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Rusdiati Helmidanora
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ejournal.akfarsam@gmail.com
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+6285246812793
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ejournal.akfarsam@gmail.com
Editorial Address
Jl. Brig. Jend. Abdul Wahab Sjahranie No.226, Air Hitam, Samarinda, Kalimantan Timur, Indonesia
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Kota samarinda,
Kalimantan timur
INDONESIA
Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
ISSN : 2443115X     EISSN : 24771821     DOI : https://doi.org/10.51352/jim
Core Subject : Health, Science,
Jurnal Ilmiah Manuntung is a journal on pharmaceutical and health sciences published by Sekolah Tinggi Ilmu Kesehatan Samarinda which includes the study of pharmaceutical sciences, medicine, synthetic organic chemistry, organic chemistry of natural materials, biochemistry, analytical chemistry, physical chemistry, biology, microbiology, tissue culture, botany and animals related to pharmaceutical products, nursing, midwifery, health analysts, nutrition and public health.
Articles 326 Documents
FORMULASI SEDIAAN ANTIOKSIDAN FACIAL WASH EKSTRAK METANOL DAUN GANITRI (Elaeocarpus ganitrus Roxb.) DENGAN VARIASI SODIUM LAURIL SULFAT SEBAGAI SURFAKTAN Evi Marlina; Naelaz Zukhruf Wakhidatul Kiromah; Titi Pudji Rahayu
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 1 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i1.599

Abstract

Ganitri leaves (Elaeocarpus ganitrus Roxb.) contain flavonoid compounds that function as antioxidants. Antioxidants in cosmetics are used to prevent skin damage due to exposure to free radicals. Facial Wash is a cosmetic preparation to help remove dead skin cells, rejuvenate the skin, remove dirt, oil and provide moisture. This study aims to obtain a facial wash formula that has good characteristics and is effective as an antioxidant by varying the concentration of sodium lauryl sulfate, namely F1 (0.25%), F2 (0.5%) and F3 (1%) as surfactant. The results showed that variations in SLS concentration had a significant effect on the physical evaluation of the preparation with a p value of <0.05. Formula 3 (SLS 1%) provides the best facial wash characteristics with the results of the test parameters meeting the standards. The results of the antioxidant activity test showed that formula 3 had an IC50 value of 17.36 ppm which was categorized as very strong with ascorbic acid as a comparison of 10.70 ppm and a negative control of 54.11 ppm.
STUDI PENGELOLAAN OBAT DI PUSKESMAS BOJA 1 KABUPATEN KENDAL TAHUN 2020 Richa; Margareta Ayu Lestari; Lyla Aprilia; Niken Dyahariesti
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.609

Abstract

Drug management is an important aspect that affects operational costs in improving the quality of pharmaceutical services at the Puskesmas. The purpose of this study was to determine the efficiency of drug management at the stages of distribution, storage and use at the Boja 1 Public Health Center. This research was a non-experimental study with a descriptive approach. Data collection was taken retrospectively using reporting data for the 2020 period. Data processing was carried out by analyzing and comparing the suitability of the results with the standard indicators of Pudjaningsih (1996) and the Indonesian Ministry of Health (2011). The results of the research at the distribution stage show that the drug distribution system is appropriate. Based on the turn over ratio indicator, the result is 3.2 times, the drug availability indicator is 31.5 months, the percentage of expired drugs is 2% and the dead stock indicator is 32%. At the storage stage the results of the conformity percentage were 78%. At the use stage, the indicator for the average number of drug items was 3.69, the percentage for generic drugs was 62.06%, the percentage for prescribing antibiotics was 12.2% and the percentage for injection was 4.07%. Drug management at the stages of distribution, storage and use at the Boja 1 Health Center is not fully 100% in accordance with the indicator standards.
PENGARUH EKSTRAK DAUN EKOR NAGA (Rhaphidophora pinnata (L.f) Schott) TERHADAP KADAR MALONDIALDEHID DARAH PADA TIKUS DIABETES YANG INDUKSI ALOKSAN Fathnur Sani K; Havizur Rahman; Yuliawati Yuliawati; Agung Giri Samudra
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.623

Abstract

Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves is a traditional medicinal plant that contains secondary metabolites of alkaloids, flavonoids, saponins, and tannins, which have antioxidant effects. Uncontrolled diabetes mellitus will be one of the triggers for high free radicals in the body. This study aims to determine the effect of the effect of ekor naga leaves extract which has potentian as an antioxidant on malondialdehyde levels as a prooxidant marker in alloxan-induced diabetes mellitus rats. The reseaech method used a post test only control group design. The test animals used were 20 animals, each group of 5 test animals. Group 1: Positive Control (Glibenclamide 10 mg/Kg BW), Group 2: Negative Control (Na CMC 0,5%), Group 3: Ekor Naga Leaf Extract 250 mg/Kg BW, and Group 4: Ekor Naga Leaves Extract 500 mg/Kg BW. The data taken is the level of malondialdehyde in the blood. The results were analyzed using One-way ANOVA with a 95% confidence level. The results showed that the ethanolic extract of the ekor naga leaves had a role in reducing Malondialdehyde or lipid peroxide in the blood in diabetic rats where the best dose is 500 mg/Kg with malondialdehyde yield of 0,569 nmol/mL. Followed by a dose of 250 mg/Kg BW with malondialdehyde value of 2,144 nmol/mL.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN BODY LOTION EKSTRAK KOPI ROBUSTA (Coffea canephora) DENGAN METODE DPPH (2,2-difenil-1-pikrilhidrazil): English; Indonesia Repining Tiyas Sawiji; Elisabeth Oriana Jawa La; I Komang Tri Musthika
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.629

Abstract

The skin is the outermost part of the body and is very susceptible to exposure to free radicals. This can be prevented by using cosmetics that contain antioxidants. Coffee beans have the chemical compound chlorogenic acid which belongs to the phenolic group which is useful as an antioxidant. The purpose of this study was to formulate and test the antioxidant activity of Robusta coffee extract body lotion preparations.The method used is pure experiment and control class as a comparison. Analysis of physical quality data was carried out by means of descriptive analysis using tables based on the results of the average calculation of the physical quality test, antioxidant test using DPPH method, and statistical processing of hedonic test data using the One Way Anova test and continued with the Duncan test. The results showed that FII and FIII could be formulated into body lotion preparations and met the physical quality test requirements. The antioxidant test before storage obtained the IC50 value at FI of 47,61 ppm (AAI = 0,84); FII of 43,86 ppm (AAI = 0,91); and FIII of 34,07 ppm (AAI = 1,17) and after FI storage of 49,95 ppm (0,80); FII of 45,47 (AAI = 0,88); FIII of 36,11 ppm (AAI = 1,11). The results of the hedonic test showed that in the parameters of colour, aroma, texture, and comfort of use there were significant fifferences (<0,05), while the parameters of humidity and ease of rinsing alowed insignificant differences (>0,05). Based on the results obtained, Robusta coffee extract body lotion is able to ward off free radicals in the medium – strong category.
AKTIVITAS ANTIBAKTERI FRAKSI ETIL ASETAT DAUN JAMBU AIR (Syzygium aqueum) TERHADAP Shigella dysentriae Pupunk Fajriyani; Aulia Nur Rahmawati; Novena Yety Lindawati
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.630

Abstract

Shigella dysentriae is a genus of Shigella which has a high percentage of causing dysentery by 25%. The ethyl acetate fraction of guava leaves has potential as an antibacterial because the amount of compounds that provide antibacterial activity are more attracted in this solvent. The purpose of this study was to see the potential for inhibition of the ethyl acetate fraction of guava leaves (Syzygium aqueum) at each variation of its concentration against the bacterium Shigella dysentriae. The ethyl acetate fraction was obtained by liquid-liquid fractionation. The ethyl acetate fraction was tested in the zone of inhibition against Shigella dysentriae with various concentrations of 12.5%, 25%, 50%, and 100%, Ciprofloxacin positive control and 100% DMSO negative control. The data obtained were processed using One Way Anova with a 95% confidence level. The results of phytochemical screening of the ethyl acetate fraction of guava leaves showed positive for flavonoids, alkaloids, tannins, saponins, and steroids. Inhibition test of ethyl acetate fraction of guava leaves against bacteria Shigella dysentriae had the smallest inhibitory power at a concentration of 12.5%, the inhibitory power was 6.3 mm; 25% concentration of 15.3 mm; 50% concentration of 16.7 mm; and the concentration of 100% the largest inhibitory power was 18.4%. The results of the antibacterial inhibition of the ethyl acetate fraction of guava leaves had a significant difference in each concentration with a significance value (p <0.05).
PENGARUH VARIASI KONSENTRASI NaOH TERHADAP SIFAT FISIK SABUN PADAT EKSTRAK UBI JALAR UNGU (Ipomoea batatas Lam) Dewi Rashati; Dewi Riskha Nurmalasari; Vira Ananda Putri
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.635

Abstract

Soap is a cleanser made by reacting chemically between a sodium base and a fatty acid. NaOH is varied because it is the main ingredient in the saponification process. This study aims to determine the effect of variations in NaOH concentration on the physical properties of solid soap preparations of purple sweet potato extract (Ipomoea batatas Lam.). The research method used is a pre-experimental one group post test design. The carrier material used in this study was NaOH with different concentrations of F1 (5%), F2 (8.5%), F3 (12%). The active ingredient used in this study was purple sweet potato extract as an antioxidant. Evaluation includes organoleptic (texture, color, smell), pH, moisture content, and foam height. The results showed that changes in NaOH concentration had an effect on the organoleptic physical properties of texture, pH, water content, and foam height of solid soap preparations and did not affect the organoleptic color and smell. The formula with 8.5% NaOH concentration gave the best physical characteristics in terms of organoleptic, namely smooth texture, light brown color, strong bubble gum smell, pH 9.9, water content 0.5%, high foam in 9 cm aquadest.
PENGUKURAN PERSEPSI TENAGA TEKNIS KEFARMASIAN DI KOTA DAN KABUPATEN SEMARANG TERHADAP APOTEK ONLINE Fef Rukminingsih; Azifatul Ula; Dian Safitri
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.636

Abstract

The development of online pharmacies in Indonesia will have an impact on the existence and role of Pharmaceutical Technicians. The number of pharmacies in Semarang City and Regency has reached almost 500 units. The number of Pharmaceutical Technicians who have practice permits in Semarang City is 477 people and in Semarang Regency is 115 people. Objective: This study aims to measure the perception of Pharmaceutical Technicians in Semarang City and Regency towards online pharmacies. Method: This research is a descriptive observational study using a cross sectional study design with using purposive sampling technique. The research data was obtained through a questionnaire in the form of a Likert scale which was distributed via google form in the Whatsapp group of Persatuan Ahli Farmasi Indonesia of Semarang City and Regency. Perceptions that are measured are drug guarantees, prices and consumer services. Pharmaceutical Technicians is said to have a positive perception of online pharmacies if the average score of the three parameters is in the range of 802.5 – 1284. Results: Respondents involved in this study were 321 respondents. Female respondents were 288 respondents (89.72%), 270 respondents (84.11%) aged less than 36 years and 177 respondents (55.14%) had Diploma III Pharmacy education. The drug guarantee parameter got a score of 1098, the drug price parameter got a score of 904 and the consumer service parameter got a score of 1035.5. The average score for the three parameters is 1012.5. Conclusion: Pharmaceutical Technicians in Semarang City and Regency have a positive perception toward online pharmacies.
PENGARUH PRAPERLAKUAN OVEN TERHADAP AKTIVITAS ANTIOKSIDAN MINYAK KEMIRI (Aleurites moluccana (L.) Willd) DENGAN METODE DPPH (1,1-Diphenyl-2-picrylhydrazyl) Lenny Novita; Aldi Budi Riyanta; Akhmad Aniq Barlian
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.637

Abstract

Candlenut (Aleurites moluccana (L.) Willd) is a plant that is efficacious as an alternative to traditional medicine and contains antioxidant compounds that can donate one or more electrons to free radicals, so that free radical reactions can be inhibited. In addition, the candlenut plant has a relatively hig oil content in candlenut seeds, which is around 55-66%. This study aims to determine the effect of oven time at 40℃ on the yield of candlenut oil and antioxidant activity. The method used is that the candlenut seeds are axtracted using a press machine, previously the candlenut seeds have been pretreated in the oven time variations for 1, 3, and 5 minutes at 40℃. The results showed that the highest yield was at a temperature of 40 for 3 minutes, which was to get results with a yield value of 55,83%. In the concentration and probit log data, it was stated that sample 3 with a time of 5 minutes got the best maximum IC50 value of 109,647 µg/mL, with the IC50 value, candlenut oil was classified as an active antioxidant. Based on these results it can be concluded that the use of oven time pretreatment affected the yield and antioxidant activity.
UJI STABILITAS DAN UJI HEDONIK MASKER GEL PEEL-OFF EKSTRAK DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) DENGAN VARIAN KONSENTRASI POLIVINIL ALKOHOL (PVA) SEBAGAI FILMING AGENT Tri Puji Lestari; Anisa Riana Putri; Ida Kristianingsih; Evi kurniawati; Fita Sari
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.639

Abstract

Research on the Formulation Physical Stability Test and hedonic test of the peel-off gel mask of binahong Leaf Extract has been conducted. This study aims to determine the best formula of the binahong Leaf Extract peel-off gel mask preparation with PVA as a filming agent. The steps of the procedure in this research include plant determination, sample preparation, making binahong leaves simplicia, making binahong leaves extract, formulation of peel off gel mask evaluation of physical properties, stability test, irritation test and hedonic test. Formulation of binahong Leaf Extract peel-off gel mask were carried out in three formulas with various variations of PVA concentrations of 5%, 5,5%, and 6%. The results of the physical properties test shows that peel-off extract masks of binahong leaves with different concentration variations differ in organoleptic, ph test, and drying time test a statistical data analysis. Based on the results of the stability test using the cycling test method with temperature ± 4̊ C and ± 40̊ C over the course of six cycles. he most stable results of existing tests are F2 and F3 showed no significant differences in each evaluation. Test irritation suggests that the gel peel-off mask was not irritating. From the hedonic test results, panelists prefer F3 compared to other formulas.
UJI KARAKTERISTIK FISIK DAN HEDONIK DARI ANTIAGING SLEEPING MASK DENGAN EKSTRAK KULIT BUAH DELIMA MERAH Fransisca Dita Mayangsari; Djati Wulan Kusumo; Zurotul Muarifah
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.640

Abstract

ABSTRACT Red pomegranate peel extract (RPPE) contains ellagitannin. This compound has an antioxidant effect. Therefore,this extract has good potential as an active ingredient in anti-aging cosmetics. However, applying the extract directly to the skin is inconvenient. So in this study RPPE was formulated into a sleeping mask. This study aims to analyze the effect of variations in the concentration of RPPE in sleeping masks on physical characteristics and the level of preference/hedonic. RPPE concentration observed was 2.5% (F1) ; 5% (F2) ; 7.5% (F3). Characteristic tests include organoleptic, pH value, visual homogeneity, consistency and viscosity. Parameters analyzed in the hedonic test include texture, color, and aroma. The organoleptic and homogeneity were analyzed descriptively. The test data for pH and viscosity were analyzed statistically using the One Way ANOVA method. The results of the hedonic test were analyzed statistically using the univariate method. Based on the results of the organoleptic test, it is known that F1 have a light brown color, F2 is brown, and F3 is dark brown. The third formula is visually homogeneous. The higher the concentration of RPPE, the lower the pH value and viscosity of the preparation. Increasing the concentration of RPPE reduce consistency. This study concluded that the concentration of RPPE affects the physical properties of the aspects of color, consistency, pH, and viscosity. The concentration of RPPE also affects the level of preference of the panelists. Most of the panelists prefer the color and texture of the sleeping mask that contains low concentration of RPPE (2.5%). Keywords : Physical Characteristics ; Hedonic; Sleeping Mask ; Red Pomegranate Peel Extract