cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Farhamzah
Contact Email
farhamzah@ubpkarawang.ac.id
Phone
+6281380007942
Journal Mail Official
buanafarma@ubpkarawang.ac.id
Editorial Address
JL. H.S. Ronggowaluyo Telukjambe Timur Karawang 41361
Location
Kab. karawang,
Jawa barat
INDONESIA
Jurnal Buana Farma
Published by Universitas Buana Perjuangan Karawang
ISSN : -     EISSN : 27972100     DOI : 10.36805
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
The major focus of Jurnal Buana Farma is to publish articles in the area of Experimental Pharmacology, Clinical Pharmacy, Pharmaceutical Technology, Pharmacoeconomy, Pharmacognosy, Pharmaceutical chemistry.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 253 Documents
 19   20   21   22   23 
AKTIVITAS ANTIJAMUR EKSTRAK ETANOL DAUN KARI TERHADAP Candida albicans ATCC 14053 Sari, Putri Eka; Chandra, Pra Panca Bayu; Lisnawati, Nia; Ami, Neng
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1400

Abstract

Medicinal plants are recognized as valuable sources of secondary metabolites with therapeutic potential. Candidiasis caused by Candida albicans is a common health problem in tropical regions. The prolonged use of synthetic antifungal agents may lead to resistance, highlighting the need for effective natural alternatives. Curry leaves (Murraya koenigii (L) Spreng) are known to contain flavonoids and alkaloids with potential antifungal activity. This study aimed to evaluate the antifungal activity of the 96% ethanol extract of curry leaves against Candida albicans ATCC 14503. The extract was prepared by maceration using 96% ethanol as the solvent. Phytochemical screening revealed the presence of flavonoids and saponins. The antifungal activity was tested using the disc diffusion method at concentrations of 6,25%, 12,5%, 25%, and 50%. Ketoconazole was used as positive control, while 96% ethanol served as a negative control. The test was performed in triplicate, and the inhibition zones were measured and averaged. The results showed that the 96% ethanol extract of curry leaves at all tested concentrations did not exhibited antifungal activity against C. albicans as indicated by the absence of inhibition zones on the media. It can be concluded that the extract, under the given conditions, was not effective in inhibiting fungal growth. This suggests that the extraction method and tested concentrations may not have been sufficient to isolate or concentrate the active compounds. Further studies using alternative extraction techniques, higher concentrations or isolated compounds are needed to better evaluate the antifungal potential of M. koenigii.
ARTIKEL REVIEW : AKTIVITAS ANTIOKSIDAN BUNGA MAWAR MERAH (Rosa damascene Mill.) Oktavia, Dian Ayu; Aristia, Bella Fevi; Prajawanti, Kadeq Novita
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1403

Abstract

Red rose (Rosa damascena Mill.) is an ornamental plant that is rich in bioactive compounds such as flavonoids, anthocyanins, phenols, vitamin C, tannins, and saponins that function as natural antioxidants. The purpose of this article is to review research results related to the antioxidant activity of red rose flowers in various dosage forms and extraction methods. This review was conducted through a literature review of 10 selected scientific articles in the range of 2015-2025 using the exclusion and inclusion method. The results showed that most of the red rose flower extracts showed very strong antioxidant activity, characterized by IC₅₀ values < 50 ppm, even in some studies reaching < 20 µg/mL. Antioxidant activity is influenced by the type of solvent, temperature and processing time, as well as the combination of ingredients such as bengkoang or mint leaves. Polar extracts such as ethanol and methanol tend to give the best results, while high temperature treatment and long heating times tend to reduce the effectiveness of active compounds. Thus, rose red flowers have great potential as a source of natural antioxidants that can be utilized in functional food, cosmetic, and pharmaceutical products.
POTENSI ANTIINFLAMASI SENYAWA BIOAKTIF DARI SYZYGIUM MYRTIFOLIUM: STUDI MOLECULAR DOCKING BERTARGET COX-2 Putri, Refsya Azanti; Saputra, Muhammad Yogi; Enggelina, Nia Natalia; Windasari, Liska; Ivansyah, Atthar Luqman
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1404

Abstract

Chronic inflammation contributes significantly to various degenerative diseases, with Cyclooxygenase-2 (COX-2) being a central target for anti-inflammatory drug development. Syzygium myrtifolium, a native Indonesian plant, is known to contain a variety of bioactive compounds with pharmacological potential. This study aims to investigate the anti-inflammatory activity of S. myrtifolium active compounds on COX-2 using a molecular docking approach. The tested compounds include avicularin, betulinic acid, ursolic acid, and two flavanones modeled and docked against the COX-2 protein (PDB ID: 5F19) using YASARA. Docking simulations were performed using YASARA software via a blind docking method and visualized through Discovery Studio. The results revealed that four compounds demonstrated stronger binding affinity than celecoxib, with (2S)-7-Hydroxy-5-methoxy-6,8-dimethylflavanone showing the most stable interaction with 9.0450 kcal/mol binding energy. Toxicity prediction suggests these compounds are generally safe based on LD50 values and toxicity class. These findings support the potential of S. myrtifolium as a natural source of COX-2 inhibitors.
AKTIVITAS ANTICAPLAK SEDIAAN SPRAY YANG MENGANDUNG MINYAK ROSEMARY,BERGAMOT DAN CUKA APEL Ath-Thaariq, Affan Aufar; Prasetyo, Bayu Febram; Supriyono
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1408

Abstract

Apple cider vinegar and rosemary oil have an acaricidal effect on R. sanguineus ticks. Both ingredients offer health benefits. This study aimed to observe the effect of a spray preparation containing apple cider vinegar and rosemary oil at various concentrations on the mortality of R. sanguineus ticks. The study was conducted from February 2025 to April 2025. It used 75 R. sanguineus ticks, divided into 5 groups, with each group having three repetitions. K1, the negative control, was treated with pure distilled water. K2, the positive control, was treated with Fipronil 3% (Frontline brand). K3 was given bergamot oil 5%, rosemary oil 10%, and apple cider vinegar 5%. K4 was given bergamot oil 5%, rosemary oil 10%, and apple cider vinegar 10%. K5 was given bergamot oil 5%, rosemary oil 10%, and apple cider vinegar 15%. Each treatment group consisted of 5 ticks. Observations were made at 30, 60, 90, 120, and 180 minutes post-contact. The results showed that the group treated with bergamot oil 5%, rosemary oil 10%, and apple cider vinegar 15% achieved a Lethal Time 50 (LT50) at 106 minutes. The conclusion indicates that apple cider vinegar at a concentration of 15% required the least amount of time to kill the ticks
UJI AKTIVITAS ANTIDIABETES FRAKSI ETIL ASETAT DAUN PEPAYA (Carica papaya L.)TERHADAP TIKUS JANTAN WISTAR (Rattus norvegicus) Neswita, Elfia; Naldi, Jefri; Kinanti, Dara; Nasution, Halimah Raina; Pramudita, Rufina; Nurasni
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1375

Abstract

Diabetes mellitus is a serious chronic disease that occurs when the pancreas does not produce sufficient insulin or when the body is unable to effectively utilize the insulin produced. Papaya leaves (Carica papaya L.) have been reported to possess potential antidiabetic properties. The novelty of this study lies in evaluating the antidiabetic activity of the ethyl acetate fraction of papaya leaves in male Wistar rats. This study aimed to determine the antidiabetic activity of the ethyl acetate fraction of papaya leaves in alloxan-induced male Wistar rats. Papaya leaf simplicia powder was extracted using the maceration method with 70% ethanol as the solvent. The concentrated extract was subsequently fractionated using ethanol–water, n-hexane, and ethyl acetate. Antidiabetic activity was evaluated using alloxan induction at a dose of 150 mg/kg body weight. Blood glucose levels were measured before alloxan induction to determine baseline values, two days after induction to confirm hyperglycemia, and every seven days for 14 days of treatment to assess changes in glucose levels. Phytochemical screening revealed that the ethyl acetate fraction contained alkaloids, flavonoids, and saponins. The results showed that the ethyl acetate fraction at a dose of 300 mg/kg body weight exhibited the highest antidiabetic activity, with a 64% reduction in blood glucose levels, slightly higher than the positive control, which showed a 63% reduction. In conclusion, the ethyl acetate fraction of papaya leaves at a dose of 300 mg/kg body weight demonstrates promising antidiabetic potential, likely attributable to its bioactive compounds.
ARTICLE REVIEW : TINJAUAN DAMPAK PENERAPAN TELEFARMASI TERHADAP PENINGKATAN PELAYANAN KESEHATAN PASIEN DI APOTEK Rambe, Sahrum; Suryani, Suryani
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1419

Abstract

The growing demand for efficient and accessible healthcare services especially in the context of geographical challenges and the post-pandemic environment has driven the development of innovations such as telepharmacy. Telepharmacy, as a subset of telemedicine, expands access to pharmaceutical services through communication technology and represents a significant breakthrough in healthcare delivery by supporting pharmacists in providing pharmaceutical care information. Although the adoption of telepharmacy in Indonesia is still progressing, this article aims to review its impact on improving the quality of healthcare services, particularly within the Indonesian context. Relevant literature on telepharmacy implementation in Indonesia was retrieved from Google Scholar, PubMed, and other academic platforms, focusing on publications from 2015 to 2025. The purpose of evaluating these articles was to ensure that their content met established standards. Nine articles discussing the use of telepharmacy which has been increasingly adopted in healthcare settings, especially in community pharmacies were selected for this review. Findings from the literature indicate that telepharmacy can enhance healthcare quality by reducing costs, improving the efficiency of pharmaceutical services, and decreasing prescription errors. As an alternative approach to expanding service coverage and reaching rural areas, telepharmacy has also been widely adopted in pharmacies, enabling pharmacists to contribute more effectively to improving medication use.
HUBUNGAN TINGKAT KEPATUHAN DAN PENGETAHUAN PASIEN TERHADAP PENGOBATAN TUBERKULOSIS PARU DI PUSKESMAS MEKARMUKTI TAHUN 2025 Evellia Priastuti; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata; Marselina, Marselina
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1506

Abstract

Tuberculosis (TB) is a global and national public health problem, as well as an important indicator of achieving the Sustainable Development Goals (SDGs). Indonesia continues to face a high burden of tuberculosis, ranking second after India with millions of cases each year. Treatment success rates have not yet reached the national target, while West Java, including Bekasi Regency, records the highest cases. At Mekarmukti Health Center, in 2016 there were 81 new smear-positive pulmonary TB cases and 16 old cases, with a total of 97 patients, highlighting the importance of sustainable control at primary health services. This study aims to analyze the relationship between knowledge and treatment adherence among TB patients at Mekarmukti Health Center. This quantitative research employed an observational method with a total sampling technique involving 95 respondents. The instrument used was a questionnaire, and data analysis was conducted using the chi-square test. The results showed a relationship between age and knowledge (p=0.000), education and knowledge (p=0.041), as well as treatment category and knowledge (p=0.028). Age was also associated with adherence (p=0.002). However, knowledge was not significantly associated with adherence (p=0.337).
FORMULASI DAN EVALUASI GEL EKSTRAK DAUN TAHI BELALANG PADA LUKA BAKAR KELINCI Lende, Yulianus Erman; Hidayat, Rahmat; Listyani, Tiara Ajeng
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1519

Abstract

Burn wounds are a common health issue that requires effective management. This study explores the potential of tahi belalang leaf extract (Chromolaena odorata L.) as a healing agent for burn wounds, with bioactive compounds such as flavonoids, saponins, tannins, and alkaloids that possess anti-inflammatory, antioxidant, and anti-allergic properties. The main objective is to formulate and evaluate the gel preparation of tahi belalang leaf extract as an alternative topical treatment. The research method involves plant determination, preparation, standardization of simplicia, extraction, and phytochemical screening to identify active compounds. Subsequently, gel formulations were created with varying concentrations of extract (5%, 10%, 15%) and the physical quality of the preparations was evaluated (organoleptic, homogeneity, pH, viscosity, spreadability, adhesion, irritation, and hedonic). The effectiveness of burn wound healing was tested in vivo on male rabbits, comparing the gel formula with a negative control (gel base) and a positive control (Bioplacenton®), with daily wound diameter measurements and statistical analysis using SPSS. The results showed that the gel containing 15% tahi belalang leaf extract (F3) was the most effective formulation in accelerating the healing of second-degree burn wounds in male rabbits. The presence of flavonoids, alkaloids, tannins, and saponins contributed anti-inflammatory, antioxidant, and antibacterial effects that supported tissue regeneration. Based on the ANOVA significance value of 0.028, there was a statistically significant difference among the treatment groups of the formulations.
HUBUNGAN PENGETAHUAN PASIEN DENGAN KEPATUHAN ANTIHIPERTENSI DAN LUARAN KLINIS Dewi, Antih Puspita; Marselina, Marselina; Adiwisastra, Nuzul Gyanata; Dewi, Masita Sari
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1521

Abstract

Hypertension is a highly prevalent chronic disease in Indonesia. Patients’ knowledge is considered a key factor in improving adherence, but its association with blood pressure control remains inconsistent. To evaluate the relationship between patients’ knowledge, antihypertensive medication adherence, and blood pressure control among hypertensive patients at Cikarang Primary Health Center. This cross-sectional analytic study involved 51 hypertensive patients who had received therapy for at least three months. Instruments included the Hypertension Knowledge-Level Scale (HK-LS) to assess knowledge, the Morisky Medication Adherence Scale (MMAS-8) to measure adherence, and medical records to determine blood pressure control. Data were analyzed using Chi-Square and Pearson correlation tests. Most respondents demonstrated high knowledge (70.59%), yet nearly half showed low adherence (47.06%). Knowledge was significantly associated with adherence (p=0.039), while no significant relationship was found between knowledge and blood pressure control (p=0.733). Higher knowledge improves medication adherence but does not necessarily lead to optimal blood pressure control. Comprehensive strategies beyond knowledge enhancement are needed for effective hypertension management.
HUBUNGAN KEPATUHAN PENGOBATAN ANTIHIPERTENSI DENGAN RISIKO KARDIOVASKULAR PADA PASIEN HIPERTENSI PUSKESMAS TELAGA MURNI Antarini, Destya; Marselina, Marselina; Adiwisastra, Nuzul Gyanata; Suparmi, Ninik
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1525

Abstract

Hypertension is a major risk factor for cardiovascular disease, with its prevalence continuously increasing in the community. Adherence to antihypertensive therapy plays a crucial role in controlling blood pressure and preventing cardiovascular complications. However, evidence on the relationship between medication adherence and cardiovascular risk remains inconsistent, especially in primary healthcare settings. This study was conducted at Telaga Murni Primary Health Center – Cikarang, where hypertension is among the ten most common diseases. The study aimed to determine the relationship between adherence to antihypertensive therapy and cardiovascular risk among hypertensive patients. This research employed a quantitative analytic design with a cross-sectional approach involving 85 hypertensive patients selected through purposive sampling. Adherence was assessed using the Medication Adherence Report Scale (MARS-5) and Medication Possession Ratio (MPR), while cardiovascular risk was evaluated using the ASCVD Risk Estimator. Data were analyzed using the Chi-Square test, linearity test, and Odds Ratio calculation. The results showed that most patients were adherent (MARS-5 = 91.8%; MPR = 72.9%) and had low cardiovascular risk (52.9%). There was a significant relationship between adherence and cardiovascular risk for both MARS-5 (p=0.041) and MPR (p=0.049), although linear correlation was observed only in MARS-5 (p=0.012). Adherent patients had a higher likelihood of having a lower cardiovascular risk compared to non-adherent patients. In conclusion, adherence to antihypertensive therapy was associated with cardiovascular risk among hypertensive patients. Continuous education and regular monitoring are essential to maintain patient adherence and prevent increased cardiovascular risk.

Page 21 of 26 | Total Record : 253

 19   20   21   22   23 

Filter by Year

2021 2026


Reset
Filter By Issues
All Issue Vol 6 No 1 (2026): Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 4 No. 1 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 4 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 3 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 2 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 3 No. 1 (2023): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 4 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 3 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 2 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 2 No. 1 (2022): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 4 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 3 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 2 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi Vol. 1 No. 1 (2021): Jurnal Buana Farma : Jurnal Ilmiah Farmasi More Issue