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INDONESIA
Berkala Ilmu Kesehatan Kulit dan Kelamin
Published by Universitas Airlangga
ISSN : 19784279     EISSN : 25494082     DOI : 10.20473
Core Subject : Health, Science,
Immunology & microbiology Public Health
Arjuna Subject : -
Articles 505 Documents
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The Burden of Leprosy Reaction in the Post-Elimination Era: A Study from Gresik City, Indonesia Kinanti, Hapsari; Kurniati; Faidati, Wind
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.41-46

Abstract

Background: The attention of leprosy management has shifted to reduce the burden of leprosy complications, including leprosy reactions. Leprosy reaction is the predominant cause of nerve impairment that leads to disability and lowers the quality of life of the affected. Purpose: The aim of this study was to provide primary data about leprosy reaction epidemiology, risk factor, and outcomes in the post-elimination era.  Methods: A cross-sectional study was held in a general hospital in Gresik City, Indonesia, to give clinical demography, risk factors, and outcomes of leprosy reaction. Result: New leprosy reaction cases remain detected each year. There were 57 (58.8%) out of 97 leprosy patients who had a reactional episode. The incidence of leprosy reactions has been increasing in the last three years. The multibacillary (MB) group and type 2 reactions dominated leprosy reactions, which mostly occurred in the young adult population. Some of the leprosy reaction patients had developed a complication due to prolonged steroid usage. Conclusion: Leprosy cases in a young population with a high risk of developing reaction episodes need collaboration in the management to prevent deformity in youth.
Impact of Scabies on Sleep Quality Azzahra, Fatimah; Manuputty, Amanda Gracia; Bandjar, Fitri Kadarsih; Silalahi, Parningotan Yosi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.193-198

Abstract

Background: Scabies is an infectious skin condition that occurs due to an infestation of the small parasitic mite known as Sarcoptes scabiei var. hominis. It causes symptoms of itching, which usually worsen during the night and can interfere with sleep. Purpose: The aim of the study was to examine how the incidence of scabies relates to the sleep quality of students at Al Anshor Islamic Boarding School in 2022. Methods: In this study, a quantitative approach was used with a cross-sectional research design. Primary data was collected through the diagnosis of scabies and the use of the Pittsburgh Sleep Quality Index (PSQI) questionnaire to measure sleep quality. Bivariate analysis was conducted using the chi-square test for data analysis. The research sample was obtained through the stratified random sampling method. Results: According to the findings, out of 42 participants, 26 students (61.9%) had scabies, with 11 males and 15 females affected. Most of the scabies cases were found in 17-year-old students. The study also found that all scabies sufferers had poor quality sleep. Statistical analysis revealed a significant association between the incidence of scabies and sleep quality, with a p-value of 0.000 and a 95% confidence interval. Conclusion: In conclusion, the study suggests that there is a link between the occurrence of scabies and sleep quality. Therefore, it is important to raise awareness about personal hygiene practices to reduce the spread of scabies.
Research Trend of Studies Regarding the Change and Treatment of the Skin on Pregnant Women in the Last Decade: A Systematic Review and Bibliometric Analysis Nauli, Agnes; Dalimunthe, Dina Arwina
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.203-213

Abstract

Background: The number of publications related to the change and treatment of the skin in pregnant women in the last decade has significantly grown. To date, however, a study offering comprehensive information related to the change and treatment of the skin in pregnant women has not been conducted or found in an electronic journal or proceeding. The purpose of this study is to present a bibliographic and bibliometric review of the numerous documents studying the skin of pregnant women. Methods: A systematic review involving bibliometric analysis with quantitative method was performed to carry out this studywhich 198 eligible documents from the Scopus database published in the period of 2013–2022 were used as research materials. Result: Results revealed that the publication and development of studies related to the change and treatment of the skin in pregnant women slightly soared from 2013 until 2022. Meanwhile, the citation development of he studies regarding the change and treatment of the skin in pregnant women tended to moderately decrease between 2013 and 2022. Additionally, influential documents, authors, countries, affiliations, and sources contributed to the development of studies related to the change and treatment of the skin in pregnant women. Discussion: In particular, this study informs us that the publication and development of studies related to the change and treatment of the skin in pregnant women slightly soared from 2013 until 2022. Most pregnant women undergo a skin change. This study implies that women must treat a skin change when they are pregnant.
Generalized Pustular Psoriasis in Childhood: A Rare Case Asnawi, Vella; Maulida, Mimi; Earlia, Nanda; Hidayati, Arie; Ismida, Fitri Dewi; Liana, Mahda Rizki; Maghfirah, Karamina; Bulqiah, Mikyal
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.231-236

Abstract

Background: Generalized pustular psoriasis (GPP) rarely occurs under 10 years of age. GPP is typically characterized by an eruption of generalized pustules accompanied by systemic symptoms such as fever for several days, malaise, and anorexia. Pustules are sterile, with a size of 2-3 mm, and spread over the trunk and extremities. This disease can be life-threatening; therefore, optimal therapy is required. Purpose: to report a rare case of GPP in childhood. Case: A 4-year-old girl with complaints of widespread red patches that spread to her neck, back, and hands, with red patches turning into streaks that are partially pus-filled and itchy. In almost all parts of the body, skin abnormalities were seen in the form of generalized erythematous plaques, well-defined borders, multiple pustules on the edges, and some plaques covered by thick scales and crusts. In the calculation of body surface area (BSA), the result is 44%, and in the calculation of generalized pustular psoriasis area and severity index (GPPASI), the result is 21.30. The patient was treated with combination topical therapy of 3% salicylic acid, desoximethasone cream 0.25%, momethasone cream 0.1% vaseline albume as emollients, and coal tar. Significant improvement was seen after 1 month of therapy. Discussion: GPP in children is a rare case. GPP is idiopathic and can be life-threatening. Until now, there has been no standard therapy that is considered the most effective and safe for children. Topical therapy may be an option.
Profile of Mild Acne Vulgaris Patients at Tertiary Hospital at Surabaya, Indonesia Arifin Saiboo, Alvian; Muhammad Yulianto Listiawan; Sari, Maylita; Indramaya, Diah Mira; Murtiastutik, Dwi; Damayanti; Anggaraeni, Sylvia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.26-30

Abstract

Background: One of the most prevalent skin conditions worldwide is acne vulgaris (AV). Even mild forms of AV could have an adverse impact on psychological wellbeing. Purpose: To explore the profile of mild AV patients in a tertiary care facility in Surabaya, Indonesia. Method: This was a descriptive study conducted for eight weeks. Data regarding the patient's identity, history, skin type, and complaints related to AV or other complaints that arose were noted on the sample's medical record and collected for analysis. The Lehmann classification was used to assess the AV degree. Result: A total of 34 patients were included. Gender equality was similar in our study, and late adolescence (17-25 years) is the most dominant age group (73.5%). Genetics plays the biggest precipitating factor (73.5%), followed by stress (70.6%). Most patients had an oily skin type (91.2%) with Fitzpatrick's phototype 4 (85.3%). Comedone is the most prevalent lesion in our study (median = 10, range = 4-20). Conclusion: Most patients with mild AV had an oily skin type, and late adolescent is most dominant age group.
Diagnosis and Management of Hair Loss in Pediatric Fitriani, Fitriani; Antonius, Cayadi Sidarta; Kartowigno, Soenarto; Diba, Sarah; Argentina, Fifa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 2 (2024): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.2.2024.142-148

Abstract

Background: Hair loss can occur in pediatric and adult populations and may have different patterns. The causes of hair loss in pediatric patients include tinea capitis, alopecia areata, telogen effluvium, traction alopecia, anagen effluvium, androgenetic alopecia, loose anagen syndrome, short anagen syndrome, congenital aplasia cutis, congenital triangular alopecia, atrichia congenita, congenital hypotrichosis, and transient neonatal hair loss.Purpose: to understand etiologies of hair loss in pediatrics, and to determine the appropriate examinations for diagnosing and managing hair loss in children.Review: Hair loss in children can be categorized as congenital or acquired. Congenital hair loss is classified based on distribution, while acquired hair loss is classified as either scarring or non-scarring. Hair loss complications in children can be irreversible. The diagnosis of hair loss in pediatric patients includes anamnesis, physical examination, and supporting examinations. The supporting examinations used for diagnosis include fungal cultures, hair pull tests, hair tug tests, light microscopy, and trichoscopy. Conclusion: There are numerous causes of hair loss in pediatric patients that need to be identified before appropriate management can be implemented. The management of hair loss requires a holistic approach, including psychosocial support. Correct diagnosis and treatment of pediatric hair loss can prevent a decrease in the patient's quality of life.
The Association of Keloid Site with its Histopathological Features: an Analytical Observational Study Wibisono Nugraha; Muhammad Eko Irawanto; Moerbono Mochtar; Nur Rachmat Mulianto; Novan Adi Setyawan; Nugrohoaji Dharmawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.47-52

Abstract

Background: Keloid is a growth of fibrous tissue in the wound tissue of susceptible individuals. This tissue extends beyond the boundaries of the previous wound. The site of keloids commonly appears on a high-tension area, such as the chest, shoulders, and neck. Histopathologically keloids show thickened the epidermis and the vascularization and infiltration of inflammatory cells in the dermis. Purpose: This study aims to determine the relationship between the site of keloids and the histopathological appearance of keloids. Methods: An analytical observational study was conducted on keloid patients visiting the Dermatovenereology outpatient clinic of Dr.Moewardi Hospital. The sample collection used consecutive sampling techniques Result: The majority of keloid patients are >30 years old (46.4%). Most patients with keloids were female (53.6%). Keloids were mostly found on the chest (25.0%). Tounge-like appearance of the epidermis at the edges of the lesions was mostly on the shoulders and chest (33.3% each, p=0.048); flattened appearance was found on the middle epidermis of the lesions, which were mostly on the ears, shoulders, and upper extremities (22.7% each, p=0.011). Increased vascularity was found in the dermis at the edges of the lesions, especially in the ear and chest areas (31.3% each, p=0.046). Moderate-severe inflammatory infiltrates in the dermis at the edges of the lesions were commonly found on the chest (p=0.04). Conclusion: There is a significant relationship between the site of the lesion and the histopathological appearance of the keloid in epidermal as well as dermal layers.
Concordance Test Between Dermoscopic and Histopathological Parameteres in Basal Cell Carcinoma Hartanto, Felix; Kusumaputra, Bagus Haryo; Sari, Maylita; Citrashanty, Irmadita; Mappamasing, Hasnikmah; Astari, Linda; Sandhika, Willy; Hidayati, Afif Nurul; Prakoeswa, Cita Rosita Sigit; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.6-11

Abstract

Background: Basal cell carcinoma (BCC) is the most common skin cancer and can cause local tissue damage. BCC can occur in all populations, regardless of skin color. Dermoscopy has compatibility with histopathology in determining the benign or malignant nature of a lesion. Dermoscopy can improve the diagnostic accuracy of BCC by >90%, with 7 parameters that can be found: arborizing vessels, blue-gray ovoid nests, blue-gray dots/globules, maple leaf-like areas, spoke-wheel areas, ulceration, and hiny white areas. Purpose: To assess the compatibility of each dermoscopy parameter with its corresponding histopathological parameters. Methods: Observational analytic study with a cross-sectional approach was performed. Dermoscopy parameters were obtained by reassessing all photographs, while histopathological parameters were obtained from pre-existing slide reviews. Cohen's Kappa test was performed to analyze both variables. Result: A Total of 26 samples met the inclusion criteria. Most BCCs were found in female sex (65.4%), age >50 years (80.8%), and facial location (88.5%). Cohen's Kappa test was significant in 2 out of 7 dermoscopy parameters: "blue-gray ovoid nests" (p = 0.0019; r = 0.458) and "spoke wheel areas" (p = 0.037; r = 0.371). The "shiny white areas” parameter could not be analyzed because there was no negative variation in the examination. The possibility of false positives and negatives could not be ruled out.  Conclusion: Significance between the two variables is found in 28.6% of the 7 parameters analyzed...
Epigenetic Alterations in Keloid a Possible Method to Find Novel Agents for Keloid Treatment Budiyanto, Arief Budiyanto; Wirohadidjojo, Yohanes Widodo
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.60-67

Abstract

Background: Keloids are dermal fibro-proliferative disorders due to prolonged wound healing processes with excessive collagen depositions, which produce symptoms of itching and pain, cosmetic disfigurement, and limitation of joint motion. Standard treatment for keloid has not been accepted yet. It may be due to the complexities and poorly understood keloid development that are driven by various factors from systemic to local, genetic to epigenetic. Since genetic factors are difficult to manipulate, an approach to epigenetic factors may be hopeful. Purpose: To review various related reports on epigenetic factors such as DNA methylations, histone modifications, and micro-RNAs, which have significant roles in keloid development and can be used as targets for novel agents in keloid treatment. Review: Various genes in keloid fibroblasts (KFs) are repressed by DNA methylation, and one of them can inhibit the regulation of TGF-β1/Smad signaling, whereas another gene may influence anti-fibrotic events. Either inhibitor of methyl-transferase, inhibitor of histone-acetyltransferase, or histone-deacetylase can reduce TGF-β1/Smad signaling in KFs. Abnormal expressions of pro-fibrotic miRNAs have been identified in KFs and transfection KFs with anti-fibrotic miRNAs such as miRNA-205 and miRNA- 31, evidently can inhibit VEGF signaling. Furthermore, transfection of miRNA-637 into KFs can inhibit KFs in proliferation, migration, and collagen synthesis through TGF-β1/Smad signaling. Apoptosis and cellular senescence in KFs can also be stimulated by miRA-34 and miRNA-30. Conclusion: In the future, targets in epigenetic events such as inhibitors of methyl-transferase, histone-acetyltransferases, and histone-deacetylases, together with various miRNA, may be applied as novel agents for the treatment of keloid.
Factors that Influence The Onset of Acne Vulgaris :Retrospective Study Asrianti, Nur Ilma; Trisniartami Setyaningrum; Yuani Setiawati; Yuri Widia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 2 (2024): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.2.2024.98-103

Abstract

Background: Acne vulgaris (AV) is a skin condition that mostly occurs in adolescents, although it can occur at any age. Most occur during adolescence, with a prevalence of around 85%. Acne vulgaris is a multifactorial disease triggered by many factors, namely, genetics, environment, hormonal and emotional stress, food, trauma, cosmetics, and medications. Purpose: This study identifies the precipitating factors of acne vulgaris. Methods: This study was retrospective based on medical record data at the Dermatology and Venereology Outpatient Clinic of Dr. Soetomo General Academic Hospital Surabaya in the period January 2018–December 2019. Results: The number of AV patients within 2 years from January 2018 to December 2019 obtained 517 cases of acne vulgaris patients with complete data. There were female AV patients (80.7%) and male AV patients (19.3%). The most common age of AV patients was 15–24 years old (60.5%), the most common occupation of AV patients was student (59.8%), and patients suffered from AV for >12 months (18.6%). The most precipitating factors for AV are hormonal (69.6%) and cosmetic (50.1%); the most common type of AV is mild AV (64.2%); and the most common AV therapy is the combination of topical tretinoin, benzoyl peroxide (BPO), and topical clindamycin. Conclusion: The results of this study showed that hormonal and cosmetic precipitating factors caused most AV patients in women.

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