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AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh
Published by Universitas Malikussaleh
ISSN : 24775231     EISSN : 25028715     DOI : https://doi.org/10.29103/averrous
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Averrous: Jurnal Kedokteran dan Kesehatan Malikussaleh (Averrous: Malikussaleh Journal of Medicine and Health - Averrous: MJMH*) is a peer-reviewed and open-access journal. Publishes by the Faculty of Medicine Universitas Malikussaleh in collaboration with the Institute for Research and Community Service (LPPM) Universitas Malikussaleh, which focuses on disseminating research findings that cover a wide range of subjects in medicine and health from basic medical and health sciences, applied sciences, and public health research. Original research papers, case studies, reviewed-articles are acceptable. Averrous: MJMH journals are published twice a year May and November. All research articles published in website Averrous: MJMH is free-downloaded according to the open access policy.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 336 Documents
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Characteristics of Risk Factors and Clinical Manifestations of Non-Hemorrhagic Stroke In Patients At Ibnu Sina Hospital, Makassar, 2023–2024 Muh. Althaf Firjatullah; Erlin Syahril; Suci Noviyanah Ansary; Moch. Erwin Rachman; Dwi Pratiwi
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.2 November 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v11i2.25421

Abstract

Non-hemorrhagic stroke is the most common type of stroke and a leading cause of morbidity and disability. This condition is generally triggered by blood flow disorders due to atherosclerosis, thrombosis, or embolism, with clinical manifestations such as sudden weakness, speech disorders, and decreased consciousness. In Indonesia, including South Sulawesi, the prevalence of stroke remains high, making the identification of risk factors and clinical symptoms crucial for optimal management. This study aims to describe in detail the risk factors for non-hemorrhagic stroke in patients recorded in the medical records of Ibnu Sina YW UMI Hospital in Makassar from 2023 to 2024, as well as to describe in detail the clinical manifestations of non-hemorrhagic stroke in patients recorded in the medical records of Ibnu Sina YW UMI Hospital in Makassar from 2023 to 2024. This study was conducted using a descriptive design through a cross-sectional approach. This type of research is quantitative. The results showed that the most dominant risk factor in non-hemorrhagic stroke patients at Ibnu Sina YW UMI Hospital in Makassar in 2023–2024 was hypertension (92.3%). Other risk factors found were family history (57.7%), genetic factors (53.8%), diabetes mellitus (23.1%), history of heart disease (13.5%), and dyslipidemia (11.5%). These findings indicate that the majority of patients had more than one risk factor, with hypertension being the main factor contributing to cerebral ischemia. The most common clinical manifestations were hemiparesis (90.4%), followed by vertigo (44.2%), ataxia (36.5%), aphasia (34.6%), nausea and vomiting (19.2%), and hemianesthesia (11.5%). This pattern shows that neurological deficits in the form of motor disorders are the most prominent symptoms in non-hemorrhagic stroke patients. This study shows that hypertension is the most dominant risk factor in non-hemorrhagic stroke patients, accompanied by family history and genetic factors. The most common clinical manifestations were hemiparesis, followed by vertigo, ataxia, and aphasia. These findings emphasize the importance of early detection of risk factors and recognition of characteristic neurological symptoms for the optimization of non-hemorrhagic stroke management.
The Effect Of Dangke Feeding On Body Mass Index In Male White Rats (Rattus Norvegicus) With Obesity From The Sprague Dawley Strain Kamali, Aqma Sabrina Kamali; Asrini Safitri; Ahmad Ardhani Pratama; Aryanti R. Bamahry; Dian Fahmi Itami
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.2 November 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v11i2.25451

Abstract

Obesity is defined as a metabolic disorder characterised by an increase in body fat mass and can lead to various chronic diseases. Dangke, a traditional fermented food from Enrekang, contains lactic acid bacteria which have been shown to have the potential to aid weight loss (Jones et al., 2022). The objective of this study was to ascertain the impact of dangke administration on the Body Mass Index (Lee Index) in male Sprague Dawley obese white rats (Rattus norvegicus). The present study was an experimental laboratory study with a pre-post-test design, incorporating a control group. The study involved 30 rats, which were divided into three groups: control, low-dose treatment (1.8 g/200 g BW), and high-dose treatment (3.6 g/200 g BW). Dangke was administered the substance for a period of 14 days via a feeding tube. The subsequent analysis of the data employed a range of statistical tests, including the Shapiro-Wilk, Levene, Paired Sample T-test, and One Way ANOVA. The findings indicated that there was no statistically significant difference in the control group (p = 0.893). However, the low-dose (p = 0.001) and high-dose (p = 0.004) groups demonstrated a substantial decrease in the Lee Index, indicating a dose-dependent response. The results of the analysis of variance (ANOVA) test following treatment indicated a significant difference between the groups (p = 0.002). The LSD follow-up test revealed a significant difference between the control group and the two treatment groups, but not between the low and high doses. The present study concluded that dangke significantly reduced the Lee Index in obese rats, although increasing the dose did not provide a significant additional effect. It is hypothesised that Dangke has the potential to be an alternative fermented nutritional intervention to aid weight loss.
The Relationship Between Premature Rupture of Membranes and the Decision to Perform a Cesarean Section and Neonatal Outcomes at Dr. Doris Sylvanius Regional General Hospital in Palangkaraya City from 2022 to 2024 Marta Eldina Larasati; I Gde Hary Eka Adnyana; Austin Bertilova Carmelita; Dian Mutiasari
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.2 November 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v11i2.25460

Abstract

Ketuban Pecah Dini (KPD) meningkatkan risiko infeksi, tindakan Sectio Caesarea (SC), serta komplikasi neonatal. Durasi KPD menjadi faktor utama yang memengaruhi keputusan persalinan dan kondisi bayi. Di RSUD dr. Doris Sylvanus Palangka Raya tahun 2022–2024, kasus KPD dan SC dengan indikasi KPD menunjukkan peningkatan, sehingga penting diteliti hubungan durasi KPD dengan keputusan SC dan outcome neonatus. Penelitian ini bertujuan untuk mengidentifikasi distribusi durasi KPD pada ibu bersalin di RSUD dr. Doris Sylvanus selama periode 2022-2024, untuk mengetahui proporsi tindakan persalinan (SC dan Pervaginam) berdasarkan durasi KPD di RSUD dr. Doris Sylvanus selama periode 2022-2024, untuk mengetahui distribusi outcome neonatus berdasarkan durasi KPD di RSUD dr. Doris Sylvanus selama periode 2022-2024, dan untuk menganalisis hubungan antara durasi KPD dan tindakan SC di RSUD dr. Doris Sylvanus selama periode 2022-2024, serta menganalisis hubungan antara durasi KPD dan outcome terhadap neonatus (NICU/Perinatologi atau rawat gabung) di RSUD dr. Doris Sylvanus selama periode 2022-2024. Penelitian ini menggunakan desain studi deskriptif observasional dengan pendekatan cross-sectional (potong lintang). Hasil penelitian menunjukkan bahwa mayoritas ibu dengan KPD mengalami durasi pecah ketuban ≥12 jam, yaitu sebesar 78,7% dari seluruh kasus. Sebagian besar ibu dengan KPD menjalani tindakan Sectio Caesarea (70,0%), terutama pada kelompok dengan durasi KPD ≥12 jam. Neonatus dari ibu dengan KPD mayoritas (77,9%) memerlukan perawatan di unit perinatologi, terutama pada kasus dengan durasi KPD ≥12 jam. Terdapat hubungan signifikan antara durasi KPD dan tindakan SC (χ² = 48,369; p < 0,001), di mana ibu dengan durasi KPD ≥12 jam memiliki peluang hampir 9 kali lebih besar untuk menjalani SC. Durasi KPD juga berhubungan signifikan dengan outcome neonatus (χ² = 44,493; p < 0,001), dengan risiko 8 kali lebih tinggi untuk dirawat di unit perinatologi pada bayi dari ibu dengan KPD ≥12 jam. Maka dapat disimpulkan bahwa durasi KPD ≥12 jam berhubungan erat dengan meningkatnya tindakan SC dan kebutuhan perawatan intensif neonatus. Semakin lama ketuban pecah, semakin tinggi risiko intervensi obstetri dan komplikasi neonatal di RSUD dr. Doris Sylvanus periode 2022–2024.
Comparative Effectiveness of Epidural Levobupivacaine Analgesia and Fentanyl Elastometric Pump For Postoperative Pain Management at Dr. Zainoel Abidin Regional General Hospital, Banda Aceh Al-Muqsith, Al-Muqsith
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.2 November 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v11i2.25737

Abstract

Postoperative pain management plays a pivotal role in optimizing surgical recovery and minimizing postoperative morbidity. In clinical practice, epidural analgesia and continuous intravenous opioid administration via elastomeric pumps are commonly utilized to control postoperative pain. This study aimed to evaluate and compare the analgesic effectiveness and adverse event profiles of continuous epidural levobupivacaine infusion and fentanyl administration using an elastomeric pump in patients undergoing digestive and gynecological surgery at Dr. Zainoel Abidin Regional General Hospital, Banda Aceh. This analytic comparative observational study included adult postoperative patients who received either epidural levobupivacaine or intravenous fentanyl via elastomeric pump. Pain intensity was assessed using the Numeric Rating Scale (NRS) at 24 and 48 hours postoperatively. Statistical analysis was conducted using the Mann–Whitney U test. Both analgesic modalities achieved satisfactory postoperative pain control, with no statistically significant differences in NRS scores at 24 hours (p = 0.759) and 48 hours (p = 0.050). Opioid-related adverse effects, including nausea, vomiting, and sedation, were more frequently observed in the fentanyl group, whereas hypotension occurred in a small proportion of patients receiving epidural analgesia. These findings indicate that continuous epidural levobupivacaine and fentanyl elastomeric pump provide comparable effectiveness and safety for postoperative pain management following digestive and gynecological surgery.
Association Between Adverse Drug Reactions to Anti-Tuberculosis Drugs and Medication Adherence Among Pulmonary Tuberculosis Patients Sahputri, Juwita; Siregar, Sarah Rahmayani; Azhari, Teuku; Pulungan, Alyifia Yulia Maura
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.2 November 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v11i2.26068

Abstract

Tuberculosis (TB) is a significant global public health issue, particularly in developing countries. Indonesia ranks second in the world in terms of TB burden. Adherence to anti-tuberculosis drug (ATD) regimens is crucial for effective TB treatment; however, side drug reactions often hinder adherence. This study examined the relationship between ATD-related side effects and medication adherence among pulmonary tuberculosis patients receiving treatment at the Pulmonary Clinic of RSUCM Aceh Utara. Employing a descriptive analytical design with a cross-sectional approach, we enrolled 74 patients through purposive sampling and collected data using questionnaires. The results showed that most patients experienced minor side effects (70.3%), with urine discoloration (97.3%), nausea (74.3%), and arthralgia (58.1%) being the most common. Patient medication adherence levels were classified as follows: 50% adherent, 29.7% moderately adherent, and 20.3% non-adherent. The chi-square analysis showed a significant statistical link between the side effects of ATD and patients' adherence to their medication regimen (p < 0.001). In conclusion, there is a significant relationship between ATD-related side effects and decreased medication adherence. Proactive management of these side effects and comprehensive patient education are essential. Keywords: anti-tuberculosis drugs; medication adherence; side effects
Admission Blood Pressure Severity as a Predictor of Stroke Subtype and Early Neurological Deterioration: A Retrospective Cohort Study Ikhsan, Maulana; Asmaul Husna, Cut
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.2 November 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v11i2.26093

Abstract

This study investigated the significance of admission systolic blood pressure (SBP) severity as a predictor of stroke subtype and early neurological worsening in a group of 220 acute stroke patients. We conducted a retrospective analysis, classifying entry systolic blood pressure in accordance with American Heart Association standards and assessing outcomes related to stroke subtype (hemorrhagic versus ischemic) and early neurological deterioration (END), the latter extracted from clinical notes. Upon controlling for age, sex, diabetes, and cholesterol, we observed that admission systolic blood pressure was markedly elevated in individuals with hemorrhagic stroke. Every 10 mmHg elevation in systolic blood pressure (SBP) augmented the adjusted odds of hemorrhagic stroke by 42%, whereas patients experiencing a hypertensive crisis (SBP ≥180 mmHg) exhibited a five-fold increased likelihood of hemorrhagic stroke relative to normotensive individuals. A hypertensive crisis was independently linked to an almost three-fold elevation in the likelihood of early neurological impairment. The correlation was most pronounced in individuals below 50 years of age. We determine that the severity of entry systolic blood pressure is a significant, independent predictive marker for hemorrhagic stroke subtype and early clinical deterioration, highlighting its essential function in acute stroke evaluation and treatment.

Page 34 of 34 | Total Record : 336

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