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Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Published by SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA
ISSN : 2443115X     EISSN : 24771821     DOI : https://doi.org/10.51352/jim
Core Subject : Health, Science,
Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal Ilmiah Manuntung is a journal on pharmaceutical and health sciences published by Sekolah Tinggi Ilmu Kesehatan Samarinda which includes the study of pharmaceutical sciences, medicine, synthetic organic chemistry, organic chemistry of natural materials, biochemistry, analytical chemistry, physical chemistry, biology, microbiology, tissue culture, botany and animals related to pharmaceutical products, nursing, midwifery, health analysts, nutrition and public health.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 326 Documents
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: GAMBARAN PENGGUNAAN ANTIBIOTIK PADA PASIEN ULKUS DIABETIKUM DI INSTALASI RAWAT JALAN PENYAKIT DALAM RSUD ULIN BANJARMASIN PERIODE JULI – DESEMBER 2018 Saftia Aryzki; Merry Alicia; Siti Rahmah
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.373

Abstract

Diabetic ulcers are a disease that is experienced by many people with diabetes mellitus, open wounds on the skin surface of the diabetic ulcer have the potential to develop into infection, to deal with the problem of infection needed the right treatment, one of them is by using antibiotics. The purpose of this study was to describe the use of diabetic ulcer patients In Installation Of Outpatient in RSUD Ulin Banjarmasin Period July-December 2018. This study is a non-experimental study with a descriptive type of study through a retrospective search for outpatient prescription for diabetic ulcers. This research was conducted in April-May 2019 in Installation Of Outpatient in RSUD Ulin Banjarmasin. Sampling is done by saturation sampling method, the population in this study were 254 prescrptions. While the sample in this study were 228 prescrptions that met the criteria of inclusion and exclusion. The data obtained is copied to the observation sheet, after the data collected is then entered into a computer and a calculation is carried out to find out the percentage of each factor studied and finally the data will be presented in table form. The results obtained from the study of 228 prescriptions of diabetic ulcer patients obtained the use of single antibiotics as much as 182 (79.82%) and combination antibiotics by 46 (20.18%). The single most prescribed group of antibiotics is the Makrolide group of 49.56%, the Makrolide group which is often prescribed namely Clindamycin 300 mg as much as 39.91%.While the most prescribed combination of 2 antibiotics is Clindamycin 300 mg + Metronidazole 500 mg 14.47%.
UJI STABILITAS DAN IRITASI FORMULA KRIM ANTI NYERI EKSTRAK ETANOL DAUN KELOR (Moringa oleifera) Amriani Sapra; Suwahyuni Mus; Rifka Malluka; Dwirandy Dwirandy
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.380

Abstract

Moringa oleifera leaf contains quercetin act as an analgesic by inhibiting cyclooxygenase and lipooxygenase. These enzymes interfere synthesis of prostaglandins by arachidonic acid and lead to reduce pain. This study aimed to obtain a physically stable M/A cream formula from the lyophilized ethanol extract of Moringa leaf and to determine the irritation effect. The cream prepared with variations of cetyl alcohol concentration F1 (2%), F2 (4%,) and F3 (6%). The cream stability was determined with organoleptic, homogeneity, type of emulsion, pH, viscosity, and spreadability parameters after accelerated condition. The Irritancy test was determined to the Albino Oryctolagus cuniculus. The results showed that F1 has the best stability than F2 and F3 and showed irritation index 0,5 classified as moderate irritation.
PEMBUATAN STRIP TEST DAN IDENTIFIKASI FENILBUTAZON PADA JAMU PEGAL LINU Henny Nurhasnawati; Triswanto Sentat; Adi Prasetiyo
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.383

Abstract

Jamu (Indonesian herbal medicine) are prohibited from containing chemicals medicine which are isolated or synthetic chemical compounds. Chemical compounds which is commonly added in jamu pegal linu (rheumatic pain) is phenylbutazone. One simple alternative test for detecting chemicals medicine content is to use a strip test. The purpose of this study was to determine the presence or absence of phenylbutazone content in jamu using a strip test. The research conducted is experimental research. This study used 6 samples of jamu pegal linu which were extracted using 95% ethanol solvent. The strip test is carried out by immobilizing reagents into Whatman’s filter paper using the impregnation method. Data obtained from observations of the color change of the strip test. The results showed that strip test made with alizarin red reagent and potassium hexacyanoferate (III) identified 2 samples of jamu pegal linu containing phenylbutazone, namely sample D and E, from 6 samples that circulated in Sungai Pinang District, Samarinda.
UJI POTENSI EKSTRAK DAUN BENALU BATU (BEGONIA SP) TERHADAP KADAR GLUKOSA DALAM DARAH DAN GAMBARAN HISTOPATOLOGI PANKREAS TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) Joni Tandi; Dela Erni Paerunan; Nurifa Nurifa; Yunlis Silintowe Kenta; Sri Mulyani
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.384

Abstract

This study aims to determine the potential for glucose levels in the blood of ethanol extracts of the begonias (Begonia Sp.), the effect of the extract on the pancreatic histopathology of white rats (Rattus norvegicus) which was induced by streptozotocin, and the effective dose begonias’ extract leaves on the histopathological descriptions of pancreatic male white rats. This study was an experimental laboratory where the research group consisted of group I (the control group) as a normal control was given a standard feed, group II (negative control) was given a 0.5% Na CMC suspension, group III (positive control) was orally given glibenclamide and experimental groups IV, V, and VI (doses 50, 100, and 200 mg/kg BW). Were given ethanol extract of begonias leaves. The results showed that the ethanol extract of the begonias (Begonia Sp.) contained secondary metabolite compounds, namely flavonoids, alkaloids, saponins, polyphenols, and tannins. Ethanol extract of begonias leaves at adose of 50 mg/kg BW was an affective dose in reducing blood glucoselevels by an avarage of 101,8 mg/dL) and a dose of 50 mg/kg BW can affect the histopathological picture of the pancreas in STZ induuced rats with an average damage value of 2 from a maximum of 4.
UJI AKTIVITAS EKSTRAK ETANOL DAUN EKOR NAGA (Rhaphidophora pinnata (L.f.) Schott.) SEBAGAI ANTIHIPERURISEMIA TERHADAP MENCIT PUTIH JANTAN Bella Pascila; Fathnur Sani K; Revis Asra; Agung Giri Samudra
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.389

Abstract

Hyperuricemia is a condition of abnormal health hence increasing urid acid level within blood that is up in normal value spesificaly for man is over 7,0 mg/dL and for woman is over 6,0 mg/dL. Ekor naga leaves (Rhaphidophora pinnata L.f.) have some second metabolic compound namely flavonoid and alkaloid that have a capability to hampering xhantine oxidase enzyme. The objective of this reseach is to know the effectiveness giving ethanol extract of ekor naga leaves for decreasing urid acid level and to know the effectiveness dose ethanol extract of ekor naga leaves for decreasing uric acid level. The sample of this reseach was ethanol extract of ekor naga leaves, allopurinol as positive control, chicken liver juice and potassium oxonate as inductioun of hyperuricemia. The design of this research is complete random design with 5 action where in one action consist of 5 mice. The group of action was K+ Allopurinol 0,26mg/kgBB, P1 extract 125mg/kgBB, P2 extract 250mg/kgBB, and P3 extract 375mg/kgBB. The best dose is dose II (250mg/kgBB) with percentage of decreasing uric acid is 45,22%. Than dose III (375 mg/kgBB) with perfentage of dereasing urid acid is 44,66%, and dose I (125 mg/kgBB) with percentage of the decreasing uric acid is 39,60%. Moreover, it can be concluded that all dose of ethanol extract ekor naga leaves have an activity as antyhiperuricemia.
EFEKTIVITAS DAN KEAMANAN TERAPI NATRIUM DIKLOFENAK DAN PIROKSIKAM PADA PASIEN OSTEOARTHRITIS DI PUSKESMAS KOTA SURABAYA: PERBANDINGAN EFEKTIVITAS DAN KEAMANAN NATRIUM DIKLOFENAK DAN PIROKSIKAM PADA PASIEN OSTEOARTHRITIS Selly Septi Fandinata; Anita Purnamayanti; Primanitha Ria Utami
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.392

Abstract

Osteoarthritis (OA) is a disorder affecting the diarthrodial joints that support the skeletal system and the axial causing joint symptoms. The effectiveness of NSAID pain therapy in osteoarthritis often results in inadequate response and prolonged use can cause unexpected side effects. The therapy offered is diclofenac sodium and piroxicam. This research used the design of Quasy Experimental Design type Non Equivalent Control Group Design. The research was conducted at Puskesmas Tenggilis Surabaya. The outcomes measured as the intensity of pre and post treatment pain, Drug Side Effects on pre and post-treatment kidney function, and side effects on pre and post-treatment blood pressure. The study sampled 42 patients consisting of 20 patients (piroxicam group) and 22 patients (sodium diclofenac group). There was a significant difference with the intensity of the pain scale in both post groups (p= 0.001). There were no significant differences in average creatinine and BUN in the post treatment of pyroclacycam group and post treatment group sodium diclofenac (p = 0.772) and (p = 0.801). This study shows that the piroxicam group is more effective in reducing the pain scale than sodium diclofenac and both groups have not been shown to be safety in renal function (Creatinine and BUN)
PENGUJIAN EFEKTIFITAS FORMULA GEL EKSTRAK DAUN BELUNTAS (Pluchea indica (L.) Less) DENGAN VARIASI KONSENTRASI GELLING AGENT SEBAGAI KANDIDAT SEDIAAN ANTI JERAWAT Andi Ulfah Magefirah Rasyid; Zahira Amody
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.393

Abstract

Beluntas (Pluchea indica (L.) Less) is a plant that is often used in traditional medicine because of the presence of several substances that have activity as antimicrobial compounds. Beluntas leaves contain secondary metabolite compounds such as flavonoids, alkaloids, tannins, steroids, terpenoids and saponins which can function as antibacterial. This experimental research aimed at obtaining beluntas leaf extract gel and to determine the physical stability and the effectiveness of beluntas extract gel against Propionibacterium acnes. The first step is drying the beluntas leaves and and extracted by maceration method with 70% ethanol solvent. The extract obtained was then formulated into a gel and evaluated, the evaluation results show that formula 1 is the most stable. The results showed that beluntas leaf extract gel was effective in inhibiting the growth of Propionibacterium acnes, the inhibition zone obtained was categorized as strong, where the average diameter before the accelerated stability test was 12.02 mm and 11.58 mm after the accelerated stability test.
AKTIFITAS ANTIBAKTERI DARI SEDIAAN FOOTSANITIZER SPRAY KOMBINASI EKSTRAK BIJI KOPI (Coffea) DAN RIMPANG JAHE (Zingiber officinale) Wilda Amananti; Dairoh Dairoh
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.394

Abstract

Foot deodorizing products currently circulating include anti-bacterial soaps, foot soaking powders, anti-prespirants, creams, and foot odor powders. However, these preparations have not been sold freely in Indonesia. In terms of use, it is considered impractical, because they have to use water when used. The product is considered ineffective, so there is a need for an innovation to remove foot odor that is healthy, more practical, and effective, namely Footsanitizer Spray. However, Footsanitizer Spray preparations in the market contain 70-95% alcohol. Excessive use of alcohol and chemicals can have health effects and irritant effects on the skin. Coffee has properties that are known to get rid of bad odors. Ginger rhizome (Zingiber officinale Roscoe) has been known to have antibacterial activity because it contains phenols, flavonoids, terpenoids, and essential oils. So that the combination of coffee bean extract and ginger rhizome is taken into consideration in making Footsanitizer Spray. Footsanitizer Spray in this study was made into 3 formulas. The difference in the formula is based on the comparison of the concentration of coffee bean extract and ginger root. Formula 1 with 25%: 45% coffee bean and ginger extract. Formula 2 with a ratio of 35%: 35% coffee bean extract and ginger rhizome. Formula 3 with a ratio of 45%: 25% coffee bean extract and ginger root. Based on the results of organoleptic testing and homogeneity, all formulas have a light brown color liquid with a distinctive aromatic smell. And soft taste. All formulas also produce homogeneous preparations. The results of the specific gravity test of the three formulas have not much different density. Namely, formula 1, formula 2 and formula 3 respectively are 1.064 gr / ml, 1.065 gr / ml, and 1.062 gr / ml. while the viscosity values ​​were 1.56 cp, 1.6 cp, and 1.61 cp, respectively. Formula 2 with a concentration of 35%: 35% has better antibacterial activity than other formulas. And it is included in the moderate barrier response category.
ANALISIS SANITASI KAPAL DENGAN TANDA KEBERADAAN KECOA PADA KAPAL PENUMPANG DI KANTOR KESEHATAN PELABUHAN KELAS II SAMARINDA Ratna Yuliawati; Wisnu Adi Prasetyo; Vita Pramaningsih; Rusdi Rusdi
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 7 No. 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.400

Abstract

Ship sanitation is one of the efforts aimed at environmental health risk factors on board. The results obtained from the Port Health Office (KKP) Class II Samarinda, there are several types of ships that are routinely carried out sanitary inspections of ships, one of which is a passenger ship. Therefore, researchers want to examine the Sanitary Relationship of Ships With Signs of The Presence of Cockroaches On Passenger Ships Leaning in The Port of Class II Samarinda. The design of this study is an observational analytical method with cross sectional study design. The instruments in this study used the ship's sanitation inspection form and the cockroach inspection form on the passenger ship. The data is processed using Fisher Exact Test. Based on the results of the study, where the 5 vessels that were examined have met the sanitary requirements (100%) in accordance with The Minister of Health Regulation No. 40 of 2015 concerning Certificate of Ship Sanitation. The results of the study found signs of the presence of cockroaches on the ship as many as 4 units of ships (80%). The results of statistical tests processed by Fisher Exact Test obtained the following results, p-value count = 0.20 > from p-value α = 0.05 so that the conclusion H0 received, which means "No Relation to Ship Sanitation with Signs of The Presence of Cockroaches On Ships Leaning in Samarinda Port".
Pengaruh Penggunaan Media Sangrai Pasir Putih dan Pasir Hitam Terhadap Karakteristik Rendemen dan Bilangan Asam Minyak Kemiri Dari Daerah Asal NTT. Silvana Kholid Bahadi; Aldi Budi Riyanta; Purgiyanti Purgiyanti
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 7 No. 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.401

Abstract

Candlenut (Aleurites Moluccana (L.) Willd) is a plant commodity that has the potential to be developed. Candlenut processing also varies, one of which is that candlenut oil can be made and then its benefits can be taken. In making the candlenut oil, it uses the oil press method with a press machine that has previously been roasted using black sand or white sand media. The characteristics of the candlenut oil include yield and acid number. The yield of hazelnut oil on black sand is 47.55% and on white sand is 46.80%. And the results of the acid number on black sand are 1.8% while on white sand is 2.1%. Based on these results, it can be concluded that the use of black sand and white sand as a roasting medium affects the yield characteristics and acid number of candlenut oil.

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