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INDONESIA
MEDICA (International Medical Scientific Journal)
Published by Borneo Scientific Publishing
ISSN : 26226596     EISSN : 2622660X     DOI : https://doi.org/10.53770/medica
Core Subject : Health, Science,
Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary
MEDICA (International Medical Scientific Journal), with registered number ISSN 2622-6596 (Print), 2622-660X (Online) is an Open Access and peer-reviewed journal presenting timely research on all aspects of health that other media have not published. Managed by the Borneo Scientific Publishing, published by Borneo Scientific Publishing. MEDICA (International Medical Scientific Journal) will publish journals three times yearly: January, May, and October. Manuscripts are published as original articles, review articles, and case reports. The Journal invites public health concerned with any of these areas to submit research on topics including, but not limited to Health promotion & disease prevention in all stages of human life, Medical laboratory, Nursing, Environmental Health, Epidemiology and biostatistics. Health policy and administration, Public health nutrition, Occupational health and safety, Health Promotion, Reproductive health, maternal and child health, and other related articles in public health.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 40 Documents
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Utilization of Red Dragon Fruit (Hylocereus polyrhizus) as an Alternative Dye for Threadworm Eggs (Ascaris lumbricoides) Erfiana, Desti; Nurhayati, Etiek; Ratnawaty, Gervacia Jenny
MEDICA (International Medical Scientific Journal) Vol. 7 No. 1 (2025): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v7i1.483

Abstract

The red dragon fruit (Hylocereus polyrhizus) contains a pigment called anthocyanin, which gives it its red color and has the potential to be used as a natural dye. In laboratory microscopic preparations, eosin is used as a standard dye. Natural dyes have the advantage of not causing negative effects like cancer or environmental damage. This study aimed to examine the potential of red dragon fruit (Hylocereus polyrhizus) as an alternative dye for the examination of Ascaris lumbricoides eggs. The study design used was static group comparison, with local red dragon fruit samples from Pontianak Tenggara District. Laboratory examination methods involved direct microscopic observation using a 2% eosin control. In this study, the juice from both the skin and flesh of the red dragon fruit was extracted and prepared in solutions of 80%, 90%, and 100% concentrations with four replications. The results showed that the skin of the red dragon fruit at concentrations of 80%, 90%, and 100% was not suitable for coloring the microscopic preparation for observing worm eggs. However, the juice from the flesh of the red dragon fruit at concentrations of 80%, 90%, and 100% could color the microscopic preparations, and the Ascaris lumbricoides eggs could be identified. At the 80% concentration of red dragon fruit flesh, the average score was 2, indicating low contrast background, weak color absorption by the eggs, and unclear egg details. At 90% and 100% concentrations, the average score was 3, indicating a clear contrast background, good color absorption by the eggs, and clear egg detail, similar to eosin 2% staining. This study concludes that the skin of red dragon fruit cannot be used for staining microscopic preparations, while the flesh of red dragon fruit can be used for staining Ascaris lumbricoides eggs, with optimal concentrations of 90% and 100%.
The Relationship Between Premature Rupture of Membranes (PROM) and Leukocyte Levels in Newborns Grovindo, Grovindo; Sutriswanto, Sutriswanto; Nuswantoro, Ari; Cholsakhon, Panyada
MEDICA (International Medical Scientific Journal) Vol. 7 No. 1 (2025): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v7i1.484

Abstract

Premature Rupture of Membranes (PROM) remains a global concern in obstetrics due to its potential to cause complications such as infections that increase maternal and neonatal morbidity and mortality. PROM occurs in approximately 10–15% of pregnancies worldwide and 8–10% in Indonesia, often before 37 weeks of gestation, contributing significantly to preterm births and neonatal deaths. Risk factors for PROM include maternal age, parity, infection, and other pregnancy-related conditions. Infection resulting from PROM can be identified through leukocyte count in newborns, with leukocytosis indicating the presence of infection. This study aimed to examine the relationship between PROM and leukocyte levels in newborns at RSUD Drs. Jacobus Luna, M.Si, Bengkayang Regency, using a descriptive-analytic design with a cross-sectional approach and total sampling of 88 respondents. Results showed that among 36 newborns with elevated leukocyte levels, 28 cases (77.8%) were born from PROM pregnancies, whereas only 8 cases (22.2%) were non-PROM. Among 52 cases with normal leukocyte levels, only 11 newborns (21.2%) had PROM, while 41 (78.8%) did not. These findings indicate that newborns from PROM pregnancies tend to have higher leukocyte counts. Statistical analysis using Chi-square showed a significant relationship between PROM and leukocyte levels, with a p-value of 0.000 (< 0.05). In conclusion, PROM is a notable risk factor for increased leukocyte counts in neonates, underscoring the importance of early detection and management of PROM to reduce the risk of neonatal infection and its associated complications.
Factors Associated with Hyperbilirubinemia in Newborns at Tanjungpura University Hospital, Pontianak Panjaitan, Anggita Ria; Tumpuk, Sri; Sari, Emilda; Yunus, Mohd
MEDICA (International Medical Scientific Journal) Vol. 7 No. 1 (2025): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v7i1.485

Abstract

In Indonesia, neonatal death is often caused by low birth weight, asphyxia, birth trauma, hyperbilirubinemia, infections, and congenital abnormalities. Hyperbilirubinemia in neonates generally occurs due to the immaturity of organs in processing bilirubin, with phototherapy as the primary treatment. Recent studies have shown an increase in cases of hyperbilirubinemia at Tanjungpura University Hospital in Pontianak, highlighting the need for further research on the factors influencing this condition. The aim of this study is to analyze the factors associated with hyperbilirubinemia in newborns at Tanjungpura University Hospital in Pontianak. This research used an analytical observational design with a cross-sectional approach. The sample consisted of 67 respondents selected through total sampling. The distribution of maternal gestational age showed 49.3% preterm and 50.7% term. Of the respondents, 50.7% had ABO incompatibility, while 49.3% did not. A total of 58.2% of the newborns had normal birth weight, while 41.8% did not. Regarding delivery type, 67.5% were delivered by cesarean section (C-section), and 34.3% by normal delivery. The results of the Chi-Square Continuity Correction test showed p=0.038 for gestational age, p=0.018 for ABO incompatibility, p=0.001 for birth weight, and p=0.202 for delivery type. In conclusion, there is a significant relationship between gestational age, ABO incompatibility, and birth weight with the occurrence of hyperbilirubinemia, but no significant relationship with the type of delivery.
The Relationship Between NS1 Examination and the Examination of Hemoglobin, Hematocrit, Leukocytes, Platelets, and Erythrocytes in Dengue Fever Patients in The Pediatric Ward Ratulangi, Agus Dimas; Djohan, Herlinda; Kamilla, Laila
MEDICA (International Medical Scientific Journal) Vol. 7 No. 1 (2025): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v7i1.486

Abstract

The NS1 antigen test is developed to detect dengue virus infection during the acute phase, a stage marked by various hematological abnormalities. An increase in hemoglobin levels greater than 20% can support the diagnosis of Dengue Hemorrhagic Fever (DHF), often caused by hemoconcentration due to plasma leakage, which also raises erythrocyte levels in the bloodstream. This study aimed to examine the relationship between NS1 test results and hemoglobin, hematocrit, leukocyte, platelet, and erythrocyte levels in pediatric DHF patients at Dr. Soedarso Regional Hospital. Using a cross-sectional design with total sampling, 203 samples were collected from suspected pediatric DHF patients between May and July 2023. Data included NS1 results and hematology parameters. The analysis showed a significant association between positive NS1 results and hemoglobin levels (p = 0.025) as well as platelet counts (p = 0.035), but no significant relationship with hematocrit (p = 0.872), leukocytes (p = 0.269), or erythrocytes (p = 0.060). In conclusion, NS1 positivity is significantly associated with hemoglobin levels and platelet count, but not with hematocrit, leukocytes, or erythrocytes in pediatric DHF patients.
The Antibacterial Effectiveness of Moringa Oleifera Leaves Extract Against the Growth of Escherichia coli Using the Diffusion Method Annisa, Liza Harum Nur; Triana, Linda; Sari, Emilda; Nuswantoro, Ari
MEDICA (International Medical Scientific Journal) Vol. 6 No. 3 (2024): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i3.487

Abstract

Moringa oleifera leaves a common herbal plant found in tropical regions and naturalized in Indonesia, are known to be rich in bioactive compounds such as flavonoids, tannins, terpenoids, alkaloids, and saponins. These compounds have potential medicinal properties, including antibacterial activity. This study aims to examine the antibacterial effectiveness of moringa leaf extract against the growth of Escherichia coli using the diffusion method. This descriptive-analytical research employed a purposive sampling technique with varying concentrations of moringa leaf extract: 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, and 100%. Each concentration was tested in triplicate, resulting in a total of 30 samples. The antibacterial effectiveness test was conducted using the agar diffusion method with blank paper disks. The results showed that no inhibition zones were formed at concentrations of 10% and 20%. Inhibition zones began to appear at 30% concentration (7.3 mm), increasing with higher concentrations: 40% (9 mm), 50% (10.3 mm), 60% (11.3 mm), 70% (16.6 mm), 80% (23.3 mm), 90% (28.3 mm), and reaching 34.6 mm at 100% concentration. Based on the antibacterial activity category, 10% and 20% showed no activity, 30% and 40% were categorized as weak, 50% and 60% as moderate, 70% as strong, and 80%, 90%, and 100% as very strong. It can be concluded that an 80% concentration of moringa leaf extract is the most effective in inhibiting the growth of Escherichia coli.
Phytochemical Identification and Antioxidant Activity Test of Acetone Extract of Celery Leaves (Apium graveolens L.) Using the DPPH (2,2-diphenyl-1-picrylhydrazyl) Method Auliannisa, Riska; Jenny, Gervacia; Djohan, Herlinda
MEDICA (International Medical Scientific Journal) Vol. 6 No. 3 (2024): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i3.488

Abstract

Free radicals are formed in the body through oxidation processes and cell combustion during breathing, metabolism, excessive physical activity, as well as exposure to external pollution. Antioxidants play an important role in protecting the body from oxidative damage. Celery leaves (Apium graveolens L.), which are rich in flavonoid compounds, have the potential to be a natural source of antioxidants. This study aims to identify the secondary metabolite content and measure the antioxidant activity of acetone extract of celery leaves based on IC50 values using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The study uses a quasi-experimental design with purposive sampling techniques. The antioxidant activity of acetone extract of celery leaves at concentrations of 30 ppm, 50 ppm, 70 ppm, and 90 ppm was tested using a UV-VIS spectrophotometer at a wavelength of 516 nm. The results showed the presence of secondary metabolite compounds such as alkaloids, flavonoids, phenols, triterpenoids, saponins, and tannins in the acetone extract of celery leaves. The IC50 value of the acetone extract of celery leaves was 115.09490 ppm, indicating moderate antioxidant activity (IC50 value between 100–250 ppm). These findings conclude that acetone extract of celery leaves has potential to be used as a natural antioxidant source.
Overview of the Effect of Storage Duration of Sweet Orange Juice (Citrus sinensis L.) on Bacterial Count Using the MPN (Most Probable Number) Method Hariyanis, Hariyanis; Sutriswanto, Sutriswanto; Supriyanto, Supriyanto
MEDICA (International Medical Scientific Journal) Vol. 6 No. 3 (2024): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i3.489

Abstract

Sweet oranges (Citrus sinensis L.) are rich in nutrients that support overall health, particularly brain function. They contain essential components such as vitamin C, folic acid, phytochemical fibers, and various minerals including calcium, potassium, and magnesium. These nutrients may contribute to the prevention of conditions such as cancer, kidney stones, digestive disorders, high cholesterol, and hypertension. This study aimed to determine the bacterial count in sweet orange juice using the Indonesian National Standard (SNI) No. 3719-20 method at room temperature. The research was conducted as a descriptive observational study. Sweet oranges were purchased from the Amifruts Shop in Pontianak. The juice was extracted and diluted with water at a 1:1 ratio, then divided into five samples and stored at room temperature for 2, 3, 4, 5, and 6 hours, respectively. Samples were cultured on LB media and incubated at 37°C for 24 hours to observe bacterial growth, indicated by changes in the medium. Based on the Most Probable Number (MPN) method, two samples tested positive for coliform bacteria, with an estimated bacterial count of approximately 25. It can be concluded that there was some Coliform bacterial contamination at specific times.
Description of Total Protein Levels in Pregnant Women at the Tambelan Sampit Health Center, Pontianak Sunti, Matius; Sutriswanto, Sutriswanto; Sari, Emilda
MEDICA (International Medical Scientific Journal) Vol. 6 No. 3 (2024): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i3.490

Abstract

Pregnancy is a critical period characterized by the growth and development of the fetus, during which the nutritional needs of the mother, including total protein intake, increase significantly. Total protein in the blood comprises albumin, globulin, and small amounts of other proteins, all essential for maternal and fetal health. This descriptive-analytic study aimed to determine the total protein levels in pregnant women attending the Tambelan Sampit Health Center. The study involved 30 pregnant women, including 9 in the first trimester, 10 in the second trimester, and 11 in the third trimester. Data were collected without generalization analysis to describe the condition of the study population. The highest total protein levels were observed in the first trimester (8.2 g/dL), followed by the third trimester (7.3 g/dL), and the second trimester (7.1 g/dL). In the first trimester, 55.6% of participants had normal protein levels, and 44.4% had abnormal levels. In the second trimester, 80% had normal levels, and 20% had abnormal levels. In the third trimester, 81.9% showed normal levels, and 18.1% had abnormal levels. It can be concluded that most of the pregnant women in this study had total protein levels within the normal range across all trimesters. Further research is recommended to conduct a more in-depth investigation of total protein levels during pregnancy.
Analysis of the Use of Virgin Coconut Oil as an Alternative Soaking Agent on the Quality of Ctenocephalides felis Preparations Daratista, Ayu; Ihsan, Bagus Muhammad; Salim, Maulidiyah
MEDICA (International Medical Scientific Journal) Vol. 6 No. 3 (2024): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i3.491

Abstract

Preservation preparations are a technique for preserving parasite specimens, including Ctenocephalides felis (cat flea), involving several stages: fixation with 10% KOH, dehydration using graded alcohols (30%, 50%, 70%, 96%, absolute), clearing, and mounting. The clearing process aims to clarify the morphological structure of the parasite. This study aims to investigate the function of virgin coconut oil (VCO) as an alternative to xylene in the clearing stage, in terms of the clarity and quality of the preparation. The research design used is a quasi-experimental approach with purposive sampling technique. The research population consists of fleas, and the sample included 16 cat fleas (Ctenocephalides felis) that underwent the clearing process using virgin coconut oil (VCO). The results of the study showed that out of the 16 preparations, 9 still had residual chitin layers, while 7 did not. Based on the quality of the preparation, there were 7 preparations with good quality (44%), 6 moderately good (38%), and 3 poor (18%). This study concluded that virgin coconut oil is capable of clarifying Ctenocephalides felis preservation preparations and can serve as an alternative to xylene in the clearing process, with the preparation quality being sufficient for microscopic morphological observation of fleas.
The Relationship Between Hepatitis B Surface Antibody Levels and the Levels of Serum Glutamic Pyruvic Transaminase, Serum Glutamic Oxaloacetic Transaminase, and Total Bilirubin Dewi, Ni Putu Ditya Prabandari; Bekti, Heri Setiyo; Purna, I Nyoman
MEDICA (International Medical Scientific Journal) Vol. 6 No. 2 (2024): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v6i2.492

Abstract

Hepatitis B virus is a disease that can impair other functions of the liver. This study aims to determine the relationship between Hepatitis B antibody levels and the levels of SGOT (Serum Glutamic Oxaloacetic Transaminase), SGPT (Serum Glutamic Pyruvic Transaminase), and bilirubin. A quantitative analytic study with a cross-sectional approach was conducted. Data collection involved primary data in the form of hepatitis B serum samples and secondary data including SGOT levels, SGPT levels, bilirubin levels, age, gender, and medical history. The results showed a significant and inverse relationship between Hepatitis B antibody levels and SGOT levels, with a Sig. (2-tailed) value of 0.029 (<0.05) and a negative correlation coefficient of -0.627. Similarly, there was a significant and inverse relationship between Hepatitis B antibody levels and SGPT levels, with a Sig. (2-tailed) value of 0.003 (<0.05) and a negative correlation coefficient of -0.616. However, there was no significant relationship between Hepatitis B antibody levels and bilirubin levels, as indicated by a Sig. (2-tailed) value of 0.809 (>0.05), although the correlation was positive (correlation coefficient = 0.078). In conclusion, Hepatitis B antibody levels show a significant negative correlation with SGOT and SGPT levels, while the correlation with bilirubin levels is positive but not statistically significant.

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