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Aisyah Nurjanah
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Journal of Indonesian Specialized Nutrition
Published by Ridwan Institute
ISSN : -     EISSN : 30323878     DOI : https://doi.org/10.46799/jisn
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Journal of Indonesian Specialized Nutrition (JISN) is an online journal act as the nutrition and scientific publication platform published by Ridwan Institute. JISN aimed to provide a wide-range knowledge of clinical and community nutrition and health with key focus on maternal, child nutrition and health care, hydration and healthy aging. JISN also publishes original and review articles, expert opinion, consensus, literature review, meta-analysis, brief communication and systematic review as well as commentary focusing on various streams of nutrition and community health sciences including public health and safety sciences and research. JISN also open for special edition and supplement volume publication from all over the world.
Arjuna Subject : Kedokteran - Imonologi dan Alergi
Articles 50 Documents
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CORRELATION OF BODY MASS INDEX WITH ANEMIA IN ADOLESCENT GIRLS AT SECONDARY SCHOOL PGRI 2 JAMBI CITY Aghadiati, Faradina; Sari, Yesi Mustika; Liani Setyarsih; Putri Lubis, Izmi Arisa; Wulandari, Alifah
Journal of Indonesian Specialized Nutrition Vol. 3 No. 3 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i3.47

Abstract

Background: Anemia remains a major public health problem affecting adolescents worldwide, particularly girls who are vulnerable due to rapid growth and menstrual blood loss. In Indonesia, the prevalence of anemia remains high (25–40%), driven by poor dietary habits, low adherence to iron supplementation, and overall nutritional status. While Body Mass Index (BMI)-for-age is a recognized determinant of anemia risk, local evidence, particularly from Jambi City, remains scarce. Methods: This cross-sectional study involved 30 female students aged 15–18 years. The data utilized were collected during a Community Service Program (PKM). BMI for age z-scores were calculated using the WHO 2007 Growth Reference. Hemoglobin levels were measured using a portable hemoglobinometer (HemoCue Hb 301). The relationship between BMI-for-age categories (underweight, normal, overweight) and anemia status was analyzed using the Chi-square test. Results: The overall anemia prevalence was 40%. Based on BMI for age, participants were categorized as underweight (n=8), normal (n=18), and overweight (n=4). Anemia prevalence varied significantly across categories: underweight (75.0%) showed the highest rate, followed by normal (33.3%), and overweight (25.0%). Statistical analysis revealed a significant association between BMI-for-age and anemia (p = 0.041). Conclusions: Anemia was present across all BMI categories, with the highest prevalence among underweight adolescents. These findings indicate that nutritional status strongly influences anemia risk and should be prioritized in adolescent health programs. Integrating school-based strategies such as routine growth and hemoglobin monitoring, iron–folic acid supplementation, and engaging nutrition education.
THE RELATIONSHIP OF DIETARY PATTERNS, PHYSICAL ACTIVITY, AND SCREEN TIME WITH THE INCIDENCE OF OVERWEIGHT AMONG TODDLER AGED 24–59 MONTHS IN SUDIMARA PINANG HEALTH CENTER AREA, TANGERANG CITY Zahra, Audia; Paramita, Farah; Supriyadi; Kurniawan, Agung; Sundjaya, Tonny
Journal of Indonesian Specialized Nutrition Vol. 3 No. 3 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i3.51

Abstract

Background: Overweight in toddlers may further develop into obesity. The Sudimara Pinang Community Health Center area has the highest number of overweight toddlers in Tangerang City. This study aims to examine the relationship between dietary patterns, physical activity, screen time, and the incidence of overweight among toddlers aged 24-59 months in Sudimara Pinang area. Method : This study employed a quantitative approach with a cross-sectional study design. A total of 93 toddlers were purposively selected from the five integrated health posts with the highest number of overweight toddlers. Nutritional status was assessed using anthropometric measurements. Dietary patterns were measured with a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), Physical activity with the Early Year Physical Activity Questionnaire (EY-PAQ), and screen time with the Seven in Seven Screen Exposure Questionnaire. Result: The findings revealed a significant association between dietary pattern (p-value = 0.016), and between physical activity and overweight incidence (p-value = 0.000). However, no significant relationship was found between screen time and overweight (p-value = 0.523). Conclusion: Dietary patterns and physical activity were significantly associated with overweight among toddlers, whereas screen time showed no significant relationship. These findings highlight the need for comprehensive intervention programs in the area, focusing on promoting healthy eating and physical activity.
PROBIOTICS ROLE ON IMPROVING MALNUTRITION IN BOTH UNDER- AND OVERWEIGHT CHILDREN: A NARRATIVE REVIEW Yuniarti, Tricahyani Endah; Piscesa, Saskia; Septiani, Seala; Wijayanti, Elizabeth Anita
Journal of Indonesian Specialized Nutrition Vol. 3 No. 3 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i3.54

Abstract

Background: Malnutrition in children exists at both ends of the spectrum, undernutrition and overnutrition, each with significant health consequences. Probiotics, live microorganisms that confer health benefits when administered in adequate amounts, are being explored as potential interventions through their ability to modulate gut microbiota, enhance nutrient absorption, and regulate immune function. Methods: A narrative review of literatures published between 2004 and 2025 was conducted, covering randomized trials, meta-analyses, and reviews involving probiotics interventions in children. Seventeen key studies were categorized by nutritional status (undernutrition and overnutrition), pediatric health outcomes, and nutritional insights. These studies synthesized and cited into this scientific narration. Results: In undernourished children, probiotics improved weight gain, reduced anemia, enhanced immune responses, and lowered respiratory infection incidence, particularly in low-resource settings. In overweight/obese children, certain Lactobacillus and Bifidobacterium strains improved BMI z-scores and metabolic health. Broader pediatric data support condition-specific benefits of probiotics in gastrointestinal and allergic diseases. Mechanistic evidence highlights bioactive molecules, immune modulation, micronutrient bioavailability, and gut barrier integrity as key pathways. Conclusions: Probiotics have context-specific benefits for pediatric malnutrition, with the strongest evidence in infection reduction and modest growth improvement in undernourished populations. Their role in pediatric obesity is promising but less defined. Strain specificity, dose, and duration remain critical determinants of efficacy, and further high-quality trials are needed.
OPTIMIZING IRON ABSORPTION IN CHILDREN THROUGH VITAMIN C SUPPLEMENTATION AND FORTIFICATION: A REVIEW Aulia, Bianda; Notarianti, Rizna; Larasati, Adisti; Sitorus, Nova Lidia
Journal of Indonesian Specialized Nutrition Vol. 3 No. 3 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i3.55

Abstract

Background: Iron deficiency aeamia is common in children, particularly in low- and middle-income countries, where diets are typically low in bioavailable iron and infections are prevalent. As vitamin C enhances non-heme iron absorption, this review explores current evidence on its role in improving iron status in children. Methods: A narrative literature review was conducted using PubMed, Scopus, and Google Scholar and included studies published from January 2000 to June 2025. Search terms combined keywords related to “vitamin C”, “iron absorption”, “supplementation”, “fortification”, “children”, and “anemia”. Results: Iron absorption in children is influenced by iron form, dietary factors, and developmental stage, with infants and young children at greatest risk of deficiency. Vitamin C is an enhancer of non-heme iron absorption, counteracting inhibitors such as phytates and calcium. Trials combining oral iron with vitamin C supplementation generally showed greater increases in hemoglobin and ferritin compared with iron alone, particularly among children with iron deficiency. Evidence from fortification studies is limited and varies due to differences in study design. Conclusion: Vitamin C co-supplementation might improve iron status in children. However, existing evidence remains insufficient to support specific recommendations for children.
THE RELATIONSHIP BETWEEN LOCAL FOOD-BASED RECOVERY FEEDING AND OTHER FACTORS ON WEIGHT GAIN IN CHILDREN 12-59 MONTHS OF AGE AT PUSKESMAS CIMPAEUN, DEPOK CITY, INDONESIA, IN 2025 Sahara, Ghevira Aulia; Rahmawati, Nurul Dina; Triyanti, Triyanti; Fajrinayanti, Fajrinayanti; Pratiwi, Dessy
Journal of Indonesian Specialized Nutrition Vol. 3 No. 3 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i3.56

Abstract

Background: Malnutrition among children aged 12-59 months remains a major challenge in Indonesia, including in Depok City. Local Food-Based Supplementary Feeding (PMT) is one of the government's intervention efforts to improve or recover children's nutritional status. This study aims to determine the relationship between the provision of Local Food-Based Recovery PMT and other factors on toddler weight gain at the Cimpaeun Health Center in Depok City in 2024. Methods: This study used a cross-sectional design with a quantitative approach. The sample consisted of 71 toddlers aged 12-59 months who were purposively selected. Data were collected through questionnaires and secondary data from the health center. Results: The results showed that 60.6% of toddlers experienced adequate weight gain after participating in the Local PMT program. There was a significant association between the appropriateness of the provision of local PMT and weight gain (p = 0.027; OR = 4.464; 95% CI: 1.155-17.252), meaning that toddlers who received inadequate local food-based recovery PMT had a 4.464 times greater risk of underweight gain compared to toddlers who received inadequate PMT. There was a significant association between infection and weight gain (p = 0.015). Infected toddlers had a higher tendency to gain weight. Meanwhile, variables such as diet, mother's education, knowledge, parenting, posyandu visits, and PHBS did not show a significant relationship with toddler weight gain. Conclusions: The provision of an appropriate local food-based recovery PMT and the health condition of the child are the factors most associated with under-five weight gain. Other factors such as infection may encourage more attention from parents, which contributes to children's nutritional recovery.
THE RELATIONSHIP BETWEEN MATERNAL NUTRITIONAL STATUS AND EXCLUSIVE BREASTFEEDING STATUS WITH INFANT WEIGHT GAIN IN THE SITUBONDO HEALTH CENTER AREA Nadiro; Paramita, Farah; Supriyadi; Kurniawan, Agung; Wulandari, Alifiah
Journal of Indonesian Specialized Nutrition Vol. 3 No. 4 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i4.63

Abstract

Background: Infant weight gain is a key indicator for monitoring growth and is influenced by various factors, including maternal nutritional status and breastfeeding practices. Based on the data, it is still found that the low percentage of infants with weight gain and exclusive breastfeeding coverage has not reached the target. This study aims to investigate the relationship between maternal nutritional status and breastfeeding status, with the weight gain of infants aged 1-6 months in the Situbondo Health Center area. Method: This study uses a cross-sectional analytical design involving a sample of 70 breastfeeding mothers with infants aged 1-6 months, selected from 18 posyandu. Data were analyzed using the Chi-square test. Result: The findings showed that 55.7% of infants received exclusive breastfeeding, and 62.9% achieved weight gain in accordance with the Weight-for-Age Growth Curve. There is a significant relationship between breastfeeding status (p = 0.013), maternal nutritional status based on BMI (p = 0.018), and maternal nutritional status based on MUAC (p = 0.001) with infant weight gain. Conclusion: Maternal nutritional status (BMI and MUAC) and exclusive breastfeeding play a key role in supporting optimal weight gain in infants aged 1–6 months.
FACTORS ASSOCIATED WITH THE INCIDENCE OF ANEMIA IN PREGNANT WOMEN IN INDONESIA: ANALYSIS OF INDONESIAN HEALTH SURVEY (SKI) 2023 DATA Putri, Jessica Reitanya; Pujonarti, Siti Arifah; Syafiq, Ahmad; Achadi, Endang Laksminingsih; Perkasa, Al Ilham Ksatria Gagah; Basrowi, Ray Wagiu
Journal of Indonesian Specialized Nutrition Vol. 3 No. 4 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i4.64

Abstract

Anemia is a common nutritional issue among vulnerable populations, including toddlers, adolescents, women of reproductive age, and pregnant women. Anemia in pregnant women impacts both the mother and fetus. For the mother, it reduces quality of life and can lead to mortality. Babies born to anemic mothers are at risk of congenital abnormalities, stillbirth, and stunting. Maternal health issues during pregnancy affect the critical first 1000 days of a child's life, with permanent consequences for survival, necessitating appropriate interventions to minimize these risks. The 2023 SKI Report indicates a 27.7% prevalence of anemia among pregnant women in Indonesia, classified as a moderate public health issue. This study is a quantitative study using a cross-sectional design aimed to identify factors associated with anemia in pregnant women in Indonesia in 2023, utilizing secondary data from the 2023 SKI. The dependent variable was anemia, with independent variables from socio-demographic factors, lifestyle factors, dietary patterns, and pregnancy-related factors. Data analysis used complex samples, including univariate and bivariate analyses with chi-square tests. The study found significant associations between anemia in pregnant women and consumption of meat, poultry, and their processed products (p-value = 0.047), pregnancy interval (p-value = 0.033), and consumption of supplementary feeding (PMT) (p-value = 0.001) in Indonesia in 2023.
A NARRATIVE REVIEW ON THE PROTECTIVE MECHANISM OF PROBIOTICS TO COMMUNICABLE DISEASES AMONG CHILDREN IN ASIA Piscesa, Saskia; Yuniarti, Tricahyani Endah; Wijayanti, Elizabeth Anita
Journal of Indonesian Specialized Nutrition Vol. 3 No. 4 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i4.66

Abstract

Background: Communicable diseases remain a major cause of morbidity among children in Southeast Asia, where malnutrition, environmental enteric dysfunction, and limited sanitation increase susceptibility to infection. Probiotics have gained attention as a nutrition-based strategy capable of improving gut health, enhancing immunity, and reducing pathogen burden. This narrative review summarizes the protective mechanisms of probiotics and their relevance for child health in Indonesia and neighboring countries. Methods: A comprehensive literature search was conducted in PubMed, Scopus, and Google Scholar for studies published from January 2004 to February 2025. Search terms included “probiotics,” “children,” “communicable diseases,” “gut microbiota,” “malnutrition,” and “synbiotics.” Inclusion criteria were: pediatric populations (0–18 years), probiotic interventions, and outcomes related to infection, intestinal integrity, immune function, or nutritional status. Fourteen core studies (RCTs, systematic reviews, meta-analyses, and narrative reviews) met criteria, and five additional sources were used for epidemiological and conceptual background. Results: Evidence across Indonesia, Vietnam, Malaysia, China, India, and Thailand shows that probiotics improve gut microbiota diversity, reduce pathogenic colonization, strengthen tight-junction expression, and enhance mucosal immunity. Clinical benefits include reduced incidence and duration of diarrhea and respiratory infections, improved recovery reflected in increased appetite and weight gain, reduced antibiotic prescriptions, and decreased school absenteeism. Probiotics were feasibly delivered through fortified milk, yogurt, supplements, and school-based nutrition platforms, aligning well with existing child-health programs. Conclusion: Probiotics offer a safe, nutrition-focused intervention that helps mitigate the infection–malnutrition cycle in children. By supporting gut integrity and immune maturation, probiotics complement established nutrition strategies. Integrating probiotics into routine child nutrition and infectious-disease prevention programs may provide meaningful public health benefits, though long-term and multi-strain studies are needed to guide scalable implementation.
IRON DEFICIENCY IN EARLY LIFE AND LATER BEHAVIORAL OUTCOMES: A SYSTEMATIC REVIEW Latifah, Suci; Septiani , Seala; Kusuma, Refani Alycia; Pratiwi, Dessy
Journal of Indonesian Specialized Nutrition Vol. 3 No. 4 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i4.67

Abstract

Background: Iron deficiency during early life is the most common micronutrient deficiency worldwide and may have lasting effects on neurodevelopment and behavior. This systematic review aimed to explore the relationship between iron deficiency in infancy (0–24 months) and behavioral outcomes beyond two years of age. Methods: This study was a systematic literature review of twenty-three articles. These articles were sourced from scientific journal articles on ScienceDirect, covering studies published between 2005 and 2025. Inclusion criteria were longitudinal cohort or randomized controlled trials assessing behavioral outcomes such as attention, hyperactivity, and socio-emotional regulation. Results: Early-life iron deficiency was consistently associated with increased internalizing and externalizing behaviors, attention deficits, and symptoms of ADHD and Sluggish Cognitive Tempo persisting into adolescence. Timing and severity of deficiency influenced outcomes, with prenatal deficiency affecting recognition memory and executive function, while infant deficiency predicted behavioral dysregulation and academic difficulties. Targeted iron supplementation reduced behavioral problems, whereas excessive or non-individualized supplementation showed limited benefits. Conclusions: Iron deficiency in early life has long-term behavioral consequences. Early detection and individualized interventions are crucial for preventing neurobehavioral impairments and optimizing child development.
THE GUT-BRAIN-MICROBIOME AXIS IN CHILDHOOD OBESITY: MECHANISMS AND CLINICAL IMPLICATIONS Aulia, Bianda; Sundjaya, Tonny
Journal of Indonesian Specialized Nutrition Vol. 3 No. 4 (2025): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63953/jisn.v3i4.69

Abstract

Background: Childhood obesity has become a global health crisis affecting 188 million children aged 5–19 years worldwide, with serious metabolic complications. The gut–brain–microbiome axis has emerged as a key mechanistic link and therapeutic target for obesity in children. Methods: A narrative literature review was conducted using PubMed, Scopus, and Google Scholar and included studies published up to December 2025. Search terms, used in various combinations, included “childhood obesity,” “gut microbiota,” “gut–brain axis,” “targeted interventions,” “probiotic,” and “prebiotic”. Results: Childhood obesity is associated with early-life gut dysbiosis characterized by reduced diversity, higher Firmicutes/Bacteroidetes ratios, and shifts in key taxa, driven by prenatal, postnatal, and lifestyle factors. This dysbiotic microbiota enhances energy harvest, promotes low-grade inflammation and barrier dysfunction, and disrupts gut–brain axis signaling via altered short-chain fatty acids, neurotransmitter, and gut hormone profiles, thereby impairing appetite regulation and favoring positive energy balance. Emerging evidence indicates that targeting the gut microbiota–brain axis with probiotics, prebiotics, synbiotics, and fecal microbiota transplantation may improve metabolic outcomes and body composition in children with obesity. Conclusion: Gut microbiota dysbiosis contributes to childhood obesity via altered metabolism, inflammation, and gut–brain axis–mediated appetite regulation.

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