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Hydrogen: Jurnal Kependidikan Kimia
ISSN : 23386487     EISSN : 26563061     DOI : Prefix 10.33394
Core Subject : Science, Education,
Hydrogen: The Chemistry Education Journal published by the Chemistry Education Study Program which contains articles raised from the results of conceptual research and studies in chemistry and chemistry education including education and learning, device development, media and learning models.
Articles 618 Documents
Development of An Inquiry-Based Ethnochemistry Textbook To Improve Students' Scientific Literacy and Understanding Hendrawani, Hendrawani; Hatimah, Husnul; Safitri, Baiq Rina Amalia; Pahriah, Pahriah
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 2 (2025): April 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i2.15467

Abstract

This research aims to develop an ethnochemistry-based chemistry textbook with an inquiry approach to increase students' scientific literacy and understanding of chemical concepts. The research method used is Research and Development (R&D) with a 4D model (Define, Design, Develop, Disseminate). The textbook was tested on class X I students at MA Daru Muhyiddin NW Santong. The validation results show very good quality, with an average score of 4.75 from experts, 4.5 from practitioners, and 4.3 from students. This book is considered relevant to the curriculum, effective in increasing student understanding, and connecting chemistry with local culture. Suggestions for development include adding a glossary, visualization, and variations in inquiry activities. This book has great potential as an innovative learning medium based on local culture.
Synthesis and In Silico Study of 5’-Chloro-2’,4-Dihydroxy-3-Methoxychalcone as Potential Inhibitors of Estrogen Receptors Alpha Putri, Rizka Amalia; Nurramadhani, Aisyah Zahra; Islami, Agustina Amalia; Tristania, Auriel Wafiq; Aulia, Isma; Farah, Harra Ismi; Arifian, Hanggara; Rahmadani, Agung
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 2 (2025): April 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i2.15546

Abstract

The high prevalence of breast cancer necessitates the discovery of new, more effective, and safer anticancer compounds. Chalcone, a flavonoid with promising anticancer activity, is limited by poor bioavailability and rare natural occurrence. In this study, a novel chalcone derivative, 5'-chloro-2',4-dihydroxy-3-methoxychalcone, was synthesized on a laboratory scale via Claisen-Schmidt condensation using 5-chloro-2-hydroxyacetophenone and 4-hydroxy-3-methoxybenzaldehyde as starting materials. The structure of the synthesized compound was confirmed by mass spectrometry and NMR analysis. Pharmacokinetic and toxicity profiles were predicted in silico using SwissADME, while molecular docking simulations with the ERα receptor were performed using AutoDockTools. The compound was obtained as a yellow solid with a yield of 70.15%, showed favorable ADME properties based on Lipinski’s and Veber’s rules, and demonstrated a binding energy of -7.82 kcal/mol to the ERα receptor, indicating potential as an anticancer agent. The novelty of this research is the successfully synthesized and characterized of this specific chalcone, which is structurally different from previously reported analogs. These findings enrich the diversity of chalcone derivatives and provide a new basis for developing synthesis-based drug candidates targeting breast cancer.
Alpha Amylase Inhibitory Activity of Curcumin Analogs and Its Synergy with Ferulic Acid in Vitro Nafillah, Khoirotun; Ariyani, Helena Devi; Asfirah, Lia Retian
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.15683

Abstract

Curcumin analog compounds are α,β unsaturated compounds through simplifying the beta diketo group to monoketo, which has better bioavailability and a more stable structure than curcumin compounds. This study aims to determine the α-amylase inhibitory activity on symmetric curcumin analog compounds, namely the compounds 2,6-bis(3,4-dimethoxybenzylidine)cyclohexanone (A) and 2,6-bis(3,4-dimethoxybenzylidine)cyclopentanone (B). as well as testing its synergistic interaction with ferulic acid in vitro. The α-amylase inhibition test was carried out using an iodine reagent and a starch solution as a substrate. The absorbance value was measured using a UV-vis spectrophotometer (λ 568 nm), and the % inhibition was calculated. The average value of the optimum α-amylase inhibition percentage for compounds A, B, and ferulic acid, respectively is 58.17%; 22.95%, and 93.52%. Based on the synergistic interaction, it was concluded that compounds A and B showed synergistic activity with ferulic acid. The percentage of α-amylase inhibition in the concentration ratio of curcumin analog A: ferulic acid (1:8) was 98.65%, and curcumin analog B: ferulic acid (1:4) was 98.37%. This shows that combining compounds between symmetrical curcumin analogs and ferulic acid can increase the activity of antidiabetic drug candidate compounds compared to single compounds. This study offers a new approach by testing the potential combination of curcumin and ferulic acid analogues as α-amylase inhibitors in vitro, demonstrating a synergy that has not been widely explored and opening up opportunities for developing more effective natural antidiabetic therapies.
Comparative Analysis of Antioxidant Potential in Hexane and Methanol Fractions of Sungkai Leaves Deswita, Elvira; Imelda, Imelda; Suryati, Suryati
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.15692

Abstract

This study aimed to compare the antioxidant potential of hexane and methanol fractions of sungkai (Paronema canescens Jack) leaves from Tanah Datar Regency, West Sumatra, Indonesia. The methanol extract was then fractionated using hexane and ethyl acetate. Total phenolic content was determined using the Folin-Ciocalteu method and antioxidant activity was evaluated using the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. According to the conducted research, the methanol fraction exhibits a significantly higher total phenolic content, quantified at 92.22 mg GAE/g, in contrast to the hexane fraction, which recorded a content of 25.33 mg GAE/g. Furthermore, the methanol fraction demonstrated robust antioxidant activity, with an IC50 value of 75.425 mg/L, whereas the hexane fraction demonstrated comparatively weaker antioxidant activity, with an IC50 value of 232.595 mg/L. The strong antioxidant activity of the methanol fraction can be attributed to its high content of phenolic compounds, such as flavonoids and tannins, which are known to possess potent antioxidant properties. The synergistic effects of these compounds may further enhance the overall antioxidant capacity of the methanolic fraction. In conclusion, the methanol fraction of sungkai leaves from Tanah Datar Regency demonstrates superior antioxidant potential compared to the hexane fraction, suggesting its potential as a natural source of antioxidants for various applications.
Educational Magazine Contains Phytochemical Screening Materials for Chemistry Education Students: Development and Validation Furnapasta, Lestia; Sofia, Baiq Fara Dwirani
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.15768

Abstract

This study aims to develop and validate an educational magazine as supplementary reading material for chemistry education students, focusing on the phytochemical screening of renggak leaf extracts using methanol and ethanol as solvents. The development of this magazine was carried out using a 4D model which was carried out until the third stage. The three stages are Define, Design, and Develop. Validation was conducted by three experts, and the evaluation results, analyzed using the Aiken V formula, yielded a score of 0.86, categorized as highly valid. Practicality testing with students indicated a score of 88%, demonstrating that the magazine is effective and user-friendly as a learning medium. Thus, this magazine is a viable supplementary resource for chemistry education students, particularly in understanding secondary metabolite compounds and phytochemical screening. The novelty of this research lies in the development of a visual educational magazine based on the phytochemical screening of Amomum dealbatum leaves, which has not been previously presented in this format to support chemistry learning.
The Effect of Collaborative Problem Solving Learning Model on Students' Collaboration Skills in Chemistry Learning Lestari, Wahyu Yunita; Erika, Farah; Rahmadani, Agung
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.15784

Abstract

The low collaboration skills of students are due to the less-than-optimal role of the teacher in fostering interpersonal skills and cooperation in the classroom. Selecting an appropriate learning model is key to effectively enhancing students' collaboration skills. Therefore, the Collaborative Problem Solving (CPS) learning model optimizes students' collaboration skills. This study aims to determine the effect of the Collaborative Problem Solving (CPS) model on students' collaboration skills in elements, compounds, and mixtures. The approach employed is a quasi-experimental design utilizing a non-equivalent control group format. All 8th-grade junior high school students in Samarinda for the 2023/2024 academic year served as the population in this study. Class VIII A was assigned as the experimental group, whereas Class VIII B was the control group. The sample was selected using purposive sampling based on the subject teacher’s considerations, including classroom participation, group collaboration, and peer interaction. The instrument used was a collaboration skills questionnaire consisting of 25 statement items, utilizing a 5-point Likert scale. Data collection was also carried out using an observation sheet developed based on the indicators of collaboration skills. The data were analyzed descriptively after being collected through observations and collaboration skill questionnaires. The findings indicated that the experimental group achieved a higher average score than the control group, indicating that the CPS model syntax positively improved students' collaboration skills.
Students’ Misconceptions in Chemistry Learning: A Systematic Literature Review from 2015 to 2025 Pahriah, Pahriah; Sudatha, I Gde Wawan; Suartama, I Kadek; Santosa, Made Hery
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.15805

Abstract

This study aims to identify the forms of misconceptions in chemistry learning, the methods/instruments used to detect these misconceptions, and effective instructional strategies to address them through a Systematic Literature Review (SLR) approach. The review was conducted on 24 scientific articles published between 2015 and 2025, obtained from the Scopus and Google Scholar databases (via Publish or Perish). Article selection was carried out in stages following the PRISMA flow, and the results were analyzed using a thematic content analysis approach. The review findings indicate that the topics most frequently associated with misconceptions are chemical bonding, acid-base concepts, chemical equilibrium, and reaction rates. The most commonly used instruments to identify misconceptions are three-tier diagnostic tests, followed by interviews and two-tier tests. Effective instructional strategies include the use of multiple representations, digital simulations, the 5E model, inquiry-based learning, and educational games. The study also revealed several research gaps, such as the lack of longitudinal studies, limited topic coverage in chemistry, and the underutilization of interactive digital technologies. Therefore, the development of innovative learning approaches and technology-based conceptual assessments is necessary to sustainably reduce misconceptions in chemistry learning.
General Chemistry Class Perspective On The Utilization Of Young Coconut water To Treat Fever Symptom Ridho, Dimas; Juwitaningsih, Tita; Samosir, Rafidah Almira; Pratiwi, Alfira Julian; Ardila, Mutia; Kurniawan, Ekin Dwi Arif; Sianipar, Mirna Wulan Sari; Alisya, Syalwa Nur; Br. Hutahuruk, Novitasari; Tafonao, Firman Satria
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.15819

Abstract

This study aims to analyze the perspectives of students from the Department of Mathematics enrolled in a General Chemistry class regarding the use of young coconut water as a natural remedy to treat fever symptoms. The research is grounded in the widespread trust of Indonesian society in herbal medicine, particularly young coconut water, which has been traditionally used across generations to treat various health conditions, including fever. Young coconut water is known to contain vital nutrients such as electrolytes (potassium, sodium, magnesium), B-complex vitamins, and vitamin C, which help lower body temperature naturally, especially during dehydration caused by fever. A quantitative approach with a descriptive survey method was employed. The data were collected using a closed questionnaire based on a Likert scale, which was tested for validity and reliability, achieving a Cronbach's Alpha value of 0.977-indicating a high level of reliability. Results showed that students' average scores in knowledge (3.90), understanding (3.81), attitude (3.89), and application (3.87) were all in the high category. This indicates that students not only understand the benefits of young coconut water but also grasp scientific concepts related to electrolyte function in fluid balance and immune response. Despite the high scores, some misconceptions persist. For example, a few students believe young coconut water can entirely replace medical treatment or that higher consumption leads to faster healing without regard for appropriate dosage. This highlights the need for improved science-based health literacy. The study concludes that continuous health education through lectures, seminars, and healthy campus campaigns integrating both traditional and medical approaches is essential. These findings are significant in promoting the wise and measurable use of natural remedies like young coconut water while avoiding misuse. Furthermore, the results can serve as a basis for future research, such as clinical trials or laboratory comparisons with other rehydration fluids, and can help develop health promotion policies in academic settings to encourage smart and healthy decision-making among students.
Improving Students’ Creative Thinking Skills through Problem Based Learning on Colloid: A Lesson Study Practice Munawaroh, Siti; Herunata, Herunata; Silviani, Silviani
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.15840

Abstract

This study aims to improve students' creative thinking skills with Problem Based Learning (PBL) model assisted google sites on through lesson study practice on colloid topic. The research was conducted in the form of Classroom Action Research (CAR) over two open class cycles involving 34 students of class XI-C at state senior high school (SMAN) 2 Malang. The learning strategies used were mind mapping in cycle I and colloid-based product design projects in cycle II. Data were collected through observation sheets and creative thinking skills questionnaires based on Torrance’s indicators: fluency, flexibility, originality, and elaboration. The results showed a significant increase in the average score of students' creative thinking skills from 1.97 (fair) in cycle I to 2.64 (good) in cycle II. The highest improvement occurred in elaboration and flexibility indicators, while originality improved but remained in the fair category. These findings indicate that the integration of context-based digital media with the PBL model and reflective practices such as lesson study can gradually and significantly improve students' creative thinking skills.
Learning Cycle 5E through Interactive Simulator to Improve Understanding of Molecular shapes and Chemistry Identity Pitaloka, Dinda Ayu; Muntholib, Muntholib; Dasianto, Dasianto
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.15842

Abstract

This study aims to improve students understanding of concepts and chemistry identity in molecular shape material through the application of the learning cycle 5E (LC 5E) model assisted by interactive digital simulator media. The research method used is classroom action research (CAR) with the Kemmis and Taggart model. The model has four stages, namely planning, action, observation, and reflection. The subjects in this study were 32 students from class X-3 SMA Brawijaya Smart School in the 2024/2025 academic year. The data obtained were analyzed descriptively. Based on the results of the study, it is known that in cycle I, the application of LC 5E assisted by interactive digital simulator media has not been able to improve understanding of molecular shapes and the percentage increase in students' chemistry identity is low. Therefore, improvements were made in cycle II referring to the results of the reflection, there was an increase in concept understanding from 68% to 82% with classical completeness reaching 81%. In addition, the n-gain value of 71.8% was obtained, indicating that the application of the LC 5E model assisted by interactive digital simulator media was quite effective in improving students' concept understanding on molecular shape material. There was also an increase in students' chemistry identity, especially related to the indicators of mastery experiences and verbal persuasion, 57% and 50% respectively. Thus, it can be concluded that through the application of the 5E learning cycle model assisted by interactive digital simulator media on the material of molecular shapes is effective enough to improve students' concept understanding and chemistry identity.

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