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AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh
Published by Universitas Malikussaleh
ISSN : 24775231     EISSN : 25028715     DOI : https://doi.org/10.29103/averrous
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Averrous: Jurnal Kedokteran dan Kesehatan Malikussaleh (Averrous: Malikussaleh Journal of Medicine and Health - Averrous: MJMH*) is a peer-reviewed and open-access journal. Publishes by the Faculty of Medicine Universitas Malikussaleh in collaboration with the Institute for Research and Community Service (LPPM) Universitas Malikussaleh, which focuses on disseminating research findings that cover a wide range of subjects in medicine and health from basic medical and health sciences, applied sciences, and public health research. Original research papers, case studies, reviewed-articles are acceptable. Averrous: MJMH journals are published twice a year May and November. All research articles published in website Averrous: MJMH is free-downloaded according to the open access policy.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 336 Documents
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Health Promotion Media Intervention Towards Balanced Nutrition Knowledge to Increase Immunity in Inspired Families in Uteunkot Village, Lhokseumawe City Novalia, Vera; Utariningsih, Wheny; Zara, Noviana; Meutia, Zahra; Imanda, Fetty
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 10 No.2 November 2024
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v10i2.18791

Abstract

Nutritional problems are a health problem because the morbidity rate is very high throughout the world, including Indonesia, which has complex nutritional problems, namely stunting, wasting, and overweight. Data in Lhokseumawe City shows that the percentage of malnutrition among toddlers aged 0-59 months is 5.2%; short or very short, often known as stunting, has a percentage of 3.9%; underweight or very thin toddlers have a percentage of 3.4%. So, it is necessary to increase body immunity through health promotion media. This research aims to determine Health Promotion Media on Knowledge of Balanced Nutrition to Increase Body Immunity in Assisted Families for 150 respondents. The research method used is quasi-experimental, using a one-group pretest-posttest design. Data was collected using a questionnaire sheet. The research results showed that the characteristics of most respondents in the age group were 59 (39.3%). The research results showed an increase in knowledge to 96.7% in the excellent category after the intervention. The use of audiovisual media influences knowledge based on the Wilcoxon test with a p-value of 0.000. This research concludes that there is an influence of audiovisual media on knowledge about balanced nutrition to increase immunity in the Uteunkot village community
Relationship between Knowledge Level of Clean and Healthy Living Behaviour (PHBS) with Dental and Oral Hygiene at the Quranic House Bustanul Mustafa Lhokseumawe Syafrida, Anita; Deriansyah, Muhammad; Fardian, Nur; Yasin, Muhammad; Naufal, Muhammad Andre; Nasywa, Irandary
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 10 No.2 November 2024
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v10i2.16136

Abstract

Dental and oral health is the healthy condition of the hard and soft tissues of the teeth and related elements in the oral cavity. This study aims to analyze the relationship between the level of knowledge regarding Clean and Healthy Living Behavior (PHBS) and dental and oral hygiene among students at Rumah Quran Bustanul Mustafa Lhokseumawe. This research uses a descriptive correlation design with a cross-sectional approach. The sample consisted of 62 students selected using purposive sampling technique. The instruments used include a questionnaire to measure the level of PHBS knowledge, which has been tested for validity and reliability, as well as a dental and oral hygiene observation sheet using the OHI-S (Oral Hygiene Index-Simplified) index. Data analysis was carried out using the Spearman correlation test with a significance level of 0.05. The results of the study showed that there was a significant relationship between the level of PHBS knowledge and oral hygiene with a value of p = 0.000 (<0.05). The correlation value of -0.654 shows a strong and negative relationship, where the higher the student's level of knowledge, the better their level of dental and oral hygiene. The distribution of knowledge levels shows that 48.38% (30 students) have good knowledge, 32.26% (20 students) have sufficient knowledge, and 19.36% (12 students) have poor knowledge. Meanwhile, students' oral hygiene showed that 29.04% (18 students) had good hygiene, 38.70% (24 students) had sufficient hygiene, and 32.26% (20 students) had poor hygiene. In conclusion, there is a significant relationship between the level of PHBS knowledge and dental and oral hygiene among students at Rumah Quran Bustanul Mustafa Lhokseumawe. These results emphasize the importance of PHBS education to improve children's dental and oral health.
Relationship Between Glomerular Filtration Rate and Anemia in Chronic Kidney Disease Patients at RSUD Dr. H. Chasan Boesoirie Pongsinaran, Fermat Mangiwa; Ambar, Edwin; The, Fera
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 10 No.2 November 2024
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v10i2.17296

Abstract

Chronic kidney disease (CKD) is a condition of decreased kidney function with signs of damage to the kidneys or both, with a minimum duration of 3 months. CKD patients will experience anemia due to a decrease in the ability of the kidneys to produce erythropoietin in balance. The purpose of this study was to determine the relationship between glomerular filtration rate and anemia in CKD patients at Dr. H. Chasan Boesoirie Hospital. This type of research is analytic observational cross-sectional research using Spearman's rho test. The sample in this study were patients who were taken using the total sampling technique. Data collection tools in the form of medical records at Dr.H. Chasan Boesoirie Hospital in 2020-2022. This study found that the distribution of CKD patients was mostly female 52 patients (53.6%), most in the age group 55-64 years 36 patients (37.1%), most hemoglobin levels were found to be below normal or anemia 91 patients (93.1%), and most GFR in GFR <15 ml/min/1.73m2, namely 89 patients (91.8%). The results of bivariate analysis showed that there was a relationship between glomerular filtration rate and anemia with a p-value = 0.039 (p <0.05) and a correlation coefficient of 0.210 indicating that the direction of the correlation was positive with a very weak correlation strength. There is a relationship between glomerular filtration rate and anemia in patients with chronic kidney disease at Dr. H. Chasan Boesoirie Hospital.
Histological Study of Effect of Oral Administration of Monosodium Glutamate (MSG) on Duodenum of Wistar Rats Rahayu, Mulyati Sri; Perwira Awaludin, Lambang Rizki; Wahyuni, Sri
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 10 No.2 November 2024
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v10i2.17993

Abstract

Monosodium glutamate (MSG) is a widely marketed flavor enhancer that is regularly consumed. MSG is toxic to several organs including the small intestine. Previous studies have reported the effects of high doses of MSG; however, these findings are not directly applicable to equivalent human intakes. This study aimed to investigate the effect of MSG on the duodenum in rats administered with human average daily intake (ADI). Twenty-four adult male Wistar rats weighing 150-250 g at the age of 8-12 weeks were divided into four experimental groups (n = 6): normal control group (C), group 1 (0.378 mg/g b.wt), group 2 (0.756 mg/g b.wt), and group 3 (1.512 mg/g b.wt) oral MSG per day for 21 days. Duodenaltissue was dissected and stained with hematoxylin and eosin (HE) for histological examination. Data analysis was performed using the Kruskal-Wallis test (p < 0.05). The average height of the villus was calculated for each group: control (1047.40 ± 158.0 µm), Group 1 (850.68 ± 202.38 µm), Group 2 (906.29 ± 416.63 µm), and Group 3 (877.55 ± 154.65 µm). There was a difference in the height of the villi between all groups; however, there was no statistically significant difference compared with the control group (p = 0.384). The control group showed a normal appearance of the duodenal mucosa without inflammatory cells. In contrast, the treatment group showed inflammatory cell infiltration and lacked distinct brush-border structures. Our study showed that administration of MSG at an estimated dose of human ADIresulted in histological damage to the duodenum. 
The Effect of Bidens pilosa Extract on Vancomycin-Induced Acute Kidney Injury in Prepubertal Rats Priawan, Indra; Harahap, Armansyah Maulana; Siregar, Sarah Rahmayani
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 10 No.2 November 2024
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v10i2.19225

Abstract

The long-term use of Vancomycin and its administration at inappropriate doses still cause uncontrolled physiological side effects, particularly in terms of kidney development and metabolism. This study aims to investigate the effects of Bidens pilosa extract (BPE) on vancomycin-induced acute kidney injury in prepubertal rats. This study employed an experimental research method, randomly dividing 40 female Wistar rats into five equal groups: control/adult (C), prepubertal (P), prepubertal + Bidens pilosa (PB), prepubertal + vancomycin (PV), and prepubertal + vancomycin + Bidens pilosa (PVB). Gentamicin caused kidney damage in both PG and PVB groups. We treated PB and PVB with a single dose of BPE. At necropsy, we collected blood, serum, and kidney tissue for evaluation. The research results showed that the total leukocyte count was higher in PB compared to the others (P = 0.002). Serum urea, creatinine, aspartate aminotransferase, and total protein levels significantly increased in PB, PV, and PVB compared to C and P. Glutathione levels were low in the serum and kidney tissue of PV, and malondialdehyde levels were high compared to the others (P<0.05). Using BPE in vancomycin-induced acute kidney injury in ovariectomized rats resulted in a decrease in serum creatinine, urea, and malondialdehyde levels in PVB compared to PV, an increase in glutathione levels, and a milder severity of histopathological findings. The conclusion of this study shows that a single dose of BPE partially reduces kidney damage in rats with gentamicin-induced acute kidney injury
Analysis of Risk Factors for Acute Myocardial Infarction Arlindyo, Muhammad Vieraldo Berly; Faizin, Chamim; Noviasari, Nina Anggraeni; Setiawan, Muhammad Riza
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 10 No.2 November 2024
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v10i2.18092

Abstract

Cardiovascular disease is the most common cause of death in the world. One part of cardiovascular disease is acute myocardial infarction. There are risk factors that have the potential such as age, gender, genetics, hypertension, smoking, dyslipidemia, and diabetes mellitus. This study aims to analyse the risk factors associated with acute myocardial infarction. This study was conducted in October 2023, using an analytical observational study type and cross-sectional design. This study used medical record data from AMI patients from June 2022 - June 2023. The study sample was respondents diagnosed with acute myocardial infarction at ROEMANI Hospital taken through total sampling. Inclusion was 60 and exclusion was 14 respondents. Data analysis uses the chi-square The results showed that those who had a significant relationship with the incidence of acute myocardial infarction included hypertension (p = 0.001), diabetes mellitus (p = 0.022), smoking (p = 0.045), and those who did not dyslipidemia (p=0.639). In conclusion, there is a significant relationship between hypertension, diabetes mellitus, and the incidence of acute myocardial infarction. At the same time, dyslipidemia does not have a significant relationship with the incidence of acute myocardial infarction.
Effects of Black Garlic Extract Against Monosodium Glutamate-Induced Liver Damage in Rats: Macroscopic Studies Maulina, Nora; Zachreini, Indra; Gholib, Gholib; Akmal, Muslim
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.1 Mei 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v11i1.18815

Abstract

Monosodium glutamate (MSG) enhances flavor during food processing by providing an umami taste, but its metabolic by-products can cause liver injury. The liver is crucial for the metabolism of xenobiotics including glutamate. Black garlic, derived from fresh garlic (Allium sativum L.) through chemical reactions and heat treatment, may have hepatoprotective properties; however, studies are limited. This study assessed the hepatoprotective effects of black garlic extract (BGE) on MSG-induced liver damage. Twenty-five Wistar rats (Rattus norvegicus) were divided into five groups (n = 5): P0 (negative control); P1 (MSG group), 8 mg/kg MSG for 21 days; and P2, P3, and P4, receiving the same MSG protocol as P1 plus BGE doses of 200, 400, and 600 mg/kg body weight, respectively, for 16 days. After the experiment, rats were euthanized for liver tissue extraction. Although liver weights in the BGE-treated groups were lower than those in the MSG group, the difference was not statistically significant. These results indicated that a BGE dose of 200 mg/kg body weight mitigated MSG-induced hepatic damage. Further biochemical and histological studies are required to elucidate the mechanism of BGE's hepatoprotective action of BGE against MSG-induced hepatotoxicity.
Risk Factors Of Type 2 Diabetes Mellitus In The Working Area Of The Kalumata Public Health Center Lamasila, Ismy Hanifa; Permana, Dini Rahmawati; Marsaoly, Ryan Rinaldy
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.1 Mei 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia, insulin function, or both. In Indonesia, the number of people with DM reaches 8.5 million, making it the 7th in the world. According to the 2018 Riskesdas report, the prevalence of DM in North Maluku was recorded at 15,381 cases and was the second highest DM case, of which 2,822 cases were found in Ternate City. This study aims to determine the risk factors for type 2 diabetes mellitus in Kalumata Health Center. This study uses a type of quantitative research using case control observational research design, data collection tools in the form of medical records at Kalumata Health Center and primary data using questionnaires, the population of this study were DM and non-DM patients, the sample size of this study was 100 samples, the sampling technique used simple random sampling, this research was conducted in September-December 2024 and the analysis used was chi-square analysis and logistic regression. Of the total 100 samples obtained, the risk factor associated with the incidence of type 2 DM is age with a risk of 0.202 times (p=0.025; 95% CI 0.053-0.768). With this study, it is hoped that it can provide insight into the risk factors for Type 2 Diabetes Mellitus. Thus, the results can be utilized to organize routine counseling.
An Overview of Antibiotic Use, Length of Stay, and Amputation Incidents in Diabetic Foot Patients at Cut Meutia Regional Hospital Debbyousha, Maulina; Bayu Rizaldy, Muhammad; Syifa, Siti
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.1 Mei 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetic foot ulcer is a condition of ulceration on the skin surface associated with neuropathy and angiopathy in the lower extremities. Improperly treatment for diabetic foot resulting significant functional and financial consequences for the patient. The purpose of study was to determine and assess an Overview of Antibiotic Use, Length of Stay and Amputation Incidents in Diabetic Foot Patients at Cut Meutia Regional Hospital. This type of research is descriptive research using a purposive sampling method with a cross-sectional approach with a sample size of 55 people using the Slovin formula. Data were processed using the univariate method with the results in the form of characteristics of patients are middle age 45-59 years (42.5%), the most patients were male (57.5%) and the majority of patients were housewives (36.3%). The most common description of antibiotic usage is combination antibiotics (71.3%) with the majority is a combination of cephalosporin and metronidazole (48.8%). The most commonly prescribed single antibiotics are cephalosporins (25%). Meanwhile, the length of stay was <7 days (55%) and the majority of patients did not experience amputation (76.3%). The conclusion of this study was the majority of patients were men, middle age 45-59 years, the majority of occupations were housewives, The use of antibiotics was dominated by a combination of cephalosporins with metronidazole and the single antibiotic used was a cephalosporin, the length of stay was <7 days, and the patients did not experience amputation. Keywords: diabetic ulcer, antibiotics, combination therapy, complication
Tracing Mumps in Rural Area: A Clinical Profile of Infected Children and Adolescents in Bulu, Tuban Dion, Aldy; Pribadi, Florence; Dewi, Karina
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.1 Mei 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mumps, also known as epidemic parotitis, is a viral infection that affects the salivary glands. This disease commonly occurs among school-aged children and adolescents. According to data from the World Health Organization (WHO), the incidence of mumps in Southeast Asia (excluding Indonesia) reached 8,985 cases in 2022. In Indonesia, the Ministry of Health reported 6,593 cases in 2024. Given these challenges and the high number of cases found in the community, researchers aimed to study the clinical profile of mumps in school-aged children and adolescents in Bulu, Tuban. This research was observational in nature, using a descriptive cross-sectional study design. The findings revealed that male children are at higher risk of contracting mumps, with the highest infection rate observed in the 8-10 year age group. Areas characterized by close-knit living conditions and low immunization coverage reported a higher incidence of mumps. The most common complaint that led patients to seek medical care was cheek pain. Additionally, a significant number of mumps patients were found to be underweight. The most frequently administered treatment involved a combination of analgesic and vitamin.

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