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All Journal Farmaka Indonesian Journal of Pharmaceutical Science and Technology IDJP (Indonesian Journal of Pharmaceutics) Indonesian Food Science and TechnologyJournal Majalah Farmasetika ad-Dawaa : Journal of Pharmaceutical Sciences Community Development Journal: Jurnal Pengabdian Masyarakat Indonesian Journal of Biological Pharmacy Journal of The Indonesian Society of Integrated Chemistry Kartika : Jurnal Ilmiah Farmasi
Anis Yohana Chaerunisaa, Anis Yohana
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

 1 
Isolation And Characterization of Physicochemical Properties of Mucilago Gedi Leaf (Abelmoschus manihot L. Medik) Rindengan, Elvie Rifke; Abdassah, Marline; Chaerunisaa, Anis Yohana
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 3 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (444.952 KB) | DOI: 10.15416/ijpst.v5i3.16744

Abstract

The aim of this research was to isolation of mucilage from gedi leaf (Abelmoschus manihot L. Medik) and characterized physicochemical properties. The isolation result was yellowish brown powder that swelling and dissolves slowly in water, but does not dissolve in ethanol, methanol, acetone and ether. The yield is 1.33%. Swelling index value 100% and viscosity 28 ± 2.65 mpas, pH 7.1. Proximate analysis showed 10.46% water content, 38.80% ash, 14.66% protein, 0.69% fat, 35.38% carbohydrate Water holding capacity (WHC) and  oil holding capacity (OHC) of musilago are respectively 4.23 ± 0.18 and 0.65 ± 0.14. Viscosity, Swelling index, WHC and OHC mucilage gedi leaf  may be considered as pharmaceutical excipients.Keywords: Mucilage, Abelmoschus manihot, swelling, viscosity
Solvent Type Effect on Preparation of Ethyl Cellulose Microparticles Muhaimin, Muhaimin; Chaerunisaa, Anis Yohana
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 3 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i3.38460

Abstract

The purpose of this study was to investigate effect of solvent type on solidification rate of ethylcellulose (EC) microparticles and particle size/distribution of emulsion droplets/hard microparticlesduring the solvent evaporation process using focused beam reflectance measurement (FBRM). ECmicroparticles were prepared by an O/W-solvent evaporation method using various solvents, includingdichloromethane, dichloromethane:methanol (1:1), ethyl acetate, and chloroform. The particle size/distribution of emulsion droplets/hard microparticles was monitored by FBRM. The morphology ofEC microparticles was characterized by scanning electron microscopy (SEM). The transformation ofemulsion droplets into solid microparticles for all solvents occured within the first 10-60 min. Thesquare weighted mean chord length of EC microparticles which were prepared using chloroform wassmallest value, but the chord counts was no the highest. The chord length distribution (CLD) measuredby FBRM showed that microparticles with a larger diameter give a wider CLD and a lower peaknumber of particles. SEM data shows that the morphology of microparticles was influenced by type ofsolvent. FBRM can be used to monitor the development of microparticle CLDs online and detect thetransformation of emulsion droplets into solid microparticles during the solvent evaporation process.The microparticle CLD and transformation processes are influenced by the type of solvent.
Phytochemical Screening And Antioxidant Activity Test of Lupun Root (Poikilospermum suaveolens (Blume) Merr) from South of Borneo Mardiana, Lia; Milanda, Tiana; Hadisaputri, Yuni Elsa; Chaerunisaa, Anis Yohana
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.51350

Abstract

Lupun root is the local name for Poikilospermum suaveolens (Blume) Merr. in the Aranio region, South of Borneo, Indonesia. P.suaveolens is a medicinal plant traditionally used to treat various ailments and to enhance the body’s immune function. This study aimed to investigate the secondary metabolites and antioxidant capacity of the ethanol extract derived from the root of Lupun (P. suaveolens). Samples were collected from Aranio, South Borneo. Extraction was performed by maceration using 96% ethanol. The analysis included phytochemical screening and evaluation of antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay measured by a UV-Vis spectrophotometer. Phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, and phenolic compounds in the Lupun root extract. The antioxidant assay showed an IC50 value of 20.44 µg/mL, indicating strong antioxidant potential of the ethanol extract. These results highlight the plant’s promise as a candidate for pharmaceutical development.
Co-Authors Ade Zuhrotun Andrie, Agus Apriani, Diana Kurnia Aprilian, Salsa Barmi Hartesi Chaniago, Rahadatul Aisy Dwiya, Reiva Farah ELVIE RIFKE RINDENGAN, ELVIE RIFKE Erlianti, Karina Handayani, Retty Harsanti, Bunga Dacilia Hazrina, Aghnia Hindun, Siti Khairinisa, Miski Aghnia Kurniawan Syah, Insan Sunan Maisyarah, Intan Timur Mardiana, Lia Marline Abdassah, Marline MAYANG KUSUMA DEWI, MAYANG KUSUMA Muhaimin Muhaimin Patihul Husni Raden Maya Febriyanti Sriwidodo Sriwidodo, Sriwidodo TIANA MILANDA Tina Rostinawati Uce Lestari Widayanti Supraba Wulantresna, Dewi Yoga Windhu Wardhana Yoga Windu Wardhana, Yoga Windu Yuni Elsa Hadisaputri