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THE POTENTIAL USE OF Phaleria macrocarpa LEAVES EXTRACT AS AN ALTERNATIVE DRUG FOR BREAST CANCER AMONG WOMEN LIVING IN POVERTY Amir, Hermansyah; Murcitro, Bambang Gonggo; Ahmad, Ahmad Shamsudin; Kassim, Murni Nur Islamiah
ASIAN JOURNAL FOR POVERTY STUDIES (AJPS) Vol 3, No 2 (2017)
Publisher : Regional Network on Poverty Eradication

Show Abstract | Download Original | Original Source | Check in Google Scholar

Cancer is recognized as global threat to human development and it was estimated that in 2030 there will be 22.2 million new cases of cancer and 12.7 million cancer-related deaths worldwide. Herbal medicine plant till this day all over in the word is still the main source and one of the most important fields of traditional medicine agents to fight breast cancer. The usage of plants is still important because has its own beaviour advantages such as low toxicity, easy to get, cheap and has less side effect if it is used in a right. One of this plant it has been used as a traditional medicine is a Phaleria macrocarpa (Scheff) Boerl) also known as Mahkota Dewa from Papua island. It has been used traditionally for treatment of cancers in Indonesia and also to cure many diseases. The therapeutic effect of Phaleria macrocarpa (Scheff) Boerl, is related to the its bioactive compounds contents. There are many reported compounds from Phaleria macrocarpa (Scheff) Boerl, which are found, reported and published such as Icariside, phalerin, mangiferin, gallic acid, 29-Norcucurbitacin, gentiobioside and glucoside. All compounds reported above have already published as anticancer agents,where anticancer activity were detected and showed against Hela cells, leukemia cells, cervical cancer, breast cancer, and L1210 cells. Research on Phaleria macrocarpa (Scheff.) Boerl fruit and leaves merit have been done and published, however, there are very limited research on linked correlation between the concentration of compounds and its the cytotoxicity Â level. Because of that, research about correlation level of Phaleria macrocarpa (Scheff) Boerl leaves extract still need to investigate to find the relationship between them in the goal to investigate alternative low cost herbal medicine agents to fight breast cancer especially useful for low income people, thus, information about Phaleria macrocarpa (Scheff.) Boerl.Leaves became more complete. Cytotoxicity properties of samples against breast cancer cell lines was performed by using the MTT assay against MCF-7 cell line. The correlation between concentration of crude and cytotoxic activity was interpreted by statistical analyses. The study showed that Phaleria macrocarpa (Scheff) Boerl.) leaves extracts showed cytoxicity activity against breast cancer MCF7 cell lines. Correlation between concentration of extract and cytotoxicity property (absorbance value) were founded in weak relationship (R = -0.37181). It could be effect of many different compounds in the Phaleria macrocarpa (Scheff) Boerl.) leaves methanol extracts may cause the pharmacological interactions, so lower or higher concentration will be antagonistic effect on absorbance or cell viability.Further study on its mechanism pathway on revealing against breast cancer could be explored. Furthermore, the natural product derived from Phaleria macrocarpa (Scheff) Boerl.) leaves extracts have potential use in cheap alternative agents against breast cancer

APLIKASI TIGA JENIS PUPUK ANORGANIK TERHADAP PERTUMBUHAN DAN HASIL TIGA VARIETAS CABAI HIBRIDA UNIB (CAPSICUUM ANNUUM L.) Maryono, Andi Tri; Ganefianti, Dwi Wahyuni; Murcitro, Bambang Gonggo; Rustikawati, Rustikawati; Gusmara, Herry; Mukhtasar, Mukhtasar; Salamah, Umi
AGRITROP Vol 17, No 2 (2019): Agritrop: Jurnal Ilmu-Ilmu Pertanian
Publisher : Universitas Muhammadiyah Jember

Penggunakan benih lokal yang ditanam secara terus menerus telah menyebabkan produksi rendah. Upaya untuk meningkatkan produktivitas cabai yaitu dengan menggunakan benih hibrida unggul yang memiliki produktivitas yang tinggi, umur panen genjah, memiliki daya tahan terhadap hama dan penyakit, dan buah yang disukai para konsumen serta daya adaptasi lingkungan yang tinggi. Rancangan Percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) pola faktorial, yang terdiri atas 2 faktor. Faktor pertama adalah jenis pupuk terdiri atas 3 jenis yaitu : NPK Mutiara (16:16:16) = 300 kg/ha, Urea+KCl+TSP = 250 kg/ha+500 kg/ha+400 kg/ha, ½ dosis Urea+½ dosis KCl+½ dosis TSP+½ dosis NPK Mutiara (16:16:16) = 125 kg/ha+250 kg/ha+200 kg/ha+150 kg/ha. Faktor kedua adalah Varietas cabai hibrida terdiri atas 3 varietas yaitu : UNIB C H73, UNIB C H65 dan, UNIB C H13. Dari kedua faktor tersebut diperoleh 9 pasang perlakuan, diulang 5 kali sehingga diperoleh 45 satuan percobaan, yang terdiri atas 2 tanaman sehingga didapatkan 90 tanaman.Hasil penelitian menunjukkan bahwa aplikasi pupuk anorganik urea+KCl+TSP menghasilkan jumlah buah total tertinggi pada varietas UNIB C H65. Aplikasi pupuk anorganik Urea+KCl+TSP menghasilkan tinggi tanaman yang lebih tinggi dari aplikasi pupuk anorganik lainnya, dengan umur berbunga yang lebih cepat dibandingakan aplikasi pupuk anorganik lainnya. Aplikasi pupuk anorganik pada varietas UNIB C H73 menghasilkan diameter batang lebih besar, umur panen yang relatif cepat, panjang tangkai buah lebih panjang, panjang buah terpanjang dan bobot buah segar terberat dibandingkan varietas lainnya.

Delivery of Arbuscular Mycorrhiza Fungus Spores via Seed Coating with Biodegradable Binders for Enhancement of the Spores Viability and Their Beneficial Properties in Maize Marwanto, Marwanto; Bustaman, Hendri; Handajaningsih, Merakati; Supanjani, Supanjani; Murcitro, Bambang Gonggo; Salamah, Umi
Akta Agrosia Vol 23, No 1 (2020)
Publisher : Faculty of Agriculture, The University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31186/aa.23.1.1-10

biodegradable polymer such as PVA is considered the most promising candidates for developing the sustainable sticker. The objective of this study was to determine the most suitable PVA + TS blends as adhesives agent for AMF spores inoculation via seed coating which can enhance the spores viability and their beneficial properties in maize. The polythene bag experiment was performed in a screen house of the Department of Plant Protection Faculty of Agriculture, University of Bengkulu Indonesia in 2015. Six adhesive blends were employed: 100% PVA + 0% TS, 75% PVA + 25% TS, 50% PVA + 50% TS, 25% PVA + 75% TS, 0% PVA + 100% TS, and no coating. The six experimental treatments were laid out in a completely randomized design with three replications. The results show that root colonization, AMF spore population, and shoot dry weight in 75% PVA + 25% TS were equal to those in 100% PVA. Root colonization, AMF spore population, shoot P content, and shoot P concentration were greater for 50% PVA + 50% TS than 100% PVA, 100% TS, and no coating. A mixture of 50% PVA + 50% TS was considered the preferred sticker. Thus, the tapioca starch can be used to substitute 25 - 50% of the PVA used without reducing AMF inoculant adhering to seed.Keywords: polymeric seed coating, seed coating formulation, arbuscular mycorrhizal fungi, sustainable coating adhesive, seed inoculation, seed inoculant

PERCONTOHAN BUDIDAYA KEDELAI HITAM DI LAHAN SAWAH DESA KEMUMU DAN OLAHAN HASILNYA Murcitro, Bambang Gonggo; Pujiwati, Hesti; Tutuarima, Tuti
PEDULI: Jurnal Ilmiah Pengabdian Pada Masyarakat Vol 5 No 2 (2021)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37303/peduli.v5i2.360

This devotional activity aims to improve farmers' skills in the cultivation of black soybeans and increase the selling value of black soybeans which can ultimately increase farmers' incomes in Kemumu Village. Devotional activities are designed in 3 types of activities that are mutually sustainable, namely (1) education and extension of black soybeans, (2) the manufacture of black soybean planting experiments, and (3) training and the making of black soybean processing. The results of the activity showed that the education and counseling carried out by the devotional team was able to increase knowledge about black soybeans both planting techniques and processing of seed products. Cultivation of soybean plants and the manufacture of processed soybean seeds into tempe, tofu, and soy sauce have been successfully carried out by the farmer's group of Kemumu Village, North Bengkulu. The result achieved by the black soybean variety Detam 4 is 1.39 tons/ha. To follow up on this activity, the proposed suggestions include: (1) in the future members of the target farming group are expected to continue to carry out the practice of cultivating black soybeans on a wider scale (2) members of the target farming group to keep making tempe and soybeans on an industrial scale to increase household income, (3) to the government to provide a channel of funds to meet adequate equipment resources in the production of tofu and industrial-scale tempe.

Induksi Umbi Mikro Kentang Secara In Vitro Pada Suhu Tinggi Dengan Beberapa Tuber Promoter Usman Kris Joko Suharjo; Bambang Gonggo Murcitro; Tunjung Pamekas; Haryuni Haryuni
Biogenesis: Jurnal Ilmiah Biologi Vol 5 No 1 (2017)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v5i1.3435

Potato microtubers are the miniature of conventional seed tubers grown in the field. Producing potato microtuber in vitro at high temperature by applying many kinds of tuber promoting substances is similar to producing potato in the field at low elevation by applying the same tuber promoting substances. The objective of this research was to evaluate the performance of seven tuber promoters in inducing potato microtubers at high temperatures. Micro cuttings (6 weeks old) were grown at the liquid media of MS for stolon induction. Six weeks afterward, the media were moved to microtuber inducing media supplemented with tuber promoters ((FD, FD+10 COU, FD+20 COU, FD+30 COU, FD+40 COU, FD+50 COU, and IPB). The media were incubated in the dark at 20 + 2oC and 29 + 2oC. The results showed that, in general, high temperature inhibited crop growth and tuber formation. Individually, tuber promoter formula significantly affected microtuber emergence, in which IPB showed the slowest treatment in producing microtubers, the smallest number of tuber produced, and the smallest size of tubers. The interaction between temperature and tuber promoters were significantly affected the tuber formation, in which the fastest tuber formation (7,0 days ) was found in FD + 40 COU and the highest percentage of plant producing tubers was found in FD + 30 COU. Moreover, the highest number of microtuber and the heaviest weight of microtuber were found in FD (no Coumarin). It was safely concluded that all tuber promoters were best performed at low temperature. Should anyone wish to make those tuber promoters work better at high temperature, it is recommended to increase the concentration of Coumarin added to the formula of tuber promoting substances.

Uji Coba Empat Varietas Kedelai di Kawasan Pesisir Berbasis Biokompos Yudhi Harini Bertham; Nur Aini; Bambang Gonggo Murcitro; Abimanyu Dipo Nusantara
Biogenesis: Jurnal Ilmiah Biologi Vol 6 No 1 (2018)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v6i1.4144

This study aims to obtain soybean varieties that are able to grow well and produce high in biocomposite coastal areas. This study was compiled using Randomized Block Design (RAKL) with single factor consisting of four varieties of soybeans namely Wilis, Grobogan, Detam I and Detam II. The results showed that the varieties of Wilis produce the highest plant height 63,13 cm, the highest percentage of pods per plant is 91,12%, the highest number of seeds per plant is 249,56 pieces, the heaviest seed weight per plant is 30,92 gram, while the Grobogan which produce the heaviest dry weight is 7,92 g, the highest K absorption is 0,22 g and the highest 100 seed weight is 18,00 g. Thus, the varieties of Wilis and Grobogan have higher adaptation rates than the Detam 1 and Detam II varieties, which has the potential to be developed in coastal areas.

Sistem Pakar Menentukan Kekurangan Unsur Hara Dan Penggunaan Pupuk Pada Tanaman Jagung Pasca Penanaman Menggunakan Metode Forward Chaining (FC) Ahmad Fauzi; Desi Andreswari; Bambang Gonggo Murcitro
Jurnal Pseudocode Vol 6, No 2 (2019): Volume 6 Nomor 2 September 2019
Publisher : Universitas Bengkulu

Jagung merupakan salah satu tanaman pangan yang banyak dibudidayakan di dunia. Indonesia salah satu negara yang memiliki potensi yang sangat besar dalam sektor Pertanian, maka diperlukan berbagai upaya untuk meningkatkan hasil panen salah satunya dengan melakukan pemupukan yang baik dan benar. tanaman jagung sangat rentan dengan kekurangan unsur hara, Penelitian ini bertujuan untuk menghasilkan Sistem pakar menentukan kekurangan unsur hara dan penggunaan pupuk pada tanam jagung pasca penanaman menggunakan metode forward chaining (FC). Gejala yang terdapat pada sistem sebanyak 32 gejala dari seluruh gejala yang ada baik pada daun, batang, akar dan tongkol jagung. Sistem pakar ini dibuat menggunakan MySQL sebagai database, PHP (Hypertext Preprocessor) untuk bahasa pemrograman dan UML (Unified Modeling Languange ) sebagai pemodelan perancangan perangkat lunak (software). Pengujian sistem dilakukan dengan dua tahap yaitu Black Box Testing dan White Box Testing, sedangkan untuk pengujian kelayakan sistem menggunakan Skala Liker dan Probabiltas Klasik. Jumlah responden yang diajukan sebanyak 31 orang, kuesioner terdiri atas 8 pertanyaan. 4 tentang tampilan sistem dan 4 tentang kemudahan menggunakan sistem. perolehan yang didapat untuk tampilan sistem dengan rata-rata persentase 90,49 % termasuk ke dalam interval “Sangat Baik”, kemudahan menggunakan aplikasi dengan rata-rata persentase sebesar 82,67 % termasuk ke dalam interval “Baik” dan hasil dari uji kelayakan diperoleh presentase sebesar 53,12 jadi sistem dapat dikatakan Layak.Kata Kunci: Forward Chaining, MySQL, PHP, Unsur Hara, Tanaman Pangan.

APLIKASI TIGA JENIS PUPUK ANORGANIK TERHADAP PERTUMBUHAN DAN HASIL TIGA VARIETAS CABAI HIBRIDA UNIB (Capsicuum annuum L.) Andi Tri Maryono; Dwi Wahyuni Ganefianti; Bambang Gonggo Murcitro; Rustikawati Rustikawati; Herry Gusmara; Mukhtasar Mukhtasar; Umi Salamah
AGRITROP Vol 17, No 2 (2019): Agritrop: Jurnal Ilmu-Ilmu Pertanian
Publisher : Universitas Muhammadiyah Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32528/agritrop.v17i2.2396

Penggunakan benih lokal yang ditanam secara terus menerus telah menyebabkan produksi rendah. Upaya untuk meningkatkan produktivitas cabai yaitu dengan menggunakan benih hibrida unggul yang memiliki produktivitas yang tinggi, umur panen genjah, memiliki daya tahan terhadap hama dan penyakit, dan buah yang disukai para konsumen serta daya adaptasi lingkungan yang tinggi. Rancangan Percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) pola faktorial, yang terdiri atas 2 faktor. Faktor pertama adalah jenis pupuk terdiri atas 3 jenis yaitu : NPK Mutiara (16:16:16) = 300 kg/ha, Urea+KCl+TSP = 250 kg/ha+500 kg/ha+400 kg/ha, ½ dosis Urea+½ dosis KCl+½ dosis TSP+½ dosis NPK Mutiara (16:16:16) = 125 kg/ha+250 kg/ha+200 kg/ha+150 kg/ha. Faktor kedua adalah Varietas cabai hibrida terdiri atas 3 varietas yaitu : UNIB C H73, UNIB C H65 dan, UNIB C H13. Dari kedua faktor tersebut diperoleh 9 pasang perlakuan, diulang 5 kali sehingga diperoleh 45 satuan percobaan, yang terdiri atas 2 tanaman sehingga didapatkan 90 tanaman.Hasil penelitian menunjukkan bahwa aplikasi pupuk anorganik urea+KCl+TSP menghasilkan jumlah buah total tertinggi pada varietas UNIB C H65. Aplikasi pupuk anorganik Urea+KCl+TSP menghasilkan tinggi tanaman yang lebih tinggi dari aplikasi pupuk anorganik lainnya, dengan umur berbunga yang lebih cepat dibandingakan aplikasi pupuk anorganik lainnya. Aplikasi pupuk anorganik pada varietas UNIB C H73 menghasilkan diameter batang lebih besar, umur panen yang relatif cepat, panjang tangkai buah lebih panjang, panjang buah terpanjang dan bobot buah segar terberat dibandingkan varietas lainnya.

PENERAPAN TEKNOLOGI PUPUK HAYATI UNTUK BUDIDAYA KEDELAI DI KAWASAN PESISIR Abimanyu Dipo Nusantara; Yudhi Harini Bertham; Bambang Gonggo Murcitro
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 6 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i6.2008-2013

Selama ini kawasan pesisir yang terletak di Kelurahan Beringin Raya kurang termanfaatkan untuk budidaya pertanian dan sebagian dibiarkan menjadi semak belukar, meskipun sebagian besar masyarakatnya berprofesi sebagai petani. Hal ini karena kawasan pesisir memiliki tanah dengan karakteristik yang kurang mendukung untuk pertumbuhan komoditi pertanian. Oleh karena itu, diperlukan teknologi khusu agar tanaman bisa tumbuh dan berproduksi dengan baik di kawasan pesisir, salah satunya adalah apliaksi pupuk hayati. Kegiatan pengabdian ini bertujuan untuk meningkatkan pengetahuan masyarakat mitra tentang pupuk hayati dan aplikasinya melalui penyuluhan dan pelatihan serta pendampingan. Luaran yang dicapai dalam pengabdian ini adalah meningkatnya pengetahuan Kelompok Tani Wanita Rezeki Bersama tentang pupuk hayati dan aplikasinya terhadap tanaman kedelai. Selain itu, adanya kegiatan pengabdian mampu membuat anggota KWT berminat untuk menanam kedelai menggunakan pupuk hayati. Anggota kelompok KWT juga telah bisa mengaplikasikan pupuk hayati.

Runoff Coefficient in the Air Bengkulu Watershed and the Evaluation of the Existing Spatial Planning Sulistyo, Bambang; Adiprasetyo, Teguh; Murcitro, Bambang Gonggo; Purwadi, Agus Joko; Listyaningrum, Noviyanti
Indonesian Journal of Geography Vol 56, No 2 (2024): Indonesian Journal of Geography
Publisher : Faculty of Geography, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijg.91397

Runoff coefficient plays a crucial role in estimating the peak discharge of a river basin. Therefore, this research aimed to investigate runoff coefficient in the Air Bengkulu watershed based on temporal land cover data and evaluate the existing spatial planning. Land cover data from 1998, 2002, 2016, and 2023, with spatial patterns derived from current regional planning were used. The temporal and spatial pattern-based runoff coefficients were determined using land cover data and spatial pattern function, respectively. Meanwhile, descriptive and comparative methods were adopted based on time. The calculated runoff coefficient was 0.073, 0.093, 0.276, and 0.273 for 1998, 2002, 2016, and 2023, while the value obtained based on spatial patterns was 0.306. Additionally, a general trend of increasing the values over time was observed. Land cover change, particularly the decline of forest areas and the expansion of settlement and plantation, contributed to the rising runoff coefficient. The results showed that runoff coefficient (0.306) exceeded the current land cover, similar to other analyses with higher runoff in the predicted scenario. This research suggested a need for a more detailed classification system and scale to accommodate land cover types with relatively low runoff coefficient. In risk assessment, land cover-like spatial patterns with low runoff coefficient should be placed as capacity other than vulnerability components.

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