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International Journal of Health Science and Technology
Published by Universitas Aisyiyah Yogyakarta
ISSN : -     EISSN : 26858673     DOI : https://doi.org/10.31101/ijhst
Core Subject : Humanities, Health, Engineering,
Humanities Engineering Health Professions Nursing Public Health
International Journal of Health Science and Technology published since July 2019 with ISSN Online: 2685-8673 by LPPM Universitas Aisyiyah Yogyakarta. IJHST Published third a year in January, July and November. This journal contains research papers as results of research which have already been reviewed by reviewers in the field of health, science and technology. Every article that goes to the editorial staff will be selected through Initial Review processes by Editorial Board. Then, the articles will be sent to peer reviewers and will go to the next selection by Blind Review Process. After that, the articles will be returned to the authors to revise. These processes take a month for a maximum time. For each manuscript, peer reviewers will rate the substantial and technical aspects, peer reviewers who collaborate with International Journal of Health Science and Technology. 1. Health 2. Science 3. Technology
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 254 Documents
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In Silico Study of Brazilin from Secang Wood (Caesalpinia Sappan L) as a Candidate for Splenomegaly Therapy Youngest, Racy; Rusdianto, Rusdianto; Kamisah, Yusof; Maskoen, Ani Melani; Safitri, Ratu
International Journal of Health Science and Technology Vol. 6 No. 3 (2025): April
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v6i3.4032

Abstract

Brazilin is a flavonoid found in secang (sappan) wood extract (Caesalpinia sappan L) currently undergoing clinical trials in phase 2 for the treatment of thalassemia patients. It is recognized for its antioxidant effects and its efficacy as a strong iron chelator, facilitating the binding and excretion of excess iron in the bloodstream of patients with thalassemia. This flavonoid compound may serve as a Janus kinase 2 (JAK2) inhibitor through the EPO/EPOR/JAK2/STAT5 pathway, which is responsible for splenomegaly (enlarged spleen). This study aims to investigate the mechanism by which sappan wood metabolite chemicals (brazilin) inhibit JAK2 in silico. This inhibition is expected to reduce splenomegaly in thalassemia patients and serve as an alternative to ruxolitinib (conventional medications). The pharmacokinetic profile of the ligand is predicted according to Lipinski's rule, while the binding energy (ΔG), initiation constant, and chemical bonds are examined using molecular docking with AutoDock v.4.25. This study successfully determined that brazilin, with a binding energy of -8.37 kcal/mol, is comparable to ruxolitinib, which has a binding energy of -8.71 kcal/mol. This finding shows that brazilin derived from sappan wood contains bioactive chemicals with potential JAK2 inhibitory activities. This finding establishes a foundation for further research aimed at developing new therapeutic agents for the treatment of splenomegaly in β-thalassemia and associated disorders.
How HIV/AIDS health education boosts high school students’ knowledge Anggraini, Lutfi; Rokhanawati, Dewi
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.3775

Abstract

The incidence of HIV/AIDS continues to rise. The high number of cases among adolescents is due to their lack of knowledge and attitudes about HIV/AIDS, which directly affects the prevention of this disease. Knowledge about HIV/AIDS is considered crucial, as it plays a role in shaping public perceptions, thereby influencing their understanding and awareness. HIV/AIDS health education for adolescents can be an effective approach to developing their knowledge about reproductive health and sexually transmitted diseases. This study aims to investigate the impact of HIV/AIDS health education on the knowledge level of 11th-grade students at SMA Negeri 1 Pundong. This study employed nonequivalent pretest-posttest control group design. The sampling technique used was probability sampling, with a total of 32 respondents divided into an experimental group of 16 and a control group of 16. Data were analyzed using non-parametric tests: the Wilcoxon matched-pairs test and the Mann-Whitney U test. Based on the pretest and posttest results, the average knowledge score in the experimental group increased from 60.69 to 83.00, while in the control group it rose from 63.70 to 73.00. The analysis showed a significant difference in knowledge levels before and after the HIV/AIDS health education intervention in both the experimental and control groups, with a p-value of 0.004 (p < 0.05). This study concludes that HIV/AIDS health education has a significant effect on improving the knowledge of 11th-grade students at SMA Negeri 1 Pundong.
The relationship between social support and religiosity on psychological well-being in final year students Rezeky, Mayang Tri; Ariyanto, Mustaqim Setyo; Khoiryasdien, Andhita Dyorita
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.3949

Abstract

A person is considered as a university student when they enter a college or university. The hardest phase of being a university student is when they enter their final semester because they start working on their final assignments. As final year students in college, they certainly have pressure. The purpose of this study is to determine the effect of social support and religious beliefs of final year students on their psychological well-being. This study employed a quantitative approach with an emphasis on correlation through the distribution of questionnaires. The sample population of this study consisted of final year students, who were usually between 20 and 24 years old. A total of 120 participants were selected for the survey through the nonprobability sampling method. When analyzing the data, the assumption test was used. In this study, the variables of social support, religiosity, and psychological well-being were tested for their hypotheses. The results of the study showed a significance level of 0.000 <0.05. The r square value of psychological well-being gave an effective contribution of 61.55%, and the r square value of psychological well-being gave an effective contribution of 9.55% when combined with social support indicated a strong relationship, which means that there is a relationship between social support and psychological well-being in final year students, but there is no relationship between religiosity and psychological well-being in final year students.
The correlation between hyperuricemia and the risk of congestive heart failure: a cross-sectional study in Indonesia Nadia, Farah; Julyani, Sri; Namirah, Hanna Aulia; Kartika, Irna Diyana; Nurhikmawati, Nurhikmawati
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.3959

Abstract

Congestive Heart Failure (CHF) is a leading cause of morbidity and mortality worldwide and is the second most common cause of death in Indonesia. One factor that has recently gained attention is hyperuricemia, a condition characterized by elevated serum uric acid levels, which is closely linked to the pathogenesis of cardiovascular diseases. The underlying mechanism involves increased activity of the enzyme xanthine oxidase, which triggers oxidative stress, endothelial dysfunction, and systemic inflammation, all of which contribute to the progression of CHF. This study aims to examine the relationship between serum uric acid levels and the incidence of CHF at RSUD (Regional General Hospital) I Lagaligo, East Luwu Regency. This study employed observational analytic approach with cross-sectional design. Data were collected from the medical records of 102 CHF patients treated between January 2023 and June 2024. Uric acid levels and CHF types were classified based on ejection fraction (EF). Data analysis was done using the Chi-Square test. The results showed a significant association between uric acid levels and the type of CHF (p < 0.001). Among patients with reduced ejection fraction, 83.7% had elevated uric acid levels, while 55% of patients with preserved ejection fraction had normal levels. Conclusion: There is a significant correlation between uric acid levels and CHF. Monitoring uric acid levels has the potential to serve as a clinical indicator in the evaluation and management of CHF patients.
Factors associated with lost to follow-up behavior among HIV/AIDS patients undergoing ARV therapy Ricki, Ricki Hendri Yudiawan; Nova, Nova Mega Rukmana; Nana, Nana Novariana
International Journal of Health Science and Technology Vol. 6 No. 3 (2025): April
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.4012

Abstract

At Puskesmas (Primary Health Center) Madukoro, in May 2024, it was found that out of 46 patients undergoing antiretroviral (ARV) therapy, 10 had a history of lost to follow-up behavior, either temporarily or permanently. This represents 21.7% of patients lost to follow-up, based on the total number of patients who had ever received ARV treatment. This figure exceeds the World Health Organization (WHO) standard, which states that no more than 20% of patients should be lost to follow-up within one year. This study aims to identify the factors influencing lost to follow-up behavior among HIV/AIDS patients undergoing ARV therapy at Madukoro Public Health Center, North Lampung Regency. A descriptive-analytic design was used, employing a quantitative research method with a cross-sectional approach. The study population consisted of all 46 HIV/AIDS patients at the health center receiving ARV treatment, with total sampling applied. The findings revealed a significant relationship between perceived vulnerability and lost to follow-up behavior (p = 0.000), perceived severity and lost to follow-up behavior (p = 0.000), and perceived barriers and lost to follow-up behavior (p = 0.001). However, there was no significant relationship between perceived benefits and lost to follow-up behavior (p = 0.169). There was also a significant relationship between self-efficacy and lost to follow-up behavior (p = 0.001), as well as between environmental support and lost to follow-up behavior (p = 0.000). It is recommended that the Head of Madukoro Public Health Center disseminate the results of this study to the staff responsible for the HIV P2 Program, healthcare workers, and other employees in order to develop appropriate strategies or work programs to prevent lost to follow-up cases among HIV/AIDS patients.
Safety analysis of X-ray radiation exposure in installation Iqna, Iqna Purwitasari; Nugroho, Anshor; Utami, Asih Puji
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.4035

Abstract

Radiology is important in early detection and risk assessment through real-time imaging. However, radiation safety in radiology installations remains a major concern in protecting patients, medical personnel, and the public from ionizing radiation exposure to avoid exceeding the Dose Limit Value (NBD). This study aims to analyse the results of X-ray radiation exposure and evaluate the radiation safety procedures implemented to reduce the risk of radiation exposure in the Radiology Installation of Panti Nugroho Sleman Hospital. The method used in this research is qualitative with an experimental approach conducted at Radiology Installation of Panti Nugroho Hospital Sleman in August 2024 - January 2025. Data collection was carried out at 10 measurement points where each point was measured three times then the measurement results were calculated using the formula and then compared with BAPETEN Regulation No. 5 of 2016. The results obtained are the value of radiation exposure measurements for 10 points of measurement area on conventional aircraft, namely 0 µSv / hour, 0 µSv / hour, 0.03 µSv / hour, 0 µSv / hour, 0.33 µSv / hour, 0.03 µSv / hour, 0 µSv / hour, 0.13 µSv / hour, 0.03 µSv / hour, and 0 µSv / hour. As well as radiation exposure measurement values for 10 points of measurement area in the panoramic plane, namely 0 µSv/hour, 0 µSv/hour, 0 µSv/hour, 0 µSv/hour, 0.03 µSv/hour, 0 µSv/hour, 0 µSv/hour, 0 µSv/hour, 0 µSv/hour, 0 µSv/hour. In addition, standard operating procedures such as room management, equipment maintenance, provision of aprons, implementation of radiation exposure testing, use of TLD (Thermoluminescence Dosimeter), and health checks have been implemented in a structured manner in order to prevent and protect the safety of all parties and the environment. It is expected that this research can be useful for health aspects for radiation workers such as being able to identify ways to reduce radiation exposure in order to avoid stochastic effects, gene mutations, and so on by developing more effective safety protocols to reduce X-ray radiation exposure for radiology workers and the public.
Image quality comparison of abdominal MSCT: Injector vs. Syringe Method Faesol, Ahmad; Permana, Hendry Dwi Widya; Hidayat, Fathur Rachman
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.4209

Abstract

Afriani, D. (2024). Buku Ajar Epidemiologi Penyakit Tidak Menular. Penerbit NEM. Choi, M., Lee, Y., & Jung, S. (2022). The Image Quality and Diagnostic Performance of CT with Low-Concentration Iodine Contrast (240 mg Iodine/mL) for the Abdominal Organs. Diagnostics, 12(3), 752. https://doi.org/10.3390/diagnostics12030752  Endrikat, J., Barbati, R., Scarpa, M., Jost, G., & Ned Uber, A. E. (2018). Accuracy and Repeatability of Automated Injector Versus Manual Administration of an MRI Contrast Agent-Results of a Laboratory Study. Investigative Radiology, 53(1), 1—5. https://doi.org/10.1097/rli.0000000000000403  Flynn, W., & Vickerton, P. (2025). Anatomy, Abdomen and Pelvis: Abdominal Wall. Francis, I. R., Cohan, R. H., McNulty, N. J., Platt, J. F., Korobkin, M., Gebremariam, A., & Ragupathi, K. I. (2003). Multidetector CT of the liver and hepatic neoplasms: effect of multiphasic imaging on tumor conspicuity and vascular enhancement. AJR. American Journal of Roentgenology, 180(5), 1217–1224. https://doi.org/10.2214/ajr.180.5.1801217  Irfan Irfan, & Rahmat Widodo. (2024). Tatalaksana Pemeriksaan CT Scan Abdomen Dengan Kontras Dengan Klinis CA Recti. DIAGNOSA: Jurnal Ilmu Kesehatan Dan Keperawatan, 2(1), 113–123. https://doi.org/10.59581/diagnosa-widyakarya.v2i1.2711  Koshi, R. (2025). 153The abdominal cavity. In R. Koshi & R. Koshi (Eds.), Cunningham’s Manual of Practical Anatomy Volume 2 Thorax and Abdomen (p. 0). Oxford University Press. https://doi.org/10.1093/med/9780198939016.003.0013  Li, S., Yuan, X., Yi, Z., Dai, H., Yang, L., Dai, Z., & Yan, G. (2023). Dual-phase contrast-enhanced multislice computed tomography scans play a key role in the diagnosis of abdominal wall desmoid-type fibromatoses. Technology and Health Care : Official Journal of the European Society for Engineering and Medicine, 31(S1), 45–54. https://doi.org/10.3233/THC-236005  Li, X.-M., Reng, J., Zhou, P., Cao, Y., Cheng, Z.-Z., Xiao, Y., & Xu, G.-H. (2014). Solitary fibrous tumors in abdomen and pelvis: imaging characteristics and radiologic-pathologic correlation. World Journal of Gastroenterology, 20(17), 5066–5073. https://doi.org/10.3748/wjg.v20.i17.5066  McDermott, M., Kemper, C., Barone, W., Jost, G., & Endrikat, J. (2020). Impact of CT Injector Technology and Contrast Media Viscosity on Vascular Enhancement: Evaluation in a Circulation Phantom. The British Journal of Radiology, 93(1109), 20190868. https://doi.org/10.1259/bjr.20190868  Melikian, R., Goldberg, S., Strife, B. J., & Halvorsen, R. A. (2016). Comparison of MDCT protocols in trauma patients with suspected splenic injury: superior results with protocol that includes arterial and portal venous phase imaging. Diagnostic and Interventional Radiology (Ankara, Turkey), 22(5), 395–399. https://doi.org/10.5152/dir.2016.15232  Paparo, F., Garello, I., Bacigalupo, L., Marziano, A., Galletto Pregliasco, A., Rollandi, L., Puppo, C., Mattioli, F., Puntoni, M., & Rollandi, G. A. (2014). CT of the abdomen: degree and quality of enhancement obtained with two concentrations of the same iodinated contrast medium with fixed iodine delivery rate and total iodine load. European Journal of Radiology, 83(11), 1995–2000. https://doi.org/10.1016/j.ejrad.2014.07.010  Seeram, E. (2016). Computed Tomography: Physical Principles, Clinical Applications, and Quality Control (F. Edition (ed.)). Trigui, M., Ouanes, Y., Rahoui, M., Chaker, K., Marrak, M., & Nouira, Y. (2023). Massive hydronephrosis due to obstruction by upper urinary tract urothelial carcinoma with compression of the inferior vena cava. Urology Case Reports, 50, 102539. https://doi.org/10.1016/j.eucr.2023.102539  Wijokongko, A., Pudyastuti, S., & Widiyanto, A. (2017). Pengaruh fase pemeriksaan MSCT multiphase terhadap gambaran lesi hepar. Jurnal Teknologi Kesehatan, 7(2), 101–108.
Analysis management and referral process for victims of violence in house ladder in first level health services Rosida, Luluk; Putri, Intan Mutiara
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.4247

Abstract

The health impacts experienced by victims of domestic violence, especially women, are quite widely reported. From the results of research obtained in the United States, as many as 37% of women who experienced violence from perpetrators and underwent examinations at health services ended up in hospitalisation in emergency services. The purpose of this study is to analyse the Management and Referral Process of Victims of Domestic Violence (Case Study at first-level health services). The research method employed is descriptive research, specifically analysing primary data to describe the violence that existed over 3 years. The research location was at one of the first-level health services (community health centres) in Bantul Regency. The results showed that the characteristics of victims of domestic violence based on gender were mostly experienced by women, as many as 15 people (78.9%), and men, as many as 4 people (21.1%). Based on interviews with officers, the management provided ranged from first aid for injuries to counselling by community health centre officers or a referral process for serious injuries. However, most victims did not want to continue reporting to the authorities or the legal realm. And most victims reported that they would resolve the matter internally within their respective families. The findings of this research contribute to describing the management and referral process for victims of domestic violence to primary health care.
The influence of self-control training on self-regulated learning in Merdeka Belajar Kampus Merdeka (MBKM) collage students Malahati, Fildzah; Rohmadani, Zahro Varisna; Winarsih, Tri
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.4271

Abstract

This study aims to examine the effectiveness of self-control training on self-regulated learning in UNISA collage students involved in the MBKM program. This research employs a quantitative method with an experimental design, specifically a pre-test post-test control group design. The criteria for subjects in this study are: 1) UNISA students in Yogyakarta participating in the MBKM program in 2024; and 2) willingness to complete the entire training process. The sample of the study was taken using a purposive sampling technique. The number of participants was 14 students who were participating in MBKM, consisting of 12 females and 2 males aged between 20 and 23 years old. Data collection involves using quesionare of the Self-Regulated Learning (SRL) likert scale, observations, and training evaluations conducted according to the Self-Control Training module. Data analysis methods include paired sample t-test to examine differences between pre-test and post-test conditions within a single group and independent sample t-test to assess differences between two groups (experimental and control). Based on the research results, a 2-tailed significance value of 0.013 < 0.05 indicates a significantly positive effect of the intervention. Based on the research findings, a two-tailed significance value of 0.013 was obtained, which is less than 0.05, indicating a significant positive effect of the intervention. Consequently, the Self-Control Training has a positive impact on the enhancement of Self-regulated Learning among MBKM students. The data analysis process was conducted using SPSS version 23 for Windows.
Impact of intergenerational community health intervention on adolescents’ views of older adults in Yogyakarta Rohmawati, Zubaida; Indriani, Indriani; Linawati, Sri Lestari; Fatmawati, Veni; Kyswantoro, Yunita Firdha
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): Juli
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.4281

Abstract

Low adolescent participation hinders the effectiveness of the Youth Integrated Health Post (Posyandu Remaja). This study evaluates the impact of the NGAJENI Program—an intergenerational intervention based on health education, physical activity, and collaborative arts—on adolescents' perceptions of the elderly and the significance and magnitude of these changes. A cluster quasi-experimental design was implemented in two kelurahan of Mergangsan Sub District, Yogyakarta. Thirty-seven adolescents aged 15–24 years were purposively sampled and allocated by cluster to the intervention group (n = 20) or control group (n = 17). The intervention spanned 3 month and comprised six 90-minute sessions. Perception was measured via a validated 12-item Likert scale (score range 12–60; Cronbach’s α = 0.89) at pre- and post-intervention. Within-group changes were examined using paired t-tests, between-group differences in change scores (Δ) with independent t-tests, and effect sizes calculated by Cohen’s d. Baseline demographics were comparable (all p > 0.05). The intervention group’s mean perception score increased from 40.20 ± 4.15 to 47.10 ± 3.80 (Δ = 6.90; paired t = –8.32; p < 0.001; d = 1.73), while the control group’s score rose from 39.85 ± 4.30 to 42.35 ± 4.05 (Δ = 2.50; paired t = –3.12; p = 0.006; d = 0.60). Independent t-test confirmed significantly greater perceptual change in the intervention cohort (t = 3.97; p < 0.001). The NGAJENI program significantly improves adolescents' perceptions of the elderly and strengthens intergenerational solidarity at the Youth Posyandu.

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