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JIKA
Published by Universitas Abdurrab
ISSN : 2987873X     EISSN : 29880009     DOI : https://doi.org/10.36341/jika
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health
JIKA (Jurnal Ilmu Kesehatan Abdurrab) has been published since March 2023 by the Abdurrab University Research and Community Service Institute in Pekanbaru. It is released four times a year: in March, June, September, and December. This journal focuses on the fields of nursing, midwifery, medicine, pharmacy, physiotherapy, health analysis, and public health. The aim of JIKA is to provide a platform for authors to publish their research findings that are beneficial to the community. The journal offers opportunities for researchers and practitioners in various health disciplines to share knowledge, ideas, and the latest findings in those fields. With its regular publication, JIKA is committed to being a sustainable and influential source of information in the academic and healthcare practice domains. Articles published in JIKA (Jurnal Ilmu Kesehatan Abdurrab) cover various topics relevant to the health field. Authors are invited to contribute research articles, literature reviews, case studies, and other scientific contributions related to nursing, midwifery, medicine, pharmacy, physiotherapy, health analysis, and public health. By publishing high-quality articles, JIKA aims to promote the development and understanding of health sciences. The journal also plays a role in disseminating up-to-date information, facilitating dialogue among researchers, practitioners, and academics, and making meaningful contributions to the improvement of healthcare quality. Thus, JIKA (Jurnal Ilmu Kesehatan Abdurrab) serves as an important platform for the development of health sciences, promoting collaboration among researchers and encouraging the application of beneficial knowledge for the advancement of health and well-being in society.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 151 Documents
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Analysis Of Lead (Pb), Zing (Zn), and Copper (Cu) Levels in Catfish (Pangasius hypophthalmus) From Kampar Regency Using Atomic Absorption Spectrophotometry Subardi Bali; Vonny Kurnia Utama; Sri Kartini; Dwi Hestia Anjani
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 2 (2026): Volume 4 Nomor 2 Juni 2026
Publisher : LPPM Universitas Abdurrab

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Abstract

Heavy metal contamination in aquatic environments has become a serious issue due to its potential adverse effects on human health through the food chain. This study aims to determine the concentrations of lead (Pb), zinc (Zn), and copper (Cu) in catfish (Pangasius hypopthalmus) collected from three different locations: floating cages under the Rantau Berangin Bridge, the Danau Bingkuang Bridge, and a cultivation pond in Silam Village. The samples were analyzed using Atomic Absorption Spectrophotometry (AAS) after digestion with a microwave digester. The results showed Pb concentrations in samples JRB 1, JRB 2, JDB 1, JDB 2, KDS 1, and KDS 2 were 479 mg/kg; 16.27 mg/kg; 165.68 mg/kg; 356.21 mg/kg; 99.6 mg/kg; and 336.57 mg/kg, respectively. Zn concentrations were 8.05 mg/kg; 0 mg/kg; 2.45 mg/kg; 1.09 mg/kg; 24.3 mg/kg; and 0.490 mg/kg, while Cu concentrations were 2.84 mg/kg; 2.81 mg/kg; 1.76 mg/kg; 0 mg/kg; 15.65 mg/kg; and 0 mg/kg, respectively. All Pb levels exceeded the maximum limit set by SNI 2729:2021, which is 0.3 mg/kg. Meanwhile, Zn and Cu levels remained within safe limits based on the decree of the Director General of BPOM No. 03725/B/SK/VII/89. Based on these findings, it can be concluded that heavy metal contamination, particularly by Pb, was present in the tested samples, rendering them unsuitable for consumption without further monitoring and testing
the THE RELATIONSHIP BETWEEN REPRODUCTIVE HEALTH EDUCATION AND CHANGES IN ADOLESCENTS KNOWLEDGE IN PREVENTING UNWANTED PREGNANCY AT SMP NEGERI 13 PEKANBARU: REPRODUCTIVE HEALTH EDUCATION Brilian Dini Ma. Iballa; Bdn. Ade Febriani, SST., M. Kes Ade
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 2 (2026): Volume 4 Nomor 2 Juni 2026
Publisher : LPPM Universitas Abdurrab

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Background: Unwanted pregnancy is a pregnancy that is not desired by the woman or her surroundings. This occurs due to various factors, making its presence unwanted by one or both prospective parents. Health education is an effort to create behaviors that support health. Objective: To determine the relationship between reproductive health education and changes in adolescents knowledge in preventing unwanted pregnancy at SMP Negeri 13 Pekanbaru. Methods: Quantitative research with a one group pretest-posttest design. The sample consisted of 70 respondents using a total sampling technique. Data were collected using questionnaires before and after education. Data were analyzed using the Wilcoxon test and Spearman correlation. Results: Before education, knowledge was good in 2 respondents (2.9%), fairly good in 14 respondents (20%), and poor in 54 respondents (77.1%). After education, knowledge was good in 57 respondents (81.4%), fairly good in 11 respondents (15.7%), and poor in 2 respondents (2.9%). The Wilcoxon test showed a p-value = 0.001 < 0.005, and the Spearman correlation test showed a p-value = 0.001 < 0.005, indicating changes in knowledge and a significant relationship. Conclusion: Reproductive health education increases adolescents’ knowledge in preventing unwanted pregnancy.
Antihypertensive Therapy, Blood Pressure Variability, and Dementia Risk in Asian Populations: A Systematic Review and Meta-Analysis sepridawati siregar; Nora Idiawati; Larysa Fernenda; Yessi Rahayu; Muchsin Maulana
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 2 (2026): Volume 4 Nomor 2 Juni 2026
Publisher : LPPM Universitas Abdurrab

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Abstract

Hypertension and blood pressure variability (BPV) are recognized as modifiable risk factors for dementia, yet evidence in Asian populations remains limited. This study systematically evaluated the association between antihypertensive therapy, BPV, and dementia risk in Asia. A systematic search of ScienceDirect, PubMed, and MEDLINE (2010–2024) was conducted following PRISMA guidelines. Studies reporting hazard ratios (HRs) for dementia outcomes in Asian populations were included. Of 1,246 identified records, 22 studies met criteria for qualitative synthesis and 15 were included in the meta-analysis (11 cohort, 4 case-control). Antihypertensive therapy was associated with reduced dementia risk (pooled HR ≈ 0.84), while high BPV was linked to increased risk (pooled HR ≈ 1.23). Meta-regression identified study design and mean age as sources of heterogeneity. Overall, antihypertensive therapy appears protective, whereas elevated BPV increases dementia risk in Asian populations, emphasizing the importance of both blood pressure control and stability in preventing cognitive decline.
The Relationship Between Knowledge Level and Medication Adherence Among Pulmonary Tuberculosis Patients at Arifin Achmad Regional General Hospital, Pekanbaru Wahyu Margi Sidoretno; Hera Dameira; Sri Kartini
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 2 (2026): Volume 4 Nomor 2 Juni 2026
Publisher : LPPM Universitas Abdurrab

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Abstract

Pulmonary tuberculosis remains one of the major public health problems in Indonesia, as it requires long-term treatment and optimal patient adherence. Patients’ knowledge regarding the disease, therapeutic regimen, treatment duration, and consequences of non-adherence plays an important role in supporting successful tuberculosis therapy. This study aimed to analyse the association between knowledge level and medication adherence among patients with pulmonary tuberculosis at Arifin Achmad Regional General Hospital, Pekanbaru. This study employed an observational analytic design with a cross-sectional approach. A total of 68 respondents were recruited using a total sampling technique. Data were collected using questionnaires designed to assess patients’ knowledge level and medication adherence. Data analysis was performed using the Spearman Rank correlation test. The results showed a significant positive association between knowledge level and medication adherence among patients with pulmonary tuberculosis, with a p-value of <0.001 and a correlation coefficient of r=0.542. This correlation coefficient indicates a moderate positive relationship, meaning that patients with a higher level of knowledge tend to have better adherence to tuberculosis treatment. This study concludes that knowledge level is significantly associated with medication adherence among patients with pulmonary tuberculosis. Strengthening patient education, medication counseling, and continuous health promotion should be optimized to improve the success of tuberculosis therapy.
Antioxidant Activity of Palm Kernel Oil-Vitamin C Nanoemulsion Evaluated Using the DPPH Assay Method Muslim Suardi; Yunita Amanda; Yan Hendrika
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 2 (2026): Volume 4 Nomor 2 Juni 2026
Publisher : LPPM Universitas Abdurrab

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Abstract

Palm kernel oil (PKO) is an oil obtained from palm seeds (Elaeis guineensis Jacq) contains natural antioxidants. Objectives: Purposes of the study were to formulate, determine the physical characteristics of PKO nanoemulsions, and evaluate antioxidant activity. Method: The nanoemulsion was prepared into five formulations, F1, F2, F3, and F4 contained PKO at concentrations of 2, 2.5, 3, and 3.5% of PKO, respectively. F1, F2, F3, and F4 were added with vitamin C at a concentration of 2,5%. F5 as a control contained 3.5% PKO without vitamin C. Physical evaluations included organoleptic, viscosity, pH, centrifugation, transmittance, droplet size, zeta potential, and freeze-thaw tests. Antioxidant activity was evaluated using the DPPH assay method. Results: All of the physical evaluations fulfilled the requirement of nanoemulsion formulation. Antioxidant activity (IC50 value) of F1, F2, F3, F4, and F5 was 2.98 ± 0.21; 2.25 ± 0.23; 1.29 ± 0.05; 1.17 ± 0.12; and 51.96 ± 37.19 ppm, respectively. It was indicated very strong antioxidant activity, while for F5 (PKO without vitamin C) has strong activity (IC50 of 51.9 ppm). Conclusions: It is concluded that the PKO can be used as a antioxidant. PKO-Vitamin C can be formulated as a stable nanoemulsion.
Formulasi dan Evaluasi Fisik Patch Transdermal Ekstrak Daun Jambu Biji (Psidium guajava L.) Muhammad Faruqi Perdana; Vonny Kurnia Utama; Lovera Anggraini; Vilda Tri Anisa
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 1 (2026): Volume 4 Nomor 1 Maret 2026
Publisher : LPPM Universitas Abdurrab

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Abstract

Daun jambu biji (Psidium guajava L.) mengandung banyak senyawa bioaktif, termasuk flavonoid, tanin, saponin, dan lain-lain, yang dapat digunakan untuk membuat patch transdermal berbasis polimer. Penelitian ini dilakukan secara eksperimental dan bertujuan untuk memformulasikan dan mengevaluasi karakteristik fisik patch transdermal ekstrak daun jambu biji dengan variasi polimer HPMC dan PVP. Metode maserasi digunakan untuk mengekstraksi daun jambu biji dengan etanol 96%. Kemudian, tiga formula dibuat: F1 dengan HPMC 0,6%, F2 dengan HPMC:PVP 3:1, dan F3 dengan HPMC:PVP 1:3. Organoleptis, ketebalan, pH, ketahanan lipatan, keseragaman bobot, susut pengeringan, dan daya serap kelembapan adalah faktor-faktor yang dievaluasi. Data dievaluasi dengan One Way ANOVA. Nilai pH F1 adalah 5,55 +/- 0,30; 5,54 +/- 0,02; dan 5,66 +/- 0,14, masing-masing. Ketahanan lipatan F1 tertinggi adalah 480,66 +/- 6,02, dan susut pengeringan terendah adalah 8,67%. Patch berbentuk persegi dan berwarna coklat dengan bau khas. Meskipun variasi polimer tidak memengaruhi pH atau daya serap kelembapan, variasi polimer sangat memengaruhi ketahanan lipatan, keseragaman bobot, dan susut pengeringan. Berdasarkan fleksibilitas dan stabilitas fisik, F1 adalah formula yang paling cocok.
Formulasi Gel Ekstrak Bonggol Nanas dan Aktivitas Antibakteri terhadap Staphylococcus aureus Muhammad Faruqi Perdana; Vonny Kurnia Utama; Kony Putriani; Ahridansyah
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 2 (2026): Volume 4 Nomor 2 Juni 2026
Publisher : LPPM Universitas Abdurrab

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Bonggol nanas (Ananas comosus (L.) Merr.) mengandung bromelain dan metabolit lain yang berpotensi sebagai antibakteri. Penelitian ini bertujuan memformulasikan ekstrak bonggol nanas ke dalam sediaan topikal berbasis nanogel serta mengevaluasi karakteristik fisik dan aktivitas antibakterinya terhadap Staphylococcus aureus. Penelitian menggunakan desain eksperimental laboratorium. Bonggol nanas diekstraksi dengan metode maserasi menggunakan etanol 96%, kemudian diformulasikan menjadi empat sediaan, yaitu F0 tanpa ekstrak, FI ekstrak 1,5%, FII ekstrak 3%, dan FIII ekstrak 5%. Evaluasi meliputi organoleptis, homogenitas, pH, viskositas, pengukuran ukuran partikel, stabilitas selama 28 hari, dan aktivitas antibakteri menggunakan metode difusi sumuran. Seluruh formula berbentuk semi padat, homogen, dengan pH awal F0, FI, FII, dan FIII berturut-turut 5,50; 5,42; 5,33; dan 5,38. Viskositas awal berada pada rentang 16.356-31.917 cPs dan masih sesuai rentang viskositas gel. Pengukuran ukuran partikel belum dapat mengonfirmasi pembentukan nanogel karena sistem terlalu viskos, sehingga sediaan dikategorikan sebagai gel. Formula FII menghasilkan zona hambat tertinggi sebesar 9,00 mm dengan kategori sedang. Ekstrak bonggol nanas berpotensi sebagai bahan antibakteri alami dalam sediaan gel topikal, tetapi optimasi formula diperlukan untuk menghasilkan sistem nanogel yang ideal.
Evaluation of the Cytotoxic Activity of n-Hexane Fraction of Java Long Pepper (Piper retrofractum Vahl) Leaves Using the Brine Shrimp Lethality Test (BSLT) Method Senti Dwi Suryani; Kony Putriani; Nadya Putri Auliya Serawaidi
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 3 (2026): Volume 4 Nomor 3 September 2026
Publisher : LPPM Universitas Abdurrab

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Java Long Pepper (Piper retrofractum Vahl.) is a plant known to contain various secondary metabolites and exhibit a wide range of biological activities. However, information regarding the cytotoxic potential of the n-hexane fraction from Jawa Long Pepper leaves remains limited. This study aimed to evaluate the cytotoxic activity of the n-hexane fraction from Jawa Long Pepper (P. retrofractum) leaves using the Brine Shrimp Lethality Test (BSLT). Jawa Long Pepper leaves were extracted by maceration using methanol, and the extract was then fractionated by liquid-liquid using n-hexane. The obtained fractions underwent phytochemical screening and were tested for toxicity against Artemia salina larvae at concentrations of 10, 100, and 1000 µg/mL. Larval mortality was observed after a 24 hour incubation period, and the LC₅₀ values were determined using probit analysis. The results showed that larval mortality increased with increasing fraction concentration, with mortality rates of 26.6%, 63.3%, and 96.6%, respectively. The LC₅₀ value for the n-hexane fraction was determined to be approximately 38.1 µg/mL. These results indicate that the n-hexane fraction of P. retrofractum leaves exhibits strong cytotoxic potential against A. salina and may serve as a basis for further research on its active compounds and cytotoxic mechanisms.
Analisis Biaya Pengobatan Pada Pasien Kanker Payudara Bpjs Rawat Inap Di Rsud Arifin Achmad Provinsi Riau nadya putri auliya serawaidi; senti dwi suryani
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 3 (2026): Volume 4 Nomor 3 September 2026
Publisher : LPPM Universitas Abdurrab

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ABSTRAK Kanker payudara merupakan kanker dengan prevalensi tertinggi di Indonesia dan menjadi beban ekonomi yang signifikan, khususnya pada pasien yang menjalani kemoterapi. Penelitian ini bertujuan untuk menganalisis efektivitas biaya pengobatan pasien kanker payudara rawat inap pengguna BPJS di RSUD Arifin Achmad Provinsi Riau pada periode Januari-Juni 2024. Penelitian ini dilakukan secara deskriptif dengan pendekatan retrospektif melalui pengumpulan data rekam medis dan biaya medis langsung sebanyak 90 sampel pasien. Parameter efektivitas yang digunakan adalah lama rawat inap (Length of Stay), sedangkan biaya dihitung dari total Direct Medical Cost. Analisis dilakukan dengan pendekatan Cost Effectiveness Analysis (CEA) menggunakan nilai Average Cost Effectiveness Ratio (ACER). Hasil menunjukkan bahwa terapi antikanker kombinasi lebih banyak digunakan (91%) dibanding terapi tunggal (9%). Regimen kombinasi Docetaxel + Carboplatin merupakan yang paling sering digunakan (20%), sementara terapi tunggal Herzemab mendominasi penggunaannya (6%). Efektivitas terapi ditunjukkan oleh LOS terpendek pada beberapa regimen kombinasi dan tunggal dengan rata-rata 2 hari. Nilai ACER terendah terdapat pada regimen kombinasi Herzemab + Paclitaxel dengan efektivitas 2 hari dan biaya Rp. 5.118.041/hari, menunjukkan sebagai terapi yang paling cost-effective. Hasil ini diharapkan menjadi dasar pertimbangan klinis dan ekonomi dalam pemilihan regimen kemoterapi. Kata Kunci : Kanker payudara, obat anti kanker, efektivitas biaya
Formulation and Evaluation of Capsule Shell from Broiler Chicken Feet Gelatin (Gallus gallus domesticus) Vonny Kurnia Utama; Subardi Bali; Dea Adilla
Jurnal Ilmu Kesehatan Abdurrab Vol. 4 No. 1 (2026): Volume 4 Nomor 1 Maret 2026
Publisher : LPPM Universitas Abdurrab

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Gelatin is a partial hydrolysis protein of collagen found in the skin, white connective tissue and bones of animals. One of the main ingredients that can be used in making capsule shells is gelatin derived from broiler chicken feet. Broiler chicken feet are one of the slaughterhouse wastes (RPA) which consists of skin, bone, muscle and collagen components. The potential of chicken feet to make gelatin can be seen from the collagen protein contain, which is 28,73-36,83% of the total protein. This study aims to determine the evaluation results of capsule shells made from chicken feet gelatin with concentrations of 10 % (F1), 20% (F2), dan 30% (F3). The results obtained from the treatment of capsule shells with concentrations of 10%, 20%, and 30% were tensile strength 4.018±0.72 mPa, 14.09±0.73 mPa, 23.44±5.00 mPa, elongation at break 92.896±7.60%, 21.712±3.86%, 21.636±7.02% and elasticity 4.308±0.57 mPa, 66.946±14.49 mPa, 115±38.57 mPa, respectively. It can be concluded from the results that the capsule shell with 10% broiler chicken feet gelatin concentration the best ability as a capsule shell

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