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All Journal Indonesian Journal of Pharmaceutical Science and Technology Biota Majalah Obat Tradisional Pharmascience JFL : Jurnal Farmasi Lampung JPSCR : Journal of Pharmaceutical Science and Clinical Research Journal of Multidisciplinary Applied Natural Science Jurnal Abdimas Kartika Wijayakusuma Jurnal Inovasi Pembangunan Jurnal Media Pengabdian Kepada Masyarakat (JM-PKM) Jurnal Pengabdian Masyarakat Bangsa
Susanti, Laila
Universitas Tulang Bawang
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Journal : Biota

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Formulation Of Ointment From Extract Combination Of Lemongrass (Cymbopogon nardus L. Rendle), Green Betel Leaf (Piper betle L.) And Natural Zeolite As An Antibacterial Agent Laila Susanti; Subur Widodo; Mashuri Yusuf; Retno Fardila Sari
Biota Vol 6 No 2 (2020): Jurnal Biota 2020
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/10.19109/Biota.v6i2.6363

Abstract

Lemongrass (Cymbopogon nardus L. Rendle) and green betel (Piper betle L.) plants are native to Indonesia. Empirically betel leaf can be used as a wound healer, lemongrass leaves are widely used as medicine for insect bites. On the basis of information obtained from various literatures, in this research has been done formulation of ointment from extract combination of lemongrass, green betel leaf and natural zeolite as antibacterial of Staphylococcus aureus. The use of zeolites based on features has a three-dimensional framework structure that is interconnected so that it has a large surface. Based on these reasons, it is believed that zeolites can increase the activity of active substances in ointments. The formulation of ointment extracts of lemongrass leaves-green betel leaves and zeolites with various dosages are KZ (zeolite control), KE (20% -5%), F1 (10% -6% + zeolite), F2 (20% - 5% + zeolite), F3 (30% -4% + zeolite), F4 (20% -0% + zeolite), F5 (0% -5% + zeolite) with a fixed amount of zeolite (2 gr). Evaluation of ointment preparations including organoleptic test, pH, homogeneity, spreading test and adhesion test showed results that met the requirements. The sample was tested for antibacterial activity with positive control (gentamicin 0.1%) showed that all formulas can provide an inhibition zone against staphylococcus aureus, except KZ. Test results were analyzed using One Way Annova with sig (0,000) <p value (0,050) followed by Tukey's further tests. From this explanation it can be concluded that the formulation of ointment from extract combination of lemongrass leaves, green betel leaves and zeolites has antibacterial agent.
Cream Formulation Of Extract Of Maja Leaves (Crescentia cujete) As An Antimicrobial Against Staphylococcus aureus Siti Nurjanah; Yuli Wahyu Tri Mulyani; Laila Susanti; Samsuar Samsuar; Mashuri Yusuf; Meidaliyantisyah Meidaliyantisyah
Biota Vol 7 No 2 (2021): Jurnal Biota 2021
Publisher : Faculty of Science and Technology Universitas Islam Negeri Raden Fatah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/Biota.v7i2.7070

Abstract

Maja (Crescentia cujete L) is a plant that has medicinal properties for various diseases. Leaves of Maja contain some compounds such which are thought to have the potential to be antibacterial. The purpose of this study was to determine the potential of maja leaf extract in cream dosage form and to prove the presence of Antibacterial activity against Staphylococcus aureus. The cream of Maja leaf extract was made into several formulations; (5, 10, 15 %) The results was the cream of Maja leaf extract was able to inhibit the growth of S. aureus with the largest inhibition zone at a concentration of 15% with an average of 11.52 ± 0.95mm. Cream formulations were evaluated physically; organoleptic was resulting F1 in brownish-green, F2 in brown, and F3 in dark brown. Homogeneity tests show that all formulations were homogeneous. The pH value of all formulations following the cosmetic standard was about 4.5 – 6.5. The standard viscosity value was between 2000 – 4000 cps. The stability test of cream preparations shows no changes in the form of low-temperature storage (4ºC), room temperature, and high temperature (40ºC), so that maja leaf extracts can be formulated in cream preparations and cream formulations
Co-Authors Abdiyati, Santi Asfiyatul Affiana, Maulidya Nur Ananta, Nadia Diaz Anita Setiawati Aprilia, Linda Ayu Resa Aulia Agustina, Aulia Cindya Alfi Dyah Rahmawati Fauzi, Fariha Qalbi Ilmillahi Hartono, Adityo Isbiyantoro Isbiyantoro Isbiyantoro Kholida, Nilna Maya Latifah Megasari Latifah Megasari Lilik Koernia Wahidah Luthfiyah, Yosi M. Wahyu Ariawan Mashuri Yusuf Meidaliyantisyah Meidaliyantisyah Merinda Setyowati Mulia, Niken Ayu Dewanti Mulia, Wanda Natasya Dewanti Munadhah, Ummu Khusna Pratiwi, Inda Putri, Alvina Adelia qurrota aini Rahmania, Nayla Rahmawati, Dyah Retno Fardila Sari Riyanti, Deski Rokiban, Akhmad Sa'adah, Isnawaitus Safitri, Andika Samsuar Samsuar Samsuar Samsuar User Samsuar, Samsuar Septiana Simanjuntak Siti Nurjanah Siti Nurjanah Sivitha, Sivitha Suhartina Suhartina, Suhartina Syaiful Bahri Viogenta, Pratika Wenny Indriasari Widiyastuti, Asih Widodo, Subur Yuli Evadianti, Yuli Yuli Wahyu Tri Mulyani Yuli Wahyu Tri Mulyani