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All Journal Jurnal Ilmu Dasar Pharmaciana: Jurnal Kefarmasian Jurnal Florea Acta Pharmaceutica Indonesia Journal of Islamic Pharmacy IDJP (Indonesian Journal of Pharmaceutics) Jurnal Biodjati Jurnal Informasi Kesehatan Indonesia (JIKI) Jurnal Riset Kefarmasian Indonesia Abdimasku : Jurnal Pengabdian Masyarakat Borneo Journal Of Pharmascientech Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Pengabdian UNDIKMA Jurnal Ilmiah Farmasi Akademi Farmasi Jember Journal of Agropharmacy

Eryani, Mikhania Christiningtyas

Akademi Farmasi Jember

Author-ID : 960239

Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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POTENSI STREPTOMYCES ENDOFIT RIMPANG KENCUR DAN DAUN SIRIH MERAH SEBAGAI ANTITUBERKULOSIS PADA MYCOBACTERIUM TUBERCULOSIS GALUR SENSITIF Siti Nur Azizah, Mikhania Cristiningtyas Eryani
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Juli - Vol.3 No.1
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53864/jifakfar.v3i1.38

The objective of this research was to obtain Endophitic Streptomyces from some medical plants which have antituberculosis effect and also to test its antitubercullosis activity againts sensitive stain of Mycobacterium tuberculosis. Medicinal plants used in this study were Kaemferia galanga, Hibiscus sabdariffa and Piper cronatum. Streptomyces was isolated using two different media namely Humic Acid Vitamin (HV) agar and HV with plant extract, and purified on Yeast Malt Agar (YMA) medium. Morphological characterization of Streptomyces obtained was observed including aerial mycelium and substrate mycelium, pigmentation, and colony surface. A total of 5 endophitic Streptomyces genus were obtained from medicinal plant. Isolates K.J3A, K.J3B, K.J4 and K.J11 from Kaemferia galanga radix, S.MJ1 from Piper cronatum folium. Streptomyces was not found from Hibiscus sabdariffa calyx. Each isolate had variety of characteristics which could be seen in aerial mass color, substrate mass color, and pigmentation. Antitubercullosis activity showed that total of 5 endophitic Streptomyces were not capable to inhibit the growth sensitive stain of M. tubercullosis.Keywods: Antituberculosis, endophitic actinomycetes, Kaemferia galanga, Hibiscus sabdariffa

PENGARUH VARIASI KONSENTRASI MINYAK ZAITUN (OLIVE OIL) TERHADAP KELEMBUTAN SABUN CAIR Mikhania Christiningtyas Eryani, Dewi Rashati
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2016: Desember - Vol.1 No.2
Publisher : AKADEMI FARMASI JEMBER

Zaitun tree (Olea europaea) comes from the Middle East and widely grown in Asia. The fruit and oil extraction widely used as food and medicine. The oil derived from olives is known as olive oil. Olive oil can be used for skin emolient. The aims of this study was to determine olive oil variation concentration to liquid soap softness. The soap was made with varying olive oil concentration (20% known as F1, 30% known as F2 and 40% known as F3). True experimental design with The Posttest Only Experiment was used as the study design. Evaluation of the soap including organoleptic test, pH, spesific gravity, free alkali assay, and responden emolient test. Responden emolient test was taken from 20 responden who has given questioner. The data from emolient test study was calculate by Kruskal Wallis test. The organoleptic test result showed that all formula showed liquid green, homogen, and jasmine odor. pH from F1, F2 and F3 were 10,39; 9,75 dan 9,34 respectively. The spesicic gravity from F1, F2 and F3 were 1,648%; 1,441% dan 0,863 % respectively. The free alkali from F1, F2 and F3 were 0,032%; 0,08% dan 0,064% respectively. The responden emolient test showed that F1 was soft, F2 was midle soft and F3 was very soft.Keywords: oilive oil, soap, softness

AKTIVITAS ANTITUBERKULOSIS EKSTRAK KULTUR CAIR Streptomyces ENDOFIT RIMPANG Kaempferia galanga TERHADAP Mycobacterium tuberculosis RESISTEN Siti Nur Azizah, Mikhania Cristiningtyas Eryani
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

The objective of this research was to examine the antituberculosis activity of drug resistant stains using liquid culture extracts Streptomyces Kaempferia galanga rhizomes. The endophytes Streptomyces, there were KJ.3A, KJ3B, KJ.4, and KJ.11. Two resistant strain of Mycocacterium tuberculosis were used, there were HE strain which resistant to isoniazid dan etambutol and SR stainswhich resistant to streptomisin and rifampisin. The liquid culture extracts of Streptomyces endophytes was obtained from centrifugation method by growing Streptomyces colony into YMB media Antituberculosis activity was using Lowen-stein Jensen (LJ) methode after incubation for 8 weeks. The result showed that the four liquid culture extracts Streptomyces endophytes have not been able to inhibit the growth of Mycobacterium tuberculosis in both HE and SR strainsKeywods: Antituberculosis, endofit Streptomyces, resistant M. tuberculosis

PENGARUH VARIASI KONSENTRASI HPMC TERHADAP MUTU FISIK DAN STABILITAS SEDIAAN SHAMPO EKSTRAK ETANOL DAUN KATUK (Sauropus androgynus (L) Merr) Dewi Rashati, Mikhania Christiningtyas Eryani
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2016: Desember - Vol.1 No.2
Publisher : AKADEMI FARMASI JEMBER

The Aims of this study was to determine effect of HPMC concentration variation to etanol extract Sauropus androgynus (L) Merr shampoo physical properties. True experimental laboratories design was used as design study. Shampoo was formulated in three formulation which used HPMC variation consentration were F1 (1%), F2 (2%) , F3 (3%). Shampoo was evaluated physical properties included organoleptic, pH, viscosity, foam forming, and stability test at 6oC, 300C and 40oC. Organoleptic test was observed by visual observation. pH, viscosity, foam forming, and stability test from three formulation were observed by one way anova statistic. The result showed that HPMC concentration variation didn’t influence to physical properties foam forming and pH shampoo but there had influence to physical properties viscosity. All formulation of formulation unstable during 6 weeks storage.Keywords: Shampoo, etanol extract Sauropus androgynus (L) Merr, HPMC

PENGARUH VARIASI SUHU PENYIMPANAN TERHADAP STABILITAS FISIK SUSPENSI AMOXICILLIN Dewi Rashati, Mikhania C.E, Dewi Nisa
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2017: Desember - Vol.2 No.2
Publisher : AKADEMI FARMASI JEMBER

This study aims to investigate effect of variation storage temperature on the physical stability of amoxicillin suspension. The physical stability of the amoxicillin suspension included organoleptic, pH, viscosity and volumes of flocculation and deflocculation sedimentation. The research method used true experimental design method with pre-test and post-test control group design. The sample used amoxicillin suspension with temperature storage variation were cold temperature, room temperature and warm temperature. The results of research data on physical stability of organoleptic were processed compared with the condition before storage. The results of research data on physical stability of pH, viscosity and volume of flocculation sedimentation were analyzed using One Way Annova. From the organoleptic suspension of amoxicillin there is significant difference. Data using SPSS with One Way Anova method. All samples at amoxicillin suspension pH with variation of storage temperature got significance value of p0,05, stability of pH has a difference. Viscosity of amoxicillin suspension with variation of storage temperature, the significance value of p0.05, the viscosity physical stability has a significant difference. In flocculation of amoxicillin suspension with variation of storage temperature, the significance value of p0.05 means flocculation in the has a significant difference. In this study the amoxicillin control suspension and all temperature storage did not occur deflocculation.Keywords: Physical stability, Amoxicillin, Suspension

PENGARUH VARIASI KONSENTRASI GLISERIN TERHADAP SIFAT FISIK OBAT KUMUR EKSTRAK DAUN BELUNTAS (Pluchea indica L.) MIKHANIA CHRISTININGTYAS ERYANI
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Mouthwash is an aqueous solution used as a cleanser to improve oral health, aesthetics, and breath freshness. The purpose of this study was to determine the effect of variation concentration of glycerin in beluntas leaf extract (Pluchea indica L.) on the physical properties of mouthwash. Extraction was using maceration method with 5000 ml of 96% ethanol as a solvent. Beluntas leaf extract mouthwash was made in 3 formulas with different glycerin concentration which were 10% (F1), 15% (F2) and 20% (F3). Evaluation includes organoleptic, pH and viscosity tests. The organoleptic test of the mouthwash on the three formulations was brown in color, tasted slightly sweet and had a distinctive minty smell. pH of three formulas were 6.16 - 6.20. Data processing using One Way Anova showed that there was no effect of glycerin variations concentration to pH of mouthwash but there was an effect of glycerin variations concentration to the viscosity of mouthwash.

PENGARUH VARIASI KONSENTRASI HPMC SEBAGAI GELLING AGENT TERHADAP SIFAT FISIK GEL ANTINYAMUK DAUN KENIKIR (Tagetes erecta L.) Mikhania C.E., Asa Falahi, Dewi Ratna Sari
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

The aim of this research was to understand the influence of HPMC variation concentration to the physical characteristic anti mosquito gel of extract kenikir leaves (Tagetes erecta L.). Pre-experiment the one shot case study was used as the research design. The variation of HPMC concentration were 2%; 2,5% and 3%. The materials used in this research were kenikir leaves extract, propylenglycol, methyl paraben, jasmine oil and aquadest. The result show that the variation concentration of HPMC give influence to physical properties of organoleptic gel (form, colour), pH and viscosity. The variation concentration of HPMC did not influence homogeneity, spreadibility and smell of the gel.Keywords : Kenikir leaves, HPMC, Anti Mosquito Gel.

PERBANDINGAN SIFAT FISIK TABLET SALUT CIPROFLOXACIN 500 MG MEREK GENERIK DAN MEREK DAGANG Mikhania C.E., Dewi rashati, Dadang Putra Mardigantara
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2016: April - Vol.1 No.1
Publisher : AKADEMI FARMASI JEMBER

The aim of this study was to compare physical properties ciprofloxacin 500 mg coated tablet generic and trademark brand. The test include weight uniformity, tablet hardness, tablet friability, and disintegration time test. Descriptive experimental design (the one-shot case study) was used as study design. Samples were taken from three generic brands and three trademarks brand ciprofloxacin 500 mg coated tablets. Samples were produced by different factories and taken by simple random sampling method. The results showed that ciprofloxacin 500 mg coated tablets generic and trademark brand are comparable unless hardness of tablet.Keywords: Ciprofloxacin 500 mg, Physical Properties Tablet, Generic and Trademark Brand

PENGARUH VARIASI KONSENTRASI CMC-Na SEBAGAI VISCOSITY AGENT TERHADAP SIFAT FISIK SHEET MASK GEL EKSTRAK DAUN BIDARA (Ziziphus spina-christi L.) MIKHANIA CHRISTININGTYAS ERYANI
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 1 (2022): MEDFARM: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i1.90

Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi CMC-Na terhadap sifat fisik sheet mask gel ekstrak daun bidara (Ziziphus spina-christi L.). Metode penelitian yang digunakan adalah pre-experimental one shot case study. Bahan pembawa yang digunakan dalam penelitian ini adalah CMC-Na dengan konsentrasi yang berbeda F1 (0,5%), F2 (0,75%), F3 (1%). Bahan aktif yang digunakan dalam penelitian ini adalah ekstrak daun bidara sebagai antioksidan. Pengujian sifat fisik yang dilakukan adalah uji organoleptik, homogenitas, pH, dan viskositas. Hasil uji organoleptis menunjukkan bahwa F1 memiliki warna hitam, bentuk agak kental dan berbau mawar. F2 memiliki warna hijau bentuk agak kental dan berbau mawar. F3 memiliki warna hijau, bentuk kental dan berbau mawar. Hasil uji homogenitas menunjukkan bahwa F1, F2, F3 homogen. Hasil uji pH didapatkan data pH F1 sebesar 5,5 ± 0,1, F2 sebesar 6,233 ± 0,115, dan F3 sebesar 6,336 ± 0,152. Hasil uji statistik pH menggunakan one way anova, menunjukkan bahwa pH pada ketiga formula berbeda bermakna. Hasil uji viskositas didapatkan data F1 sebesar 140 ± 17,320 cps, F2 sebesar 270 ± 0 cps, dan F3 sebesar 650 ± 10 cps. Uji statistik viskositas menggunakan Kruskall Wallis test menunjukkan bahwa viskositas pada ketiga formula berbeda bermakna.

POTENSI MEDIA AGAR PISANG MAS SEBAGAI MEDIA TUMBUH Staphylococcus aureus DAN Aspergillus niger Amaliyah Nurul Hidayah; Ayuk Lestari; Mikhania Christiningtyas Eryani; Siti Nur Azizah
Florea : Jurnal Biologi dan Pembelajarannya Vol 9, No 2 (2022)
Publisher : UNIVERSITAS PGRI MADIUN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/florea.v9i2.14237

The high cost of instant culture media on the market has become the background of research to develop Mas banana (Musa acuminata Colla) Agar as a culture medium for Staphylococcus aureus and Aspergillus niger. Culture media is a mixture of nutrients or food substances needed by microorganisms for their growth. The purpose of this study was to determine the potential of Mas banana Agar (Musa acuminata Colla) at various concentrations of 2%, 4%, 6%, and 8% on the number of Staphylococcus aureus colony and Aspergillus niger micellium diameter. The type of research used was experimental research. The research stages were making Mas banana flour, prepared suspension of Staphylococcus aureus and Aspergillus niger, prepared Mas banana Agar, bacterial culture (spread method) incubated for 24hours at 37Â°C and mold (dot method) were incubated for 7 days at 37Â°C. Based on the results, S. aureus colonies on Mas banana Agar at 2%, 4%, 6% and 8% were 43.67 colonies, 52 colonies, 17.33 colonies and 7.67 colonies respectively. The average of Aspergillus niger mycelium diameter at 2%, 4%, 6% and 8% were 11.43 mm, 12.63 mm, 25.26 mm and 62.33 mm respectively. It can be concluded that Staphylococcus aureus and Aspergillus niger cultures growth on Mas banana Agar (Musa acuminata Colla) at various concentrations of 2%, 4%, 6%, 8%.

Co-Authors AA Sudharmawan, AA Adifa, Wildan Hanifatul Aditama, Agnis Agnis Pondineka Ria Aditama Asa Falahi Ayuk Lestari Azizah Azizah Azizah Azizah Balqis, Aura Inzalna Barikah, Kuni Zu’aimah Choiroh, Afifahtul Claudia Fortunata, Florensia Grace Denok Risky Ayu Paramita Dewi Riskha Nurmalasari Eka Deddy Irawan Fachry Abda El Rahman Faisal Akhmal Muslikh Hadi Barru Hakam Fajar Siddiq Hanif, Mohammad Ainul Fakhruddin Hery Diar Febryanto Kukuh Judy Handojo Kusumawardani, Arine Giovani Lina Winarti Lusia Oktora Ruma Kumala Sari Mardani, Alya Eka Dhyra Maulani, Dyan Muthi'atul, Bannan Muzayanah, Arifatul Nina Wijiani Ningsih, Anita Dwi Rahayu Noer Layla Fitri Ani Patihul Husni Rashati, Dewi Risma Khoiro Safitri Saleh Wikarsa Siti Nur Azizah Siti Nur Azizah, Siti Nur Siti Rohmah Fadilah Soemirtapura, Yeyet Cahyati Suryaningsih, Farida Syuhuriah, Ainin Tanfidz Alishlah, Tanfidz Tasya, Pradiva Julias Viddy Agustian Rosyidi Wahyuni, Ela Wardhani, Firdha Aprillia Wikarsa, Saleh Yeyet Cahyati Soemirtapura Zulvania, Clarissa Najwa

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