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PENGARUH VARIASI KONSENTRASI HPMC TERHADAP SIFAT FISIK GEL EKSTRAK KULIT PISANG AGUNG SEMERU (Musa paradisiaca L.) Eryani, Mikhania Christiningtyas; Siddiq, Hadi Barru Hakam Fajar; Rashati, Dewi; Safitri, Risma Khoiro
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.320

Abstract

The aims of this study was to determine the effect of HPMC variation concentration to the physical properties of Semeru Agung banana (Musa paradisiaca L.) skin extract gel. Gel was formulated with various HPMC concentration namely F1 (2%), F2 (3%) and F3 (4%). Gel was evaluated organoleptic, homogeinity, pH, viscosity, spreadbility and adhesion value. The results showed that F2 meet the organoleptic requirements while F1 and F3 did not meet. All formulas are homogeneous. The results of the pH test showed that the pH value of F1 was 5.9 ± 0; F2 of 5.8± 0 ; F3 of 5.9 ± 0. The results of the viscosity test showed that the viscosity value of F1 was 150 ± 0 dPas; F2 of 250 ± 0 dPas; F3 of 300 ± 0 dPas. The results of the dispersion test showed that the dispersion value of F1 was 5.6 ± 0.06 cm; F2 of 5.3 ± 0.29 cm ; F3 is 4.0 ± 0.12 cm. The results of the adhesion test showed that the value of the F1 adhesiveness was 11.04 ± 0.43 seconds; F2 of 17.4 ± 1.47 seconds; F3 is 24.2 ± 2.44 seconds. It is known that variations in HPMC concentration affect gel texture, viscosity, spreadability and adhesion, and have no effect on gel smell, color and pH.
EVALUASI SIFAT FISIK SEDIAAN SHAMPO EKSTRAK DAUN KATUK (Sauropus androgynus (L) Merr) DENGAN BERBAGAI VARIASI VISCOSITY AGENT Rashati, Dewi; Eryani, Mikhania Christiningtyas
Jurnal Riset Kefarmasian Indonesia Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v1i1.6

Abstract

Sauropus androgynus (L) Merr leaf in Indonesia called katuk have strong antioxidant activity with IC50 80,01 ppm. The aims of this research is want to know physical properties of katuk leaf shampo which is formulated in various formulas. In this research katuk was formulated in shampoo with viscocity agent (HPMC, sodium CMC and Carbopol) in various concentration. The result showed that all shampoo formulas had low jasmine smell, but had different in form and colour. Shampoo viscocity increased with increased viscocity agent. The highest viscocity showed by F7 with 0,5% carbopol concentration. pH test showed that the shampoo with HPMC and sodium CMC had pH value 6. pH value of shampoo with carbopol was 5. All of pH formulas meet the requirement of SNI standard. Statistical result showed that the physical properties of foam high, viscocity and pH all formulas had significant difference.
Pengembangan Lotion Anti Nyamuk Ekstrak Daun Kenikir (Tagetes erecta L.) Dengan Variasi Konsentrasi Setil Alkohol Eryani, Mikhania Christiningtyas; Rashati, Dewi; Falahi, Asa; Husni, Patihul; Agustin, Eka Yulia
JURNAL FARMASI GALENIKA Vol 13 No 1 (2026): Jurnal Farmasi Galenika Volume 13 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i1.423

Abstract

The use of chemical-based mosquito repellents has excellent repellent power, but their use can cause hypersensitivity and irritation. In Indonesia, there are several plants that contain essential oils and have mosquito repellent effects. One of them is cosmos (Tagetes erecta L). Cosmos leaf extract is formulated into a lotion preparation so that it can adhere to the skin for a longer time, thus providing longer-lasting mosquito repellent properties. This research aims to determine the effect of varying cetyl alcohol concentrations on the physical properties of lotion. There are 3 lotion formulas used with cetyl alcohol concentrations of 2% (F1), 2.5% (F2), and 3% (F3). The research results show that F1 has a thick texture and brownish-yellow color, F2 has a thick texture and green color, and F3 has a very thick texture and green color. All formulas are homogeneous. F1, F2, and F3 had pH values of 7.5±0, 7.5±0, and 7.9±0, respectively. F1, F2, and F3 have respective viscosities of 20±0 dPas, 30±0 dPas, and 35±0 dPas. F1, F2, and F3 had spreadability values of 8.48±0.51 cm, 7.81±0.05 cm, and 7.10±0.37 cm, respectively. The conclusion of this study is that variations in cetyl alcohol concentration affect the texture, color, pH, viscosity, and spreadability of the lotion.
Pengaruh Variasi Konsentrasi Cocamidopropyl Betaine Pada Karakteristik Fisik Sampo Ekstrak Kering Teh Hijau Husni, Patihul; Silviya, Rini; Hasanah, Uswatul; Eryani, Mikhania Christiningtyas; Dewi, Mayang Kusuma; Putriana, Norisca Aliza; Januarti, Melinda
JURNAL FARMASI GALENIKA Vol 13 No 1 (2026): Jurnal Farmasi Galenika Volume 13 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i1.435

Abstract

Hair growth–promoting preparations are used to prevent hair damage problems. Compounds contained in green tea extract have activity as hair growth promoters. This study aimed to obtain data on the effect of variations in cocamidopropyl betaine concentration on the physical characteristics of shampoo containing dry green tea extract. The formulations were prepared in three formulas (F1, F2, and F3) containing different concentrations of cocamidopropyl betaine (8.25%, 8.5%, and 8.75%). The research stages included formulation followed by physical evaluation, including organoleptic properties, homogeneity, pH, viscosity, and foam stability. The results showed that the shampoo preparations were viscous liquids, brown in color, with a characteristic odor, pH of 7–8, viscosity of 250–300 cPs, and foam stability of 15–20 cm. The conclusion of this study is that variations in cocamidopropyl betaine concentration affect the physical characteristics of shampoo containing dry green tea extract. The concentration of cocamidopropyl betaine greatly influences the physical stability of the shampoo, with F3 as the best formula based on physical evaluation, which contains 8.75% cocamidopropyl betaine.
Enhancing Photoprotective Performance of Sunscreen Lip Tint Through Factorial Design Optimization of Naringenin and Titanium Dioxide Eryani, Mikhania Christiningtyas; Azizah, Fatiya; Ameliana, Lidya; Sari, Lusia; Ryad Alati
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 11 No. 1 (2026)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v11i1.44130

Abstract

The sun emits various types of radiation, including ultraviolet (UV) radiation, which can damage skin structure, triggering premature aging, irritation, sunburn, and pigmentation disorders. Naringenin and titanium dioxide are known to have protective effects against UV radiation. This study aimed to evaluate the effects of naringenin and titanium dioxide concentrations and their interactions on the physical quality and in vitro sunscreen efficacy of lip tint formulations, and to determine the optimal formulation using Design-Expert software. This study is the first to optimize lip tint sunscreen using factorial design with naringenin and TiO₂.The results showed that the optimal formulation achieved an SPF of 38.23, %TE of 0.0562, and viscosity of 16,166 mPas at 2.1% naringenin and 10% titanium dioxide. Furthermore, higher concentrations of both active ingredients increased the SPF value and decreased the %TE and %TP values. Statistical analysis using a one-sample T-test showed no significant difference between the predicted and experimental results (p > 0.05), confirming the validity of the optimization model.