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Abadi, Hafizhatul
Institut Kesehatan Helvetia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Journal of Pharmaceutical and Sciences.

 1 
Formulasi sediaan body butter ekstrak etanol bunga rosella (Hibiscus sabdariffa L.) sebagai pelembab kulit Diana, Vivi Eulis; Abadi, Hafizhatul; Andry, Muhammad
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.321

Abstract

Background: Body butter is a semi-solid preparation with the highest fat content, so it is very thick and has a consistency very similar to butter, and has a better ability to nourish the skin than body lotion. In addition, body butter itself is perfect for eliminating reddish lines that usually appear on the skin or commonly called strechmarks. Objective: To test the physical quality stability of the concentration of rosella flower ethanol extract formula (Hibiscus sabdariffa L.) in body butter preparations that have been made. Method: The method used is laboratory experimental. Research includes plant extraction, plant identification, making simplisia, phytochemical screening, making ethanol extract, body butter preparation formulation, and quality stability testing of preparations. The sample used in this study was Rosella Flower (Hibiscus sabdariffa L). The research data was analyzed using the SPSS program, namely the Anova test. Result: Rosella flower ethanol extract (Hibiscus sabdariffa L.) has a semisolid form, homogeneous no coarse particles, with a pH value of the preparation ranging from 6.3-6.4, non-irritating, and can moisturize the skin. But it is not stable with cycling test method storage and stable at room temperature for 4 weeks. The best formula of body butter preparation from ethanol extract of rosella flower (Hibiscus sabdariffa L.) to moisturize the skin is a concentration of 3%. Conclusion: Rosella flower ethanol extract (Hibiscus sabdariffa L.) can be formulated in body butter preparations. It is recommended that future researchers formulate it into other preparations in the same concentration using the same plant from rosella flowers (Hibiscus sabdariffa L.).
Isolasi senyawa flavonoid dari daun bakung (Crinum asiaticum L.) Abadi, Hafizhatul; Rumanti, Ruth Mayana; Andry, Muhammad; Nasution, Muhammad Amin
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.322

Abstract

Introduction Sprains and fractured bones are treated with spider lily leaves (Crinum asiaticum L.). Alkaloids, flavonoids, tannins, steroids, and triterpenoids are among the chemical components found in spider lily leaves. The most significant phytochemicals in plants with wide biological advantages for humans are bioactive flavonoids. The purpose of: The study aimed to isolate flavonoid components from spider lily leaves. Methods: This study was descriptive, using the following steps: plant material collection and preparation, sample processing, simplicia characterization, extract preparation, phytochemical screening, hydrolysis, fractionation, analysis using paper chromatography (KKt), and compound isolation using preparative paper chromatography. The isolates were tested for purity using one-way and two-way KKt, and they were identified using UV-Vis spectrophotometry with a shear reagent. The results: The results of the characterization showed that the water content was 7.21%, the water-soluble extract was 11.21%, the ethanol-soluble extract was 9.23%, the total ash content was 1.99%, and the acid-insoluble ash content was 0.81%. The screening findings indicated the presence of flavonoid chemicals. The KKt analysis results revealed that the best mobile phase was 5% acetic acid with ammonia vapor specks, and the preparative KKt isolation results yielded a single blue isolate, which was then identified by UV-Vis spectrophotometry using a shear reagent, resulting in maximum wavelength absorption (max) at band II of 253nm, presumably identifying the isoflavone group of flavonoids. Conclusion: The conclusion showed the ethyl acetate fraction of spider lily leaves could be separated using paper chromatography and that identification by spectrophotometry UV-Vis using a shear reagent wasolate, which was assumed to be an isoflavone group component.
Co-Authors Adek Chan Diana, Vivi Eulis Eulis, Vivi Faadhilah Yusa Simbolon Gumilar, Roni Ignasia Amaerita Buulolo Jamiati Jamiati Khairani Fitri Khairani, Tetty Noverita Lathi Furrahmi Leny Leny, Leny Linda Hernike Napitupulu Mayang Sari Muhammad Amin Nasution Muhammad Andry Ngete, Ani Florida Nidawah Nidawah Nurjanah, Ayu Pamungkas, Barolym Tri Parhan Parhan Pricella Aqwilla Br Ginting Rani Monalisa Hutagaol Riva Rainiza Zuddin Riva Rainiza Zuddin Rumanti, Ruth Mayana Ruth Mayana Rumanti Septiana, Lilik Sipahutar, Rizki Anjani Siti Fatimah Hanum Siti Netti Ritonga Sundari, Tri Surbakti, Chemayanti Tarigan, Jacub Tetty Noverita Khairani Winata, Hanafis Sastra Yoksan Duha Yudianto, Tri Yusta Suriani Ndruru Zulmai Rani