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Aktivitas Antibakteri Rimpang Meistera chinensis terhadap Bakteri Staphylococcus aureus ATCC 25023 dan Eschericia coli ATCC 35218 Secara Difusi Agar Karmilah; Reymon; Daud, Nur Saadah; Badia, Esti; Yodha, Agung Wibawa Mahatva; Setiawan, Muh. Azdar; Tee, Selfyana Austin; Musdalipah
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 8, No 1 (2023): February 2023
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v8i1.5651

Abstract

Meistera chinensis merupakan generasi baru famili Zingiberaceae yang tumbuh di Sulawesi Tenggara. Ekstrak buah mengandung metabolit sekunder seperti flavonoid, terpenoid, alkaloid, steroid, dan tanin yang memiliki efektivitas sebagai antioksidan dan antibakteri. Namun, belum ada laporan tentang antibakteri pada bagian rimpang. Penelitian ini bertujuan untuk mengetahui kandungan metabolit sekunder dan aktivitas antibakteri ekstrak etanol rimpang M. chinensis. Serbuk kering rimpang M. chinensis diekstraksi dengan maserasi menggunakan pelarut etanol 96%. Ekstrak dipekatkan menggunakan rotary vacuum evaporator. Metode analisis aktivitas antibakteri menggunakan difusi agar dengan konsentrasi ekstrak 10%, 20%, 30%, dan kontrol positif (Ciprofloxacin 30µg) terhadap Staphylococcus aureus ACTT 25023 dan Escherichia coli ACTT 35218 selama 24 jam. Hasil penelitian menunjukkan bahwa ekstrak etanol rimpang M. chinensis mengandung flavonoid, saponin, alkaloid, steroid, dan fenol, Ekstrak terbukti menghambat pertumbuhan E. coli dengan diameter zona hambat rata-rata secara berturut-turut pada konsentrasi 10%, 20%, dan 30% sebesar 6,08±1,79; 8,16±0,11 dan  10,57±1,34 mm. Pada S. aureus, zona hambat masing-masing konsentrasi 10%, 20%, dan  30% sebesar 5,02±0,79; 6,01±0,69; 8,03±0,76. Analisis One Way ANOVA menunjukkan perbedaan aktivitas antibakteri yang signifikan antar konsentrasi ekstrak pada E. coli dan S. aureus. Dapat disimpulkan rimpang M. chinensis memiliki aktivitas sebagai antibakteri. 
Antibacterial and antiplaque effects of alpinia monopleura herbal toothpaste against streptococcus mutans Nia Afdilla; Prayoga Ridha Faisal; Musdalipah Musdalipah
Jurnal Ilmiah Kesehatan Sandi Husada Vol. 15 No. 1 (2026): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : LPPM Politeknik Sandi Karsa, South Sulawesi, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiksh.v15i1.249

Abstract

Introduction: Dental caries remains a prevalent global oral health problem primarily associated with Streptococcus mutans colonization and dental plaque accumulation. Increasing concerns about the prolonged use of synthetic antibacterial agents have prompted the exploration of plant-based alternatives. Alpinia monopleura, an endemic plant from Southeast Sulawesi, contains bioactive phytochemicals with reported antimicrobial activity. This study aimed to evaluate the antibacterial activity and antiplaque effectiveness of herbal toothpaste containing A. monopleura extract against S. mutans. Research Methodology: A quasi-experimental, randomized pre-test and post-test design was conducted involving 64 participants, allocated into two groups: F1 (20% A. monopleura extract) and F2 (30% A. monopleura extract). Antibacterial activity was assessed in vitro using the agar diffusion method against Streptococcus mutans (ATCC 25175). Clinical effectiveness was evaluated by measuring the plaque index before and after a 7-day intervention. Data were analyzed using paired and independent t-tests, followed by multivariate linear regression at α = 0.05. Results: The 30% formulation demonstrated stronger antibacterial activity with a mean inhibition zone of 14.92 mm compared to 6.87 mm in the 20% group. Both formulations significantly reduced plaque index scores. In F1, the mean plaque index decreased from 2.19 ± 0.69 to 1.34 ± 0.48 (p < 0.001), while in F2 it decreased from 2.50 ± 0.51 to 1.84 ± 0.37 (p < 0.001). Multivariate analysis confirmed extract concentration as a significant predictor of plaque reduction. Conclusion: Alpinia monopleura-based herbal toothpaste exhibits significant antibacterial activity against S. mutans and effectively reduces dental plaque. The 30% concentration shows superior antimicrobial potency, supporting its potential development as a natural dentifrice alternative for caries prevention.
HABITUS DIGITAL GENERASI MUSLIM MILINEAL DAN IMPLIKASINYA TERHADAP PENDIDIKAN ISLAM Tamsil; Jawahir, Achmad; Aldi Ubaidillah, Muh.; Musdalipah; Setiawan, Aan
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 11 No. 03 (2026): Volume 11 Nomor 03, September 2026 Released
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v11i03.64188

Abstract

ABSTRACT The rapid development of digital tecnologi has shaped the digital habitus of the Muslim millinneal generation, influencing the way they think, interact, learn, dan practice their religion. At the some time, Islamic education is required to adapt to these changes without neglecting Islamic value. Agains this background, this study addresses the following rearch question: (1) how is the digital habitus of the Muslim millinneal generation farmed in the are of digital transformation? (2) what are the inplications of the digital habitus of the Muslim millinneal generation for Islamic education in terms of its opportunities and challenges? and (3) what transformation strategi are needed to realize an Islamic digital habitus in Islamic education?. This study aims to analyze the formation of digital habitus, examine its implications for Islamic eduqation, and formulate the concept of an Islamic digital habitus. A qualitative approarch was emplayed using the library research method. Data were collected for books, jurnal articles, and other relevant scholarly documents and analyzed using descriptive analysis. The findings indicate that the digital habitus of the Muslim millinneal generation has two major implications. First, it creates significant opportunities for strengthening Islamic literacy, technology based learning, digital da’wah, collaborative learning, and expanding access to learning resources.second, it presents challenges, including the spread of misinformation, the degradation of digital ethics, inappropriate online content, and religion information with unclear sources and questionable credibility, therefore, the transformation of Islamic eduqation toward an Islamic digital baitus requires strategies such as strengthening Islamic digital literacy, developing an integrative curriculum, reinforcing the role of eduqations, and promoting critical digital learning media grounded in the values of tawhid, sharia, ethics, and responsibility. This study propses the concept of an Islamic digital habitus as a new paradigm for developing Islamic eduqation that is adaptive to digital transformation while preserving the fundamental value of Islam