Article Per Year (5 Year)
p-Index From 2021 - 2026
1.994
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Kesehatan Masyarakat Mulawarman (JKMM) Jurnal Pengabdian Kesehatan Masyarakat Mulawarman Proceeding Mulawarman International Conference on Tropical Public Health Folia Medica Indonesiana
Rahma, Khairunnida
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Other

Published : 13 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 13 Documents
Search

 1   2 
Antifungal Activity of Selaginella plana (Desv. ex Poir.) Hieron Extract Against Candida albicans In Vitro Warella, Juen Carla; Rahma, Khairunnida; Widodo, Agung Dwi Wahyu; Setiabudi, Rebekah Juniati
Folia Medica Indonesiana Vol. 59, No. 3
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Highlights: 1. A study on the medical benefits of Selaginella plana has significant academic value due to its extensive traditional usage among the Moluccan people as a medicinal remedy, especially for its antifungal properties. 2. The findings of this study will allow further screening to determine the mechanism of action of bioactive compounds in inhibiting the growth of Candida albicans Abstract Candidiasis is an opportunistic infection caused by Candida albicans. This infection commonly affects the skin, oral mucosa, vagina, and gastrointestinal tract. Excessive use of azole antifungals in the treatment of Candida albicans infections can lead to the development of resistance. Therefore, it is necessary to explore alternative treatments using medicinal plants such as Selaginella plana, commonly referred to as "rutu-rutu” in a local language spoken across Maluku, Indonesia. Selaginella plana contains active compounds belonging to various chemical classes, including terpenoids, steroids, flavonoids, and saponins. This study aimed to determine the ability of Selaginella plana extract as an antifungal agent against Candida albicans by evaluating its inhibitory and antifungal effects. This study used an actual experimental design and broth dilution method. The research methodology involved the extraction of Selaginella plana using a solvent of 96% ethanol. The extract was then prepared in various concentrations, i.e., 100%, 50%, 25%, 12.5%, 6.25%, and 3.125%. Additionally, ketoconazole and distilled water were included in the experiment for the positive and negative controls, respectively. The results of this study demonstrated that Selaginella plana extract inhibited the growth of Candida albicans when administered starting at a concentration of 12.5%. However, the antifungal potential of Selaginella plana extract that induced cell death was only observed at a concentration of 100%. The fungicidal activity was exclusively identified in the undiluted, pure extract. The inhibitory and cytotoxic effects of Selaginella plana on Candida albicans cells were attributed to the presence of bioactive compounds in Selaginella plana, including flavonoids, tannins, terpenoids, and saponins. These bioactive compounds had the ability to inhibit cell growth by altering membrane permeability, causing mitochondrial dysfunction, and disrupting ergosterol biosynthesis. It can be concluded that Selaginella plana extract can act as a fungistatic agent against the proliferation of Candida albicans.
EVALUATION OF ANTIBACTERIAL ACTIVITY OF <i>Amaranthus spinosus</i> EXTRACT AGAINST <i>Streptococcus mutans</i>: AN IN-VITRO STUDY Nisa, Fakhrun; Warella, Juen Carla; Hursepuny, Valentine; Bension, Johan Bruyif; Rahma, Khairunnida
Folia Medica Indonesiana Vol. 61, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Streptococcus mutans is a component of the normal oral flora that can become a primary pathogen, leading to dental caries and tooth decay. Tooth decay and dental caries are the most common oral health issues worldwide. Treatment of dental caries and tooth decay represents a crucial effort in addressing global health concerns. One alternative treatment the community used to treat dental caries and tooth decay is thorn spinach (Amaranthus spinosus). Thorn spinach leaves contain bioactive compounds with potential antibacterial properties, including flavonoids, tannins, saponins, and alkaloids. This study aimed to evaluate the antibacterial activity of thorn spinach leaf extract at concentrations of 10%, 20%, 40%, 80%, and 100% against S. mutans. This study employed a descriptive observational design, utilizing a laboratory-based experimental approach. The leaves were extracted using the maceration technique, employing methanol and ethyl acetate as the solvents. The results showed that these extracts can inhibit the growth of S. mutans. The inhibition zones were observed for the methanol extract at concentrations of 10% (6.84 ± 5.36), 20% (12.95 ± 0.85), 40% (8.45 ± 1.00), 80% (14.66 ± 4.17), and 100% (4.74 ± 2.88). For the ethyl acetate extract, the mean inhibition zones were at concentrations of 10% (0.08 ± 0.15), 20% (8.71 ± 4.04), 40% (11.99 ± 2.44), 80% (14.79 ± 5.13), and 100% (15.00 ± 3.09). These findings indicated that, among the two types of solvents utilized, ethyl acetate was more effective than methanol, demonstrating the highest inhibitory activity with moderate to strong inhibitory categories.
Edukasi Perawatan Kaki pada Pengidap Diabetes Melitus dalam Mencegah Luka Kaki di Kelurahan Sanga-Sanga Dalamm Kutai Kartanegara Khumaidi, Khumaidi; Syahrun, Syahrun; Sukmana, Mayusef; Metungku, Fanny; Rahma, Khairunnida
Jurnal Pengabdian Kesehatan Masyarakat Mulawarman Vol. 3 No. 2 (2025): Desember 2025
Publisher : Fakultas Kedokteran, Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes mellitus (DM) is a chronic disease that often leads to serious complications such as diabetic foot ulcers if not properly managed. This community service activity aimed to increase knowledge and awareness of diabetic foot care among people with diabetes in Sanga-Sanga Dalam Village, Kutai Kartanegara. The program was carried out on July 23, 2025, through an educational session attended by 40 participants. The intervention included lectures, discussions, and demonstrations on proper foot hygiene, footwear selection, and adherence to treatment. Knowledge was assessed using pretest and posttest questionnaires. The results showed a significant improvement in participants’ knowledge, with an average score increase from 58.5 to 91.1 (32.6%). The findings demonstrate that structured and interactive education effectively enhances self-care abilities and preventive behaviors among diabetic patients. Continuous community-based education is essential to reduce the incidence of diabetic foot ulcers and improve quality of life.
Co-Authors Abdulloh, Tomy Adrian Hefotaven Abelio Dirgusma Dalung, Yohanes Agung Dwi Wahyu Widodo Al Yazid, Naufal Sulthan Anggita Wikaningtyas, Dila Basri, Amalia Bension, Johan Bruyif Bohari, Zalfa Aqilah Dahlan, Galena Humairah De Rozari, Theodorus Sebastian Dewi Puspita A, Fitria Fanny Metungku Farras, Rakha Andhika Fitria Dewi Puspita Anggraeni Grace Simanjuntak, Grace Habibi, Muhammad Dzaki Hajid, Emir Muhammad Hanis Kusumawati Rahayu Hursepuny, Valentine Khumaidi Khumaidi Kinanthi, Kalya Natriswa Putri Lelyana Novitasari, Putri Lutfi Salsabila, Vaya Marwan, Muhammad Arkan Ali Masithoh, Dyah Ayu Dian Arini Mona Zubaidah Muhammad Irfan Nathan, Gregory WilterEmmanuel Nisa', Arroyyani Shofiatun Nisa, Fakhrun Nur Qolbiyah, Fadzilah Pabatta, Elsadai Pakendek, Vincent Christopher Pangaribuan, Basa Rahelyia Pratiningrum, Moriko Pratiwi, Saufa Ayudia Purnama, Shalvira Putri, Amanda Amalya Putri, Vidya Hapsari Qurotu'aini, Jihan Hasna Rachman, Muhammad Awaludin Rahmawati, Elsa Aulia Ramadhan, Muhammad Nasywaan Arshia Ramadhani, Tsabitha Rebekah Setiabudi, Rebekah Retnaningrum, Yuliana Rahmah Shabrina, Maryam Siagian, Loly Rotua Dharmanita Sihotang, Cecilia Florentina Swandari Paramita Syafa'at, Arifin Ilham Syahrun, Syahrun Tambunan, Naomi Christy Natasha Toruan, Vera Madonna Lumban Warella, Juen Carla Wibowo, Raden Ayu Utami Yasmine, Syarifah Saniinah