Claim Missing Document
Check
Articles

EVALUASI SIFAT FISIK SEDIAAN SHAMPO EKSTRAK DAUN KATUK (Sauropus androgynus (L) Merr) DENGAN BERBAGAI VARIASI VISCOSITY AGENT Rashati, Dewi; Eryani, Mikhania Christiningtyas
Jurnal Riset Kefarmasian Indonesia Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v1i1.6

Abstract

Sauropus androgynus (L) Merr leaf in Indonesia called katuk have strong antioxidant activity with IC50 80,01 ppm. The aims of this research is want to know physical properties of katuk leaf shampo which is formulated in various formulas. In this research katuk was formulated in shampoo with viscocity agent (HPMC, sodium CMC and Carbopol) in various concentration. The result showed that all shampoo formulas had low jasmine smell, but had different in form and colour. Shampoo viscocity increased with increased viscocity agent. The highest viscocity showed by F7 with 0,5% carbopol concentration. pH test showed that the shampoo with HPMC and sodium CMC had pH value 6. pH value of shampoo with carbopol was 5. All of pH formulas meet the requirement of SNI standard. Statistical result showed that the physical properties of foam high, viscocity and pH all formulas had significant difference.
Enhancing Photoprotective Performance of Sunscreen Lip Tint Through Factorial Design Optimization of Naringenin and Titanium Dioxide Eryani, Mikhania Christiningtyas; Azizah, Fatiya; Ameliana, Lidya; Sari, Lusia; Ryad Alati
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 11 No. 1 (2026)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v11i1.44130

Abstract

The sun emits various types of radiation, including ultraviolet (UV) radiation, which can damage skin structure, triggering premature aging, irritation, sunburn, and pigmentation disorders. Naringenin and titanium dioxide are known to have protective effects against UV radiation. This study aimed to evaluate the effects of naringenin and titanium dioxide concentrations and their interactions on the physical quality and in vitro sunscreen efficacy of lip tint formulations, and to determine the optimal formulation using Design-Expert software. This study is the first to optimize lip tint sunscreen using factorial design with naringenin and TiO₂.The results showed that the optimal formulation achieved an SPF of 38.23, %TE of 0.0562, and viscosity of 16,166 mPas at 2.1% naringenin and 10% titanium dioxide. Furthermore, higher concentrations of both active ingredients increased the SPF value and decreased the %TE and %TP values. Statistical analysis using a one-sample T-test showed no significant difference between the predicted and experimental results (p > 0.05), confirming the validity of the optimization model.
Potential of Lactic Acid Bacteria From Tape and Jember Tempeh as a Probiotic Candidate Siti Nur Azizah; Mikhania Christiningtyas Eryani; Azizah Azizah
Jurnal Biodjati Vol 6 No 2 (2021): November
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i2.12393

Abstract

Probiotics are microbes in fermented foods that have beneficial effects on health. Microbes that act as probiotics are lactic acid bacteria (LAB) that can produce metabolites such as lactic acid, hydrogen peroxide, and bacteriocins. This study aimed to obtain lactic acid bacterial isolates from tape and tempeh, and to test the potential of LAB as a probiotic candidate by activity test as an antidiarrhea and its resistance to gastric pH and bile salts. The fermentation products used as a source of LAB isolates are tempeh sumber mas merk, and yellow cassava tape, sari madu merk from Jember. The results of the first stage regarding the isolation of LAB using GYP media showed that there were 2 LAB isolates (TaJ.14 and TaJ.15) from the tape and 4 LAB isolates (TeJ.18, TeJ.22, TeJ.24, and TeJ.25) from tempeh. The results of the antidiarrheal test using the disc diffusion method (oxoid) showed that TaJ.14 and TaJ.15 isolates were able to inhibit Bacillus subtilis, Escherichia coli, and Shigella dysentriae, while TeJ.18, TeJ.22, TeJ.24, TeJ.25, and Lactobacillus casei (control) was only able to inhibit B. subtilis and E. coli. The results of LAB resistance to gastric pH showed that the TeJ.25 isolate had the highest percentage of pH 3 and 2.5 resistance (51.13 and 33.03%) compared to other isolates and controls. LAB resistance test results against bile salts (oxgal) showed that the TeJ.22 isolate had the highest percentage of resistance (75.10%) compared to other isolates although was still higher in control (75.99%).