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JOURNAL LA MEDIHEALTICO
Published by Newinera Publisher
ISSN : 27211215     EISSN : 27211231     DOI : 10.37899/journallamedihealtico.v6i2.1959
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Journal La Medihealtico is peer reviewed, open access Academic and Research Journal which publishes Original Research Articles, Review Article, Case Report editorial comments etc. in all fields of medical sciences and health sciences including Health Care Delivery, Health Care Research, Epidemiology, Medical Care, Nursing, Nursing Education, Neonatal nurse, Home Health Nursing Community and Homecare, Information Technology in Nursing, Occupational Health and Safety, Midwifery, Health Care Administration, Hospital Science and Management, Innovations in Patient Care, Public Health, Health Psychology, Social Health, Physical health, Quaternary Care, Secondary Care, Veterinary Nursing, Medical Sciences and Pharmaceutical Sciences, Hospital and Clinical Pharmacy, Pathology, Physiotherapy & Rehabilitation, Ergonomics, Food and Nutrition, Veterinary Medicines.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 466 Documents
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Determination of Total Flavonoid Content of Raru Bark Extract: Cotylelobium Melanoxylon Pierre at Various Methanol Concentrations and Antibacterial Activity Against Staphylococcus Hazizah, Mautia; Ridwanto, Ridwanto; Daulay, Ani Sartika
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1949

Abstract

Raru bark (Cotylelobium melanoxylon (Hook.f) Pierre) is a plant with antidiabetic properties. Raru bark plants contain flavonoids, saponins, and tannins. The purpose of this study was to determine the class of secondary metabolites contained in the sample, determine flavonoid levels, and determine antibacterial activity against Staphylococcus aureus bacteria. This research includes processing samples made simplisia, then extracted and thickened using rotary evaporatory. Simplisia was tested for phytochemical screening to determine the content of metabolite compounds, in addition to testing its characteristics. The next test was the determination of total flavonoid content using UV-Vis spectrophotometry. Followed by testing antibacterial activity against Staphylococcus aureus. The results of phytochemical screening obtained flavonoids, tannins, and saponins. Flavonoid levels were 42.4308 ± 2.4739 mgQE/g; 38.1813 ± 1.5799mgQE/g; and 23.8153 ± 3.049276 mgQE/g, respectively. In testing antibacterial activity using concentrations of 10%, 40%, 70%, and 100%, and the highest concentration is found at a concentration of 100% which is 19.83mm.
The Effect of Health Promotion about HIV/AIDS on Adolescents’ Knowledge Tatisina, Putri Nafa Cindi; Sembiring, Lisma Natalia Br; Nasrianti, Nasrianti; Said, Fathia Inaya; Rainuny, Yance R.
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1959

Abstract

HIV/AIDS is a disease caused by a virus and can result in AIDS if not treated immediately. One factor that can overcome the transmission of HIV/AIDS is knowledge. Knowledge about HIV/AIDS is very much needed in preventing HIV/AIDS. Objective: To determine the effect of health promotion about HIV/AIDS on the knowledge of adolescents at Kaureh State High School. The study used a pre-experimental design with one group pretest posttest, a random sampling technique, a population of students in grades X and XI with a sample size of 52 respondents using a questionnaire and analyzed using the Wilcoxon test. The results obtained knowledge before health promotion was 56.6% and adolescent knowledge after health promotion was 84.3% there was an increase of 27.8% And the results of the Wilcoxon test with a value of -6.208 with a p-value of 0.000 with a significance of 0.05%. A The results show that there is an effect of health promotion about HIV/AIDS on the knowledge of adolescents at Kaureh State High School. Suggestion: Researchers expect that health promotion will be carried out continuously in collaboration with health services and it is hoped that adolescents will seek information about health from various media.
Relationship between Hemodialysis Duration, Hemoglobin, and Creatinine of Hemodialysis Erythropoietin Vaccinated Patients with Covid-19 Munuarti Muhawia; Ramatillah, Diana Laila; Sulaiman, Syed Azhar Syed
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1960

Abstract

Chronic Kidney Disease (CKD) is an abnormality of kidney function and structure, where the glomerular filtration rate is less than 60 mL/min/1.73 m² and kidney damage lasts more than 3 months. The purpose of the study was to clarify the relationship between the length of hemodialysis with Hemoglobin and Creatinine in Hemodialysis patients. The research design used was prospective and retrospective cohort. Retrospective for the period January 2022-January 2023, while for the prospective period February-April 2024. The sample size in this study using convinienvce sampling technique was 259. The results of the study showed that there was a significant relationship between the length of hemodialysis with hemoglobin and creatinine levels with a P-value of 0.001 <0.05.
Nebulized Dexmedetomidine to Reduce Delirium after General Anesthesia Sevoflurane Inhalation in Preschool Children Undergoing Elective Surgery Wongkar, Jimmy; Kurniyanta, I Putu; Suarjaya, I Putu Pramana; Tjokorda Gde Agung Senapathi; Widnyana, I Made Gede
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1965

Abstract

Surgery in children remains a major challenge, particularly due to complications such as post-anesthetic delirium, with an incidence rate of up to 80%, especially in preschool-aged children when sevoflurane is the primary agent. Nebulized dexmedetomidine has been shown to reduce the incidence of post-anesthetic delirium with minimal risk of side effects. This study aims to evaluate the effectiveness of nebulized dexmedetomidine in reducing the incidence of post-anesthetic delirium in preschool-aged children undergoing elective surgery, as part of enhancing recovery after pediatric surgery (ERAPS). This research was a double-blind, randomized controlled trial, involving 72 pediatric patients aged 2–6 years undergoing elective surgery under general anesthesia with sevoflurane. Subjects were randomly divided into two groups; Treatment group receiving nebulized dexmedetomidine 2 mcg/kg (n=36) and Control group receiving nebulized normal saline (n=36). The primary outcome was the incidence of delirium during recovery at 15, 30, 60, and 120 minutes, assessed using the Pediatric Anesthesia Emergence Delirium (PAED) Scale. Statistical analysis revealed a significantly lower incidence of post-anesthetic delirium in the nebulized dexmedetomidine group (19.4%) compared to the control group (52.8%) at 15, 30, and 60 minutes (p<0.05), with a reduction in proportion by 33.4% (p=0.003). Relative risk analysis (RR = 0.427, 95% CI: 0.218–0.835; PF = 0.631) demonstrated that dexmedetomidine provides protective effects and significantly reduces the incidence of post-anesthetic delirium in preschool-aged children undergoing elective surgery with sevoflurane inhalational anesthesia. No side effects requiring intervention were observed during this study.
Comparison of Inflammation, Pain, and Recovery in Colorectal Cancer Patients Undergoing Surgery with General Anesthesia and Combined Epidural Kenzi, Ignatio Armando; Hartawan, IGAG Utara; Sidemen, IGP Sukrana; Agung Senapathi, Tjokorda Gde; Gede Widnyana, I Made
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.2002

Abstract

Colorectal cancer has a high incidence and mortality rate. Surgery can increase the cytokine IL-6 which triggers inflammation and metastasis. The combination of general and epidural anesthesia has the potential to suppress IL-6, improve the tumor microenvironment, provide analgesia and improve postoperative recovery. To compare the effectiveness of postoperative analgesia quality in colorectal cancer patients receiving general anesthesia with combined epidural anesthesia. The single blind RCT study involved 44 patients who underwent surgery on colorectal cancer at Prof. Ngoerah Hospital. The study subjects were divided into two groups, group K who received general anesthesia and group P who received general anesthesia combined with epidural anesthesia. Patients' IL-6 will be evaluated preoperatively and 6 hours postoperatively. VAS and QOR-15 will be assessed 24 hours postoperatively. Of the 44 patients analyzed, the combined general anesthesia with epidural anesthesia group showed a significantly lower difference in IL-6 levels compared to the general anesthesia alone group of -14.69 [95% CI, p = <0.001]. The 24-hour postoperative VAS score was significantly lower than conventional general anesthesia, both in stationary and mobile conditions. In postoperative recovery, it was found that conventional general anesthesia combined with epdiural anesthesia gave greater QOR-15 results compared to conventional general anesthesia. General anesthesia combined with epidural anesthesia in colorectal cancer patients undergoing surgery can provide a lower difference in IL-6, lower VAS and higher QOR-15 postoperative satisfaction than the general anesthesia group.
Relationships between Clinical Outcomes of Coronary Heart Disease of Covid-19 Vaccinated Patients with Hypertension Susika, Lia; Ramatillah, Diana Laila; Elnaem, Mohamad
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.2004

Abstract

The effects of COVID-19 vaccination on conventional cardiovascular risk rankings for heart disease patients after inoculation need further investigation especially within Southeast Asian medical settings. The research explored hypertension effects on clinical results in CHD patients after receiving COVID-19 vaccinations at a Jakarta referral hospital in Indonesia. Research investigators conducted an observational cohort study by gathering retrospective and prospective data from January 2022 until May 2024. The clinical investigation evaluated 110 vaccinated patients who had CHD while examining population characteristics, blood pressure status, and their ultimate outcomes between survival and fatal termination. The research included statistical methods that combined Chi-square and Fisher's exact tests for categorical data analysis along with t-tests for age analysis, one-way ANOVA for subgroup analysis, Pearson correlation and binary logistic regression.. Out of the 110 patients screened for hypertension the condition was observed in 93.6%. Among hypertensive patients survival rates reached 91.3% whereas non-hypertensive patients demonstrated survival rates of 57.1% (p = 0.027). Age proved significant as a predictor of mortality and recovery duration through continuous analysis (p = 0.035; β = 0.42, p = 0.002) even though results were non-significant when patients were grouped as <60 and ≥60 years (p = 1.000). The analysis from logistic regression showed that hypertension worked as a positive predictor for patient survival with an OR of 5.33 (95% CI: 1.02–27.79) and p = 0.047. The vaccine acts as an acute disease protector yet changes but does not completely eliminate existing cardiovascular disease susceptibilities.
Etiology, Clinical Symptoms, and Risk Factors of Oculomotor Nerve Paralysis Ruslan, Riswanto; Amir, Suliati P.; Arsal, Muh. Yasin
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.2014

Abstract

The third cranial nerve, also known as the oculomotor nerve, consists of two main components: the external parasympathetic fibers that innervate the ciliary muscles and the sphincter pupillae, and the deep somatic fibers that control the levator palpebrae superioris and four extraocular muscles. Oculomotor nerve palsy has multiple etiologies and can indicate severe underlying pathology. Damage to this nerve results in characteristic symptoms such as ptosis, diplopia, restricted eye movement, and diminished or absent pupillary light reflex. This study aims to evaluate the clinical characteristics of oculomotor nerve paralysis based on its etiology, age distribution, gender prevalence, and associated risk factors. This study employs a literature review using a narrative review design. Data were collected from various indexed and accredited electronic sources such as Scopus, SINTA, DOAJ, SpringerLink, Cochrane, Biomed, Portal Garuda, Google Scholar, Elsevier/Clinical Key, Gale, PubMed, and other relevant databases. A total of 13 relevant articles were identified for this narrative review. The findings indicate that vascular abnormalities, including microvascular ischemia, aneurysms, and subarachnoid hemorrhages, are the most frequent causes of oculomotor nerve paralysis. The most commonly reported symptoms among affected patients are ptosis and diplopia. The condition is most prevalent in individuals aged 51-60 years, and women are more susceptible to oculomotor nerve paralysis than men. The most frequent cause of oculomotor nerve paralysis is an aneurysm of the posterior communicating artery. This condition predominantly affects individuals aged 51-60 years and is more common in women.
The Influence Social Support on Self-Efficacy and Quality of Life in Breast Cancer Patients Farhan, Ulfa Fadhila; Nursal, Dien Gusta Anggraini; Semiarty, Rima
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.2017

Abstract

The world-wide morbidity and mortality statistics indicate breast cancer holds its position as one of the leading diseases which affects patient psychology and social life in addition to causing physical harm. The medical interventions for disease control meet limited needs because patients' quality of life during and following chemotherapy strongly depends on their psychosocial factors especially social support and self-efficacy. The research analyzed how social support affects self-efficacy and quality of life in breast cancer patients receiving chemotherapy through self-efficacy as a possible mediator. The research design involved 95 breast cancer patients enrolled in chemotherapy treatment at Dr. M. Djamil Padang General Hospital. Consecutive sampling was used. The research data collection involved structured questionnaires followed by a Statistical Equation Modeling analysis through SmartPLS 4.0. Research examined direct along with indirect consequences through analyses which measured model explanatory capability. The research showed a strong positive link between social support leading patients to enhance self-efficacy (path coefficient = 0.922; p < 0.001) while still showing a moderate positive relation toward quality of life (path coefficient = 0.505; p < 0.001). The influence of self-efficacy on quality of life reached 0.499 significance (p < 0.001) with social support acting as a mediating factor (indirect effect = 0.460; p < 0.001). The research model established that psychosocial variables explained 85% and 80.5% of variance in patient outcomes for self-efficacy and quality of life respectively.
A Literature Review: The Relationship between Decreased Hemoglobin Levels or Anemia and Acute Myocardial Infarction Arkam, Jihan Raihanah; Wisudawan, Wisudawan; Rajab, Risna
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.2031

Abstract

Coronary heart disease (CHD) remains the leading cause of cardiovascular disease, with an estimated contribution to 36% of global mortality by 2020. Acute myocardial infarction (AMI) arises due to an imbalance between myocardial oxygen supply and demand. Anemia exacerbates myocardial ischemia by reducing blood oxygen levels and increasing myocardial oxygen consumption. This study aims to examine the relationship between decreased hemoglobin levels or anemia and AMI patients. This literature review employed a systematic search strategy using the keywords Relationship, Hemoglobin Levels, Anemia, and Acute Myocardial Infarction in both Indonesian and English. Searches were conducted across accredited electronic databases indexed in SINTA, such as Biomed Central, Garuda Portal, Google Scholar, Elsevier/Clinical Key, PubMed, and other relevant academic sources. Findings indicate that anemia influences the prognosis of AMI, although differing perspectives persist within the literature. Further research is required to comprehensively evaluate the impact of anemia on AMI patients and to determine the optimal management strategies for improving clinical outcomes.
Analysis of Waiting Time for Outpatient Services at dr Rasidin Padang Regional Hospital Sari, Fitri Yunita; Rasyid, Rosfita; Firdawati, Firdawati
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.2038

Abstract

Outpatient waiting periods extended beyond regulatory standards create major problems for hospital service quality because they damage patient satisfaction while also decreasing system performance and affecting institutional public perception. The regulatory standards regarding outpatient waiting times of ≤ 60 minutes were not reflected in the initial survey results at RSUD dr. Rasidin Padang since durations exceeded these limits. Research conducted a mixed-methods sequential explanatory design to explore the elements that lengthen outpatient delays at RSUD dr. Rasidin Padang. A total of 107 outpatients participated using proportional accidental sampling to provide quantitative data while qualitative information came from 14 key informants through semi-structured interviews and 8 participants in a Focus Group Discussion. Research data showed that 76.6% of patients waited for above 60 minutes and the entire process took on average 130 minutes. Insufficient human resources dedicated to medical records and registration combined with specialist doctor indiscipline in exam scheduling together with inadequate facilities that included broken fingerprint devices and insufficient operational computers caused this delay in patient examination start times. The qualitative findings show that Standard Operating Procedures (SOPs) remained in place yet inconsistent execution due to fragmented leadership functions degraded efficiency in services. Insured BPJS patients had to bear excessive administrative procedures that generated extended waiting times than what general patients received.

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