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MEDISAINS
Published by Universitas Muhammadiyah Purwokerto
ISSN : 16937309     EISSN : 26212366     DOI : -
Core Subject : Health,
Medicine & Pharmacology Nursing Public Health
MEDISAINS: Jurnal Ilmiah Ilmu-ilmu kesehatan merupakan sarana penyebarluasan ilmu pengetahuan, riset, teknologi dan inovasi dibidang kesehatan yang diterbitkan tiga kali dalam setahun (April, Agustus dan Desember). Jurnal Medisains adalah jurnal peer reviewed dan Open-Access yang dikelola oleh Fakultas Ilmu Kesehatan Universitas Muhammadiyah Purwokerto dan di terbitkan dibawah Lembaga Publikasi Ilmiah dan Penerbitan (LPIP) Universitas Muhammadiyah Purwokerto.
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Articles 290 Documents
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Development and evaluation of a TinyML-based sensor fusion system for medical waste classification on low-cost embedded devices Afriani, Dini; Fadil, Irfan
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 1 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i1.29422

Abstract

Background: Medical waste management in resource-limited healthcare facilities remains dominated by manual segregation, which is error-prone and difficult to standardize. Existing automated solutions often rely on cloud-based deep learning or high-cost hardware, limiting real-time deployment at the point of waste generation. Objective: This study aimed to develop and evaluate a medical waste classification system integrating Tiny Machine Learning (TinyML) and multi-sensor fusion on a low-cost embedded device to achieve accurate, real-time, and resource-efficient on-device inference. Method: An experimental system design approach was employed, including dataset construction, model development, and embedded deployment. A TinyML-optimized MobileNetV2 model was integrated with heterogeneous sensor fusion and evaluated under embedded constraints to assess classification performance, latency, and memory usage. Result: The vision-only model achieved an accuracy of 84.5%, with frequent misclassification of sharps waste. After integrating sensor fusion, overall accuracy increased to 96.5%, and recall for sharps reached 98%. The system demonstrated efficient on-device inference with an average latency of 280 ms and low memory consumption (<1 MB). Conclusion: The proposed TinyML-based sensor fusion system provides a robust, accurate, and cost-effective solution for automated medical waste classification. This approach enhances healthcare worker safety and supports scalable deployment in resource-limited healthcare environments.
Transport index in lymphoscintigraphy for patients with lymphedema: a case report Kurniawati, Yulia; Elliyanti, Aisyah; Zahra, Rahmi
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 1 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i1.29636

Abstract

Background: Lymphedema is an interstitial edema caused by impaired lymphatic drainage. Lymphoscintigraphy is a functional imaging modality used to evaluate lymphatic flow and diagnose lymphedema, with interpretation performed qualitatively and semi-quantitatively using the Transport Index (TI). Case Presentation: Four patients with progressive unilateral extremity swelling at RSUP M. Djamil Hospital underwent lymphoscintigraphy. Subcutaneous injections of 99mTc-albumin nanocolloid were administered into both extremities, followed by dynamic and delayed imaging up to three hours after injection. Two patients showed complete lymphatic obstruction with TI scores of 36, while contralateral extremities demonstrated normal lymphatic transport (TI 1.2). The remaining two patients showed delayed lymphatic drainage with TI scores of 10.2, whereas contralateral extremities demonstrated near-normal TI values (1.2–4.2). TI values <10 indicate normal lymphatic transport, whereas values ≥10 reflect lymphatic dysfunction. Conclusion: Qualitative and semi-quantitative analyses using the Transport Index provide consistent results in evaluating lymphatic dysfunction. Lymphoscintigraphy combined with TI scoring offers an objective and reproducible approach to improve diagnostic accuracy and support clinical decision-making, including treatment planning and disease monitoring.
Anti-inflammatory and hepatoprotective effects of Moringa oleifera fruit in obesity-induced liver injury Susantiningsih, Tiwuk; Thadeus, Maria Selvester; Citrawati, Mila; Setyaningsih, Yuni
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 1 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i1.30081

Abstract

Background: Hepatic metabolic disorders are closely associated with obesity and are characterized by systemic inflammation and liver injury. Moringa oleifera fruit contains various bioactive compounds with potential anti-inflammatory and hepatoprotective properties. However, evidence regarding its effects on obesity-induced liver injury remains limited..   Objective: This study aimed to evaluate the anti-inflammatory and hepatoprotective effects of Moringa oleifera fruit extract in an obesity-induced rat model..   Methods: This experimental study used 30 male Sprague-Dawley rats divided into five groups: normal control (N), obese control (O), obese rats treated with Moringa oleifera fruit extract at 500 mg/kg body weight once daily (OEMO1), twice daily (OEMO2), and obese rats treated with vitamin C (OC). Systemic inflammation was assessed by measuring serum C-reactive protein (CRP) levels using ELISA, while hepatic changes were evaluated through biochemical markers and histopathological analysis. Data were analyzed using one-way ANOVA followed by post hoc testing.   Results: Obese rats exhibited significantly elevated serum CRP levels and marked hepatic alterations compared to normal controls (p < 0.05). Administration of Moringa oleifera fruit extract significantly reduced CRP levels and improved hepatic histoarchitecture in obese rats, with the greatest effect observed in the twice-daily treatment group (OEMO2) (p < 0.05). The effects were comparable to or greater than those observed with vitamin C. Conclusions: Moringa oleifera fruit extract demonstrates significant anti-inflammatory and hepatoprotective effects in an obesity-induced rat model, suggesting its potential as a natural therapeutic agent for obesity-related liver injury.
Effectiveness of wamena pugima honey on incision wound healing: an experimental study Kismiyati; Jumu, La; Felle, Zeth Robert
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 1 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i1.30299

Abstract

Background: Honey contains bioactive compounds that may accelerate wound healing; however, its therapeutic effectiveness varies depending on botanical origin. Wamena Pugima honey, a local Papuan honey, is presumed to possess unique bioactive properties due to endemic flora, yet its efficacy in wound healing has not been scientifically evaluated. Objective: This study aimed to evaluate the effectiveness of Pugima honey on incision wound healing using a Swiss Webster mouse model. Methods: his experimental study employed a randomized controlled design involving 36 male Swiss Webster mice, randomly allocated into three groups (n = 12 per group): positive control 1 (C1, 3% oxytetracycline ointment), combination control (C2, oxytetracycline ointment plus Pugima honey), and treatment group (P1, Pugima honey). Phytochemical screening was conducted to identify bioactive compounds. Wound length was measured on Days 3, 7, 9, 13, and 14, and wound contraction percentage was calculated accordingly. Statistical analysis was performed using the Kruskal–Wallis test followed by Dunn’s post hoc test. Results: Phytochemical screening revealed the presence of flavonoids, phenols, tannins, and saponins, indicating potential anti-inflammatory and antibacterial properties. The Pugima honey group (P1) demonstrated significantly accelerated wound healing compared to both control groups, with shorter wound length observed as early as Day 3 (10.50 ± 1.83 mm vs. 14.00 ± 1.12 mm in C1; p = 0.001). Conclusions: Pugima honey significantly enhances incision wound healing, particularly during the early to intermediate phases, and shows potential as a natural therapeutic agent for wound management.
Development and feasibility testing of a digital discharge planning application for fall risk prevention Mustikaningsih; Suroso, Jebul; -, Yektiningtyastuti; Purwito, Dedy
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 1 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i1.30319

Abstract

Background: Patient falls remain a major safety concern in hospital settings, particularly during care transitions and after discharge. Conventional discharge education is often unstructured, inconsistently delivered, and difficult for patients and families to revisit after leaving the hospital. In addition, the limited availability of integrated digital tools constrains effective patient education, documentation, and monitoring, highlighting the need for innovative discharge planning solutions. Objective: This study aimed to develop and evaluate the feasibility of a digital discharge planning application for fall risk prevention, with a focus on improving patient knowledge and nurse compliance. Methods: This development study employed a needs-based design approach to create a mobile application integrating fall risk assessment, structured discharge education, and nurse compliance monitoring within a unified digital system. Preliminary evaluation used a pre-experimental one-group pretest–posttest design involving 30 hospitalized patients at risk of falls and 30 nurses. Patient knowledge was assessed using a 10-item questionnaire, while nurse compliance was measured using a structured checklist. Data were analyzed using the Wilcoxon signed-rank test. Results: The developed application, named “Si-Patuh,” demonstrated good usability and practical applicability in clinical settings. Patient knowledge scores increased significantly from a median of 0 (range: 0–5) before intervention to 10 (range: 7–10) after intervention (Z = –4.837; p < 0.001; r = 0.88). Nurse compliance scores also improved significantly from a median of 5 (range: 0–10) to 10 (range: 9–10) (Z = –4.563; p < 0.001; r = 0.83). The application effectively integrated patient education and nurse adherence within a structured digital discharge planning framework. Conclusion: The application is a feasible, innovative solution for strengthening discharge planning by improving patient knowledge and nurse compliance with fall prevention. This integrated digital approach has the potential to enhance patient safety and continuity of care in hospital settings.
Development and evaluation of an Android-based application to enhance disaster preparedness among maternal populations Saputri, Lita; Fitriah, Iin Prima; Merry, Yussie Ater; Faridah; Bebasari, Mardiani; Eravianti; Kornelia, Kori; Darni, Resmi
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 1 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i1.30371

Abstract

Background: Natural disasters pose significant risks to vulnerable populations, particularly pregnant, postpartum, and breastfeeding women, who face increased health and safety challenges during emergencies. Strengthening disaster preparedness through accessible educational strategies is essential to improve resilience and reduce adverse outcomes. Objective: This study aimed to develop and evaluate an Android-based application as an educational tool to enhance disaster preparedness among maternal populations. Methods: This study employed a Research and Development (R&D) approach based on the Borg and Gall model, followed by feasibility and effectiveness evaluation. Data were collected through interviews, validation assessments, and structured questionnaires. The application was tested among pregnant, postpartum, and breastfeeding women using a pretest–posttest design to assess changes in disaster preparedness knowledge. Results: The developed application, named “Ibu Siaga Bencana,” demonstrated high content and media validity. Preliminary testing showed good usability and practicality. Effectiveness evaluation indicated a 40% increase in participants' disaster preparedness knowledge following application use, suggesting a substantial improvement in understanding. Conclusion: The application is a feasible and effective educational tool for improving disaster preparedness among maternal populations. Further studies with larger samples and more rigorous designs are needed to confirm its effectiveness and long-term impact.
Designing a stakeholder-informed digital learning model integrating virtual reality and e-learning for complementary therapy-based postpartum preeclampsia education Rini, Susilo; Sandi, Arif Setia; Ma’rifah, Atun Raudotul; Maya, Raden Ayu Aminah
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 1 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i1.30532

Abstract

Background: Postpartum preeclampsia remains a significant contributor to maternal morbidity and mortality in Indonesia. Midwives, as frontline maternal health providers, are expected to deliver holistic care; however, structured learning models integrating complementary therapies within digital education platforms remain limited. Although virtual reality (VR) and e-learning have been widely applied in healthcare education, their context-sensitive integration into postpartum preeclampsia management training has not been sufficiently explored. Objective: This study aimed to explore stakeholder perspectives and to design a stakeholder-informed conceptual digital learning model integrating complementary therapies into VR- and e-learning-based midwifery education. Methods: This qualitative exploratory study involved 31 participants, including practicing midwives, educational practitioners, policymakers, and clinical and technology experts in Banyumas Regency, Indonesia. Data were collected through focus group discussions and semi-structured in-depth interviews and analyzed using thematic analysis to identify stakeholder perspectives, contextual challenges, and design requirements informing the development of a conceptual digital learning model. Results: Four interconnected themes were identified: 1) fragmented integration of complementary care; 2) the need for experiential and clinically contextualized learning; 3) digital readiness and structural constraints; and 4) the importance of institutional support and policy alignment. These findings informed the development of a stakeholder-informed conceptual framework consisting of structured curriculum modules, a nine-scene VR storyboard simulating clinical decision-making, and a mobile-accessible Learning Management System integrating complementary therapies such as lavender aromatherapy, warm foot bath, and slow-stroke back massage. Conclusion: This study provides a contextually grounded digital learning framework for integrating VR, e-learning, and complementary therapies in postpartum preeclampsia education. The proposed model offers a foundation for future pilot implementation and effectiveness studies to evaluate its impact on midwifery competencies and clinical practice.
Development and content validation of a multidimensional assessment instrument for patients with cancer: a Delphi study Wahyu Dewi Sulistyarini; Marina Kristi Layun Rining; Vera Veriyallia; Rifdinia Bregita; Samuel Kevin Ruslim; Agustinus Darmadi Haryanto; Lidya Vera Sianturi; Christantie Effendy; Aminah; Reza Heddy Aprinda
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 2 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i2.30392

Abstract

Background: Although several assessment instruments are available for patients with cancer, most focus primarily on physical symptoms and do not comprehensively assess patients' physical, psychological, social, and spiritual needs. Objective: This study aimed to develop a multidimensional assessment instrument for patients with cancer and evaluate its content validity. Method: An instrument development study was conducted through literature review, item synthesis, and a two-round Delphi process involving 12 multidisciplinary experts. An initial 37-item instrument covering physical, psychological, social, and spiritual domains was developed. Content validity and expert consensus were evaluated using the Item-level Content Validity Index (I-CVI) and interquartile range (IQR). Results: Of the initial 37 items, 35 were retained following two Delphi rounds. Fifteen items were revised to improve clarity and conceptual alignment, whereas two psychological items were removed because of insufficient content validity and conceptual inconsistency. The final instrument comprised 35 items representing four multidimensional domains, with acceptable expert consensus across all retained items. Conclusion: The developed 35-item multidimensional assessment instrument demonstrated satisfactory content validity and expert consensus. It provides a preliminary framework for comprehensively assessing the multidimensional needs of patients with cancer and supports further psychometric evaluation before clinical implementation.
Factors associated with maternal compliance with food safety principles in supplementary food management: a cross-sectional study Wahyu Ersila; Suparni Suparni; Siti Khuzaiyah; Syavira Nooryana; Susri Utami
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 2 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i2.30677

Abstract

Background: Food safety is essential for protecting the health and nutritional status of young children because unsafe food preparation, handling, and storage increase the risk of infection, undernutrition, and impaired growth. However, evidence on the combined influence of maternal, psychological, and environmental factors on maternal compliance with food safety principles in supplementary food management remains limited. Purpose: This study aimed to identify factors associated with maternal compliance with food safety principles in supplementary food management for children aged 6–59 months. Methods: An analytical cross-sectional study was conducted among 1,634 mothers of children aged 6–59 months in Pekalongan Regency, Central Java, Indonesia. Participants were recruited using consecutive sampling. Data were collected through a structured online questionnaire. Associations were examined using chi-square tests and multivariable binary logistic regression, with results reported as adjusted odds ratios (AORs) and 95% confidence intervals (CIs). Results: Maternal age, educational level, employment status, household income, and knowledge were not independently associated with compliance. In contrast, positive attitudes were associated with approximately threefold higher odds of compliance (AOR = 3.094; 95% CI: 2.366–4.045), whereas high motivation demonstrated the strongest association (AOR = 8.675; 95% CI: 6.654–11.311). Adequate facilities and infrastructure support were also associated with higher compliance (AOR = 1.909; 95% CI: 1.475–2.472). Conclusion: Maternal attitudes, motivation, and infrastructure support were independently associated with compliance with food safety principles. Interventions integrating behavioural change strategies with improvements in household food preparation environments may strengthen safe supplementary food management.
Effects of an Islamic health education module on spirituality and medication adherence among older adults with chronic diseases: a sequential explanatory mixed-methods study Fatnan Setyo Hariwibowo; Kusbaryanto Kusbaryanto
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Vol. 24 No. 2 (2026)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v24i2.24664

Abstract

Background: Medication adherence among older adults with chronic diseases is influenced by clinical, behavioral, psychosocial, and spiritual factors. However, structured health education integrating Islamic spiritual values remains limited in Indonesia. Purpose: This study aimed to evaluate changes in spirituality and medication adherence following an Islamic health education intervention and to explore participants’ experiences of the intervention. Methods: A sequential explanatory mixed-methods design was used, consisting of a single-group pretest–posttest quantitative phase followed by a qualitative phase. The study involved 158 Muslim adults aged ≥60 years with chronic diseases at PKU Muhammadiyah Hospital Temanggung, Indonesia. Spirituality and medication adherence were assessed using the daily spiritual experience scale (DSES) and the eight-item morisky medication adherence scale (MMAS-8), respectively. Sixteen participants were subsequently selected for in-depth interviews. Results: The mean DSES score increased from 48.72±7.84 to 57.91±6.45 (mean difference=9.19; 95% CI: 8.38–10.00; p<0.001; Cohen’s d=1.79). The median MMAS-8 score increased from 5 (IQR: 4–6) to 7 (IQR: 6–8; p<0.001; r=0.28). Qualitative findings indicated that the integration of Islamic values strengthened spiritual meaning, emotional calmness, motivation, and discipline in medication-taking. However, forgetfulness, treatment fatigue, physical limitations, and dependence on family support remained barriers to medication adherence. Conclusion: The Islamic health education module was associated with improvements in spirituality and medication adherence among older adults with chronic diseases.

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