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Salman
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Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123
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INDONESIA
Journal of Pharmaceutical and Sciences.
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Articles 712 Documents
Penetapan Kadar Tanin Daun Mangkokan (Polyscias scutellaria (Burm.f.) fosberg) Dan Daun Jambu Biji (Psidium guajava L.) Secara Spektrofotometri UV-Visible Putri Yupa Hasibuan; Anny Sartika Daulay; Ridwanto Ridwanto; Ainil Fithri Pulungan
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.972

Abstract

Tannins are secondary metabolites belonging to the polyphenol group that exhibit important biological activities, including antioxidant, antibacterial, and anti-inflammatory effects. Mangkokan leaves (Polyscias scutellaria) and guava leaves (Psidium guajava) have long been traditionally used; however, quantitative data regarding their tannin content, particularly in relation to different extraction methods, remain limited. This study aimed to determine total tannin content and identify tannin types in 70% ethanol extracts and infusions of both plants using UV-Vis spectrophotometry. The methodology included phytochemical screening, identification of hydrolyzable and condensed tannins using specific reagents, and quantitative determination of total tannin content using the Folin–Ciocalteu method with gallic acid as a standard. Measurements were carried out at a maximum wavelength of 769 nm, with a regression equation of y = 0.2186x + 0.0024 and a coefficient of determination (R²) of 0.994. The results showed that all samples contained both hydrolyzable and condensed tannins. The highest tannin content was found in the ethanol extract of guava leaves (17.7998 ± 0.0789 mg/g), while the lowest was observed in the infusion of mangkokan leaves (14.0788 ± 0.1986 mg/g). These findings indicate that the type of solvent and extraction method significantly affect tannin yield, with 70% ethanol being more effective than water. In conclusion, both mangkokan and guava leaves have potential as natural sources of tannins, with ethanol extraction providing more optimal results. UV-Vis spectrophotometry proved to be an accurate, sensitive, and reliable method for the quantitative analysis of tannins in plant materials.
Formulasi, Evaluasi Dan Penentuan Nilai SPF Sediaan Body Lotion Ekstrak Etanol Kopi Arabika Jenis Longberry Fanny Anggreany Santosa; Rafita Yuniarti; Minda Sari Lubis; Zulmai Rani
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1503

Abstract

Background: Exposure to ultraviolet (UV) radiation can cause skin damage such as erythema, premature aging, and skin cancer. Although sunscreens are widely used, synthetic UV filters may cause side effects. Therefore, alternative natural ingredients with antioxidant activity are needed, such as Arabica coffee beans (Coffea arabica), which are rich in polyphenols, particularly chlorogenic acid, as potential sunscreen agents. Objective: This study aims to formulate a body lotion containing ethanol extract of longberry-type Arabica coffee beans, evaluate its physical properties, and determine its Sun Protection Factor (SPF) value in vitro. Methods: This experimental study included phytochemical screening, extraction using 96% ethanol, and SPF determination using a UV-Vis spectrophotometer with the Mansur method. The body lotion was formulated with varying extract concentrations of 0–3% and evaluated for organoleptic properties, homogeneity, pH, viscosity, spreadability, adhesiveness, emulsion type, stability, and irritation test. Results: The extract contained alkaloids, flavonoids, tannins, saponins, steroids, and glycosides. The highest SPF value of the extract was 36.727 at a concentration of 1000 ppm (ultra protection category). The best formulation was found at a 3% concentration with an SPF value of 10.554 (maximum protection category). All formulations met physical quality requirements and showed no irritation. Conclusion: The ethanol extract of longberry-type Arabica coffee beans has potential as a natural sunscreen active ingredient. Increasing the extract concentration is directly proportional to the increase in SPF value, with the 3% formulation showing the best performance.