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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Jurnal Ilmu Dasar Pharmaciana: Jurnal Kefarmasian Jurnal Florea Acta Pharmaceutica Indonesia Journal of Islamic Pharmacy Science and Technology Indonesia IDJP (Indonesian Journal of Pharmaceutics) Jurnal Biodjati Jurnal Informasi Kesehatan Indonesia (JIKI) Jurnal Riset Kefarmasian Indonesia Abdimasku : Jurnal Pengabdian Masyarakat Borneo Journal Of Pharmascientech Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Pengabdian UNDIKMA Jurnal Ilmiah Farmasi Akademi Farmasi Jember Journal of Agropharmacy Jurnal Farmasi Galenika
Eryani, Mikhania Christiningtyas
Akademi Farmasi Jember
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PENGARUH VARIASI KONSENTRASI GLISERIN SEBAGAI HUMEKTAN TERHADAP SIFAT FISIK SEDIAAN OBAT KUMUR DAUN ASAM JAWA (Tamarindus indica L.) Mikhania Christiningtyas Eryani; Agnis Pondineka Ria Aditama
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 5, No 2 (2022): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53864/jifakfar.v5i2.105

Abstract

Obat kumur adalah cairan yang digunakan untuk membilas rongga mulut dengan tujuan untuk menghilangkan atau menghancurkan bakteri dan menghasilkan efek terapeutik dengan menghilangkan infeksi atau mencegah karies gigi. Daun asam jawa (Tamarindus indica L.) memiliki kandungan senyawa flavonoid dan tanin yang berfungsi sebagai anti bakteri pada rongga mulut. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi gliserin terhadap sifat fisik sediaan obat kumur daun asam jawa. Obat kumur daun asam jawa dibuat dalam 3 formula dengan  konsentrasi gliserin yang berbeda-beda yaitu F1 (10%), F2 (15%), dan F3(20%). Uji sifat fisik yang dilakukan meliputi uji organoleptis, pH, dan viskositas. Hasil penelitian menunjukan bahwa sediaan obat kumur pada ketiga formula memiliki warna kuning, rasa agak manis, dan bau khas mint. pH sediaan F1 sebesar 6,20±0,10, F2 sebesar 6,16±0,15 dan F3 sebesar 6,16±0,20. Viskositas sediaan F1 sebesar 1,47±0,04 cPs, F2 sebesar 1,49±0,04 cPs dan F3 sebesar 1,55±0,01 cPs. Kesimpulan dari penelitian ini adalah variasi konsentrasi gliserin tidak berpengaruh terhadap organoleptis, pH dan viskositas sediaan obat kumur daun asam jawa.
PENGARUH VARIASI KONSENTRASI NATRIUM HIDROKSIDA TERHADAP SIFAT FISIK SEDIAAN SABUN PADAT EKSTRAK DAUN NANGKA (Artocarpus heterophyllus Lam.) Mikhania Christiningtyas Eryani; Hadi Barru Hakam Fajar Siddiq; Asa Falahi; Noer Layla Fitri Ani
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 12 No 1 (2023): MEDFARM: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v12i1.161

Abstract

The aim of this study was to determine the variataion concentration effect of sodium hydroxide (NaOH) on the physical properties of jackfruit leaf extract solid soap (Artocarpus heterophyllus Lam.). The concentration of NaOH used were 2.5% (F1); 5% (F2) and 7.5% (F3). The physical evaluation was carried out in the form of an organoleptic test, homogeneity test, pH test, water content test, and foam height test. The results showed that variations in NaOH concentration had no effect on the organoleptic physical properties (odor, shape, color) and homogeneity of solid soap but had an effect on the physical properties of pH, water content, and foam height of solid soap
PENGARUH VARIASI KONSENTRASI HPMC TERHADAP SIFAT FISIK GEL HAND SANITIZER EKSTRAK DAUN PEPAYA (Carica papaya L.) MIKHANIA CHRISTININGTYAS ERYANI
Jurnal Informasi Kesehatan Indonesia (JIKI) Vol 7 No 1 (2021): Jurnal Informasi Kesehatan Indonesia (JIKI)
Publisher : Politeknik Kesehatan Kemenkes Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/jiki.v7i1.2237

Abstract

Latar Belakang: Salah satu bentuk penyebaran mikroorganisme pada manusia adalah melalui tangan. Hand sanitizer merupakan antiseptik pembersih tangan yang telah umum digunakan oleh masyarakat. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi HPMC terhadap sifat fisik gel hand sanitizer ekstrak daun pepaya. Subjek dan Metode: Gel dibuat dalam 3 formula dengan variasi konsentrasi HPMC sebesar 2% (F1), 2.5% (F2) dan 3% (F3). Bahan yang digunakan dalam penelitian ini adalah HPMC sebagai gelling agent, propilenglikol sebagai pembasah, metilparaben sebagai pengawet, oleum rosae sebagai corigen odoris dan aquades sebagai pelarut. Pengujian yang dilakukan meliputi organoleptis, homogenitas, viskositas, pH dan daya sebar gel. Hasil: Hasil pengujian organoleptis menunjukkan bahwa variasi konsentrasi HPMC memberikan perbedaan pada bentuk gel namun tidak memberikan perbedaan pada bau dan warna gel. Hasil pengujian homogenitas menunjukkan bahwa seluruh sediaan homogen. Hasil pengujian untuk viskositas, pH dan daya sebar seluruh formula memenuhi persyaratan. Hasil pengujian statistik menggunakan One Way Anova menunjukkan nilai signifikansi untuk viskositas adalah 0.000, pH adalah 0.003 dan daya sebar gel adalah 0.634 Keseimpulan: variasi konsentrasi HPMC sebagai gelling agent mempengaruhi bentuk, pH dan viskositas gel namun tidak mempengaruhi bau, warna , homogenitas dan daya sebar gel
FORMULASI DAN UJI STABILITAS GUMMY CANDIES BUAH NAGA (Hylocereus polyrhizus) DENGAN VARIASI KONSENTRASI GELATIN DAN KARAGENAN SEBAGAI GELLING AGENT dewi - Rashati; Mikhania Christiningtyas Eryani
Jurnal Informasi Kesehatan Indonesia (JIKI) Vol 5 No 2 (2019): Jurnal Informasi Kesehatan Indonesia (JIKI)
Publisher : Politeknik Kesehatan Kemenkes Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31290/jiki.v5i2.1434

Abstract

Gummy candies (gummy permen) merupakan permen kunyah semi basah yang terbuat dari gelatin dan karegenan. Tujuan penelitian ini adalah memformulasikan buah naga merah (Hylocereus polyrhizus) ke dalam bentuk gummy candies. Pada penelitian ini digunakan variasi konsentrasi gelatin dan karagenan 750 mg : 250 mg (F1), 500 mg : 500 mg (F2) dan 250 mg : 500 mg (F3). Metode pembuatan yang digunakan adalah metode cetak tuang. Gummy candies diperiksa organoleptis, keseragaman bobot, pH dan stabilitasnya pada suhu sejuk, kamar dan hangat. Berdasarkan hasil penelitian didapatkan organoleptis seluruh formula adalah manis, berwarna coklat bening, dan beraroma tutty fruty. Kekenyalan yang didapatkan adalah sedikit kenyal (F1), kenyal (F2) dan sangat kenyal (F3). Seluruh formula memenuhi persayratan keseragaman bobot. Nilai pH seluruh formula adalah 4. Dari uji stabilitas diketahui bahwa formula yang paling stabil adalah F3 yang disimpan pada suhu sejuk (8 °C – 15 °C)
PENGARUH VARIASI KONSENTRASI SETIL ALKOHOL SEBAGAI EMULSIFYING AGENT PADA SEDIAAN LOTION EKSTRAK LIDAH BUAYA (Aloe vera (L.) Burm. f) Nurmalasari, Dewi Riskha; Mardani, Alya Eka Dhyra; Eryani, Mikhania Christiningtyas
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 12 No 2 (2023): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v12i2.192

Abstract

Lotion is a liquid emulsion consisting of an aqueous phase and an oil phase that is stabilized by an emulsifying agent and contains one or more active ingredients. The use of cetyl alcohol as an emulsifying agent was selected because of its properties as a softener, emulsifier, and absorbing water. Cetyl alcohol can increase the stability of the consistency and improve the texture. This study aims to determine the effect of concentration variations in cetyl alcohol on the physical properties of aloe vera extract lotion. The research design used in this study is a pre-experimental preparation formula lotion that was divided into 3 sample groups with different concentrations of cetyl alcohol, namely (2%), (3%), and (4%). Then the sample will be tested for physical properties including organoleptic tests (color, texture, flavor), pH test, spreadability test, and viscosity test, homogeneity test. The research results showed that variations in cetyl alcohol concentrations affected the physical properties of the preparations organoleptic texture, and viscosity. Lotion preparations do not affect organoleptic color, flavor, pH, and homogeneity. Formulation with concentration variation of 3% cetyl alcohol had good physical properties and met the criteria including organoleptic testing with a milky white color, slightly viscous texture, strong jasmine flower flavor, pH value of 7.16 ± 0.34, spreadability value 6.99cm ± 0.18, viscosity value 31.6 dPas ± 2.88, and homogeneous. Keywords: lotion, cetyl alcohol, Aloe vera
PENGARUH VARIASI KONSENTRASI CMC Na TERHADAP SIFAT FISIK MASKER GEL PEEL OFF VITAMIN C Eryani, Mikhania Christiningtyas; Maulani, Dyan; Ningsih, Anita Dwi Rahayu
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 12 No 2 (2023): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v12i2.239

Abstract

Masker wajah peel off gel merupakan salah satu jenis perawatan kulit wajah yang populer, mudah diaplikasikan dan tidak memberikan efek ketergantungan pada produk. Tujuan penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi Na CMC terhadap sifat fisik masker gel peel off vitamin C. Penelitian ini menggunakan 3 formula dengan variasi konsentrasi CMC Na pada F1 3%, F2 4%, dan F3 5%. Pengujian yang dilakukan meliputi uji organoleptis, homogenitas, viskositas, pH, daya lekat, daya sebar, dan waktu pengeringan. Berdasarkan hasil penelitian dapat disimpulkan bahwa variasi konsentrasi CMC Na mempengaruhi organoleptis bau dan tekstur, viskositas, pH, daya lekat, dispersi, serta waktu pengeringan gel namun tidak berpengaruh terhadap warna dan homogenitas gel.
Synthesis Analgetic-Antiiflammation N-(4t-Buthylbenzoil)-p-Aminophenol by Using MgF2 Catalist Siddiq, Hadi Barru Hakam Fajar; Eryani, Mikhania Christiningtyas; Suryaningsih, Farida
Jurnal ILMU DASAR Vol 19 No 1 (2018)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1208.502 KB) | DOI: 10.19184/jid.v19i1.5380

Abstract

Synthesis of N-(4t-buthylbenzoyl)-p-aminophenol has been done by reacting p-aminophenol and 4-tert- buthylbenzoyl chloride compounds with 1% MgF2 catalyst. N-(4t-buthylbenzoyl)-p- aminophenol as an antiinflamatory analgesic. Products were characterized by organoleptic test, melting point determination, TLC, UV/Vis Spectrophotometry, and infrared spectrophotometry. The results of the organoleptic test showed that N- (4t-butylbenzoyl) -p- aminophenol is powdered, gray and tasteless. Melting point of N-(4t- buthylbenzoyl)-p- aminophenol was 193 – 194 °C. TLC results showed that N-(4t-buthylbenzoyl)-p- aminophenol had two Rf values of 0.73 – 0.76 and 0.89 – 0.91. The results of UV wavelength scanning showed that N- (4t-butylbenzoyl) -p-aminophenol had two peaks at 290 and 294 wavelengths. Yield of N-4t- butylbenzoyl-p-aminophenol was 24.35%. Keywords: N-(4t-buthylbenzoyl)-p-aminophenol, MgF2, catalyst, an antiinflamatory analgesic
Formulasi dan Evaluasi Pasta Gigi Berbahan Cangkang Keong Sawah (Pila ampullaceae) dengan Variasi Konsentrasi HPMC Aditama, Agnis; Adifa, Wildan Hanifatul; Muzayanah, Arifatul; Choiroh, Afifahtul; Kusumawardani, Arine Giovani; Wahyuni, Ela; Tasya, Pradiva Julias; Eryani, Mikhania Christiningtyas; Muslikh, Faisal Akhmal
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 2 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i2.533

Abstract

The rice field snail (Pila ampullaceae) is a member of the gastropod class commonly found in freshwater habitats and possesses a hard shell that protects its soft body. The shell of the rice field snail is known to be rich in CaCO3 compounds. In this study, the shell of the rice field snail is formulated into toothpaste as an abrasive material. Toothpaste is a semi-solid preparation that functions to remove dirt from the surface of teeth and maintain dental health. This study aims to determine the effect of hydroxypropyl methylcellulose (HPMC) concentration on the physical and hedonic properties of toothpaste based on rice field snail shell (Pila ampullaceae). Using a one shot case study design, three toothpaste samples with different HPMC concentrations, namely 3%, 4%, and 5%, were evaluated. The preparation evaluation included various physical property tests, such as organoleptic tests, homogeneity, pH, spreadability, viscosity, and foam height, as well as hedonic tests. The results of the study showed that variations in HPMC concentration affected several physical properties, including odor, spreadability, viscosity, and foam height. Among the three formulas tested, Formula 3 with a 5% HPMC concentration was the most preferred by respondents.
Topical Formulation of Herbal Nanocosmetics for Anti-Aging Husni, Patihul; Eryani, Mikhania Christiningtyas
Indonesian Journal of Pharmaceutics Vol 6, Issue 2, May - August 2024
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v5i2.56857

Abstract

Skin aging is a biological process that involves a decline in skin function. Regarding prevention and inhibition of skin aging, use of cosmetic products is an option to avoid skin aging because it can improve texture and function of skin. Recently, development of a topical formulation of herbal nanocosmetics for anti-aging has grown increasingly popular. This review is aimed to summarize and describe topical formulation of herbal nanocosmetics for anti-aging application. In addition, this review also shows several studies performed by researchers in development of topical formulation of herbal nanocosmetics for anti-aging. The data were collected from published journals in the range of 2011-2023. Study result showed that nanoemulsion, nanostructured lipid carriers (NLC), solid lipid nanoparticles (SLN), niosomes, liposomes, ethosomes, and transfersomes are nanotechnology methods used to prepare herbal nanocosmetics for anti-aging in the cream or gel dosage form. In conclusion, herbal nanocosmetics combine the benefits of herbal extracts with nanotechnology which can be used to enhance the effectiveness of natural ingredients for anti-aging effect. Keywords: topical, herbal, nanocosmetics, anti-aging
Potential of Lactic Acid Bacteria From Tape and Jember Tempeh as a Probiotic Candidate Azizah, Siti Nur; Eryani, Mikhania Christiningtyas; Azizah, Azizah
Jurnal Biodjati Vol 6 No 2 (2021): November
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i2.12393

Abstract

Probiotics are microbes in fermented foods that have beneficial effects on health. Microbes that act as probiotics are lactic acid bacteria (LAB) that can produce metabolites such as lactic acid, hydrogen peroxide, and bacteriocins. This study aimed to obtain lactic acid bacterial isolates from tape and tempeh, and to test the potential of LAB as a probiotic candidate by activity test as an antidiarrhea and its resistance to gastric pH and bile salts. The fermentation products used as a source of LAB isolates are tempeh sumber mas merk, and yellow cassava tape, sari madu merk from Jember. The results of the first stage regarding the isolation of LAB using GYP media showed that there were 2 LAB isolates (TaJ.14 and TaJ.15) from the tape and 4 LAB isolates (TeJ.18, TeJ.22, TeJ.24, and TeJ.25) from tempeh. The results of the antidiarrheal test using the disc diffusion method (oxoid) showed that TaJ.14 and TaJ.15 isolates were able to inhibit Bacillus subtilis, Escherichia coli, and Shigella dysentriae, while TeJ.18, TeJ.22, TeJ.24, TeJ.25, and Lactobacillus casei (control) was only able to inhibit B. subtilis and E. coli. The results of LAB resistance to gastric pH showed that the TeJ.25 isolate had the highest percentage of pH 3 and 2.5 resistance (51.13 and 33.03%) compared to other isolates and controls. LAB resistance test results against bile salts (oxgal) showed that the TeJ.22 isolate had the highest percentage of resistance (75.10%) compared to other isolates although was still higher in control (75.99%).
Co-Authors AA Sudharmawan, AA Adifa, Wildan Hanifatul Aditama, Agnis Agnis Pondineka Ria Aditama Agustin, Eka Yulia Ameliana, Lidya Ardian Baitariza, Ardian Asa Falahi Ayuk Lestari Azizah Azizah Azizah Azizah Azizah, Fatiya Balqis, Aura Inzalna Barikah, Kuni Zu’aimah Budianto, Muhamad Oke Choiroh, Afifahtul Claudia Fortunata, Florensia Grace Denok Risky Ayu Paramita Dewi Riskha Nurmalasari Eka Deddy Irawan Fachry Abda El Rahman Faisal Akhmal Muslikh Hadi Barru Hakam Fajar Siddiq Hanif, Mohammad Ainul Fakhruddin Hery Diar Febryanto Januarti, Melinda Kukuh Judy Handojo Kusumawardani, Arine Giovani Lestari, Tirtawati Putri Lina Winarti Lubis, Maralodia Almira Lusia Oktora Ruma Kumala Sari Mardani, Alya Eka Dhyra Maulani, Dyan MAYANG KUSUMA DEWI, MAYANG KUSUMA Muhammad Asrofi, Muhammad Muthi'atul, Bannan Muzayanah, Arifatul Nina Wijiani Ningsih, Anita Dwi Rahayu Noer Layla Fitri Ani Norisca Aliza Putriana, Norisca Aliza Patihul Husni Permatasari, Lina Putri Rashati, Dewi Risma Khoiro Safitri Ryad Alati Safitri, Risma Khoiro Saleh Wikarsa Sari, Lusia Silviya, Rini Siti Nur Azizah Siti Nur Azizah, Siti Nur Siti Rohmah Fadilah Soemirtapura, Yeyet Cahyati Suryaningsih, Farida Syuhuriah, Ainin Tanfidz Alishlah, Tanfidz Tasya, Pradiva Julias Uswatul Hasanah, Uswatul Viddy Agustian Rosyidi Wahyuni, Ela Wardhani, Firdha Aprillia Wikarsa, Saleh Yeyet Cahyati Soemirtapura Zulvania, Clarissa Najwa