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Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Published by SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA
ISSN : 2443115X     EISSN : 24771821     DOI : https://doi.org/10.51352/jim
Core Subject : Health, Science,
Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal Ilmiah Manuntung is a journal on pharmaceutical and health sciences published by Sekolah Tinggi Ilmu Kesehatan Samarinda which includes the study of pharmaceutical sciences, medicine, synthetic organic chemistry, organic chemistry of natural materials, biochemistry, analytical chemistry, physical chemistry, biology, microbiology, tissue culture, botany and animals related to pharmaceutical products, nursing, midwifery, health analysts, nutrition and public health.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 326 Documents
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UJI AKTIVITAS ANTI BAKTERI LARUTAN DISINFEKTAN ALAMI INFUSA DAUN SIRIH (Piper Betle L.) TERHADAP Staphylococcus aureus Nori Wirahmi; Muhammad Ichsan Triansyah; Zul Amri; Camelia Putri Masrijal
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 7 No. 2 (2021): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i2.522

Abstract

This study is a test of the anti-bacterial activity of natural disinfectant solution of betel leaf infusion (Piper Betle L.) against staphylococcus aureus. This study aims to determine the anti-bacterial activity of betel leaf infusion disinfectant solution against staphylococcus aureus. This study used the disc diffusion method by looking at the inhibition area in the presence of a clear area around the disc. The betel leaf infusion concentration used was 60% w/v and 90% w/v. The analysis used is descriptive analysis. The results of this study indicate that betel leaf infusion with a concentration of 90% w/v is better than betel leaf infusion with a concentration of 60% w/v. Betel leaf infusion concentrated 90% w/v had an inhibition area of ​​6.66 mm and betel leaf infusion concentrated 60% w/v had an inhibition area of ​​2.13 mm. The 90% w/v concentration of betel leaf infusion is included in the moderate anti-bacterial category and 60% w/v concentrated betel leaf infusion is in the weak category. Betel leaf infusion can be used as a natural disinfectant and is safe to use.
TINGKAT PERILAKU PENGOBATAN, KEPATUHAN MINUM OBAT, DAN KADAR GULA DARAH PASIEN DIABETES MELLITUS RAWAT JALAN DI RSUD BRIGJEND. H. HASAN BASRY KANDANGAN Novia Ariani; Riza Alfian; Erna Prihandiwati
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.523

Abstract

Diabetes mellitus is a metabolic disorder of the body that arises in a person because of an increase in blood sugar levels above the normal value. The case of diabetes mellitus in Indonesia is ranked 7th in the world with the number of patients as many as 8.5 million people. The level of treatment behavior, the level of medication adherence, and blood sugar levels is a critical determinant of the success of diabetes mellitus therapy.The research was conducted by using observational method. Sampling was done by consecutive sampling method. Samples meeting the inclusion criteria were 153 patients. The inclusion criteria in this study were DM patient in RSUD Brigjend. H. Hasan Basry Kandangan at the age of 18 - 65 years and willing to follow the research by filling informed consent first. Exclusion criteria were DM patients with deaf, illiterate, and recurrent patients. Data collection was done by filling out KAP-DM and MARS questionnaires, blood glucose data obtained from patient's medical records. The data of the research are presented in descriptive form using frequency distribution test.The results showed that the sample with preset treatment treatment rate was 22.2%; contemplation of 39.2%; preparation of 18.3%; and the action amounted to 20.3%. The results of drug adherence compliance analysis showed low adherence medication level of 2.0%, moderate 55.6% and high 42.4%. Blood sugar levels of controlled samples were 35.3% and uncontrolled were 64.7%.Based on the results of the study it can be concluded that the sample is dominated by the level of behavior of contemplative treatment, the level of medication adherence was medium, and uncontrolled blood sugar levels
IDENTIFIKASI DAMPAK INTERAKSI OBAT ANTIHIPERTENSI TERHADAP TEKANAN DARAH PADA PASIEN GERIATRI HIPERTENSI YANG DIRAWAT INAP DI RSUD DR SOEDARSO PONTIANAK Muhammad Akib Yuswar; Egida Rachmadani; Eka Kartika Untari
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.524

Abstract

Hypertension is one of cardiovascular diseases in geriatrics. Hypertensive geriatric patients require a combination of more antihypertensives to achieve blood pressure targets, it can cause high risk of polypharmacy. Polypharmacy in hypertensive geriatric patients is at high risk of drug interactions that can affect their blood pressure. This study aims to identify the interactions of antihypertensives based on mechanism and severity and also to determine whether there is a change in blood pressure caused by drug interactions in geriatric hypertensive inpatients at RSUD Dr Soedarso on January – June 2019. Data were collected retrospectively from 38 patients’ medical records, using total sampling technique. Data were analyzed descriptively using E-book Stockley’s Drug Interaction and Drug Interaction Checker on medscape.com, drugs.com. There were 28 patients (73%) who may experience drug interactions with a total of 85 cases. Drug interactions with moderate severity and pharmacodynamic interaction mechanism often occur in a row were 61 cases (72%) and 79 cases (93%). There were a decrease and increase blood pressure, which in a row were 23 and 4 patients. The decrease of patients’ blood pressure estimated caused by synergistic drug interactions of antihypertensives and adjustment of each drug dose that has potential to increase blood pressure.
FORMULASI DAN EVALUASI MASKER GEL PEEL-OFF EKSTRAK MINYAK BUAH MERAH PAPUA (Pandanus conoideus Lam) UNTUK PERAWATAN KULIT WAJAH Fajar Setiawan; Saka Bekti Subagja; Anna Yuliana; Lusi Nurdianti
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 7 No. 2 (2021): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i2.525

Abstract

Papua red fruit (Pandanus conoideus Lam) is one species of the genus Pandanus that grows naturally almost all over the land of Papua that has strong antioxidant potential that is widely applied in skin care. The purpose of this study was to find out the formulation of preparation making and evaluation of peel-off gel masks using variations in the concentration of papua red fruit oil extract. Methods used to make peel-off gel mask formulas to obtain high-quality preparations through evaluation stages include organoleptic testing, homogeneity, pH, spread test, dry power test, skin irritation test, viscosity test, and hedonic testing. The results showed that the preparation of peel-off gel mask extract of papua red fruit oil was successfully developed with good physical stability from the results of evaluation testing. The best peel-off gel mask formula in the study was a formula with a concentration of Papua red fruit oil extract of 0.5%b/v.
PENGARUH DUKUNGAN KELUARGA TERHADAP KEPATUHAN MINUM OBAT PASIEN HIPERTENSI DI PUSKESMAS MUARA WIS Sri Endah Handayani; Husnul Warnida; Triswanto Sentat
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.527

Abstract

One of the public health concerns is drug non-adherence. The main cause of poor hypertension control is noncompliance with antihypertensive medications. The elements that drive compliance behavior are numerous and complicated, with social support being one of them. Family support is critical in health care since it is through family support that a healthy family can be achieved. Family members can help by providing information about their sickness or reminding them to take their medications. The goal of this research was to identify the relationship between family support and medication adherence in hypertensive patients at Muara Wis Health Center, Kutai Kartanegara Regency, Province East Borneo. This study is descriptive correlational and uses a cross-sectional method, which involves measuring or observing at the same time and the same location. The participants in this study were 100 hypertensive patients of Muara Wis Health Center. The data in this study were analyzed using Spearman rank correlation. Based on the MMAS (Morisky Medication Adherence Scale) questionnaire, medication adherence in hypertensive patients at the Muara Wis Health Center had 52 percent low adherence, 29 percent moderate adherence, and 19 percent high adherence. According to pill count, low adherence patients was 51 percent, moderate adherence was 29 percent, and high adherence was 20 percent. Patients with hypertension who had poor family support were 54 percent, those who received moderate family support were 26 percent, and those who received strong family support were 20 percent. Hence, there is a significant relationship between family support and medication adherence in hypertensive patients of Muara Wis Health Center.
UJI INHIBITOR ENZIM TIROSINASE EKSTRAK DAN FRAKSI DAUN KEDABU (Sonneratia ovata Backer) SECARA IN-VITRO Mustika Furi; Ainun Alfatma; Rahma Dona; Armon Fernando; Fina Aryani; Rahayu Utami; Septi Muharni; Husnawati; Wira Noviana Suhery; Melzi Octaviani
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.529

Abstract

Kedabu leaves (Sonneratia ovata Backer) are known contain secondary metabolites, one of which is phenolic, flavonoid and antioxidant activity. Phenolic, flavonoids and antioxidant are known to inhibit the tyrosinase enzyme. The tyrosinase enzyme is involved in the process of melanogenesis which produces melanin. Melanin can cause hyperpigmentation. To prevent hyperpigmentation, tyrosinase inhibitors are needed. This study aimed to test the tyrosinase enzyme inhibitor in ethanol extract, n-butanol fraction, ethyl acetate fraction, n-hexane fraction of kedabu leaf (Sonneratia ovatta Backer) using L-tyrosine as a substrate. The method used to get ethanol extract using ethanol maceration, while some fractions are obtained using the fractionation method. The test was carried out using L-tyrosine and kojic acid as a positive control with absorption measurements using microplate reader at a wavelength of 492 nm. The results showed that the best tyrosinase inhibitory activity was produced by the ethyl acetate fraction with an IC50 value of 18,82 g/mL, followed by the n-butanol fraction with an IC50 value of 24,42 g/mL, and the n-hexane fraction with an IC50 value. 28,77 g/mL, ethanol extract with an IC50 value of 99,09 with a strong category for all samples compared with kojic acid as a positive control with an IC50 value of 30,09 g/mL.
TINGKAT KEPUASAN MASYARAKAT TERHADAP PELAYANAN PENGGALIAN INFORMASI SWAMEDIKASI OLEH PETUGAS APOTEK PADA MASA PANDEMI COVID-19 DI KECAMATAN TUAH MADANI KOTA PEKANBARU TAHUN 2021 Septi Muharni; Putri Zulnandita; Fina Aryani; Rahayu Utami; Mustika Furi
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.530

Abstract

Self-medication is an effort made to overcome complaints or pain by using medicines purchased without a doctor's prescription. One of the stages in this self-medication is extracting information. Information gathering aims to collect or dig up information from patients regarding the symptoms experienced by patients so that pharmacy staff are assisted in making decisions and recommending the correct therapy for patients. To determine the quality of information mining services, one way is to find out the community's satisfaction with the self-medication information mining service. Satisfaction is an important part of health services because respondent satisfaction cannot be separated from the quality of health services. The purpose of this study was to determine the level of community satisfaction with the service of extracting information on self-medication and providing drug information by pharmacists during the COVID-19 pandemic in the Tuah Madani sub-district, Pekanbaru City in 2021 based on five (5) dimensions of service quality, namely reliability, responsiveness, empathy, assurance and tangibles. This research is observational/survey research with a descriptive research design using quantitative analysis. Sampling was done by non-probability sampling method on 100 respondents. The results showed that respondents' satisfaction was in the aspect of reliability 66%, responsiveness 76.2%, empathy 74.4%, assurance 75.25% and tangibles 82.12%. This shows that the community as a whole is satisfied with the services provided by pharmacists.
GAMBARAN PENGETAHUAN MASYARAKAT TENTANG PENGGUNAAN MULTIVITAMIN DAN SUPLEMEN KESEHATAN SELAMA PANDEMI COVID-19 Fina Aryani; Desmalia Desmalia; Husnawati Husnawati; Septi Muharni; Mira Febrina; Anugrah Humairah
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.532

Abstract

Increasing number of cases of COVID-19 currently requiring the community to make more efforts to carry out various preventive efforts. One of the efforts that can be done to prevent COVID-19 is to maintain and increase the body's immunity which can be assisted by the use of multivitamins and health supplements. This study aims to examine public knowledge about the use of multivitamins and health supplements in Pekanbaru family pharmacies during the COVID-19 pandemic. This research is a descriptive observational study with concurrent data collection techniques through online questionnaires. The sampling technique in this study was carried out by non-probability sampling with purposive sampling method. The sample in this study is the people of Pekanbaru City who meet the inclusion criteria with a total of 110 respondents. Data analysis in this study used univariate analysis which aims to explain or describe the characteristics of each research variable, so that the results obtained that people who have good knowledge are 54.64%, people who have sufficient knowledge are 43.63%, and people who have good knowledge have less knowledge is as much as 1.81%. The high percentage of respondents with good knowledge shows that most people in Pekanbaru City already have good knowledge about the use of multivitamins and health supplements during the COVID-19 pandemic.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN SEDIAAN BODY BUTTER EKSTRAK ETANOL UMBI BIT (Beta vulgaris L.) DENGAN METODE DPPH Repining Tiyas Sawiji; Elisabeth Oriana Jawa La
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.533

Abstract

Beetroot (Beta vulgaris L.) is a plant that contains betasianin (purple pigment) and betasantin (yellow pigment) which makes the color of beets dark red to purplish. The fruit contains a small amount of flavonoid compounds (anthocyanins) which have antioxidant activity. This study aims to develop a body butter formulation of ethanol extract of beetroot (Beta vulgaris L.) as an antioxidant and to see the antioxidant activity with the DPPH immersion method. Extraction of beets used the maceration method using 70% ethanol as a solvent. The antioxidant activity test formula was measured using UV-Vis spectrophotometry with a wavelength of 520 nm. The results showed that formula I obtained an IC50 value of 240 µg/mL (AAI = 0.16), formula II obtained an IC50 value of 139.93 µg/mL (AAI = 0.28), and formula III obtained an IC50 value of 133.34 µg/mL (AAI = 0.29). The higher the antioxidant concentration of the fruit ethanol extract body butter preparation, the smaller the IC50 value, and the greater the AAI value obtained. Based on the results obtained, the antioxidants from the beetroot ethanol extract body butter were still able to fight free radicals at a weak level.
FORMULASI DAN UJI STABILITAS SEDIAAN MINUMAN ALKALI LIDAH BUAYA (Aloe vera. L) SEBAGAI ANTIOKSIDAN Marini Marini; Imas Maesaroh; Haty Latifah Priatni
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.535

Abstract

Alkaline water is water with a higher pH level than normal drinking water, it has a pH between 7-9.5 and it also has antioxidant activity. Aloe vera (Aloe vera) contains nutrients, vitamins and minerals that can function as natural antioxidants, such as vitamins C, vitamins A, magnesium, and zinc. Fresh aloe vera is less acceptable and preferred because of its taste, so it is necessary to process A. vera into a more durable and acceptable product. This study aims at determining the best and acceptable A. vera alkaline drink formula through product stability testing, including organoleptic, pH measurement, microbiological test. Then, the selected formula is analysed for antioxidant activity using DPPH, while nutritional content testing including fat content, protein content, and carbohydrate content. The result of the stability test of alkaline A. vera drink with concentrations of F1 (10%), F2 (20%), and F3 (30%) after accelerated storage conditions at 5oC and 35oC organoleptically did not change, and ulfilled the requirements under the Minister of Health Regulation of the Food and Drug Administration number 13 of 2019, but the pH decreased because of oxidation reaction of phenolic compounds from A. vera gel which produced aloetic acid and chrysophanic acid. The hedonic test, a result of the selected formula was F3 (30%) had a strong antioxidant activity with an IC50 value of 9.952%, fat content 0.09%, protein content 0.16% and carbohydrate content 57.02%.

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