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INDONESIA
Berkala Ilmu Kesehatan Kulit dan Kelamin
Published by Universitas Airlangga
ISSN : 19784279     EISSN : 25494082     DOI : 10.20473
Core Subject : Health, Science,
Arjuna Subject : -
Articles 505 Documents
A Rare Self-Limiting Adamantiades Behcet Diseasen in A Woman: A Case Report Fajrin, Farah Meriana; Damayanti; Hidayati, Afif Nurul; Murtiastutik, Dwi Murtiastutik; Astindari, Astindari; Widyantari, Septiana; Sari, Maylita
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.75-80

Abstract

Background: Adamantiades–Behçet is a genetically determined disorder with a probable environmental triggering factor and is an inflammatory disease representing vasculitis. Chronic relapsing progressive course, Dapson prevents problems in other organs. Case Report: A 31-year-old woman with chief complaints of a progressive painful ulcer on her genitalia in the last month, covered by pus and with a bad odor, and also recurrent tongue sores that healed spontaneously. Multiple partner sexual intercourse, joint pain, and an eye complaint were denied. Her husband has no history of previous sexually transmitted diseases. The labia majora region showed a solitary ulcer, sharply marginated, and covered with pus. The Haemophilus ducreyi, pathergy, VDRL, TPHA, and rapid test HIV all came back negative. Enterococcus faecalis, found in bacterial culture, is sensitive to Penicillin and glycopeptide. Histopathologically recited vasculitis with thrombus in the blood vessel marks Behcet disease. The patient was given Mefenamic Acid (3x500mg), doxycicline (2x100 mg), and a wet dressing. The ulcer decreased in size after 3 weeks of treatment. Discussion: Adamantiades-Behçett disease is characterized by chronic, recurrent oral aphthous ulcers, genital ulcers, skin lesions, ocular lesions, and arthritis or arthropathy. Viral and bacterial infections have been implicated in initiating immunopathologic pathways. The pathergy test is pathognomonic, but it is not specific and often gives a negative result. Histopathological examination is still the best option to establish the diagnosis. 
Nevus Unius Lateris (NUL) in a Theree-Year-Old Child Treated by Tretinoin 0.025%, Desoxymethasone 0.25%, and Urea 20% Cream Stephanie, Aurelia; Vibriyanti Karna, NLP Ratih; Karmila, IGAA Dwi; Laksmi, Hermina; Stella, Aurelia
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 2 (2024): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.2.2024.149-152

Abstract

Background: Linear verrucous epidermal nevus is the most frequent variant of the epidermal nevus classification. Linear verrucous epidermal nevus is characterized by the proliferation of epithelium arranged in a configuration that follows Blaschko's line. Nevus unius lateris (NUL) is a variant of the verrucous epidermal nevus, which has a unilateral distribution of lesions. Lesions are usually found at birth or in the first year of life as brown to grey verrucous papules or papillomatous plaques. The management of NUL is challenging as the results are varied and there is a high risk of recurrence. Purpose: to report a case of NUL and its management, especially in children. Case: A 3-year-old girl presented with brownish spots and multiple small lumps on the left buttock that have extended to the left leg since she was 9-days-old. On dermatologic examination, there were numerous hyperpigmented verrucous papules and plaques along the Blaschko line over the affected area. In this case, the diagnosis of NUL, is based on clinical symptoms and dermoscopy examination showed multiple large brown oval or round structures with hyperpigmented brown border. The patient was treated with combination topical therapy of tretinoin 0.025%, corticosteroid desoxymethasone 0.25%, and urea 20% cream, and the lesion improved within four weeks. Discussion: Epidermal nevus is often cosmetically disturbing. The treatment is still challenging and various, including surgical and non-surgical, but none is ideal and could potentially recur over months or years. dst. 
Overlapping Primary and Secondary Syphilis in a Bisexual Patient with Human Immunodeficiency Virus Lita Setyowatie; Wika Umayatul Choiroh
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 2 (2024): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.2.2024.153-161

Abstract

Background: Syphilis and HIV are diseases that can be transmitted through sexual contact. Bisexual groups have a higher potential for HIV and syphilis transmission. In syphilis patients who have been infected with HIV, secondary syphilis often occurs along with primary syphilis, which can be found 2-3 times more often than in those who are not infected by HIV. Case: A 24-year-old male with HIV who is a bisexual man, complained chancre on his scrotum and on the tip of the penis that was painless and also has condyloma lata around the anus. Dermatological examination revealed multiple papules, patches, and plaques. The serological results for VDRL and TPHA were reactive. Histopathology examination of skin plaque suggests secondary syphilis. The Patient was diagnosed with overlapping primary-secondary syphilis and given therapy with single-dose intramuscular injection of benzathine penicillin G. Discussion: Bisexual groups have a higher potential for HIV and syphilis transmission. In HIV patients, primary and secondary syphilis often overlap. This was due to changes in the immune system causing the spread of Treponema pallidum more quickly and slowing the healing of primary lesions. Conclusion: Overlapping of primary and secondary syphilis in bisexual patients with HIV is common; in addition, the appearance of skin lesions in secondary syphilis can resemble other diseases, so confirmation by histopathology examination needs to be done.
Dermatology Life Quality Index (DLQI) Score in Acne Vulgaris after Epigallocatechin-3-Gallate (EGCG) 3% as an Adjuvant of Tretinoin 0,025% Cream Fajrin, Farah Meriana; Citrashanty, Irmadita; Listiawan, Muhammad Yulianto; Rahmadewi, Rahmadewi; Utomo, Budi; Murtiastutik, Dwi; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.177-181

Abstract

Background: Acne vulgaris (AV) often occurs at the age of puberty, most people with AV feel ashamed of their appearance. It has been believed that green tea contains high level antioxidant, such as Epigallocatechin-3-gallate (EGCG). Purpose: This study is to compare quality of life from the patient of acne vulgaris before and after using 3% Epigallocatechin-3-Gallate (EGCG) cream as adjuvant therapy of 0,025% tretinoin cream with 0,025% tretinoin cream alone in the treatment of AV. Methods: This study is a quasi-experimental study with a pre-test and post-test design, and a control group design aiming to know the difference in quality of life of 46 samples after administration of EGCG cream combined with tretinoin cream compared to the group that was given tretinoin cream alone in patients with AV for 12 weeks, and then evaluate patients satisfaction and change in quality of life after treatment using the Dermatology Life Quality Index (DLQI). Result: Statistical analysis found that there was a significant difference (p-value <0.05) in the quality-of-life value of research subjects in the treatment group when compared between the initial arrival to week 12 with a p-value of 0.000. Distribution of DLQI values in research subjects who were given 3% EGCG cream therapy as adjuvant therapy with 0.025% tretinoin cream. Conclusion: Both groups showed an improvement in the DLQI value with the interpretation of the DLQI value at week 12 being both 100%, but the treatment groups DLQI decline faster than the control groups.
Comparison between Celphane Taping and Skin Scrapping Method for KOH Examination In Dermatopohytosis Diagnosis Wibowo, Antonius; Nugrahaningrum, Sulistya; Suryaningsih, Betty Ekawati; Ramadhan, Tiar; Tussqyah, Nada; Rachmawaty, Farida Juliantina
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.168-171

Abstract

Background: Fungal skin infections are prevalent in developing countries, with dermatophytosis and tinea versicolor being the most prevalent. The KOH test is a practical and easy-to-do examination for diagnosing superficial fungal skin infections on an outpatient basis. Skin scraping is the most known method for collecting samples for KOH testing, but some studies have shown that cellophane tape is also used for a more patient-friendly approach. Purpose: This study is aimed at comparing KOH examinations using cellophane tape and skin scrapings. Methods: This research is a diagnostic test study with a cross-sectional approach. The research data were obtained from 51 medical records of skin patients at Dr. Soedirman Kebumen Municipal Hospital with the diagnosis of tinea cruris and tinea corporis who underwent KOH examination with cellophane tape and skin scrapings. Data correlation was analyzed using the Chi square test.  Result : From the research, it was found that there was no statistically significant difference between the use of cellophane tape and skin scrapings in the KOH test sampling for tinea cases (p = 0.153), which indicates that there was no significant difference between the use of the two methods for the diagnosis of dermatophytosis. Conclusion: The tapping method as an alternative method of skin scraping for KOH examination can be used to establish the diagnosis of dermatophytosis.
Epidemiologic Profile of Seborrheic Keratosis and Acrochordon at the National Referral Hospital in Indonesia Purbasari, Lusiana; Larasati, Anindya; Paramitha Wibawa, Larisa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.182-186

Abstract

Background: Seborrheic keratosis (SK) and acrochordon are common benign neoplasms of the skin thatan be diagnosed clinically.  Management of SK and acrochordon has a wide range of purposes, including aesthetic appearance and health concerns. Epidemiologic data for these entities is rare in Indonesia. Purpose: To determine the epidemiology of SK and acrochordon patients at the Dermatology & Venereology (DV) Clinic, dr. Cipto Mangunkusumo National Central General Hospital (RSCM). Method: Patient registry data at the DV Clinic, RSCM from 2014 to 2017 was collected retrospectively. Data was obtained by using the total sampling method and retrieving characteristics such as age, sex, and outpatient-based procedures. Result: In the four-year period, there were 1.202 SK patient visits with 447 new cases and 374 acrochordon patient visits with 169 new cases. The proportion of SK patients in this study was 2.2%; acrochordon was 1.8% of all patients at the DV Clinic of RSCM. The highest prevalence of SK was found in patients older than the 6th decade, while for acrochordon, it was within the 4th decade. Both SK and acrochordon were seen higher in women, with a male-to-female ratio of 1:2. Electrosurgery was the most common office procedure performed. Conclusion: Seborrheic keratosis and acrochordon proportion, respectively, are 2.2% and 1.8% at the DV Clinic, RSCM. Seborrheic keratosis and acrochordon are more frequent in women, with the peak occurring in 6th decade and 4th decade, respectively
Comparison of Acne Degree among Users of Disposable and KN95 Masks Asrinawaty, Andi Nur; Salman, Mohammad; Sofyan, Asrawati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.1-5

Abstract

Background: Maskne is a variant of acne that arises from wearing a mask. One factor that influences the incidence of maskne is the type of mask. Purpose: To compare the degree of acne vulgaris in disposable and KN95 mask wearers. Methods: This research was a cross-sectional descriptive study. The sample used was 444 people with acne vulgaris due to the use of disposable and KN95 masks. Acne vulgaris is classified based on the degree of acne. Data were analyzed bivariately using the Chi-square test. Result: This study shows no significant difference between the type of mask and the incidence of acne vulgaris (p = 0.70,p> 0.05). Conclusion: There is no difference in the degree of acne vulgaris in the incidence of maskne in individuals wearing disposable and KN95 masks.
The Effect of Sun Exposure on the Severity Degree of Photoaging and Skin Hydration on Service Workers at dr. Zainoel Abidin Regional General Hospital Banda Aceh Wahyu Lestari; Dinda Ayu Puspita; Muhammad Mizfaruddin; Sitti Hajar
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.214-218

Abstract

Background: Photoaging is the aging of the skin characterized by the appearance of wrinkles, telangiectasis, solar elastosis, pigmentation and keratosis. Photoaging is usually caused by external factor, such as sun exposure. The radiation from the sun causes an increase of the reactive oxygen species (ROS). Cell damage, dry skin, photoaging, and skin cancer are all caused by the accumulation of ROS in the skin. Purpose: The goal of this study is to find out how sun exposure affects the severity of photoaging and skin hydration at dr. Zainoel Abidin Regional General Hospital Banda Aceh. Methods: This is an analytic observational study with an accidental sampling technique. Sun exposure was   measured by a questionnaire, the severity of photoaging was assessed based on the doctor's diagnosis, and skin hydration was assessed through an examination using a corneometer and tewameter.  Results: This study indicates that there is an effect of sun exposure and the severity of photoaging with p value of 0.016, while skin hydration shows a significant effect of sun exposure on hydration with a corneometer parameter with a p value of 0.031 Conclusion: There is a substantial correlation between sun exposure and the severity of photoaging. There is a substantial relationship between sun exposure and skin moisture, as measured by the corneometer parameter.
Disability Level of Leprosy Patients in Ambon City, Maluku: A Retrospective Study from Eastern Indonesia Pangestu, Juan Felix; Manuputty, Amanda Gracia; Asmin, Elpira; Tanamal, Rita; Titaley, Christiana Rialine; Tahitu, Ritha; Bandjar, Fitri Kadarsih
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 3 (2023): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.3.2023.172-176

Abstract

Background: Leprosy, also known as Hansen's disease, is a chronic endemic disease. The Corona Virus Disease 2019 (COVID-19) pandemic disrupted the implementation of the Neglected Tropical Diseases (NTDs) program such as the leprosy new case detection program. Leprosy is one of the chronic diseases that causes various problems due to the disability it causes. Purpose: To know the prevalence of leprosy and disability in 2018-2022 in Ambon City, Maluku, Indonesia. Methods: This research is a type of retrospective descriptive research whose aim is to find out the  epidemiology of leprosy patients in Ambon City, Maluku, Indonesia with a sample of were 131 people from 2018 to 2022. Result: The prevalence of disability levels 0 and 2 has the highest percentage in the 5-year span, occurring in 2019. However, during the COVID -19 pandemic, cases of level 1 disability tend to rise. Conclusion: Leprosy patients who had disability were more common  than those who had a disability.
Zoliflodacin, A Novel Antimirobial Agent Against neisseria Gonorhoeae: A Systematic Rreview of Quasi-Experimental Studies Matthew, Franklind; Stella, Maureen Miracle; Tandarto, Kevin; Regina, Regina
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.68-74

Abstract

Background: The gram-negative bacteria Neisseria gonorrhoeae is the source of the STI known as gonorrhea. N. gonorrhoeae can adapt well to humans as a host and become a pathogen with sophisticated mechanisms to avoid the innate immune response as well as suppress the adaptive immune response. Lately, zoliflodacin was shown to have antibacterial activity against N. gonorrhoeae. Purpose: The aim of this study is to evaluate the antibacterial activity of zoliflodacin against N. gonorrhoeae. Methods: We followed the PRISMA 2020 guidelines to systematically search and collect literature in the following databases: ProQuest, EBSCOhost, PubMed, ScienceDirect, Taylor&Francis, SAGE, JSTOR, and Wiley, without time limitation (until October 9th,  2022). Titles and abstracts were reviewed for relevance. The inclusion criteria were original article written in English that investigated the effects of zoliflodacin in patients with gonorrhea. From 177 studies, we retrieved five studies for this study, published between 2015 and 2021. Results: Zoliflodacin was highly active in vitro against N. gonorrhoeae isolates from European countries, China, Thailand, and South Africa, and also showed potent antimicrobial activity against multi-resistant N. gonorrhoeae isolates in South Korea. There were three different kinds of minimum inhibitory concentration (MIC) evaluated, with the following results: modal MIC (0.064-0.25 μg/mL), MIC50 (0.03-0.125 μg/mL), and MIC90 (0.06-0.25 μg/mL). There was no cross-resistance to antimicrobials currently or previously used for gonorrhea treatment. This MIC range could be used for further studies.