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INDONESIA
Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 248 Documents
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INDENTIFIKASI SENYAWA EKSTRAK UMBI GARUT DAN TEPUNG IKAN LELE DUMBO MELALUI UJI FITOKIMIA SEBAGAI IMUNOSTIMULAN PADA TIKUS PUTIH YANG DI INDUKSI VAKSIN HEPATITIS B Zulkifli, Zulkifli; Jamil, Kurnian Fitri; Darmawi, Darmawi; Usman, Said
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3426

Abstract

The variety of biodiversity that grows in Indonesia makes this country the second megacenter in the world after Brazil. More than 30,000 plant species grow and 2,500 of them are medicinal plants one of them is arrowroot (Maranta arundinacea) as well as natural sources of animal wealth such as Dumbo catfish (Powder Clarias gariepinus) which is a source of protein that is needed by the body. Several researchers have also investigated the active compounds contained in the two ingredients, but differences in the environment and the maintenance process significantly affect the chemical content. This research focused on the initial phytochemical test and chemical composition of Maranta arundinacea extract and Clarias gariepinus powder extracted with 40% ethanol by maceration and hydrolysis techniques
ANALISIS KADAR KALSIUM PADA CANGKANG TELUR BEBEK (Anas platyrhynchos-domesticus) UNTUK PEMBUATAN PASTA GIGI DENGAN PEWARNA ALAMI DARI SARI DAUN PANDAN (Pandanus amaryllifolius Roxb) Dalimunthe, Agusmal; Nurbaya, Siti; Priltuis, Natanael; Ginting, Pitalokasari br
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3427

Abstract

Cangkang telur merupakan limbah rumah tangga yang dapat dimanfaatkan dalam pembuatan pasta gigi karena mengandung kalsium karbonat (CaCO3) sekitar 90 % sebagai penyusun utamanya. Daun pandan merupakan zat pewarna alami yang sering digunakan dalam kehidupan sehari-hari. Penelitian ini dilakukan dengan menentukan kandungan kalsium karbonat terlebih dahulu kemudian menentukan kadar kalsium murni dari kalsium karbonat tersebut dengan cara titrasi kompleksometri denga menggunakan EDTA untuk pembuatan pasta gigi dengan pewarna alami dari sari daun pandan.
UJI EFEKTIVITAS SEDIAAN GEL EKSTRAK BIJI KELENGKENG (Dimocarpus longan Lour.) SEBAGAI OBAT LUKA BAKAR TERHADAP MENCIT PUTIH JANTAN (Mus musculus) Sitorus, Elly; Thaib, Cut Masyithah; Suryani, Monica; Sarumaha, Vivid Angelina
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3428

Abstract

Longan seeds contain corrilagin, gallic acid, and ellagic acid compounds which have the potential as an alternative medicine for burns. This study aims to determine the effectiveness of the longan seed extract gel preparation with 3 variations of extract concentration (5%, 7.5%, and 10%) as a burning medicine against white male mice. Longan seed extract was obtained by using the maceration extraction method
RESISTENSI OBAT PADA PASIEN TUBERKULOSIS PARU DI PUSKESMAS BATU HORPAK KABUPATEN TAPANULI SELATAN Hutauruk, Dumartina; Situmorang, Manahan; Supartiningsih, Supartiningsih; Sitompul, Hestin Novalina
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3429

Abstract

Tuberculosis (TB) is an infectious disease with a very high prevalence in several countries in the world. Inadequate TB treatment can cause tuberculosis bacterial resistance to OAT (Anti-Tuberculosis Medicine). The emergence ofresistance M. tuberculosis can be in the form of single drug resistance (DR-TB) or a number or all of the first-line OAT (Multidrug Resistance Tuberculosis). The purpose of this study was to determine drug resistance factors which are influenced by patient habits, medical history, drugs, and health services. This type of research is qualitative research with a case study approach method. There were 6 informants in this study who were two MDR-TB patients, two patient personal monitors, a doctor, and the person in charge of the tuberculosis section. The results showed that the patient had a smoking habit and had a previous history of tuberculosis. In terms of treatment, patients do not routinely take medicines while in health services, the puskesmas have run them well so that there are no mistakes in management. The conclusion of this study is that smoking habits, previous history of tuberculosis disease, and not routine treatment are factors that greatly influence the occurrence of resistance
UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUNGA KECOMBRANG (Etlingera elatior) TERHADAP PERTUMBUHAN BAKTERI Salmonella thypi Nasution, Pandapotan; Marpaung, Jon Kenedy; Suharyanisa, Suharyanisa; Sitanggang, Rolastri
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3430

Abstract

Kecombrang (Etlingera elatior) is a type of spice that has long been known and used by humans as medicine. Kecombrang flower parts contain several chemical compounds, namely: alkaloids, flavonoids, and saponins. In addition, kecombrang flowers can also inhibit the growth of Salmonella typhi bacteria. This study aims to determine the concentration of ethanolic extract of kecombrang flower (Etlingera elatior) which is effective in inhibiting the growth of Salmonella typhi bacteria. The research sample was Kecombrang Flowers purchased at the Tarutung traditional market. This research was carried out experimentally including sampling, drying simplicia, maceration using 70% ethanol solvent, making extracts made using a rotary evaporator, and testing the antibacterial activity of kecombrang flowers using the disc diffusion method. Data analysis was conducted to see the effect of kecombrang flower ethanol extract on the activity of Salmonella typhi bacteria. The results of the study found that the results of phytochemical screening showed simplicia and ethanol extract of kecombrang flower leaves contained alkaloids, flavonoids, and saponins. While the results of the antibacterial activity test of the ethanolic extract of kecombrang flower leaves have antibacterial properties against Salmonella typhi at extract concentrations of 45%, 50%, 55%, and 60% with inhibition zone diameters of 9.4 mm, 12.2 mm, 14.8 mm, respectively. , 16.3mm. The most effective concentration of ethanol extract to inhibit the growth of Salmonella typhi was at a concentration of 60% with a larger inhibition zone diameter of 16.3 mm.
ANALISIS FAKTOR YANG MEMPENGARUHI PERTUMBUHAN KULTUR SEL CHO (Chinase Hamster Ovarium) PADA PEMBUATAN OBAT TRASTUZUMAB DI PT. BIO FARMA Silitonga, Maringan; Chandra, Devina; Fitri, Raissa; Nanda, Farahlina
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3431

Abstract

This study examines what factors can affect the growth of CHO cell cultures which are often used in biological and medical research and commercially in the production of therapeutic proteins. The purpose of this study was to determine whether CHO cells were able to grow and reproduce with the process flow and manufacturing method of drug preparations in accordance with the requirements of the applicable legislation. The workings of this research are divided into two stages, namely the microbiological stage and the biotechnology stage. The microbiological stage begins with making a working culture, then purification is carried out for culture rejuvenation, harvesting, cell culture breakdown, and purification of target cells. At the biotechnology stage, protein measurements were carried out, Optical Density 600 observations, polyacrylamide gel SDS electrophoresis, and gel electrophoresis staining.
STANDARISASI MANAJEMEN PENGELOLAAN OBAT DI INSTALASI FARMASI RUMAH SAKIT UMUM DAERAH Girsang, Vierto Irennius; Maharani, Maharani; Sinaga, Janno; Purba, Ivan Elisabeth
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3432

Abstract

Medicine management is a cycle in providing medicines which has four stages: selection, planning and procurement, distribution, and use. The objective of the research was to find out the standardization of medicinal managementin the IFRS of RSUD H. Sahudin, Kutacane, Aceh Tenggara regency. Quantitative and qualitative data were gathered from observation on documents and inteviews with IFRS personal. All stages of medicine management in the IFRS were measured by using an indicator of Depkes and WHO and compared with the result of the research. The results of the study showed that the drug management system according to the standard drug selection stage was in accordance with the standards set by the Ministry of Health of the Republic of Indonesia (2008). The planning stage has not met the standards set by WHO. The procurement stage has not met the standards set by the Indonesian Ministry of Health (2008). The distribution stage has not met the standards set by WHO (1993). The use stage has not met the standards set by WHO (1993). In order to increase the knowledge of officers about the calculation of drug management standards in hospitals.
FORMULASI DAN EVALUASI SEDIAAN LIP BALM DENGAN PEWARNA EKSTRAK UBI JALAR UNGU (Ipomoea batatas (L.) Lamk.) Supartiningsih, Supartiningsih; Sitorus, Elly Nurita; Silalahi, Yosy Cinthya Eriwaty; Khairunnisa, Khairunnisa
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2707

Abstract

Lip balm is a cosmetic preparation with the main components such as wax, fat, and oil from natural or synthesized extracts with the aim of preventing dryness of the lips by increasing lip moisture and protecting the adverse effects of the environment on the lips. The use of purple sweet potato as a dye is because purple sweet potato (Ipomoea batatas (L.) Lamk.) has an attractive color, the color of purple sweet potato is due to the presence of anthocyanin pigments which are derivatives of flavonoid compounds which are generally soluble in polar solvents. This study aims to formulate and evaluate lip balm preparations using purple sweet potato extract at concentrations of 3%, 6%, 9%, and without using purple sweet potato extract. This research is experimental research. Lip balm preparations were made by adding purple sweet potato extract with various concentrations (F1) 3%, (F2) 6%, (F3) 9%, and blank formula (F0) as the basis for lip balm preparations without purple sweet potato extract. Evaluation of the preparation includes homogeneity test, stability test, smear test, adhesion test, spreadability test, and pH test. The test results showed that purple sweet potato extract can be formulated in lip balm preparations that have a homogeneous composition, have good smearing power, good adhesion F0 (1 minute), F1 (1 minute 3 seconds), F2 (1 minute 8 seconds). seconds), F3 (1 minute 11 seconds), spreadability (5-5.7cm), pH test on all preparations showed a pH that was in accordance with the pH of the skin. And obtained formula 3 is the best formula.
PENETAPAN KADAR KALSIUM PADA BEDAK TABUR DARI BAHAN BAKU CANGKANG KERANG BULU (Anadaraantiquata) SECARA KOMPLEKSOMETRI Nurbaya, Siti; Sianipar, Artha Yuliana; Sitorus, Elly Nurita; Situmorang, Winton F.
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2708

Abstract

Until now, the utilization of clamshell waste has been limited to handicraft materials, whereas shellfish waste has a high calcium carbonate composition of about 98% which can be used as a source of calcium in the synthesis of compounds containing calcium metal. The purpose of this study was to determine the level of calcium contained in the shells of mussels and to determine the levels of calcium in the preparation of talcum powder which was added with powdered shells of feathers as an abrasive. Complexometric titration is also used to determine calcium levels in powder preparations formulated with feather shells powder. The results showed that the shells of feather shells contained calcium levels of 19.49% while the loose powder preparations contained calcium levels of 1.475%. The test results of the research on the formulation of loose powder preparations met the physical evaluation requirements. The pH test on loose powder, namely pH 7, meets the requirements of SNI 16-4399-1996, the pH value of cream cosmetic products is required to range from 4.5 to 8.0. The fine degree test is qualified because the loose powder can pass the sieving using a 100 mesh.
PENGGUNAAN EKSTRAK KULIT BUAH NAGA MERAH (Hylocereuscostaricensis (F.A.C. Weber) Britton & Rose.) DALAM FORMULASI PEWARNA RAMBUT Masyithah, Cut; Maimunah, Siti; Zuhairiah, Zuhairiah; Sitorus, Cahaya Amalia
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v4i2.2711

Abstract

Hair is a symbol of beauty in humans which is one of the adnexa (parts) of the skin that grows from the skin. Hair grows from the root, hair that is in the dermis layer, and through the hair follicle channel out of the skin. There are some differences in each hair such as type, shape, amount, and color. Dragon fruit peel is an agricultural waste that contains high anthocyanin natural dyes. Anthocyanin is a dye that plays a role in giving red color which has the potential to be a natural colorant for food and can be used as an alternative to synthetic dyes that are safer for health. Anthocyanin was taken by the extraction method. The results showed that the higher the concentration of the adjuvant used, the darker the gray hair. The use of auxiliary materials in a concentration of 0.5% produces a brownish-black color, and a concentration of 1% produces a dark black color. The preparation of gray hair dye made with the formula of 2.5% dragon fruit peel extract and 1% adjuvant produces a deep black color, so pyrogallol, copper (II) sulfate, xanthan gum with a concentration of 0.5% are used in order to distinguish changes on white hair (grey), due to the EKBN formula or from added additives.

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