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All Journal Global Medical and Health Communication Universa Medicina Jurnal Biomedika dan Kesehatan Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Dharma Bhakti Ekuitas Bioscientist : Jurnal Ilmiah Biologi JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Asian Journal of Healthcare Analytics Jurnal Pengabdian Nasional (JPN) Indonesia Jurnal Kedokteran Meditek
Eveline Margo, Eveline
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Universa Medicina

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Management of anemia among patients in intensive care units Margo, Eveline
Universa Medicina Vol 27, No 2 (2008)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2008.v27.78-86

Abstract

Anemia is frequently encountered in critically-ill patients in the intensive care unit (ICU). Anemia may occur both at the time of admission, during treatment and after discharge from the ICU. The causes are multifactorial and include acute blood loss, blood loss from diagnostic testing and blunted red blood cell production. Blood transfusions are frequently given to patients in the ICU to treat low hemoglobin levels due to either acute blood loss or subacute anemia associated with critical illness. Although blood transfusion is a life-saving therapy, evidence suggests that it may be associated with an increased risk of morbidity and mortality. A feature of anemia of critical illness is lack of appropriate elevation of circulating erythropoietin concentrations in response to physiological stimuli. One important concern is that anemia may not be well tolerated by a critically ill patient. A number of blood conservation strategies exist that may mitigate anemia in hospital patients and limit the need for transfusion. These strategies include the use of hemostatic agents, hemoglobin substitutes and blood salvage techniques, the reduction of blood loss associated with diagnostic testing, the use of erythropoietin and the use of restrictive blood transfusion triggers. In this article we review the prevalence of anemia during critical illness specifically among patients in the ICU, and discuss the various factors that contribute to its development, the prevention and treatment of anemia by appropriate red cell transfusion and the place of erythropoietin in treatment.
Hypoglycemic effect of Phaleria macrocarpa (Scheff.) Boerl dry extract in healthy adults Meiyanti, Meiyanti; Margo, Eveline; Pusparini, Pusparini; Merijanti, Lie Tanu; Lesmana, Alvina
Universa Medicina Vol 37, No 3 (2018)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (828.359 KB) | DOI: 10.18051/UnivMed.2018.v37.195-202

Abstract

BackgroundThe prevalence of diabetes in Indonesia continues to increase and causes many complications. Fruits of Phaleria macrocarpa (Scheff.) Boerl. (PM) are used in the traditional health system of the Indonesians, as effective remedy in the management of diabetes mellitus. The aim of this study was to evaluate the effect and magnitude of doses of PM dry fruit extract (PME) on blood glucose levels in healthy adults.MethodsThis research was of pre-posttest design involving 30 healthy volunteer subjects aged 20-55 years receiving glucose loads. At pre-test the subjects were given orally 75 g glucose, and at post-test they were given PME at doses of 125 mg and 250 mg. Data collection included anthropometric examination and blood glucose level. The area under the curve (AUC) of blood glucose levels was measured at 0, 15, 30, 60, 120 and 180 minutes. Data analysis was performed using paired t-test with p <0.05.ResultsThe percentage of reduction in AUC between pre- and post-test after administration of PME 125 mg was 12.1% and significant (p=0.000). But the percentage of reduction in AUC between pre- and post-test after administration of PME 250 mg was 4.07% and not significant (p=0.06). The reduction in AUC between post-test PME 125 mg vs PME 250 mg showed significant results (p=0.011).Conclusion This study demonstrated that a dose of 125 mg Phaleria macrocarpa (Scheff.) Boerl. dry extract has a hypoglycemic effect in healthy adults, and may therefore be suitable for use as traditional anti-diabetic drug.
Co-Authors Alvina Lesmana, Alvina Anastasya, Karina Shasri Anggraeni Adiwardhani Erlani Kartadinata, Erlani Faradilla, Meutia Atika Fransisca Chondro, Fransisca Handayani, Astri Husnun Amalia Juni Chudri Kartadinata, Noviani Kurniasari Lie Tanu Merijanti, Lie Tanu Meiyanti Meiyanti Meiyanti, Meiyanti Monica Dwi Hartanti, Monica Dwi Murthi, Aditya Prajgayatri, Galena Devi Prasetyaningsih, Noviani Pusparini Pusparini Rachmadanti, Tharisa Reni Zuraida sisca Wibowo, Elsi Septira Witjaksana, Riani Xavierees, Endrico Yohana Yohana Yohana Yohana