cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Beny Irawan
Contact Email
benyirawan77@gmail.com
Phone
-
Journal Mail Official
benyirawan77@gmail.com
Editorial Address
-
Location
Kab. deli serdang,
Sumatera utara
INDONESIA
JURNAL FARMASIMED (JFM)
Published by Institut Kesehatan Medistra Lubuk Pakam
ISSN : -     EISSN : 26550814     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Jurnal FARMASIMED (JFM) Volume I Nomor 1 Periode Mei - Oktober Tahun 2018. Jurnal ini memberikan ruang bagi akademisi, peneliti dan pengguna hasil penelitian dan pengabdian untuk mendiseminasikan, menginformasikan, mendiskusikan dan menggunakan hasil penelitian dan pengabdian sebagai upaya meningkatkan kualitas kebijakan di bidang farmasi yang berbasis ilmiah dan dapat dipertanggung jawabkan. Jurnal ini menyajikan hasil penelitian, pengabdian masyarakat serta artikel ilmiah di bidang farmasi.
Arjuna Subject : -
Articles 237 Documents
 8   9   10   11   12 
IDENTIFICATION OF PORK'S CYTOCHROME B GEN IN PROCESSED MEAT NUGGETS IN SUKABUMI VILLAGE, BUAY BAHUGA SUB-DISTRICT USING THE POLYMERASE CHAIN ??REACTION (PCR) METHOD Setiawati, Diah Ayu; Marpaung, Mauritz Pandapotan; Setiawansyah, Arif
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1470

Abstract

Nugget adalah jenis olahan daging restrukturisasi yang sangat rentan terhadap cemaran daging lainnya sehingga mempengaruhi kehalalan suatu produk makanan. Penelitian ini bertujuan untuk mengidentifikasi cemaran sitokrom b pada nugget yang beredar di Desa Sukabumi dengan menggunakan metode Polymerase Chain Reaction (PCR). Sebanyak 3 buah sampel nugget di desa Sukabumi diambil dari produsen yang berbeda dan divisualisasi dengan elektroforesis gel agarose 0,75%, dan divisualisasikan dengan alat documentation system. Hasil penelitian menunjukkan berupa pita-pita marker DNA ledder yang masing-masing berjarak 100 bp. Untuk kontrol positif yang digunakan daging babi dengan marker 130 bp. Kesimpulan dari penelitian ini adalah seluruh sampel tidak terindentifikasi adanya gen sitokrom b.
TESTING OF THE EFFECTS OF BALAKACIDA (CHROMOLAENA ODORATA L.) LEAF EXTRACT OINTMENT ON WOUND HEALING IN GUINEA PIGS Rosa, Vani Silvia; Hasanah, Fenny; Siahaan, Desy Natalia
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1530

Abstract

Kulit ialah area terbesar tubuh yang berguna untuk melindungi tubuh dari bahaya kimia dan fisik seperti goresan, luka yang terinfeksi, dan luka bakar. Luka yakni hilangnya atau rusaknya beberapa jaringan tubuh. Daun balakacida (Chromolaena odorata L.) memiliki getah dan air yang berkhasiat menyembuhkan luka, dapat menghentikan pendarahan pada luka dan lecet dengan cukup cepat. Metode pada penelitian ini yakni eksperimental. Pembuatan ekstrak etanol daun balakacida didapat melalui maserasi dengan pelarut etanol, selanjutnya diformulasikan pada salep dengan ekstrak etanol daun balakacida pada berbagai konsentrasi 5%,7,5%,10%, selanjutnya dilakukan perbandingan dengan kontrol positif (Betadine) serta kontrol negatif (Basis salep). Hasil skrining yang didapat menyatakan ekstrak etanol daun balakacida mengandung senyawa tanin, flavonoid, saponin, alkoloid serta triterpenoid/steroid. Hasil penelitian yang diperoleh sediaan salep ekstrak etanol daun balakacida dengan konsentrasi 5%,7,5%, serta 10% mampu menyembuhkan luka sayat pada marmut. Semua konsentrasi telah menunjukkan kemampuan menyembuhkan luka sayat. Ekstrak etanol daun balakacidayang memberikan efek terbaik pada penyembuhan luka yakni konsentrasi 10%.
TEST OF EFFECT KEDONDONG LEAF ETHANOL EXTRACT (SPONDIAS DULCIS) ON STAPHYLOCOCCUS AUREUS BACTERIA Situmorang, Novidawati Boru; Fatima, Nurdilla; Teresia Marbun, Romauli Anna; Sihombing, Yanna Rotua
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1541

Abstract

Bacteria that cause infection and disease are commonly found in our environment, one of which is Staphylococcus aureus bacteria. Several infectious diseases are also caused by Staphylococcus aureus, including cellulitis, acne (acne), and infection with Staphylococcal Scalded Skin Syndrome (SSSS). To determine whether the ethanol extract of kedondong leaves (EEDK) has antibacterial activity against Staphylococcus aureus bacteria. This study used a laboratory experimental method with several stages such as sample collection, identification of plants for making simplicia, phytochemical screening, extract preparation and preparation of kedondong leaf extract test solutions with various concentrations of 15%, 25%, 35% and positive control (Chloramphenicol), negative control (DMSO), and antibacterial activity testing using the paper disc method. The results of phytochemical screening of kedondong leaf simplicia (Spondias dulcis) found that kedondong leaves contain secondary metabolites such as alkaloids, flavonoids, tannins and saponins that have the potential to inhibit bacterial growth. % of 9.4 mm, 25% concentration of 13.5 mm and the greatest inhibition was at a concentration of 35% of 19.5 mm. Kedondong leaf extract has antibacterial activity against the growth of Staphylococcus aureus bacteria, with moderate to strong categories. inhibit the activity of Staphylococcus aureus bacteria is a concentration of 35%. Based on the description above, it was found that the EED with a concentration of 35% had the greatest antibacterial effect compared to the concentration of 15% and 25%. and it can be concluded that the higher the concentration of the extract used, the higher the antibacterial effect.
ETHANOL EXTRACT LIQUID SOAP FORMULATION LEAVES OF CELERY (Apium graveolens L.) AGAINST Escherichia coli BACTERIA Irwanto, Reno; Apriani Girsang, Santa Dewi; Maria Ginting, Wira; Novia, Reni
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1584

Abstract

Dirty hands will be a source of disease. Soap is a pharmaceutical preparation used to maintain health. Celery (Apium graveolens L.) is a plant of the Apiaceae tribe with a distinctive menthol aroma. This study aimed to determine the inhibitory power of celery leaf extract formulation (Apium graveolens L.) as an antibacterial hand-washing soap. This research method is a type of experimental research. The stages of the research were collecting samples, identifying plants, making simplicia, characterizing simplicia, screening phytochemicals, making extracts and making hand soap formulations of celery leaf extract (Apium graveolens L) at concentrations of 5%, 10%, 15% and antibacterial testing of celery leaves, against Escherichia coli bacteria. The results showed the celery leaf extract soap formulation contained phytochemical compounds of flavonoids, tannins and saponins. The organoleptic test found that the best soap formulation was the F2 formulation with a concentration of 10% at an average level of preference value, namely 3.67 for colour, 3.27 for aroma, and 3.80 for texture. The homogeneity test performed showed that all formulations produced soap with good homogeneity. The height and stability test of the resulting celery extract soap foam ranged from 61-71 mm. The irritation test of the resulting celery extract soap also showed no irritation for all the formulations. The value of the antibacterial activity test found that the F1 formulation showed antibacterial activity with an inhibition zone diameter of 3 (weak), F2 with an inhibition zone of 9 (moderate) and F3 with the antibacterial activity of 12 (strong).
ANTIDIABETIC ACTIVITY TEST OF ETHANOL EXTRACT BROCOLI (BRASSICA OLERACEA VAR. ITALICA) IN WHITE MALE RATS Purba, Novandi; Handayani, Diah Tri; Cahayani Zebua, Kristian; Harefa, Karnirius
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1587

Abstract

Diabetes is a chronic disease characterized by excessive blood glucose levels caused by absolute and relative insulin deficiency. The stages in this study were sampling, identification of samples/plants, simplification, simplification screening, and preparation of extracts by maceration. The method used in the diabetes activity test uses a glucometer to induce alloxan in rats at a dose of 150 mg/kg body weight. The test animals were 25 rats which were divided into 5 treatment groups namely CMC Na 0.5% (negative control), glibenclamide (positive control) 0.45 mg/kg body weight and EEB dose 200 mg/kg body weight, 400 mg/kg body weight and 600. mg/kg body weight. kg B.W. kg body weight as a test material given orally. Measurement of blood glucose values ??according to Allox and on days 3, 5, and 7 after administration of the test substance, namely EEB. The test results data were analyzed statistically using one-way ANOVA at a 95% confidence level followed by Tukey's post hoc test. The results of the phytochemical screening showed that EEB contains alkaloids, flavonoids, tannins, saponins, and glycosides. The results of the diabetes efficacy test showed that EEB doses of 200, 400, and 600 mg/kg BW had an anti-diabetic effect on male white rats. The EEB dose of 600 mg/kg is the most effective. Post hoc Tukey test results showed that EEB doses of 200 mg/kg, 400 mg/kg, and 600 mg/kg were not significantly different from the positive control glibenclamide 0.45 mg/kg (p>0.05) and 200,400 ug. and 600 mg/kg BW were significantly different from the negative control CMC Na 0.5% (p<0.05).
EVALUATION OF THE USE OF ANTIHYPERTENSION DRUG IN HYPERTENSION PATIENTS AT THE GRANDMED LUBUK PAKAM HOSPITAL INSTALLATION IN 2022 Kartika, Dewi; ., Suprianto; Atika, Nur
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1613

Abstract

Hypertension is a condition where there is an increase in blood pressure that exceeds the normal limit, namely systolic blood pressure of more than 140 mmHg and diastolic blood pressure of more than 90 mmHg. Most women suffer from hypertension because of the hormone estrogen. Patients with hypertension who are not given proper therapy will cause complications that can worsen the condition of hypertension. The higher the prevalence of hypertension sufferers, the use of antihypertensive drugs will increase. This will increase the risk of irrational use of antihypertensive drugs. The purpose of this study was to evaluate the rationality of the use of antihypertensive drugs in the Inpatient Installation of Grandmed Lubuk Pakam Hospital based on the right patient, the right indication, the right drug and the right dose. This research is a type of descriptive research. Data collection was carried out retrospectively by using past data in the form of medical records of hypertension patients for the period January 2021 – February 2022 which met the exclusion and inclusion criteria. The sampling technique used was the purposive sampling technique. The results of this study indicate that the most widely used antihypertensive drugs are combination therapy with Calcium Channel Blokers (CCB) + Angiotensin Converting Enzyme Inhibitors (ACEI) (30,6%); Calcium Channel Blokers (CCB) sebanyak (11%); Calcium Channel Blokers (CCB) + Angiotensin Converting Enzyme Inhibitors (ACEI) + Diuretik sebanyak (11,1%); while the low class of drugs is Calcium Channel Blokers (CCB) + Angiotensin Converting Enzyme Inhibitors (ARB) + Angiotensin Converting Enzyme Inhibitors (ACEI); and diuretics + Angiotensin Converting Enzyme Inhibitors (ACEI) were used (2,8%). The results showed that the rationality of the use of antihypertensive drugs obtained was that the patient was correct 100%, the indication was 100%, the drug was 97,2%, and the dose was 97,2%.
EVALUATION OF DRUG INFORMATION SERVICES IN PATIENTS WITH DIABETES MELLITUS IN OUTPATIENT INSTALLATIONS GENERAL HOSPITAL PHARMACY COAL REGION S, Aminah .; M. Br Turnip, Nur Ulina; ., Mahliza
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1636

Abstract

Based on people's unhealthy lifestyle habits and from data on the five biggest diseases for the period July – September 2022 which shows that diabetes mellitus occupies the second level of the five biggest diseases in Batu Bara Hospital, and drug information services are very necessary because there are many patients who still do not understand what to do about drugs, this is done to minimize abuse and interactions between drugs that are not wanted by patients. To find out how drug information services are for DM patients at the Batu Bara Hospital pharmacy installation on an outpatient basis, and to identify the completeness of the information provided by pharmaceutical staff to patients at the Framing Installation at the Batu Bara General Hospital, and also to find out the problems found in technical drug information services provided to patients at the Batu Bara Regional Hospital Pharmacy Installation. This type of research is an observational study. The design of this study is qualitative by making direct observations or observations, interviews and documentation. Drug information services for diabetes mellitus patients in outpatient care at the Batu Bara Hospital pharmacy installation were in the very good category with a result of 96%. Drug information services performed by eight pharmacists consisting of six pharmacists and two pharmacy technicians for outpatient diabetes mellitus patients at the Batu Bara Hospital pharmaceutical installation have met the standards in the very good category with a yield of 96%.
ACTIVITY TESTS OF ANTIBACTERIAL CREAM OF BAY LEAF (Syzygium polyanthum) ETHANOL EXTRACT AGAINST BACTERIA Propionibacterium acnes Octora, Debi Dinha; Sari, Delima
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1659

Abstract

Bay leaf (Syzygium polyanthum) is a plant that is widely used as a flavor enhancer. Based on research that has been done, bay leaves contain flavonoids, alkaloids, tannins, and saponins that have the ability to act as natural antibacterial agents. Improper use of antibiotics in the treatment of infections can cause resistance, so it is necessary to use antibiotics from natural ingredients that have an optimal working power and are relatively safe. P. acnes is one type of bacteria that can cause acne. The purpose of this research is to find out the effective antibacterial activity of bay leaf ethanol extract cream preparation against P. acnes bacteria. This research is an experimental research with 3 different concentration variations. The research results show that there is antibacterial activity at each concentration with an average diameter of the clear zone of 10.06 mm, 14.4 mm and 20.16 mm, the higher the concentration of EEDS, the higher the inhibitory power against P. acnes bacteria growth. The conclusion of the activity of salam leaves with a concentration of 5%, 10%, and 15% provides the most effective inhibition of bacterial growth with a concentration of 10%, 15% which is included in the strong category. Suggestions are expected to the next researcher to be able to test other bacteria and make a greater concentration than the previous research from EEDS.
ANTIBACTERIAL TEST OF ETHANOLIC EXTRACT NANOPARTICLES FROM ARUM MANIS MANGO LEAVES (MANGIFERA INDICA L. VAR. ARUM MANIS) AGAINST STAPHYLOCOCCUS AUREUS Lubis, Nadya Frestika; Rahayu, Yayuk Putri; Nasution, Haris Munandar; Lubis, Minda Sari
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1687

Abstract

Secondary metabolites with antibacterial properties have been found in arummanis mango leaves. Alkaloids, flavonoids, tannins, saponins, triterpenoids, and steroids, especially the mangiferin molecule found in several mango varieties, are also present in arum manis mango leaf extract. Mangiferin has shown action on Staphylococcus aureus as an antibacterial agent that can prevent the development of bacteria. Staphylococcus aureus is one of the bacteria that triggers skin infections. In this research, extract nanoparticles and inhibition tests against staphylococcus aureus bacteria were prepared using extract nanoparticles and ethanol extract of arum manis mango leaves. The manufacture of nanoparticles in this study was carried out because smaller and nanometer-sized materials have more special chemical and glass characteristics; their small size has a greater surface area to volume ratio than larger particles. Nanoparticles are small particles ranging in size from 1 to 1000 nm. A particle size analyzer is used to characterize nanoparticles. Using the disc diffusion method, antibacterial activity tests were carried out at concentrations of 25%, 50%, and 75%, using nanoparticle extracts, and 2.5%, 5%, and 7.5% for extract concentration. The results of the extract nanoparticle size characterization were 40.2 nm. The bacterial inhibition zones of arum manis mango leaf extract obtained at concentrations of 25%, 50%, and 75% were 11.9, 14.4, and 15.4 mm, respectively. Meanwhile, the inhibition zones of nanoparticle bacteria extract 2.5%, 5%, and 7.5% were 15.5, 17.5, and 18.3 mm, respectively. The concentration of 2.5% nanoparticle extract has the inhibition power of bacteria equivalent to that of 75% ethanol extract, so it says that the nanoparticles can reduce the size dose and have an inhibition power in the moderate sensitivity category.
MORINGA LEAF (Moringa Oleifera L.) ETHANOL EXTRACT CLAY MASK FORMULATION AS ANTI-AGING Nurussakinah, Nurussakinah; Fhitriana, Suzan; Khairani, Tetty Noverita; Utari, Sri
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1193

Abstract

Aging is a human physical change caused by age, psychological, and social factors, especially on the face, neck, upper arms and hands. Aging is unavoidable and goes at different speeds, depending on one's genetics, environment and lifestyle. Synthetic antiocxidant products are many circulated in the market which have a negative impact on health. However Antioxidant compound are widely spread in nature expecially in plant. Moringa leaf is one of plants that contain abundant antioxidant, alkaloids, flavonoids, phenolics, triterpenoids/steroids and tannins. Many of people Switch to natural products. Mask from natural products are not causing irritation or less side effects. clay face mask are mostly used because of their skin rejuvenating abilities. Purpose: To know either Moringa leaf ethanol extract can be formulated in clay mask preparations and the optimal effect is to prevent aging or not. Methods: the research is including how to make clay mask with ethanol extract of Moringa leaves at concentrations of 6%, 8% and 10%. The evaluation of the physical quality of the preparation, testing the effectiveness of clay masks with ethanol extract of Moringa leaves as anti-aging. Result: the preparation is qualify the characteristic test, had a pH of 4.9-5.2, a drying time of 15-23.5 minutes, an o/w emulsion type, was stable for 12 weeks of storage, and was not caused irritation. The best result of anti-aging effectiveness test was at a concentration of 10% with 36.25 moisture content, 23.25 fineness content, 33.75 pores, 20.5 blemishes and 15.5 wrinkles. Conclusion: Moringa leaf ethanol extract can be formulated in clay mask , and is able to give the best anti-aging effect at 10% formula.

Page 10 of 24 | Total Record : 237

 8   9   10   11   12 

Filter by Year

2018 2025


Reset
Filter By Issues
All Issue Vol 8 No 1 (2025): Jurnal Farmasimed (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM) Vol 6 No 2 (2024): Jurnal Farmasimed (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM) Vol 4 No 1 (2021): Jurnal Farmasimed (JFM) Vol 3 No 2 (2021): Jurnal Farmasimed (JFM) Vol 3 No 1 (2020): Jurnal Farmasimed (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM) Vol 2 No 1 (2019): Jurnal Farmasimed (JFM) Vol 1 No 2 (2019): Jurnal Farmasimed (JFM) Vol 1 No 1 (2018): Jurnal FARMASIMED (JFM) More Issue