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JIFI (Jurnal Ilmiah Farmasi Imelda)
Published by Universitas Imelda Medan
ISSN : 26553147     EISSN : 25977164     DOI : https://doi.org/10.52943/jifarmasi.v5i1.623
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
JIFI (Imelda Pharmacy Scientific Journal) Imelda Imelda College of Health Sciences (STIKes) which is now Imelda University Medan received related articles: 1. Clinical Community Of Pharmacy 2. Pharmaceutical Technology 3. Pharmacy Management 4. Herbal medicines and Chemistry 5. Biology & Pharmacology JIFI (Jurnal Scientific Pharmacy Imelda) also accepts all writings with various disciplines on the condition that the core points remain in the path and scope of pharmaceutical science.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 119 Documents
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UJI POTENSI ANTITUBERKULOSIS EKSTRAK n-HEKSAN DAN EKSTRAK ETANOL DAUN RIMBANG (Solanum torvum Sw.) SECARA IN VITRO Harianti, Evi; Fatimah, Cut; Gunawan, Muhammad; Lala, Andi
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 1 (2024): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i1.1772

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis which still affects many Indonesians and causes death. Currently, many people are resistant to treating tuberculosis using synthetic chemicals, so many sufferers find it difficult to recover, while the discovery of new drugs is still rare, therefore we need drugs made from natural ingredients that have been used by the community to treat coughs with phlegm and blood, which is one of the Symptoms of tuberculosis include rimbang leaves (Solanum torvum Sw.). Therefore, researchers conducted antituberculosis potential tests with rimbang leaf extract (Solanum torvum Sw.) with the aim of obtaining alternative medicines from plants that are rational, safe, cheap and easy to obtain. The extract was made by percolation using n-hexane followed by ethanol fractionation, then a phytochemical screening test was carried out on fresh leaves, simplicia, ethanol extract and n-hexane extract. The antituberculosis test of n-hexane extract and ethanol extract was carried out on Mycobacterium tuberculosis bacteria using the Lowenstein-Jensen method using patient sputum which was first identified using Ziehl Nielsen staining. The results of the phytochemical screening test showed that the chemical compound groups in fresh leaves, simplicia, ethanol extract and n-hexane extract, namely ethanol extract, were positive for alkaloids, flavonoids, glycosides, saponins, steroids/triterpenoids. and tannins while the n-hexane extract was positive for glycosides and steroids/triterpenoids. The antituberculosis effectiveness of ethanol extract is stronger than n-hexane extract, because in the 1st week and 2nd week the ethanol extract was able to inhibit the growth of Mycobacterium tuberculosis, while the n-hexane extract from the 1st to the 4th week did not inhibit the growth of Mycobacterium tuberculosis at all.
PENGARUH PELAYANAN KEFARMASIAN TERHADAP KEPUASAN PELANGGAN APOTEK DI WILAYAH KAMPUNG TENGAH KECAMATAN KERAMAT JATI, JAKARTA TIMUR TAHUN 2024 Sari, Dini Permata; Abidin, Zainal
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1771

Abstract

Service quality is considered a significant strategy tosatisfy the customer and encourage repeated service whichattracts loyal customers. The purpose of this study is to determine the influence of pharmaceutical services on visitor satisfactionin community pharmacies Kampung Tengah, Keramat Jati District, East Jakarta. The method of this research is descriptive research using quantitative techniques through questionnaires conducted as part of a survey. The population of this study is visitors in community pharmacies in Kampung Tengah, Keramat Jati District, East Jakarta in May 2024. Samples taken from the population used purposive sampling. The results of the calculation using the Slovin technique formula are known that the required sample is 189 respondents. The data analysis technique used a univariate analysis and a bivariate analysis. Based on the results of the study, it shows that there is a strong and significant relationship between the assurance provided by the service provider and the level of visitor satisfaction. There is a significant relationship between empathy and visitor satisfaction. Response time and visitor pleasure are significantly correlated. Visitor pleasure and consistency are significantly correlated. Visitor pleasure and tangible facilities are significantly correlated. The conclusion of the study shows that the profile of pharmaceutical services in apotek is quite good, as indicated by the presence of pharmacists every day at the pharmacy and the active role of pharmacists in pharmaceutical services at the apotek.
EVALUASI INTERAKSI OBAT ANTIRETROVIRAL PASIEN HIV-AIDS RAWAT INAP DI RUMAH SAKIT UMUM IMELDA PEKERJA INDONESIA MEDAN Auliafendri, Novycha; Sinaga, Alex Handani; Hasibuan, Nabila Nazwa
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1830

Abstract

HIV/AIDS merupakan masalah kesehatan global dengan tingkat kematian yang tinggi, meskipun terapi antiretroviral (ARV) terbukti efektif dalam menghambat perkembangan virus. Namun, interaksi antara obat ARV dan obat lain yang diberikan sering kali mempengaruhi efektivitas terapi serta meningkatkan risiko efek samping. Oleh karena itu, evaluasi interaksi obat ARV menjadi penting untuk memastikan keamanan dan efektivitas terapi. Penelitian ini bertujuan untuk melibatkan interaksi obat antiretroviral secara farmasetik, farmakokinetik, dan farmakodinamik pada pasien rawat inap dengan HIV/AIDS di RSU IPI Medan. Penelitian ini menggunakan metode observasional retrospektif dengan mengumpulkan data dari rekam medis pasien HIV/AIDS yang dirawat di RSU IPI Medan pada periode Januari–Desember 2023. Data yang dianalisis meliputi karakteristik pasien, jenis obat ARV yang digunakan, serta potensi interaksi obat berdasarkan mekanisme farmakokinetik dan farmakodinamik. Dari penelitian menunjukkan bahwa kombinasi obat antiretroviral yang paling banyak digunakan adalah tenofovir (TDF), lamivudin (3TC), dan dolutegravir (DTG), yang digunakan oleh 40 pasien (57%). Dari total tersebut, terdapat 82 kasus interaksi obat (97,6%), dengan tingkat keparahan interaksi sedang sebanyak 69%, mayor 24%, dan minor 7%. Interaksi dengan mekanisme farmakokinetik mencapai 68%, farmakodinamik sebesar 32% dan interaksi secara farmasetik tidak ada. Penelitian ini menekankan perlunya pemantauan yang lebih ketat dan kolaborasi antar tenaga kesehatan untuk meminimalkan risiko interaksi obat dalam pengobatan pasien HIV/AIDS
GAMBARAN TINGKAT PENGETAHUAN PENGGUNAAN ANTIBIOTIK PADA MAHASISWA PROGRAM STUDI D3 MANAJEMEN INFORMATIKA DAN KOMPUTERISASI AKUNTANSI UNIVERSITAS IMELDA MEDAN Samgryce Siagian, Hartika; Nasution, Dina Rahmadani; Samosir, Sri Rezeki
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1842

Abstract

Antibiotics are chemical compounds produced by a microorganism (especially produced by fungi) or produced synthetically which can be used to kill or inhibit the development of bacteria and other organisms. The use of antibiotics must be recommended by a doctor if the bacterial infection does not improve, the infection suffered is a contagious infection, and there is a risk of complications from the bacterial infection. Antibiotic resistance is a condition where bacteria become resistant to antibiotics. This occurs because the patient does not understand how to take antibiotics that have been recommended by the doctor. The aim of this research is to determine the level of knowledge of antibiotic use among students of the D3 Informatics Management and Computerized Accounting study program at Imelda University, Medan. The method used is a descriptive method using a questionnaire distributed to respondents. The sample is 50 active students from Informatics Management and Accounting Computerization Study Program. The sampling technique in this research uses the systematic Random Sampling method. Data analysis was carried out descriptively by displaying the percentage of knowledge level of 76-100% good knowledge level, 56-75% sufficient knowledge level and 0-56% poor knowledge level. The results of this research show that the description of the level of knowledge of students on the use of antibiotics in students of the third diploma study program in Informatics Management is better than Computerized Accounting, this is proven by the percentage of knowledge level of Informatics Management of 12 respondents (48%) in the sufficient category and the level of knowledge of Computerized Accounting as many as 11 respondents (44%) were in the poor category.
UJI EFEKTIVITAS EKSTRAK ETANOL BIJI BUAH PINANG MUDA (Semen Areca Catechu L.) TERHADAP JAMUR CANDIDA ALBICANS Maya Syari, Dina; Samosir, Sri Rejeki; Siagian, Hartika Samgryce; Andini, Tri
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1843

Abstract

Biji Buah Pinang Muda (Semen Areca Catechu L.) merupakan salah satu sumber pangan fungsional, dimana bijinya mengandung tanin, polifenol dan alkaloid yang berperan sebagai antioksidan, serta memiliki kegunaan antara lain untuk konsumsi, bahan industri kosmetik,dan kesehatan.Untuk mngetahui efektivitas ekstrak etanol biji buah pinang muda (Semen Areca Catechu L.) Terhadap Jamur Candida Albicans. Penelitian ini yaitu eksperimental. Ekstrak etanol biji buah pinang muda dibuat secara maserasi. Pengujian aktivitas antibakteri diuji dengan metode difusi kertas cakram dengan variasi konsentrasi 20%, 30% dan 40% serta kontrol negatifnya adalah aquadest dan kontrol positif adalah ketoconazol.Hasil skrining senyawa fitokimia menunjukkan bahwa ekstrak biji buah pinang muda mengandung flavonoid, saponin, dan alkaloid. Uji aktivitas antibakteri ekstrak biji buah pinang muda dari 3 variasi konsentrasi memiliki daya hambat yang sama dimana analisa yang menggunakan anova tidak memiliki efektivitas antijamur yang nyata dimana nilai p memiliki sig 0,029 < 0,05. Ektrak etanol biji buah pinang muda (Semen Areca Catechu L.) terbukti memiliki efektivitas Terhadap Jamur Candida Albicans.
PEMBUATAN DAN EVALUASI KARAKTERISTIK FISIK HAND AND BODY LOTION DARI KOMBINASI EKSTRAK BUNGA LAVENDER (Lavandula angustifolia Mill) DAN EKSTRAK BATANG SEREH (Cymbopogon citratus (DC) Stapf) Samosir, Sri Rezeki; Samgryce, Hartika; Husna, Miftahul
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1845

Abstract

Hand and body lotion from a combination of lavender flower extract (Lavandula angustifolia Mill) and lemongrass stems (Cymbopogon citratus (DC) Stapf) has been carried out. The research method is experimental in the laboratory with a quantitative analysis approach. The samples from this research were extracts from lavender flowers and lemongrass stems. The research stages include sample sorting, extraction, extract evaporation, making hand and body lotion and evaluating the characteristics of hand and body lotion. The extraction stage used the maceration method for 3 days with 96% ethanol solvent, the extract obtained was concentrated using a rotary evaporator. Hand and body lotion from a combination of lavender flower extract and lemongrass stems is made in 3 concentrations, namely 1%, 3% and 5% respectively. Tests evaluating the physical characteristics of the preparation include organoleptic tests, homogeneity tests, pH tests, spreadability tests, hedonic tests, irritation tests on volunteers and viscosity tests. The organoleptictest results showed that the preparation hadagreenish brown color and a smooth texture. Based on the results, it can be concluded that a combination of lavender flower extract and lemon grass stem extract can be formulated in hand and body lotion preparations. It is recommended that researchers further make other cosmetic preparations such as facial lotion from lavender flower extract and lemongrass stem extract.
PREFORMULASI: KONSENTRASI AMILUM BUAH PISANG SINGALI-NGALI (Musa Acuminata Lady Finger) SEBAGAI BAHAN PENGIKAT TERHADAP TABLET PARACETAMOL METODE GRANULASI BASAH YANG MEMENUHI PERSYARATAN FARMAKOPE Sinaga, Alex; Auliafendri , Novycha; Sabina, Fitri
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1850

Abstract

Currently, bananas can be processed and used to produce starch. Research results show that bananas have a lot of nutrients per 100 grams. There is 99 kcal of energy, 1.2 grams of protein, 0.2 grams of fat, 93% carbohydrates, 2.93% water (Shekhara Naik R et al., 2023). Because of their carbohydrate content, bananas can be made into starch. These bananas will be used as the main ingredient to make banana starch. This starch can be used in the pharmaceutical industry as an additional ingredient for making tablets because of its properties as a binder, disintegrant and filler. The aim of this research was to determine the effect of the concentration of Singali-Ngali banana starch (Musa Acuminata Colla) as a binding agent in granule evaluation tests that meet the requirements of the VI edition of the Pharmacopoeia. This research method is included in quantitative experimental research, which is carried out in the laboratory. The stages of this research started from sample preparation, making banana starch, characteristics test, carbohydrate test, pre-formulation, granule evaluation test and paracetamol tablet evaluation test from singali ngali banana binder. The results obtained from the Singali Ngali banana binder can have a positive influence with the p value 0,05 at a CL value of 95% From the conclusion, all formulas meet the requirements as binders
FORMULASI DAN UJI EFEKTIVITAS ANTIBAKTERI SEDIAAN MOUTHWASH DARI EKSTRAK DAUN KEMANGI (Ocimum x africanum L.) TERHADAP BAKTERI Staphylococcus aureus Voen-Na, Cut Dara; Wardani, Tatiana Siska; Wicahyo, Septian Maulid
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1856

Abstract

The oral cavity is susceptible to bacterial infections because it has direct exposure to the outside environment, one of which is Staphylococcus aureus, which can cause oral health problems. The use of mouthwash as an additional treatment helps maintain optimal oral hygiene. Basil leaves (Ocimum x africanum L.) contain secondary metabolite compounds that have the potential to inhibit the growth of S. aureus. This study aims to determine the physical quality test of mouthwash of basil leaf extract and test its antibacterial effectiveness against S. aureus. This research method is laboratory experimental. Basil leaf simplicia powder (Ocimum x africanum L.) is macerated with 96% ethanol. Mouthwash formulations are made in concentrations of 4%, 6%, 8%, and 10%. Testing was carried out using the disc diffusion method to assess the antibacterial effectiveness against S. aureus ATCC 25923. Physical quality tests are also carried out on mouthwash preparations. The data from the antibacterial test results were analyzed using the One-Way ANOVA method. The results showed that the mouthwash preparation formula of basil leaf extract had good physical quality in terms of organoleptics, pH, specific gravity, viscosity, and clarity. The results of the statistical test showed a significant difference in the diameter of each group (P<0.05); mouthwash preparation at F4 (10%) had an inhibitory power against S. aureus bacteria of 8.46 mm with a bacterial inhibition zone of the medium category.
UJI AKTIVITAS ANTIBAKTERI SEDIAAN MASKER GEL EKSTRAK DAUN TAPAK DARA (Catharanthus roseus (L) G. Don) TERHADAP BAKTERI Staphylococcus aureus Agustina, Isnaini; Wardani, Tatiana Siska; Luthfiyanti, Niken
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1864

Abstract

Gel masks are semi-solid preparations that serve as skincare products with benefits, such as addressing various skin problems. This study aims to conduct a physical quality test on gel masks containing tapak dara leaf extract, determine the antibacterial activity of tapak dara leaf extract and evaluate the antibacterial activity of the tapak dara leaf extract gel mask against Staphylococcus aureus ATCC 25923 bacteria. This study uses both qualitative and quantitative analysis with experimental methods. The extraction of virgin leaves is carried out using the maceration method with a 70% ethanol solvent. The extracts and preparations are made into three concentrations: 10%, 20%, and 30%. The physical quality testing of tapak dara leaf gel masks includes organoleptic evaluation, homogeneity, pH, dispersion, and drying time. The results of one-way ANOVA for pH (sig. = 0.815), dispersion (sig. = 0.695), and drying time (sig. = 0.251) showed that the significance values were greater than 0.05. Tapak dara leaf extract demonstrates antibacterial activity against Staphylococcus aureus bacteria, with inhibitory zone diameters of 3.5 mm, 7.87 mm, and 9.85 mm. The gel mask preparation of virgin palm leaf extract exhibits antibacterial activity against Staphylococcus aureus bacteria, with inhibition zone diameters of 3.67 mm, 4.77 mm, and 7.4 mm. The results of one-way ANOVA on the activity of virgin palm leaf extract against Staphylococcus aureus bacteria showed a significance value less than 0.05.
UJI MUTU FISIK SEDIAAN LIP BALM DAN KADAR TOTAL ANTOSIANIN EKSTRAK DAUN JATI (Tectonagrandislinn., F.) Lindra Putri, Jessika Ukurmehuli; Hidayat, Rahmat; Wardani, Tatiana Siska
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 2 (2025): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i2.1866

Abstract

Lip balm is a product that serves to prevent dryness of the lips by increasing moisture and protecting them from the adverse effects of the environment. In making this lip balm, Teak leaves (Tectonagrandislinn., F) are used as a natural colorant because they contain pigments, especially anthocyanins. Anthocyanins are flavonoid compounds that have antioxidant properties. This study aims to determine the total anthocyanin content in teak leaf extract and design a lip balm formulation that meets physical quality standards. In addition, the study also tested variations in concentration to find the best formulation. The type of research used with experimental methods involving physical quality tests of lip balm preparations and total anthocyanin levels of teak leaf extract.The results showed that lip balms with formula 0 (no extract), formula I (2% extract), formula II (3% extract), and formula III (4% extract) met the physical quality standards based on SNI 1-4399-1996, including in the aspects of homogeneity, adhesion, spreadability, viscosity, and pH. The total anthocyanin content in teak leaf extract was 68.298 mg/L. In addition, variations in extract concentration also affected the panelists' level of liking, where formula III with a concentration of 4% was the most preferred because it had an even composition, suitable pH, good spreadability and adhesiveness, and did not cause irritation.

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