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All Journal JURNAL KIMIA SAINS DAN APLIKASI Biology, Medicine, & Natural Product Chemistry Jurnal Penelitian Farmasi Indonesia Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JOPS (Journal Of Pharmacy and Science) JSFK (Jurnal Sains Farmasi & Klinis) JURNAL PHOTON Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Jurnal Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian
agistia, nesa
Sekolah Tinggi Ilmu Farmasi Riau
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Formulasi dan Uji Aktifitas Antikutu Kepala (Pediculus humanus capitis) Sediaan Sampo Minyak Sereh Wangi (Citronella oil): Formulation and Test of Anti-Head Lice Activity (Pediculus humanus capitis) Citronella Oil Shampoo Preparation (Citronella oil) nesa agistia; Nofriyanti Nofriyanti; Ratna Sari Dewi
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3578

Abstract

One of the problems that reduce a person's confidence is pediculosis. Natural ingredients used as anti-lice are citronella oil (Citronella oil), citronella oil contains citronellal compounds. This study aims to obtain a shampoo preparation that has anti-head lice activity. Citronella oil is formulated in several concentrations, namely 5% (FI), 7.5% (FII) and 10% (FIII). Evaluation of shampoo preparations included organoleptic examination, pH, homogeneity, foam height, irritation, cleaning power, freeze and thaw and anti-lice activity. Data analysis used the One Way ANOVA statistical test to see the comparison formula against the time of tick death. Based on the evaluation of the preparations, it was found that the shampoo had a thick liquid consistency, white in color, had a distinctive smell of citronella oil and no phase separation, pH 5.62-5.69, homogeneous, good cleaning power test, non-irritating, stable, anti-lice activity test FI = 6.24 minutes, FII = 5.38 minutes, FIII = 3.68 minutes, there was a significant difference (p<0.05) between the formulas on the time of tick death.
Evaluasi Karakteristik Fisik dan Uji Iritasi Akut Dermal Sediaan Losion yang Mengandung Senyawa (E)–1–(2–Hidroksifenil)–3–(4–Metoksifenil)prop–2–en–1–on nesa agistia; Ferdy Firmansyah; Ihsan Ikhtiarudin; Selvi Rahmawati
JURNAL FARMASI DAN MAKANAN Vol 9 No 2 (2026): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i2.7798

Abstract

Chalcones are secondary metabolites belonging to the flavonoid class that exhibit sunscreen activity. The chalcone analog (E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one has the potential to be developed as an active ingredient in sunscreen formulations. In this study, the compound was formulated into an oil-in-water (O/W) lotion at three different active ingredient concentrations, namely F1 (0.1%), F2 (0.3%), and F3 (0.5%). The formulations were subsequently evaluated for their physical properties and acute dermal irritation in vivo using experimental animals. The physical evaluation demonstrated that all lotion formulations were homogeneous, had a pH of 6.90, exhibited an oil-in-water emulsion type, possessed a viscosity of 8,866 cps, showed pseudoplastic thixotropic flow behavior, and had a spreadability of 6.25 cm. Furthermore, no significant changes in the physical properties were observed after 8 weeks of storage. The acute dermal irritation test revealed that all formulations had an irritation index of 0, indicating a very slight irritation response. These findings demonstrate that all lotion formulations met the required quality criteria for lotion preparations and were well tolerated, supporting their potential as safe topical sunscreen formulations.
Co-Authors Adel Zamri Adel Zamri Della Ariska Dita Bina Julianti Habeahan Enda Mora Ferdy Firmansyah Fina Aryani, Fina Gressy Novita Haiyul Fadhli Hansen Nasif Husnawati Husnawati Husni Mukhtar Ihsan Ikhtiarudin Ihsan Ikhtiarudin Jasril Jasril Meiriza Djohari, Meiriza Melzi Octaviani Mira Febrina Muhtadi, Wildan Khairi Musyirna Rahmah Nst Neni Frimayanti Nofriyanti Nofriyanti Nofriyanti Nofriyanti Nofriyanti Putri Qurnia Pratiwi Rahma Dona Ratna Sari Dewi Ratna Sari Dewi Rodhia Ulfa Rosnita Dewi Rahmawati Saryono Saryono Selvi Rahmawati Septi Muharni Sulastri Tria Harlianti Tria Harlianti Wildan Khairi Mukhtadi