions in male white mice. The ethyl acetate fraction was more effective in accelerating incision healing.
ANALISIS TERAPI ANTIPSIKOTIK TERHADAP KUALITAS HIDUP PASIEN REHABILITASI NAPZA DI LOKA REHABILITASI BADAN NARKOTIKA NASIONAL BATAM I Gusti Ngurah Agung Artawijaya; Nahrul Hasan; Diani Mega Sari; Ayu Amelia; Ghalib Syukrillah Syahputra
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 10 No 2 (2025): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/sgmf8w86

Abstract

Antipsychotic therapy is often administered to NAPZA rehabilitation patients with comorbid mental disorders such as schizophrenia, bipolar disorder, or major depression. This study aims to analyze the effect of antipsychotic therapy on the quality of life of NAPZA rehabilitation patients at the BNN Batam Rehabilitation Center. The research method used total sampling with a sample size of 26 respondents. Quality of life was measured using the WHOQOL-BREF questionnaire. The results showed that the majority of respondents were male (92.3%) aged 18–49 years, with the most common diagnosis being paranoid schizophrenia (84.6%). The dominant therapy given was second-generation antipsychotics (92.3%). There was an increase in the average quality of life score across all domains, from 58.68 to 73.72 after therapy. The paired t-test showed a significant difference between quality of life before and after therapy (p = 0.000). However, the chi-square test showed no significant relationship between type of therapy and duration of rehabilitation with improvement in quality of life (p ≥ 0.05). In conclusion, antipsychotic therapy significantly improves the quality of life of NAPZA rehabilitation patients.
TERIH SEHAT Pemeriksaan Kesehatan di Kampung Terih Kelurahan Sambau Kecamatan Nongsa Kota Batam Habibie Deswilyaz Ghiffari; Didi Yunaspi; Roza Erda; Ghalib Syukrillah Syahputra; Tommy Julianto; Sri Hainil; Sri Budiasih; Ayu Amelia; Rury Trisa Utami; Desy Maniarty Gusmali
Jurnal Pengabdian Masyarakat Bangsa Vol. 4 No. 5 (2026): Juli
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v4i5.4733

Abstract

Pemeriksaan kesehatan berkala merupakan langkah penting dalam deteksi dini risiko penyakit tidak menular, terutama yang berkaitan dengan sistem metabolik dan kardiovaskular. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk  melakukan pemeriksaan tekanan darah, kadar kolesterol, asam urat, dan gula. Data dikumpulkan melalui pemeriksaan langsung di lapangan darah pada 35 individu dewasa. Hasil menunjukkan bahwa 51,4% responden memiliki tekanan darah di atas normal (>140/90 mmHg), 57,1% mengalami hiperkolesterolemia (>200 mg/dL), 45,7% memiliki kadar asam urat tinggi (>7 mg/dL untuk laki-laki dan >6 mg/dL untuk perempuan), dan 37,1% mengalami hiperglikemia (>140 mg/dL). Selain itu, beberapa kasus ekstrem ditemukan, seperti kadar gula darah mencapai 400 mg/dL dan kolesterol hingga 303 mg/dL. Temuan ini menunjukkan tingginya prevalensi faktor risiko penyakit kronis di kalangan responden. Oleh karena itu, upaya promotif dan preventif melalui edukasi gaya hidup sehat,menghindari makanan yang dapat menyebabkan peningkatan kadar penyakit dan pemeriksaan rutin sangat disarankan untuk menurunkan angka kejadian penyakit degeneratif.
Co-Authors Aliya Nur Hasanah Amelia, Ayu Annisa Laili Oktaviyani Aprilya Sri Rachmayanti Arie Vonikartika Ayu Amelia DAYAR ARBAIN Delladari Mayefis Delladari Mayefis Desy Gusmali Maniarti Desy Maniarti Gusmali Desy Maniarty Gusmali Dhia Suhailah Diani Mega Sari Didi Yunaspi Eka Febriyanti Eka Febriyanti Elfasyari, Trie Yuni Faizah Zalsabila Ghiffari, Habibie Deswilyaz Hasan, Nahrul Henny Rachdianti Tjahjono Suyarto Henny Rachdiati I Gusti Ngurah Agung Artawijaya Ibnu Rusyd Julianto, Tommy Lyna Elvira Meilanda , Rastria Meilanda, Rastria Mutiara Ayudia Astuti Nahrul Hasan Nela Yulia Putri Nurwijayanti Piter Piter Rachel Bintang Rivelino William Putra Nazara Roza Erda Rury Trisa Utami Shinta Cania Maiza Shinta Sari Dewi Sri Budiasih Sri Budiasih Sri Hainil Sri Marlina, Sri Suci Fitriani Sammulia Suhaera Suhaera Suhaera Suhaera Yoppi Iskandar Yunisa Friscia Yusri Zahara Zahara