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All Journal Indonesian Journal of Cardiology Proceedings of the International Conference on Applied Science and Health Global Health Management Journal Jurnal Teras Kesehatan Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Health Sains Tunas Medika Jurnal Kedokteran & Kesehatan Indonesian Journal of Health Sciences Research and Development (IJHSRD) Jurnal Sehat Indonesia (JUSINDO) KOLONI JI-KES (Jurnal Ilmu Kesehatan)
Witri Pratiwi
Universitas Swadaya Gunung Jati
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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A Case Report of A Life-Threatening Condition: Complete Heart Block Induced By Systemic Lupus Erythematosus Puji Rachmawan, Yogi; Pramudya, Arsha; Pratiwi, Witri; Irnizarifka, Irnizarifka; Imani, Fawzia Haznah Nurul
Jurnal Health Sains Vol. 7 No. 4 (2026): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v7i4.2824

Abstract

Systemic lupus erythematous is often accompanied by complications in the cardiovascular system such as pericarditis, valvular disease, coronary artery disease, but complications in the conduction pathway are rare condition. Conduction system disorders such as complete heart block can cause life-threatening conditions and require immediate treatment. This case report describes a 43-year-old woman who presented with syncope and complete heart block. The patient received high-dose corticosteroid therapy but the complete heart block did not improve so a permanent pacemaker was implanted. This case showed that SLE complications in the cardiovascular system including the cardiac conduction system must be watched out for because it is a life-threatening condition.
Excessive Polypharmacy Among Indonesian Heart Failure Patients: Clinical Correlates and Care Implications Yogi Puji Rachmawan; Witri Pratiwi; Bambang Budi Siswanto
Jurnal Kardiologi Indonesia Vol 47 No 2 (2026): April - June, 2026
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.2138

Abstract

Background: Heart Failure (HF) is a major global health problem that often coexists with multiple chronic comorbidities, requiring complex pharmacotherapy. The use of numerous concurrent medications increases the risk of polypharmacy and excessive polypharmacy, which may lead to adverse drug reactions, drug–drug interactions, poor adherence, and higher healthcare utilization. Despite growing awareness of this issue, evidence on the prevalence and determinants of excessive polypharmacy among Indonesian HF patients remains scarce. Methods: This single-center cross-sectional sub-analysis was derived from a cross-sectional study involving 494 adult HF patients treated at Hasna Medika Cardiovascular Hospital, Cirebon, between January and December 2023. HF diagnosis was confirmed by cardiologists using the European Society of Cardiology (ESC) criteria. Polypharmacy was defined as the use of ≥7 medications, while excessive polypharmacy was defined as ≥10 medications. Clinical and demographic variables were extracted from electronic medical records (EMR). Bivariate analysis was performed using Chi-square or Fisher’s exact tests, followed by multivariate logistic regression to identify independent determinants of excessive polypharmacy. Results: The mean age of participants was 58.1 ± 10.5 years, and 53.4% were male. Overall, 42.5% of patients met the criteria for polypharmacy, and 15.6% (n=77) met the criteria for excessive polypharmacy. The most frequent comorbidities were Coronary Artery Disease (CAD) (80.2%), hypertension (23.1%), and Type 2 Diabetes Mellitus (T2DM, 20.0%). In multivariate analysis, T2DM (Adjusted Odds Ratio [AOR] 17.21, 95% CI 8.39–35.34), Chronic Kidney Disease (CKD) (AOR 5.97, 95% CI 2.37–15.03), Chronic Obstructive Pulmonary Disease (COPD) (AOR 6.64, 95% CI 2.64–16.69), and asthma (AOR 26.32, 95% CI 5.79–119.67) were identified as independent determinants of excessive polypharmacy. The model demonstrated good fit (McFadden pseudo-R² = 0.351; Hosmer–Lemeshow p = 0.62). Conclusion: Excessive medication burden is common among HF patients, particularly among those with metabolic and pulmonary comorbidities. These findings highlight the need for systematic medication review and rational prescribing strategies while recognizing that higher medication counts do not necessarily indicate inappropriate prescribing.
Public Knowledge about Wolbachia-Aedes Technology: A Survey among Cirebon City Residents, Indonesia Herawati Herawati; Witri Pratiwi; Muhammad Hussein Gasem
GHMJ (Global Health Management Journal) Vol. 8 No. 3 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-831220

Abstract

Background: Wolbachia-Aedes technology is one of the innovations in reducing dengue fever incidence in Indonesia. Its implementation may be limited by insufficient public knowledge, as low awareness can reduce community acceptance and participation in Wolbachia-Aedes technology, both of which are essential for the technology’s effectiveness. Aims: To determine the public knowledge about Wolbachia-Aedes technology and the associated factors in Cirebon City residents, Indonesia. Methods: This is an observational study with a cross-sectional approach that was conducted in Cirebon City Health Centers (Puskesmas) between June and July 2024, using a cluster random sampling technique. Cirebon City residents who visited Puskesmas and met the inclusion and exclusion criteria were recruited as samples. Data were collected through self-administered validated questionnaires. Results: There were 600 respondents, consisting of female (68%) who participated in the study. Most of the sample were senior high school graduates (68.2%). The results showed that 39.5% of respondents had poor knowledge, while 51.5% had moderate knowledge and 9% had good knowledge. Age [adjusted OR 1.86 (95%CI 1.32-2.63)] and education level [adjusted OR 2.12 (95%CI 1.38-3.27)] were the factors that related to public knowledge about Wolbachia-Aedes technology in Cirebon City, Indonesia. Conclusion: Most Cirebon City residents had moderate knowledge, with a substantial proportion still having poor knowledge regarding Wolbachia-Aedes technology. Older age and lower education levels were associated with poorer knowledge. The government needs to improve public knowledge about Wolbachia-Aedes technology before implementation through targeted health promotion, particularly for older populations and those with lower education levels.
Hubungan Pengetahuan dengan Sikap Mengenai Implementasi Teknologi Wolbachia-Aedes pada Tenaga Kesehatan Kota Cirebon Tajudin Tajudin; Muhammad Hussein G; Witri Pratiwi
KOLONI Vol. 5 No. 2 (2026): JUNI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i2.973

Abstract

Dengue Hemorrhagic Fever remains a public health problem, particularly in endemic areas of Indonesia where cases continue to increase. Wolbachia-Aedes technology is an innovative vector control strategy with the potential to reduce dengue virus transmission. Healthcare workers play an important role in educating the community and supporting public acceptance of this intervention. This study aimed to determine the relationship between knowledge and attitudes regarding the implementation of Wolbachia-Aedes technology among healthcare workers in Cirebon City. Methods: This was an analytical observational study with a cross-sectional design. The population consisted of healthcare workers at public health centers in Cirebon City, with 126 respondents selected using cluster random sampling. The independent variable was knowledge, while the dependent variable was attitude toward the implementation of Wolbachia-Aedes technology. Data were collected using a validated and reliable questionnaire. Univariate and bivariate analyses were performed, and the Chi-square test was used to assess the relationship between variables. Results: Most respondents had good knowledge, totaling 100 respondents (79.4%), and 76 respondents (60.3%) showed a positive attitude. Bivariate analysis showed a significant relationship between knowledge and attitudes regarding the implementation of Wolbachia-Aedes technology, with p=0.0001 and PR=14.143. Conclusion: Knowledge was significantly associated with healthcare workers’ attitudes toward the implementation of Wolbachia-Aedes technology in Cirebon City. Healthcare workers with better knowledge tended to have more positive attitudes toward the implementation of Wolbachia-Aedes technology.
Co-Authors Ahmad Fariz Malvi Z Zein Alfiana, Dina Alia Hikmayani, Airin amanah amanah Amanah Amanah Amelya Chandra Pitriani Annida P Maharani Arni Annisa Rochmaniah Bambang Budi Siswanto Dewi Sukmawati Dharmansyah, Mohamad Irwan Dina Alfiana Donny Nauphar Donny Nauphar Edial Sanif Eni Suhaeni Fauzah, Shofa Nur Febriyana Intan Aryati Febriyana, Silva Hammada, Ronaa Handayani, Tridaya Putri Harlianti, Lita Helda Helda Herawati Herawati Hery Widijanto Imani, Fawzia Haznah Nurul Irnizarifka Ivanka, Muhammad Nabil Prawira Komala, Ika Kusnandang, Agus Lita Harlianti Maharani, Annida Malvi, Ahmad Fariz Marfuati, Sri Muhammad Hussein G Muhammad Hussein Gasem Mulyaningsih, Ruri Eka Maryam Naufal Nabila Faruq Permana, Irman Pramudya, Arsha Pratisara, Regina Pratiwi, Suci Rahmah Puji Rachmawan, Yogi Qolbi, Zeha Nur Rachmawan, Yogi Puji Rahayu , Intan Dwi Reki, Winarto Ricardi W. Witjaksono Alibasjah Risnandya Primanagara Ronaa Hammada Ruri Eka Maryam Mulyaningsih Satrianugraha, Muhammad Duddy Shidqi, Muhammad Daffa Shofa Nur Fauzah Syakhruddin, Imam Tajudin Tajudin Toipah, Iip Tridaya Putri Handayani Yogi Puji Rachmawan Yundari, Yundari Zaidah, Niklah