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All Journal English Teaching Journal : A Journal of English Literature, Language, and Education JURNAL PENDIDIKAN TAMBUSAI Jurnal Penyuluhan Perikanan dan Kelautan DIDAKTIKA : Jurnal Kependidikan Jurnal Review Pendidikan dan Pengajaran (JRPP) MARLIN : Marine and Fisheries Science Technology Journal Jurnal Pendidikan Tata Boga dan Teknologi AJAD : Jurnal Pengabdian kepada Masyarakat JIPMukjt:Jurnal Ilmu Pendidikan Muhammadiyah Kramat Djati Bussman Journal : Indonesian Journal of Business and Management Bursa : Jurnal Ekonomi dan Bisnis JURNAL MUARA PENDIDIKAN Jurnal Medisains Kesehatan Journal of Islamic Studies INOVASI: Jurnal Ekonomi, Keuangan, dan Manajemen APMa Jurnal Pengabdian Masyarakat AIQU: Journal Multidiscipliner of Science
Maharani, Silvia
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Jurnal Medisains Kesehatan

 1 
Perbandingan Efektivitas Antipiretik Ekstrak Etanol Daun Kapuk dan Daun Kembang Sepatu Pada Mencit Terinduksi Pepton Maharani, Silvia; Abeiasa, M. Saka; Yansen, Fatridha
Jurnal Medisains Kesehatan Vol. 6 No. 1 (2025): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v6i1.525

Abstract

Fever is a physiological response of the body to infection, characterized by an increase in temperature due to the activation of endogenous pyrogens. Herbal plants such as kapok (Ceiba pentandra) and hibiscus (Hibiscus rosa sinensis) are traditionally used as antipyretics due to their active compounds such as flavonoids, tannins, and saponins. This study aims to compare the antipyretic efficacy between ethanol extracts of kapok leaves and hibiscus in mice (Mus musculus) induced with fever using 10% peptone intravenously. The study design was a post-test only control group with 24 white male mice divided into three groups: P1 (negative control, only inducing peptone without treatment), P2 (induced by peptone and given kapok leaf extract 300 mg/kgBW), and P3 (induced by peptone and given hibiscus leaf extract 300 mg/kgBW). Body temperature was measured at 30 to 180 minutes after treatment. The results showed a decrease in average body temperature to 38.1°C at P2 and 36.7°C at P3, while P1's body temperature remained high above 39°C. One-Way ANOVA test showed significant differences between groups (p<0.05). Although both extracts showed significant antipyretic effects, hibiscus extract produced a greater decrease in temperature.
Co-Authors Abeiasa, Muhammad Saka Ade Komariah Agustianti, Andini Ika Anhar Faisal Fanani Ariyani, Fitri Arkhan, Rifky Asep Rohman Astuti - Ayuningtiyas, Aisyah Nilam Dari, Ulan Desmawan, Deris Dina Amelia Dwita, Zalfa Putri Faslia Fathin, Ssangiyang Cameilia fetya, Aura Fiana, Marista Fikri, Riki Ukhtul Fitri Fitri Haerunisa, Dwi Saskia Hafiziani Eka Putri, Hafiziani Eka Hamdi Mayulu Haris, Muhammad Ichsan Hasanah, Andila Nurul Heri Prabowo Ira Setiawati, Ira Irvan Iswandi Ismi Mori Putra, Deka Ivanna, Julia kamila, Tasya safa Khoirunnisa Khoirunnisa Kurniati, Willujeng Ligori, Alfonsius Luh Masdarini Mahardika, Rani Malinda, Tia Maria Ulfa muti'ah, Eva Nayu Nurmalia Ni Wayan Sukerti Ningsih, Rastia Nurfauzi, Dwiky Pratama, M. Bintang Rahayu, Teten Ginanjar Rahmawati, Rahmawati Rina Rina Rohmawati Rohmawati Salsabila, Siti Salwa Satria , Alfi Silalahi, Marly Meani Simanjuntak, Zhekiel Sinaga, Putriana Siti Romlah Suarti Subroto, Desty Endrawati Uli Wildan Nuryanto Yansen, Fatridha Yantoro, Yantoro Yuniarti, Tatty