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Jurnal Prima Medika Sains
Published by Universitas Prima Indonesia
ISSN : 26863502     EISSN : 27146707     DOI : https://doi.org/10.34012/jpms
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Prima Medika Sains adalah jurnal ilmiah di bidang kesehatan dan kedokteran yang terbit dua kali dalam setahun yaitu pada bulan Juni dan Desember. Diterbitkan oleh Universitas Prima Indonesia yang secara teknis dikelola Program Studi Magister Kesehatan Masyarakat Fakultas Kedokteran Universitas Prima Indonesia. Berisi tulisan hasil penelitian lapangan atau laboratorium maupun studi pustaka di bidang kesehatan dan kedokteran.
Arjuna Subject : Kedokteran - Kesehatan Masyarakat, Kesehatan Lingkungan dan Pekerjaan
Articles 154 Documents
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Factors associated with early marriage Putri, Yulita; Ketaren, Sinar Otniel; Bangun, Henny Arwina; Nababan, Donal; Manurung, Jasmen
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.6277

Abstract

Early marriage among adolescents is a significant social issue that is often linked to unintended pregnancies resulting from premarital sexual activity. This cross-sectional study aimed to identify the factors associated with early marriage among teenagers in Kelurahan Sari Rejo, Medan Polonia, Indonesia, from October 2023 to May 2024. A total of 65 early married adolescents aged 15-18 years were included in this study. The findings revealed that parental education, socioeconomic status, and parenting style were not significantly associated with early marriage. However, information source and peer influence were significant predictors. Adolescents who engaged in unhealthy peer relationships were 2.20 times more likely to marry early than those with healthy peer associations. These results underscore the importance of peer influence and the need for comprehensive sex education programs to address early marriages among teenagers.
Predictors of hypertension among pregnant women Andriani, Risca; Purba, Jenny Marlindawani; Bangun, Henny Arwina; Nababan, Donal; Tarigan, Frida Lina
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.6291

Abstract

This study investigated factors associated with hypertension during pregnancy (HDP) in Langkat Regency, Indonesia, where HDP cases have been increasing. Conducted at Sei Bamban Health Center between November 2023 and April 2024, the study included 47 third-trimester pregnant women. Data on maternal age, parity, BMI, family history of hypertension, secondhand smoke exposure, dietary habits, physical activity, and antenatal care (ANC) adherence were collected via questionnaires. Gestational hypertension was defined as systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg. Bivariate and multivariate analyses were performed using SPSS. While age and parity showed no significant association with HDP, elevated BMI (≥22.9 kg/m²) (p=0.010; OR 5.120; 95%CI: 1.427-18.373), a history of hypertension (p=0.016; OR 4.411; 95%CI: 1.282-15.174), exposure to cigarette smoke (p=0.000; OR 27.273; 95%CI: 3.165-235.024), low fat/salt intake (p=0.000; OR 0.088; 95%CI: 0.020-0.382), low physical activity (p=0.000; OR 31.667; 95%CI: 5.676-176.680), and non-adherence to ANC (p=0.000; OR 17.944; 95%CI: 3.391-94.948) were significantly associated with HDP. These findings highlight the importance of ANC adherence and risk factor management, including lifestyle modifications, for HDP prevention. The study recommends targeted education, counseling, screening, and monitoring of at-risk pregnant women.
Assessing the implementation of occupational safety and health management system in the hospital Kartika, Ferina; Nasution, Sri Lestari Ramadhani
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.6364

Abstract

The implementation of occupational health and safety programs in hospitals aims to improve access, affordability, and quality of safe health services in hospitals. While some hospitals have implemented Occupational Safety and Health Management Systems (OSHMS), their effectiveness varies. This study aimed to examine and evaluate the effectiveness of OSHMS implementation in Hospital X. This qualitative research used a case study design. A purposive sampling technique was used in this study. The research informants selected included an OSH Committee Team of three people and seven hospital employees. This study used a combination of observation, in-depth interviews, and documentation methods to obtain comprehensive data on the implementation of OSHMS. Data analysis was conducted through a series of systematic steps, starting with the transcription of observation and interview results in textual form. The coded data were analyzed to identify patterns, meanings, and relationships between themes. Themes were analyzed deductively, focusing on policy, responsibility, and authority to act, and the review and evaluation of OSHMS. The results of this analysis were interpreted by the researcher and linked to the research context and relevant theories, resulting in useful and meaningful findings. The results showed that the hospital demonstrated a commitment to OSH through comprehensive policies and implementation efforts. However, there are still some shortcomings in terms of the person in charge of the OSH in the work unit, as well as review and evaluation mechanisms. Improvements in these aspects can help to increase the effectiveness of OSHMS implementation in hospitals.
The effect of moringa flower extract on kidney function in obese rats Meri, Meri; Lawrence, Christopher; Wilsen, Wilsen
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.3952

Abstract

This study aims to measure the effect of moringa flower extract administration on kidney function and histopathological features of the kidneys of obese male Wistar puith galir rats. This research is a type of experimental quantitative research using post-test only group design. This research was conducted at the Department of Pharmacy Pharmacology Laboratory, Faculty of Medicine, University of North Sumatra and Anatomical Pathology Laboratory, University of North Sumatra. Histopathology observation of kidney tissue was done by comparing the control and treatment groups. Changes observed will be the presence of fatty degeneration (vacuolization), necrosis and hydrophic degeneration. To obtain quantitative data, scoring was performed on each change found. The research data were tabulated and then the changes found were analyzed and presented descriptively. The research data were then analyzed with the help of SPSS version 25.0. The data normality test was analyzed with the Kolmogorov-Smirnov test approach (p> 0.05). To test the significance between test groups, one-way analysis of variance or One Way ANOVA technique was conducted at 95% confidence level (p < 0.05). Further analysis or test was conducted using Post Hoc Test with LSD technique. The results of the analysis showed that the administration of Moringa flower extract at a dose of 600 mg/KgBB was effective in improving kidney function in obese Wistar white rats. This improvement can be seen through the levels of ureum, creatinine, and histological structure of the kidneys that have improved. The results of histopathological observations of kidney tissue in treatment group 3, namely moringa flower extract at a dose of 600 mg/KgBB, experienced the most significant improvement and approached the control group compared to other groups.
The effect of binahong leaf extract on cardiac function in rats fed a high-fat diet Wahyudi, Dwi Sukma; Sartika, Dewi; Harahap, Alvin Abrar
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4067

Abstract

Several antioxidant defense mechanisms protect biological systems from the negative impact of ROS. Natural antioxidants are mainly obtained from plants, such as vegetables, and one of them is the binahong plant which is rich in antioxidants. This plant is often used traditionally as a blood-thinning drug to prevent stroke. This study aimed to evaluate the effect of binahong (anderera cardifolia) leaf extract on cardiovascular health and the histological structure of the heart of wistar male white rats fed a high-fat diet. This study is an experiment with a completely randomized design (CRD) consisting of 4 groups: normal control, treatment 1 dose 200 mg/kg BW, treatment 2 dose 300 mg/kg BW, and treatment 3 dose 400 mg/kg BW. Histopathological data such as aortic wall thickness and number of foam cells were analyzed using SPSS 23 with one-way ANOVA test and Post Hoc LSD at 0.05 significance level. The results showed that administering a dose of 400 mg/kg BW effectively reduced the thickness of the aortic wall and the number of aortic foam cells in rats.
Unmet need for family planning among women visiting community health Nathasia, Ingee; Rusip, Gusbakti; Mutia, Maya Sari
Jurnal Prima Medika Sains Vol. 6 No. 2 (2024): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i2.5569

Abstract

The unmet need for family planning is a significant reproductive health issue, particularly in developing countries. This study aimed to identify the factors associated with the unmet need for family planning among women visiting puskesmas in Medan City. This study used a cross-sectional design and included 186 participants. Data were collected using questionnaires. Data were analyzed using the chi-squared test and logistic regression. The results showed that age, education, knowledge, and perception of family planning were significantly associated with an unmet need for contraception (p<0.05). The younger the age, the lower the level of education, the lower the knowledge and perception of family planning, and the higher the likelihood of an unmet need for contraception. In contrast, family income and parity were not significantly associated with the unmet need for family planning. Satisfaction with family planning services was also not significantly associated with unmet need for contraception. The results highlight the importance of comprehensive interventions to address the unmet need for family planning. Educational programs targeting younger age groups, especially those with low educational levels, need to be improved. Additionally, efforts to improve knowledge and change community perceptions of family planning are crucial.
Recurrent flaccid paralysis due to hypokalemia as an unusual presentation of hypothyroidism Nainggolan, Prima Heptayana; Meliala, Terang
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.5741

Abstract

Background: Recurrent flaccid paralysis with low level of potassium can be found in hypokalemic periodic paralysis or thyrotoxic periodic paralysis. Hypokalemic Periodic paralysis associated with hypothyroidism is rare in the existing literature. Case illustration: A 41-year-old man had been admitted to the emergency ward due to weakness of his lower extremities for 3 days before the admission. He had the same symptoms one year ago. Based on the physical examination, decreases in both muscle strength and physiological reflexes in lower extremities had been found. From laboratory examination, the serum potassium level had reduced up to 1,7 mmol/l, with high TSHs and normal T3 and T4 level. The nerve conduction studies had revealed normal limits. Following a potassium correction, the patient had shown improvement. Discussion: In most cases, hypokalemic periodic paralysis is caused by pure hypokalemia or high thyroid hormone level in serum (as in thyrotoxic periodic paralysis). However, this patient was diagnosed as hypokalemic periodic paralysis with subclinical hypothyroidism. This case is therefore a very rare and unusual presentation of hypothyroidism. The relation between hypokalemic periodic paralysis and hypothyroidism remains unclear. Conclusion: Hypokalemic periodic paralysis associated with hypothyroidism is rare and understanding about this condition has not been established thus far in the literature. Thyroid examination is needed for patients with hypokalemic periodic paralysis.
The role of catechol-o-methyltransferase in postpartum depression Dewi, Indah Kusuma; Natasia, Caroline Putri; Gunadi, Julia Windi; Sanjaya, Ardo
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.5844

Abstract

The global prevalence of postpartum depression is increasing annually. This condition has been associated with polymorphisms in the catechol-O-methyltransferase (COMT) enzyme, which plays a critical role in the degradation of catecholamines. Therefore, a literature review was conducted to examine the influence of COMT enzyme variants on postpartum depression, with a focus on specific time periods and genetic variants implicated in the disorder. The review methodology involved a systematic search of articles on the PubMed database using the keywords "catechol-O-methyltransferase," "postpartum depression," and "role of COMT in postpartum depression." Inclusion criteria required full-text availability in either Indonesian or English. Four relevant studies were identified that investigated the relationship between COMT enzyme variants and postpartum depression. Evidence suggests that the COMT Val158Met polymorphism may affect the risk of postpartum depression in the context of elevated estrogen levels, as high estrogen concentrations are known to downregulate COMT expression. Additionally, certain single nucleotide polymorphisms (SNPs), including rs2020917 (TT genotype), rs737865 (GG genotype), and the COMT rs4680 Met variant allele, have been shown to modulate the influence of COMT on postpartum depression independently of estrogen levels, possibly through interactions with other enzymatic pathways.
Endobronchial hamartoma: Diagnostic challenges and clinical implications of a rare benign lung tumor Fazharyasti, Vininta; Wahyono, Djuwita Adi; Wardhana, Samuel Raymond Rumantir; Putranto, Terawan Agus
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.6112

Abstract

Introduction: Endobronchial hamartomas are rare benign lung tumors, representing only 0.025%–0.032% of all lung tumors and 1.4% of hamartomas. Originating in the bronchial passages, these tumors comprise cartilage, fat, fibrous tissue, and epithelium. Despite their benign nature, they can cause bronchial obstruction, post-obstructive pneumonia, and atelectasis. Case Report: A 68-year-old male presented with chronic cough and hemoptysis. Imaging revealed a calcified mass in the right lower bronchus, causing partial obstruction. Bronchoscopy identified a smooth, obstructive mass without bleeding or necrosis. Histopathological examination confirmed an endobronchial hamartoma, showing benign bronchial mucosa, cartilage, adipose tissue, submucosal glands, and myxoid stroma. Discussion: Diagnosing endobronchial hamartomas is challenging due to their rarity, nonspecific symptoms, and nonspecific imaging findings. Advanced imaging techniques, such as computed tomography (CT) scans, can identify calcifications or fatty components, aiding diagnosis. However, histopathological confirmation is crucial to differentiate these lesions from malignant or other benign pulmonary tumors. Early recognition and treatment are essential to prevent complications like recurrent infections and irreversible airway damage. Conclusion: Although rare, endobronchial hamartoma is a clinically significant benign lung tumor due to its potential to cause notable complications. The diagnostic challenge lies in its often nonspecific initial imaging findings. However, combining advanced radiology modalities, such as computed tomography (CT) and histopathological evaluation. Early recognition of this tumor from other pulmonary lesions is crucial for treatment and better patient outcomes.
Optimizing nutritional status with nutritional therapy in malnourished patient post whipple’s procedure: A case report Stefani, Shiela; Sunardi, Diana; Sonia, Steffi
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.6235

Abstract

The prevalence of malnutrition is considerably high among patients with pancreatic cancer and that Whipple procedure is associated with high morbidity and mortality rates. Post-Whipple procedure nutritional therapy can help to preserve nutritional status, accelerate recovery of functional capacity, and improve patient’s quality of life. A 65-year-old malnourished woman underwent Whipple procedure for adenocarcinoma of ampulla of Vater. Oral pre-operative nutrition was given in the form of normal food and oral nutritional supplement (ONS). Eight hours before surgery, the patient received ONS containing 30 g carbohydrate. The patient was given early enteral nutrition at <48 hours post-operatively and was given oral nutrition as soon as she regained consciousness. The patient experienced post-operative pancreatic fistula (POPF) grade A. Post-operative in-hospital and homecare nutritional therapy included supply of energy, macronutrients, micronutrients, and nutritional education adjusted to the patient’s clinical condition and intake tolerance. Energy intake during hospitalization attained 109% of the estimated total energy requirement that consisted of up to 1.9 g/kg/day protein. Homecare nutritional intake reached almost 2 times basal energy requirement with 2.2 g/kg/day protein intake. The patient experienced improvement of clinical symptoms, POPF, intake tolerance, glycemic control, and functional capacity. The patient was allowed to be discharged and treated in the outpatient clinic, without readmission in the next 2 months. Adequate hospital and homecare medical nutritional therapy in post-Whipple procedure may improve nutritional status and functional capacity, improve clinical outcome, and prevent readmission of patients.

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