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All Journal Jurnal Sains dan Teknologi Farmasi Jurnal Farmasi Higea Media Karya Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research JURNAL MEDIA KESEHATAN Journal of Nursing and Public Health (JNPH) Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Health Science JAFP (Jurnal Akademi Farmasi Prayoga) Jurnal Pharmacopoeia Riset Informasi Kesehatan Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan Jurnal Ilmiah Farmasi Simplisia Proceeding of Bengkulu International Conference on Health

Krisyanella Krisyanella

Study Program Of Pharmacy, Poltekkes Kemenkes Bengkulu, Indonesia

Author-ID : 6784625

Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Pembuatan Dan Karakterisasi Serta Penentuan Kadar Flavonoid Dari Ekstrak Kering Herba Meniran (Phyllanthus niruri L.) Krisyanella Krisyanella; Nana Susilawati; Harrizul Rivai
Jurnal Farmasi Higea Vol 5, No 1 (2013)
Publisher : STIFARM Padang

Preparation and characterization of dried herb extract of meniran (Phyllanthus niruri L.) has been done. Dried extract was made by adding lactose with a certain ratio, with the ratio of extract and lactose are: 1 : ½ (F1); 1 : 1 (F2); 1 : 1½ (F3); 1 : 2 (F4). Characters abserved were specific and non specific character of the dried extract. Non specific character of dry extract include loss in drying values, real density, compressed density, total ash, acid insoluble ash content. Specifik characterization extract includes identities, organoleptic, levels of water soluble exstract the levels of compounds soluble in ethanol and levels of chemical constituents. Dried extract mode with F3 has better characteristics than the other formulas. The name of the extract is Extractum Phyllanthus niruri L.Siccum. The extract was in the form of dry powder, dark brown, odor like meniran crude herb with a strong flavor. Levels of water soluble extract was 55.1077 % b/b ± 11.2218 % b/b while levels of ethanol-soluble extract 18.7214 % b/b ± 0.6733 % b/b. flavonoid levels of the dried extract was 0.2413 % w/w.

Karakterisasi Ekstrak Air Daun Dewa (Gynura pseudochina (L.) DC Dan Penetapan Kadar Flavonoid Totalnya Harrizul Rivai; Femiwati Femiwati; Krisyanella Krisyanella
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

The study about characterization of water extract of Gynura pseudochina (L.) DC leaves has been done. The study reveals the following non-spesific and specific parameters. It’s water content, density, total ash, insoluble acid ash are 78.69 + 0.21 %; 1.08 + 0.0 %; 3.99 + 0.12%; and 0.67 + 0.10% respectively. It’s bacterial count are 4.4 x 103 colonies/g and 2.3 x 102 colonies/g for fungis count. Gynura pseudochina (L.) DC also known as daun dewa in Indonesia. It has Gynura pseudochina Folium Aqueous Liquidum Extractum as it’s identity. The extract is a liquid extract, with swarthy brown colored, specific smells and tasteless. It’s contains secondary metabolites such as alkaloids, flavonoids, saponins and tannins. The content of compounds soluble in water are 20.25 + 0.53% and soluble in ethanol are 8.59 + 0.79%. The total flavonoids content obtained using spectrophotometry UV-Visible method was 0.07 + 0.01 % w/w.

Penentuan Kadar Beberapa Mineral dan Keasaman Serta Uji Bakteriologi dari Beberapa Air Minum Isi Ulang di Siteba Kota Padang Krisyanella Krisyanella; Yesi Nofrisari; Roslinda Rasyid
Jurnal Farmasi Higea Vol 2, No 2 (2010)
Publisher : STIFARM Padang

The quantitation of some minerals such as iron, zinc, magnese, acidity measurament and bacteriological analysis from same refilling water samples which are collected in Siteba, Padang has been done. Mineral measurement was done by Atomic Absorption Spectroscopy (AAS). Acidy measurement done by acidy meter, and it’s bacteriological analysis done by using MPN (Most Probable Number) method. The result showed iron quantity from sample A, B, and C are 0,0615 mg/L; 0,0745 mg/L; 0,0747 mg/L respectively. It’szink quantity are 0.0110 mg/L; 0.0078 mg/L; 0.0110 mg/L respectively. Its magnese quantity is 0.0228 mg/L; 0 mg/L; 0 mg/L respectively. It’s acidy levels are 6.50; 6.61; 7.00. Its bacteriological number (Escherichia coli) is 5/100 mL; 0/100 mL; 96/100 mL. It showed that sample A and C have not complied the water qualification of public health RI. No. 907/MENKES/SK/VII/2002 in bactriological compounds.

Analisa Protein dan Zat Pengawet (Nitrat dan Nitrit) Dalam Sosis Daging Sapi Siap Saji Roslinda Rasyid; Yuli Anita; Krisyanella Krisyanella
Jurnal Farmasi Higea Vol 2, No 2 (2010)
Publisher : STIFARM Padang

A Qualitative analysis of nitrite and nitrate preservative and analysis of protein content in sausage fast food foundedin some markets in Padang has been done. The preservative in samples were extracted by mixing with water, and then identified by colour reaction. Analysis of preservative in samples was compared with standard preservative substance. From the identification, all samples contain preservative agent, nitrite and nitrate. Micro Kjehdahl method used to analysed protein in samples. The result showed that from each samples contained. Protein content 16.5% for samples A; 17.6% for samples B and 8.31% for samples C.

Isolasi Flavonoid Dari Herba Sida Rhombifolia, Linn. Junuarti Jubahar; Husnal Hayati; Krisyanella Krisyanella
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Flavonoid compounds have been isolated from Sida rhombifolia, Linn herbs. One kilogram of the dried herbs produced 1,7339 g ( 0.17339 % ) congealed extract and 3.87 mg of flavonoid A. Flavonoid A was yellow in colour, amorph solid which was decomposed at 232-234º C. Based on ultraviolet and infrared data and product of its hydrolysis, compound A was Flavonol-3-O-Galaktose.

Uji Aktivitas Sitotoksik Ekstrak Dan Fraksi Dari Spon Laut Petrosia sp. Dengan Metode Brine Shrimp Lethality Test Dian Handayani; Lendra Yunance; Krisyanella Krisyanella
Jurnal Farmasi Higea Vol 3, No 2 (2011)
Publisher : STIFARM Padang

The determination of cytotoxic of the marine sponge Petrosia sp. using Brine Shrimp Lethality Test has been done. The cytotoxic activity analysis were done toward condensed extract, n-hexane, ethyl acetate and butanol fractions and yielded LC50 value 70.736 ppm, 269.153 ppm, 197.38 ppm and 70.667 ppm respectively. It shown that butanol fraction was more cytotoxic than the other fractions.

Aktivitas Perlindungan Sinar UV Ekstrak Etanol Daun Kopi Robusta (Coffea canephora Pierre ex.A. Froehner) Secara In Vitro Krisyanella Krisyanella; Resva Meinisasti
Jurnal Farmasi Higea Vol 14, No 2 (2022)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Kopi merupakan tanaman komoditas utama di Curup Kabupaten Rejang Lebong, Bengkulu. Pemanfaatan spesies kopi umumnya masih terfokus pada biji kopi, sedangkan daun kopi hasil pemangkasan biasanya terbuang. Menurut literatur Daun kopi robusta (Coffea canephora) mengandung senyawa flavonoid dan tanin yang berpotensi memberikan aktifitas tabir surya. Tujuan Penelitian : menentukan nilai SPF dan aktifitas tabir surya dari ekstrak etanol daun kopi robusta. Metodologi penelitian adalah eksperimental laboratorium. Metoda ekstraksi yang digunakan adalah maserasi dengan etanol 70%. Pengukuran nilai SPF dilakukan secara in vitro menggunakan Spektrofotometer UV-Vis. Dari hasil pemeriksaan kandungan metaboblit sekunder, sampel mengandung senyawa Alkaloid, Flavonoid, Saponin, Tanin, Dan Steroid. Senyawa metabolit sekunder golongan flavonoid mempunyai potensi sebagai tabir surya karena adanya gugus kromofor yang mampu menyerap sinar UV sehingga mengurangi intensitasnya pada kulit Tanin juga bermanfaat sebagai tabir surya. Tanin terkondensasi memiliki aktivitas sebagai antioksidan dan dapat melindungi kulit dari kerusakan yang ditimbulkan radiasi ultraviolet. Nilai SPF dari ekstrak dengan konsentrasi 50 ppm, 100 ppm dan 150 ppm yaitu berurut-turut 6,911 (Proteksi sedang); 8,093 (Proteksi maksimum dan 12,989 (Proteksi maksimum). Berdasarkan hasil penelitian terlihat bahwa ekstrak etanol daun kopi robusta memiliki aktifitas tabir surya, dimana peningkatan aktifitas tabir surya berbanding lurus dengan kenaikan konsentrasi ekstrak. Daun kopi robusta berpotensi untuk dikembangkan menjadi sediaan tabir surya

FORMULATION OF HAIR GEL FROM CELERY ETHANOL EXTRACT (APIUM GRAVEOLENS .L) Resva Meinisasti; Krisyanella Krisyanella; Dewi Oktasari
Proceeding B-ICON Vol. 1 No. 1 (2022): Proceeding of The 2nd Bengkulu International Conference on Health (B-ICON 2022)
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/bicon.v1i1.15

Background: Uncontrolled hair loss will cause baldness. Celery (Apium graveolens L.) contains compounds apiin, apigenin, mannitol, inositol, asparagine, glutamine, choline, linamarose potassium and sodium. Apigenin is the main chemical content in celery which is known to have activity as a vasodilator that can stimulate hair growth. The purpose of the study was to determine the hair gel formula that had the best characteristics. The concentration variations used were 5%, 7.5% and 10%. This study uses experimental research methods. The activity starts from the preparation of the ethanol extract of dried celery, gel formualtion, and then evaluation of the preparation. The evaluation of the preparations included organoleptic tests, homogeneity, spreadability, pH, irritation, freeze thraw and the preference of the preparations by the respondents. The results showed that Formulas 1 (5%) and 2 (7.5%) met the standard parameters of hair gel preparations, while formula 3 (10%) did not standardize the spreadability test. In the organoleptic test, it was seen that the higher the concentration of the extract used, the more concentrated the color of the preparation. However, the increase in extract concentration did not significantly affect the dispersion of the preparation. Based on the results obtained, it can be concluded that Formula 1 (5%) has the best hair gel preparation characteristics compared to other formulas.

FORMULATION OF LOTION OF GERGA ORANGE PEEL ETHANOL EXTRACT WITH VARIATION OF EXTRACT CONCENTRATION Krisyanella Krisyanella; Resva Meinisasti; Silvi Elvianita
Proceeding B-ICON Vol. 1 No. 1 (2022): Proceeding of The 2nd Bengkulu International Conference on Health (B-ICON 2022)
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/bicon.v1i1.41

Gerga Orange (Citrus nobilis L. Var. RGL) are the main commodity in Lebong Regency, Bengkulu Province. These oranges have been processed by the community into syrup preparations and from this activity produce waste in the form of fruit peels. Based on previous research, the peel of this citrus fruit is known to have antioxidant and antibacterial activity, so it can be used as a raw material in the manufacture of lotion preparations. The purpose of this study was to determine the characteristics of the three lotion formulations from the ethanolic extract of the gerga orange peel (Citrus nobilis L. Var. RGL) with various concentrations of 8% (F1), 10% (F2), 12% (F3). The method used is the experimental method. The results showed that the three formulations of lotion met the standard of good lotion. In the organoleptic test, there were differences in the color of the preparation, where the color became more concentrated as the concentration of the extract increased. In the homogeneity test, the three formulas showed good homogeneity until the 14th day of testing. The pH of the three formulas was also in accordance with the SNI 16-4399-1996 standard, namely 4.5-8. The three formulas also did not cause allergic reactions to 10 respondents. Based on the results of the research that has been done, it can be concluded that all formulas of the ethanol extract of the gerga orange peel (Citrus nobilis L. Var. RGL) with varying concentrations can be formulated as lotion preparations that are physically and organoleptically stable, as well as the standard of SNI 16-4399-1996 in terms of pH of the preparation and irritation test. Of the three formulas, formula 1 has an advantage over the other formulas because it has a less intense color, which makes it superior in appearance.

Increasing Self-Medication Knowledge of Administrators in the Child Social Welfare Institution Muslim, Zamharira; Susilo, Avrilya Iqoranny; Pudiarifanti, Nadia; Meinisasti, Resva; Krisyanella, Krisyanella; Khasanah, Heti Rais; Irnameria, Dira
Media Karya Kesehatan Vol 6, No 2 (2023): Media Karya Kesehatan
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mkk.v6i2.44731

Child Welfare Institution (CWI) managers often provide self-treatment or self-medication when foster children experience mild symptoms of illness. In its implementation, self-medication often results in inaccuracies. For this reason, it is necessary to increase the self-medication knowledge capacity of CWI managers in Bengkulu City. The aim of this activity is to increase knowledge about self-medication by CWI managers. This activity provides knowledge about how to manage medicines properly and correctly. The training was given using the Active Human Learning Method which was attended by 30 people. Based on the pretest results, the average score was 5.73, while the posttest results showed an increase in the average score to 7.27 and was tested by an independent t-test (p=0.000). Increasing this knowledge is important in supporting rational drug use programs. Keywords: Child Welfare Institutions, knowledge, self-medication.

Co-Authors Akmal Djamaan Andriani Amran Atipah Charunisa Avrilya Iqoranny Susilo Baharyati , Delta Baharyati, Delta Corry Handayani Dachriyanus Dewi Oktasari Dian Handayani Dian Handayani Dinul Aufa Dwi Ramadhani, Wulan Femiwati Femiwati Halimatussadiah, Halimatussadiah Harrizul Rivai Husnal Hayati Irawan, Putra Adi Irnameria, Dira Iskandar, Fadhillah Junuarti Jubahar Khasanah, Heti Rais Khasanah, Heti Rais Lasri Winarsih, Dinda Lendra Yunance Mahrani Napitupulu Meika, Usi Dwi Meinisasti, Meinisasti MENISASTI, RESVA Meri Ardianti Mimi Susanti Muslim, Zamharira Nadeak, Bella Nadeak Nana Susilawati Pudiarifanti, Nadia Putri, Ovie Panca Raden Sunita Rahmanda, Desfi Rais Khasanah, Heti Resva Meinisasti Riyadi, Sunita Rizki Amalia Sari, Rizki Amalia Rizky Yulion Roslinda Rasyid Sagita, Pittri Andriani Salasa, Alfrida Monica Sastri Utami, Mardhah Silvi Elvianita Sunita, Raden Sunita, Raden TUTUT, ADES RELIJEN unance, Lendra Y Utami, Mardhah Sastri Witra Aulia Witra Aulia Yenni Okfrianti Yesi Nofrisari Yuli Anita Zamharira Muslim Zamharira Muslim Zul Amri

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