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All Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kreativitas PKM Manuju : Malahayati Nursing Journal Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Jurnal Kesehatan JFM (Jurnal Farmasi Malahayati) Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan Jurnal Medika Nusantara Jurnal Penelitian Perawat Profesional
Kurniati, Mala
Departemen Imunobiomedik Fakultas Kedokteran Universitas Malahayati
Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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The Association of Genetic and Demographic Factors With Hyperthyroid Status at Dr. H. Abdul Moeloek Regional General Hospital, Bandar Lampung Puteri Aulia Zulham; Mala Kurniati; Govindha Putri; Nita Sahara
Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan (Abdigermas) Vol. 4 No. 2 (2026): Jurnal Ilmiah Pengabdian Kepada Masyarakat Bidang Kesehatan (Abdigermas)
Publisher : CV Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/abdigermas.v4i2.755

Abstract

Background: Hyperthyroidism is an endocrine disorder caused by excessive thyroid hormone production that may lead to severe hypermetabolic complications if left untreated. Genetic predisposition and demographic characteristics are considered important factors associated with hyperthyroidism status.Aims: This study aimed to analyze the association between genetic and demographic factors and hyperthyroidism status among patients at Dr. H. Abdul Moeloek Regional General Hospital, Bandar Lampung.Methods: This quantitative study employed a cross-sectional design involving 55 participants recruited through simple random sampling. Information was obtained using a structured data collection form and patients’ medical records at the internal medicine outpatient clinic of Dr. H. Abdul Moeloek Regional General Hospital. Variables analyzed included family history, age, sex, ethnicity, education, occupation, and socioeconomic status. Statistical analysis was performed using Fisher’s Exact Test and Likelihood Ratio tests with a significance level of p < 0.05.Results: The results showed that genetic factors represented by family history were significantly associated with hyperthyroidism among the study participants (p = 0.003). Significant associations were also found between hyperthyroidism status and age (p = 0.002), sex (p < 0.001), and ethnicity (p < 0.001). In contrast, education level (p = 0.167), occupation (p = 0.579), and socioeconomic status (p = 0.530) were not significantly associated with hyperthyroidism status. Family genogram findings demonstrated the occurrence of hyperthyroidism across one to three generations, indicating possible hereditary susceptibility.Conclusion: Family history, as an indicator of genetic predisposition, and several demographic factors, particularly age, sex, and ethnicity, were associated with hyperthyroidism status among the study participants. These findings highlight the potential value of assessing family history and demographic characteristics to support early detection and preventive strategies. However, the findings should be interpreted cautiously
Co-Authors Ade Maria Ulfa Adrian Rival Djamil Agung Sosiawan Annisa Putri Aris Aris Aryawati, Wayan Beatrice Perangin Angin Budi Wiweko Cerry Herina Friscilla Chintia Risnawati Dedek Aji Pamungkas Devy Kurniasari Dian Agustin Wahjuningrum Dita Fitriani Dita Fitriani Dwi Anita Suryandari Dwi Marlina Dwi Marlina Dwi Marlina Syukri Dwita Canggi Siregar Easter Yanti, Dhiny Eksa, Dwi Robbiardy Fajriani Damhuri Fauzan Hamid Febriani Putri, Devita Febtri Irnawita Fivi Larasathi Fonda Octarianingsih Shariff Gilang Ramadhan Putra Govindha Putri Hasbie, Neno Fitriyani Hernowo Anggoro Intan Putri Permata Hati Liya Agustin Umar Luluk Yunaini Muhammad Taufik Akbar Ni Luh Putu Eka Kartika Sari Nofita Nofita Novitasari Novitasari Nurhalina Sari Panghiyangani, Roselina Pudji Sari Puteri Aulia Zulham RA Norma Estarina Ranowo Usi Angelina Reny Yustika Reva Kusmiati RM Coen Pramono D Sahara, Nita Selvia Anggraeni Selvia Anggraeni Sjahriani, Tessa Syuhada Syuhada Syuhada Syuhada Tusy Triwahyuni Tusy Triwahyuni Upik Pebriyani Upik Pebriyani Vira Saamia Yesi Indriyani Yonanda Adityo Zulhafis Mandala