Article Per Year (5 Year)
p-Index From 2020 - 2025
6.423
P-Index
This Author published in this journals
All Journal Journal of Biomedicine and Translational Research PROSIDING SEMINAR KIMIA Jurnal Kimia Mulawarman The Indonesian Biomedical Journal Jurnal Pendidikan Kimia (JPKim) Indonesian Journal of Chemistry Hearty : Jurnal Kesehatan Masyarakat Jurnal Keperawatan dan Fisioterapi (JKF) JURNAL KEBIDANAN KESTRA (JKK) Jurnal Kesmas dan Gizi (JKG) JURNAL FARMASIMED (JFM) Jurnal Indah Sains dan Klinis FORTE JOURNAL CHEDS: Journal of Chemistry, Education, and Science Jurnal Farmanesia Jurnal Multidisiplin Madani (MUDIMA) Formosa Journal of Sustainable Research (FJSR) JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal Pengmas Kestra (JPK) Jurnal ABDIMAS MUTIARA Jurnal Indah Sains dan Klinis
Aritonang, Barita
Institut Kesehatan Medistra Lubuk Pakam
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 52 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 52 Documents
Search

 2   3   4   5   6 
ANTIBACTERIAL ACTIVITY OF TARO LEAVES EXTRACTCOMBINED WITH ZnO AND ORGANO-ZnO AGAINST Staphylococcus aureus Ahmad Hafizullah Ritonga; Imel Santika; Hasni Yaturramadhan Harahap; Barita Aritonang
FORTE JOURNAL Vol 5 No 1 (2025): Edisi Januari 2025
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v5i1.1197

Abstract

Staphylococcus aureus is a pathogenic bacterium commonly associated with serious human infections, leading to various health complications. Zinc oxide (ZnO) is well known for its antibacterial properties, while Organo-ZnO, a modified form of ZnO incorporating organic compounds, exhibits even stronger antibacterial potential. Due to their therapeutic properties, Taro leaves (Colocasia esculenta L.) have a long history of traditional use for treating various ailments, including burns and boils. This study aims to identify the active compounds in taro leaves that function as antibacterial agents and to evaluate the combined antibacterial activity of taro leaf extract with ZnO and Organo-ZnO against Staphylococcus aureus. The research was conducted as a laboratory experiment. Phytochemical screening revealed that the taro leaf extract contains alkaloids, flavonoids, tannins, and saponins, which may contribute to its antibacterial effects. Antibacterial activity tests against Staphylococcus aureus showed inhibition zones of 8.5 mm for taro leaf extract, 8.8 mm for 5% ZnO, and 10 mm for 5% Organo-ZnO. The combination of taro leaf extract with 5% ZnO resulted in an inhibition zone of 9.1 mm, while the combination with 5% Organo-ZnO exhibited the highest inhibition zone of 10.7 mm. These results suggest that the ethanol extract of taro leaves possesses significant antibacterial activity against Staphylococcus aureus, and its effectiveness is further enhanced when combined with ZnO and Organo-ZnO. The combination with Organo-ZnO demonstrates the greatest antibacterial potential, indicating its promise for further development in antibacterial applications.
Butterfly Pea and Roselle Combination Extracts Reduce V-CAM, ICAM, and IL-6 Levels in High Fat Atherogenic Diet Rats Karnirius Harefa; Ahmad Hafizullah Ritonga; Riri Safitri; Barita Aritonang; Rahmad Gurusinga; Irmayani Irmayani; Sri Wulan
The Indonesian Biomedical Journal Vol 16, No 6 (2024)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v16i6.3361

Abstract

BACKGROUND: Atherosclerosis, driven by inflammation and oxidative stress, increases the risk of coronary heart disease (CHD). Flavonoids in butterfly pea and roselle are known for their potent antioxidant and anti-inflammatory properties. While their individual effects on cardiovascular health have been studied, no studies have explored the combined impact on atherosclerosis biomarkers, including vascular cell adhesion molecules (VCAM)-1, intercellular adhesion molecule (ICAM)-1, and interleukin (IL)-6. Therefore, this study was performed to evaluate the synergistic effects of butterfly pea and roselle combination extracts (BPRCE) on these biomarkers.METHODS: A study with a post-test control group design using 36 male white rats was performed. The rats were randomly assigned to 6 groups; 1 group was fed with standard feed, while 5 groups were fed with a high-fat atherogenic diet (HFAD) to create atherosclerosis rat models. The HFAD rats were given either no treatment, sodium carboxymethylcellulose (Na-CMC), 300, 400, or 500 mg/kgBW BPRCE. Serum levels of VCAM-1, ICAM-1, and IL-6 of rats were measured using enzyme-linked immunosorbent assay (ELISA) methods.RESULTS: Increasing doses of BPRCE resulted in a significant reduction in VCAM-1, ICAM-1, and IL-6 compared to the other groups. The group with the highest dose, 500 mg/kgBW BPRCE, showed the greatest reduction of VCAM-1 level (32.73±3.57 pg/mL), ICAM-1 level (5.68±1.17 ng/mL), and IL-6 levels (21.49±4.62 pg/mL).CONCLUSION: Administration of BPRCE in atherosclerosis rats model reduces VCAM-1, ICAM-1, and IL-6 in a dose-dependent manner. This study showed that using BPRCE as a traditional remedy for preventing and treating CHD at an optimal dose of 500 mg/kgBW might be a potential future application in reducing atherosclerosis biomarkers.KEYWORDS: VCAM-1, ICAM-1, IL-6, butterfly pea, rosella, atherosclerosis
EVALUATION OF THE SPEED OF RESPONSE OF PRIMARY HEALTH CARE WORKERS IN HANDLING PATIENTS WITH HYPERTENSION CRISIS Aritonang, Barita
JURNAL KEBIDANAN KESTRA (JKK) Vol. 6 No. 1 (2023): Jurnal Kebidanan Kestra (JKK)
Publisher : Fakultas Kebidanan Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkk.v6i1.2521

Abstract

Hypertensive crisis is an emergency condition that requires rapid treatment to prevent complications such as heart failure, stroke, or other organ damage. The speed of response of health workers in primary care is a crucial factor in handling this condition. The purpose of this study was to evaluate the speed of response of health workers in handling patients with hypertensive crisis and to identify the factors that influence it. Research methods: Quantitative and qualitative approaches. Quantitative data were obtained from patient medical records, while qualitative data were collected through interviews with health workers in primary care facilities. The parameters measured included initial assessment time, diagnosis time, treatment initiation time, and referral time if needed. The results showed that the average initial assessment time was 8 minutes (ideal ?5 minutes), diagnosis time 15 minutes (ideal ?10 minutes), treatment initiation time 12 minutes (ideal ?10 minutes), and referral time 25 minutes (ideal ?20 minutes). Several stages of treatment are still delayed due to limited medical personnel, lack of training, and suboptimal referral systems and standard protocols. Discussion: shows that health workers need further training in recognizing and handling hypertensive crises effectively. Optimizing the triage system and improving referral coordination are also important factors in accelerating treatment. Conclusion: although several aspects of service are quite good, improvements are still needed in the primary health care system so that patients with hypertensive crises receive faster and more appropriate treatment, thereby reducing the risk of complications and mortality.
Challenges and Solutions in the Implementation of Standard Operating Procedures (SOP) for Emergency Services in Community Health Centers (Puskesmas) Aritonang, Barita
JURNAL KEBIDANAN KESTRA (JKK) Vol. 6 No. 2 (2024): Jurnal Kebidanan Kestra (JKK)
Publisher : Fakultas Kebidanan Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkk.v6i2.2543

Abstract

Emergency services at Community Health Centers (Puskesmas) play a crucial role in providing first aid to patients in critical conditions before they are referred to higher-level healthcare facilities. However, the implementation of Standard Operating Procedures (SOP) for emergency services still faces various challenges, such as a lack of understanding among healthcare personnel, limited resources, high workloads, and insufficient coordination with referral hospitals. Therefore, the aim of this study is to identify the main challenges in the implementation of emergency SOPs at Puskesmas and to formulate solutions that can improve their effectiveness. The method used in this research is a descriptive study with a qualitative approach, involving interviews and observations with healthcare workers in several Puskesmas. The results show that the majority of healthcare personnel have not fully understood and optimally applied the SOPs due to a lack of training and simulation. Additionally, the limited availability of medical equipment and healthcare staff has led to delays in handling emergency cases. High workloads also become a key factor influencing adherence to the SOPs. The discussion indicates that to overcome these challenges, regular training and simulations, increased availability of medical equipment and healthcare personnel, as well as stricter monitoring and evaluation systems are necessary. Strengthening coordination with referral hospitals also becomes a strategic step to expedite the patient referral process. In conclusion, with the proper implementation of solutions, the SOPs for emergency services at Puskesmas can be improved, making emergency services more effective and efficient in saving patients' lives
ANALYSIS OF FACTORS RELATED TO MIDWIFE CAREER DEVELOPMENT IN PUSKESMAS PLUS PERBAUNGAN, SERDANG BEDAGAI REGENCY Sari, Yunita; Barita Aritonang; Rahmad Gurusinga
JURNAL KESMAS DAN GIZI (JKG) Vol. 6 No. 1 (2023): Jurnal Kesmas dan Gizi (JKG)
Publisher : Fakultas Kesehatan Masyarakat Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkg.v6i1.1881

Abstract

Performance problems have become a serious problem for any agency at this time, and good performance certainly guarantees good service quality. Therefore, providing training and career development to employees is very important to carry out organizational goals effectively and efficiently. Based on preliminary research at the Perbaungan Plus Health Center, it showed that midwives' career development obstacles were: Inadequate administrative support, poor performance by midwives, and lack of guidance in career development. The purpose of this study was to determine the factors related to the career development of midwives at the Perbaungan Plus Health Center, Serdang Bedagai Regency. The research design used in this research is an analytical survey using a cross-sectional study. The research population consisted entirely of midwives and numbered 43 people using a total-sampling technique with 43 people. Data collection methods include primary data, secondary and tertiary. The data analysis used was univariate and bivariate analysis using the chi-square statistical test. The results showed that employee personality p(0.001), external factors p(0.001), compensation structure p(0.004), and organizational politics p(0.024) are related to the midwife's career development. The relationship between employees and organizations does not depend on the development of the midwifery profession p(0.431). The results of the study concluded that employee personality, external factors, and internal compensation systems and policies are related to midwifery professional development, while employee relations with organizations are related to midwifery professional development, meaning not. It is hoped that the Puskesmas can develop policies that focus on midwives in all aspects, including training in good organizational management and professional responsibility, improving employee welfare and creating a comfortable work environment.
Anti-inflammatory Activity of Clitoria ternatea L. and Hibiscus sabdariffa L. Extract Combination in Reducing VCAM-1 Levels in Atherosclerosis Harefa, Karnirius; Ritonga, Ahmad Hafizullah; Safitri, Riri; Aritonang, Barita
JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) Vol. 7 No. 1 (2024): Jurnal Keperawatan dan Fisioterapi (JKF)
Publisher : Fakultas Keperawatan dan Fisioterapi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkf.v7i1.2300

Abstract

Atherosclerosis occurs when plaque accumulates and hardens within the arterial walls, leading to blood vessel blockages and increasing the risk of coronary heart disease (CHD). The extracts of butterfly pea (Clitoria ternatea L.) and roselle (Hibiscus sabdariffa L.) contain flavonoids that possess strong antioxidant and anti-inflammatory properties. This study aims to assess the effects of the combined extract of butterfly pea and roselle (EKTR) on atherosclerosis biomarkers such as Vascular Cell Adhesion Molecules-1 (VCAM-1), Intercellular Adhesion Molecule-1 (ICAM-1), and Interleukin-6 (IL-6). The research employed a True Experimental Laboratory approach using a Post-Test Control Group Design. The subjects were 36 female Wistar rats (Rattus norvegicus L.), randomly divided into six groups through a Completely Randomized Design (CRD). Data were collected on the levels of VCAM-1, ICAM-1, and IL-6 in the serum of obese white rats, measured using an ELISA photometer. Data analysis was conducted using SPSS version 18, with statistical evaluation performed via one-way ANOVA and Tukey's post hoc test. The results showed that increasing doses of EKTR led to significant reductions in atherosclerosis biomarkers such as VCAM-1, ICAM-1, and IL-6 compared to the positive control and other groups. At a dose of 500 mg/kg BW, group F3 recorded IL-6 levels of 30.49 ± 1.60 ng/mL, VCAM-1 level of 29.42 ± 2.58 ng/mL, and ICAM-1 levels of 28.42 ± 1.72 ng/mL. In conclusion, butterfly pea and roselle, rich in flavonoids with potent antioxidant and anti-inflammatory properties, are effective as traditional remedies for reducing atherosclerosis biomarkers and for preventing and treating coronary heart disease (CHD) at an optimal dose of 500 mg/kg BW.
Formulation of Body Scrub Containing Ethanol Extract of Temulawak Rhizome (Curcuma xanthorrhiza Roxb) as a Skin Moisturizer H, Herlina; Melda Astrika Sianipar; Yaturramadhan Harahap, Hasni; Aritonang, Barita; Yosi Darmirani
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2650

Abstract

A body scrub is a cosmetic formulation intended to exfoliate dead skin cells and enhance skin hydration. One promising natural ingredient for body scrub formulations is the rhizome of Java turmeric (Curcuma xanthorrhiza Roxb.), which contains curcumin, a potent antioxidant known to support skin moisture retention. This study aims to evaluate the moisturizing efficacy of a body scrub formulated with Java turmeric rhizome extract. Methods: The rhizome was extracted through maceration using 96% ethanol and incorporated into body scrub formulations at concentrations of 10%, 15%, and 20%. The formulations were assessed for organoleptic characteristics, homogeneity, pH, spreadability, adhesion, oisturizing effect, and potential skin irritation on human volunteers. A commercial body scrub served as the comparator in a study involving 12 volunteers over four weeks, with applications performed once per week. Results: All Java turmeric body scrub formulations remained physically stable at room temperature and did not induce skin irritation. The physical characteristics of the formulations met standard cosmetic criteria, including consistent appearance, pH range of 6–7, spreadability between 5–7 cm, adhesion time above 4 seconds, and absence of irritation. Moisturizing effectiveness was evaluated using a skin analyzer, and data were statistically analyzed using SPSS. The p-value of 0.046 indicates that there is a significant difference between F1 and the commercial product, while for F2 and F3, there is no significant difference in moisturizing effectiveness between the temulawak formulations and the commercial product.. Among the tested formulations, the body scrub containing 20% Java turmeric extract exhibited the highest moisturizing effect. Conclusion: The body scrub formulated with Java turmeric rhizome extract, particularly at a concentration of 20%, is safe for use and shows potential as a natural moisturizing product comparable to commercial products on the market.
Reduction of BOD, COD, and TSS in Textile Wastewater Using Bentonite Activated Charcoal Adsorbent Aritonang, Barita; Ritonga, Ahmad Hafizullah; Harefa, Karnirius; H, Herlina
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2699

Abstract

Wastewater generated by the textile industry contains a variety of hazardous contaminants, including complex organic compounds, synthetic dyes, surfactants, heavy metals, and critical pollution indicators such as biochemical oxygen demand (BOD), chemical oxygen demand (COD), and total suspended solids (TSS). This study evaluates the efficacy of a dual-adsorbent system comprising hydrochloric acid-activated bentonite and phosphoric acid-activated carbon for the removal of BOD, COD, and TSS from textile effluents. The activation processes significantly altered the physicochemical properties of both adsorbents. The moisture content of activated carbon decreased from 18% to 3.10%, while ash content was reduced from 15% to 3.05%. The iodine number, indicative of adsorption capacity, increased from 650 mg/g to 810 mg/g. Additionally, the fixed carbon content improved from 55% to 80%. Surface characterization via Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM) confirmed substantial structural modifications, which enhanced the adsorption performance of the materials. Application of the combined adsorbent system resulted in substantial pollutant removal efficiencies, with reductions of 70.23% in BOD, 70.11% in COD, and 74.88% in TSS. These findings demonstrate that acid-activated bentonite and phosphoric acid-treated activated carbon represent a promising and efficient adsorptive treatment strategy for the remediation of textile wastewater.
Integration of Pharmaceutical Science in the Education of Healthy and Functional Food Preparation at SMK Negeri Pantai Labu Aritonang, Barita; Harahap, Hasni Yaturramadhan; Syarifuddin, Shofian; Meilani, Debi; Wiratma, Dicky Yuswardi
JURNAL PENGMAS KESTRA (JPK) Vol. 5 No. 1 (2025): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/1p8sw386

Abstract

The modernization of lifestyle among today’s adolescents has led to significant changes in daily consumption patterns. Many teenagers tend to prefer fast food that is high in sugar, salt, and fat, but low in nutritional value. This condition may lead to various long-term health problems if not accompanied by adequate nutritional education and awareness. This community service activity aims to integrate pharmaceutical science concepts into the education of healthy and functional food preparation at SMK Negeri Pantai Labu. The implementation method consisted of several stages: initial observation of students’ knowledge and habits, delivery of interactive educational materials, hands-on practice in preparing functional food products, and evaluation through pre-test and post-test instruments. This activity involved 30 students from the culinary arts department. Evaluation results showed a significant improvement across all aspects: knowledge of healthy food increased from 55.0 to 85.3; understanding of functional food from 47.5 to 82.0; understanding of active compounds from 41.2 to 78.5; food preparation skills from 50.4 to 80.6; and awareness of food safety from 52.8 to 86.7. The average overall improvement reached 67.3%. This community service activity concludes that an educational approach based on pharmaceutical science, when applied through culinary practice, is proven to be effective in enhancing students’ competencies, not only in terms of academic knowledge and health awareness but also in fostering entrepreneurial potential in the field of local food.
Evaluation of the Effectiveness of Risk Management in Addressing Patient Safety Incidents Aritonang, Barita
JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) Vol. 7 No. 2 (2025): Jurnal Keperawatan dan Fisioterapi (JKF)
Publisher : Fakultas Keperawatan dan Fisioterapi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/7cz0f255

Abstract

Background: Patient safety incidents are a serious issue affecting healthcare quality and public trust in hospitals. Effective risk management implementation is crucial to reduce adverse events. Objective: This study aimed to evaluate the effectiveness of risk management in mitigating patient safety incidents at Granmed Hospital, Lubuk Pakam. Methods: The study was conducted from September 2023 to February 2024 using a descriptive quantitative and qualitative approach. Data were collected from 50 healthcare worker respondents via questionnaires, incident report reviews, and in-depth interviews. Results: Findings showed that 78% of respondents believed risk management systems were well implemented, especially in risk identification and analysis stages. However, incident reporting was still low (43%), due to fear of punishment and lack of training. Document analysis revealed a 27% decrease in reported incidents compared to the previous year. Conclusion: Risk management at Granmed Hospital is relatively effective in reducing patient safety incidents. Nevertheless, there is a need to improve the safety culture and develop a more transparent reporting system.
Co-Authors Ahmad Hafizullah Ritonga Asvia Rahayu Cut Masyitah Thaib Cut masyithah Debi Meilani Dicky Yuswardi Wiratma Eka Magareta Sinaga Eka Margareta Sinaga Eka Margareth Erawati, Suci Erdiana Gultom Erdiana Gultom Erdiana Gultom Erdiana Gultom Erdiana Gultom Gultom, Erdiana Gusliani Eka Putri Harahap, Hasni Yaturramadhan Hasni Yaturramadhan Harahap Hendri Faisal Herlina Herlina . Herlina H Hermansyah Aziz Hestina . Hestina Hestina Hestina Hestina Hestina, Hestina Imel Santika Irmayani Irmayani Irmayani Irmayani Karnirius Harefa Karnirius Harefa Khairiah, Khairiah Lenny Novita Liver Iman Putra Zai Mala Sari, Nur Melda Astrika Sianipar Munthe, Novita Br Ginting Nova Florentina Nova Florentina Nova Florentina Ambarwati Novesar Jamarun Panjaitan, Delita Pitriani, Pitriani Rahmad Gurusinga Rahmad Gurusinga Rahmad Gurusinga RAMAWATI, NURVITA Riah Ukur Ginting, Riah Ukur Rima Anggeraini Riri Safitri Rotua Sumihar Sitorus Safitri, Riri Salomo Sijabat Siagian, Ernita Siahaan, Enzo W.B Sinaga, Eka M Sinaga, Evi Yuni Sintia Sinaga, Sri Lestari Sitepu, Rahmadani Sitorus, Elly Sri Ulina Sri Wulan Sri Wulan, Sri Suarnikan Hulu Supartiningsih - - Syarifuddin, Shofian Syukri Arief Tamrin Tamrin Widyaningsih, Fadlilah Yanti, Rahma Yaturramadhan Harahap, Hasni Yosi Darmirani Yossy Silalahi Yulidar Laila Safitri Yunita Sari