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Global Medical and Health Communication
Published by Universitas Islam Bandung
ISSN : 23019123     EISSN : 24605441     DOI : https://doi.org/10.29313/gmhc
Core Subject : Health, Science,
Dentistry Health Professions Immunology & microbiology Nursing Public Health
Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.
Arjuna Subject : Kedokteran - Epidemilogi
Articles 21 Documents
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Search results for , issue "Vol 13, No 1 (2025)" : 21 Documents clear
Early Detection of the Heavy Metals Pollution Effect on Citarum River Using Zebrafish Muscle Mitochondria Biomarkers Gene Expression Oktorina, Lenny; Goenawan, Hanna; Sylviana, Nova; Kirana, Kartika Hajar; Feriandi, Yudi; Lesmana, Ronny
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14110

Abstract

Citarum is the longest river in West Java and one of the most polluted rivers in Indonesia and the world. Heavy metals from agriculture, industry, and household waste pollute the Citarum river. Heavy metals enter humans and animals by consuming contaminated food and beverages. Several studies have identified mitochondria as a primary target for heavy metal poisoning, resulting in impaired mitochondrial energy production, induction of oxidative stress, apoptosis, and mitophagy. This study aims to investigate the impact of heavy metals from the upstream and downstream areas of the Citarum river on mitochondrial gene expression of cox4i1, sod2, baxa, mfn1b, and ppargc1a in the skeletal muscle of zebrafish (Danio rerio) using in vivo models for biological monitoring of early detection of environmental heavy metal pollution. This experimental study was conducted from December 2019 to March 2020. The study involved four treatment groups and one control group of zebrafish, which were exposed to river water and sediments collected from two sites in the Citarum river area in December 2019. The biomarker levels were analyzed using multivariate analysis. Although all heavy metal levels except mercury were below the WHO threshold in all samples, this study's results showed that the RT-PCR results indicated that the levels of cox4i1, baxa, and ppargc1a in all samples were generally higher than those in the control. There were significant differences (p<0.05) using multivariate analysis in sod2 in Cibeureum water compared to Cibeureum sediment and ppgarc1a compared to control and Balekambang sediment. In conclusion, heavy metals from the upstream and downstream areas of the Citarum river had an impact on mitochondrial gene expression of cox4i1, sod2, baxa, mfn1b, and ppargc1a in the skeletal muscle of zebrafish. Biomarkers pparc1gc and sod2 could be further studied to identify the most valid and reliable parameters for biological monitoring, which may aid in the early detection of environmental damage to humans and animals.
Designing Stimulus as Cognitive Task Stimulus for Measurement of Cognitive Bias in Online Gamers Diantina, Fanni Putri; Nawangsih, Endah; Permana, Rizka Hadian; Khasanah, Andhita Nurul; Hanifa, Fathiyya Amalia; Putri, Gitta Indriani Lestari; Shafana, Yasya Citra
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14222

Abstract

Problematic online gamers are shown to be biased towards information about gaming, focusing on it more than other subjects. Measuring cognitive processes requires tasks with specific stimuli, essential for studying decision-making. This research aims to create a gambling-related stimulus for a mental task. The research used a combination of methods. Qualitative data were gathered through interviews and focus group discussions, while quantitative data were collected through questionnaires. A total of 88 research participants were obtained by purposive sampling with inclusion criteria: aged 18–30, played games 4–10 hours daily for at least 12 months. Forty gamers participated in semi-structured interviews using an interview guide based on the Interaction of Person-Affect-Cognition-Execution (I-PACE) theoretical framework. Forty-eight gamers also took part in focus group discussions (FGDs). This research was conducted in Bandung from November 2023 to October 2024. The data were analyzed using NVivo-14 software and descriptive statistics. As a result, various stimuli were obtained, including 597-word stimuli, 87 image stimuli, and 97 audio stimuli. It was hypothesized that these stimuli would evoke a strong association with online games, prompting gamers to devote greater attention when encountering them, whether in visual, textual, or audio formats.
Panoramic Radiography Measurements Not Correlated with BMD Results in End-stage Chronic Kidney Disease Patients Ni'ami, Muhamad Aufa; Ferriastuti, Widiana; Rahardjo, Paulus
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14182

Abstract

Chronic kidney disease (CKD) is a disorder of the kidney defined by a glomerular filtration rate of less than 60 ml/min/1.73 m2 for a minimum of three months, progressive and irreversible. One complication is chronic kidney disease-metabolic bone disorders (CKD-MBD), which can cause osteoporosis. This is diagnosed using bone mineral densitometry-dual energy absorptiometry (BMD-DXA) and panoramic radiographs, which can also detect thinning of the mandibular cortex in patients with CKD. This study aims to determine the correlation between osteoporosis images on panoramic photos with the results of lumbar and hip areal T-scores in chronic kidney disease (CKD). This research is an observational study with a prospective approach and cross-sectional design. The subjects of this study were 52 patients with chronic kidney disease (CKD). Undergoing hemodyalize procedure (HD) at Dr. Soetomo General Hospital for February–March 2024. Data was collected by taking the results of the panoramic photo examination and BMD-DXA to see the results of the T-score in each patient—data analysis using the Spearman test on SPSS software. Which resulted in the p-values for the panoramic mandibular index (PMI), mandibular cortical width (MCW), and mandibular cortical index (MCI) with a lumbar T-score range of 0.093 to 0.676 and the PMI, MCW, and MCI with left-right hip T-score, the p-values ranged from 0.318 to 0.970 (all p-values >0.05). It can be concluded that there is no correlation between the results of the T-score for the lumbar and hip regions and the measurements of PMI, MCW, and MCI. Therefore, employing these three measurements as a standard for osteoporosis screening using panoramic x-rays is not feasible.
Role of Chest CT Scan to Predict Malignancy on Mediastinal Mass Widyaningrum, Saraswati; Widyoningroem, Anita; Sensusiati, Anggraini Dwi; Kusumastuti, Etty Hary
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14218

Abstract

Mediastinal mass is becoming a global health problem due to high mortality. The heterogeneous mediastinal components make the symptoms of mediastinal mass diverse. CT scans are still the imaging modality for examining mediastinal mass before surgery or other therapies. In this study, we evaluate whether a CT scan could predict the malignancy of mediastinal mass, which is expected to help establish a pre-surgical or pre-biopsy diagnosis. Sixty-two samples were taken consecutively from mediastinal mass patients who came to Dr. Soetomo General Academic Hospital to undergo a CT scan of the thorax with contrast and histopathology examination (core biopsy or open biopsy), which was carried out in the period from December 2019 to March 2024. The results of the CT scan imaging used in this study variable include mass location, mass shape, mass size, infiltration with surrounding organs, attenuation values before contrast administration, after contrast administration, and additional attenuation before and after contrast administration. The CT scan and histopathology results were compared, and multivariate analysis was performed to obtain predictor factors. The location of the mediastinal mass (anterior, medius, posterior), the solid heterogeny component, cystic, calcification, mass shape, organ infiltration, and contrast enhancement value could significantly predict the mediastinal mass's malignancy. If obtained simultaneously, the organ infiltration and contrast enhancement value >20 HU can indicate whether a mediastinal mass is malignant with a specificity of up to 100%.
The Role of Lumbar CT Scan Anthropometric Parameters to Predict the Height of Indonesian Adults Afriliani, Nurmilia; Setiawati, Rosy; Violetta, Lenny
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14225

Abstract

Anthropometry, the study of human body measurements, is crucial in estimating stature, which is valuable in medical research, forensic science, anthropology, and ergonomic design. While various methods exist for estimating stature, lumbar spine measurements make a significant contribution to this estimation. This study aimed to analyze the relationship between lumbar spine dimensions and stature in the Indonesian population using three-dimensional computed tomography (3D CT) scan data. This analytical observational study, employing a cross-sectional approach, was conducted at the Department of Radiology, Dr. Soetomo General Academic Hospital, Surabaya, from August to September 2023. The key measurements included heights of the posterior, anterior, and central vertebral bodies from lumbar 1 to lumbar 5 (L1 to L5), transverse pedicle diameter, pedicle axis length, vertical pedicle diameter, and overall stature. The study included 66 subjects (30 males and 36 females). Males had an average height of 165.86 cm, while females had an average height of 155.85 cm. Significant gender differences were observed in heights of the posterior vertebral body (HPVB), heights of the central vertebral body (HCVB), and pedicle axis length (PAL) measurements. HPVB of L1 can be used as a predictor of height in females (p<0.001), whereas PAL of L5 can be used as a predictor of height in males (p=0.006). Lumbar spine dimensions measured using 3D CT scans provide reliable stature predictions, with specific measurements such as HPVB from L1 in females and PAL from L5 in males showing high accuracy. These findings support the development of population-specific anthropometric tools and enhance understanding of factors influencing stature in Indonesia.
Community Participation and Mosquito Breeding Sites in Cimahi City: Current Conditions and Challenges in Dengue Fever Control Faridah, Lia; Angga, Anggisti Nurdinda Chaerany Putri; Fauziah, Nisa; Jaya, I Gede Nyoman Mindra
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14241

Abstract

In 2021, Cimahi City recorded the 5th highest dengue fever (DF) cases among 27 districts/cities in West Java. Efforts to control DF have been going on for several decades, with one strategy being to involve community participation in eliminating mosquito breeding sites. This research evaluated community participation in Cimahi city by identifying mosquito breeding locations inside and outside the home. Samples were taken from 15 sub-districts in Cimahi city. The research population involved houses in 15 sub-districts, with a total sample of 1,560 houses representing each sub-district. Larval sampling was carried out in various water reservoirs, both natural and artificial, around residential areas. The successfully taken larvae were then identified and counted in the laboratory. The research showed that the most dominant mosquito breeding place was in bucket-type containers, namely 130 units (3.2%). Entomological data produced a free larva index (FLI) of 79.23%, a house index (HI) of 20.7%, a container index (CI) of 8.07%, and a Breteau index (BI) of 20.5%. This finding indicated a lack of community involvement in preventing vector-borne diseases by eliminating breeding sites. Cimahi city still had the potential to spread vector-borne diseases.
Effect of Structured Workers Physical Exercise, Individual Factors, and Work-related Factors on Physical Fitness of Security Officers Rosady, Dony Septriana; Mirtha, Listya Tresnanti; Agustina, Amilya; Soemarko, Dewi Sumaryani; Sugiharto, Agus
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.13722

Abstract

Security officers require good physical fitness to perform their duties effectively. Maintaining this level of fitness often involves structured exercise programs that consider the frequency, intensity, duration, and type of activity. This study aims to examine the relationship between a structured physical exercise program, individual factors, and work-related factors on the physical fitness of security officers. This study was conducted in July 2023 and utilized company program data from March to June 2023, focusing on 67 security officers at PT X. Physical fitness data was collected using the Cooper test method and analyzed using SPSS. Data normality was assessed using the skewness/standard error method, with values <2 considered normally distributed. A paired sample t-test revealed a significant relationship between Cooper test distances before and after participation in the structured exercise program (p<0.001). Further analysis demonstrated relationships between changes in physical fitness and several factors: work fatigue (p<0.001), work stress dimensions (specifically work overload, role conflict, quantitative and qualitative workload excess, career development, and responsibility to others, all with p<0.014), and sleep quality (p<0.001). The coefficient of determination (r2) was 0.496, indicating that work fatigue, role conflict, and sleep quality collectively explain 49.6% of the variance in physical fitness changes. The remaining variance is likely influenced by factors not included in the model. Multivariate analysis confirmed that work fatigue (p<0.001), role conflict (p=0.036), and sleep quality (p=0.015) were predictors of changes in physical fitness. In conclusion, a structured physical exercise program has a positive influence on the physical fitness of security officers. Furthermore, work fatigue, work stress (particularly role conflict), and sleep quality are associated with changes in physical fitness among these officers.
The Relationship between Child Abuse and the Risk of Suicidal Ideation among Adolescents in Bandung City Prasetia, Ayu; Saputra, Lucky; Andayani, Santi
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14181

Abstract

The 2015 United Nations Children's Fund (UNICEF) report stated that violence against children occurs widely in Indonesia, and from the results of monitoring by the Indonesia Child Protection Commission (Komisi Perlindungan Anak Indonesia, KPAI), the increase in the number of violence against children has increased significantly from 2011 to 2015. The impact of violence on children is vast, including the increased risk of suicidal behavior. This research employed a cross-sectional method with adolescents aged 13–18 years in Bandung city. Subject selection was conducted using the consecutive sampling method. The history of violence was measured using the IPSCAN Child Abuse Screening Tool for Children (ICAST-C) Indonesian language version, and the risk of suicide ideation was calculated using the early detection of adolescent suicide ideation risk factors instrument. Data analysis uses the chi-square method and the t-independent test (unpaired). This research was conducted during the COVID-19 pandemic, and the researcher collected data online. The study was conducted in Bandung city. Data collection was carried out from May to June 2020. The results of 69 adolescents in Bandung city were 72% (50 adolescents) who experienced at least 1 type of violence, and 36% (25 adolescents) had suicidal thoughts. Teens who had experienced violence were 16.6 times more likely also to have suicidal ideation. The conclusion was found that there was a meaningful relationship between child abuse and the risk of suicidal ideation in adolescents in Bandung city.
Identification of Mitochondrial DNA Polymorphism on Linezolid-induced Toxic Optic Neuropathy Patients Setyorini, Dwi Indira; Ahmad, Zen; Amalia, Ella; Subandrate, Subandrate; Hutabarat, Yosafat Beltsazar
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14240

Abstract

Drug-resistant tuberculosis (DR-TB) is difficult to eradicate due to several factors, including insufficient treatment and medication side effects. Linezolid is among the medications with serious adverse effects. Linezolid toxicity is suspected to be related to the drug's binding to mitochondrial 16s rRNA. Some studies indicate that polymorphisms in patients' mtDNA may increase vulnerability to the development of toxic optic neuropathy. This study aims to identify a genetic influence on the vulnerability to the occurrence of toxic optic neuropathy side effects in drug-resistant tuberculosis patients receiving linezolid treatment. This research was conducted at the Faculty of Medicine, Universitas Sriwijaya, Palembang, from September to October 2023. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was undertaken to detect mutations in the G3010A mtDNA of the patients. Two patients experiencing toxic optic neuropathy side effects during drug-resistant tuberculosis treatment underwent blood sample collection. Blood samples were examined for mutations in the G3010A and A2706G genes using the PCR-RFLP method. The PCR-RFLP examination results indicated the presence of mutations in G3010A. In conclusion, polymorphism of G3010A mtDNA may contribute to the vulnerability to toxic optic neuropathy side effects in drug-resistant tuberculosis patients receiving linezolid. Further research with a larger population is needed to prove the involvement of mtDNA polymorphisms in the vulnerability to toxic optic neuropathy.
Effectiveness of Sage Leaf Gel on Neutrophil Count in Wound Healing Meliawaty, Florence; Djohan, Frita Ferlita Shafri; Ramdhani, Muhamad Syahrul
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14302

Abstract

A wound involves damage to the epithelial layer of the skin, extending to the subcutis and surrounding tissues. The body initiates a healing process starting with inflammation. Neutrophils play a crucial role in this phase; excessive neutrophils can cause tissue necrosis, while insufficient neutrophils may lead to infection. Neutrophils are essential for bacterial eradication during inflammation. Sage leaf extract, known for its anti-inflammatory, antioxidant, and antibacterial properties, may aid in wound healing. This study evaluates the effectiveness of 5% sage leaf extract gel on neutrophil count during the wound healing process in Wistar rats. This study was conducted in several Universitas Jenderal Achmad Yani Cimahi laboratories from 29 May 2023 to 23 February 2024. A post-test-only control group design was used with 25 samples divided into five groups: (K-1) no treatment, tissue sampled at 13 minutes; (K-2) no treatment, tissue sampled at 103 minutes; (KN) healthy/normal control; (KP1) 5% sage leaf extract gel, tissue sampled at 13 minutes; (KP2) 5% sage leaf extract gel, tissue sampled at 103 minutes. Data analysis was performed using the Kruskal-Wallis test followed by the Mann-Whitney post hoc test (p≤0.05), indicating a statistically significant difference. The highest mean neutrophil count was observed in the KP2 group, which received 5% sage leaf extract gel and had tissue sampled at 103 minutes. The study concludes that a 5% sage leaf extract gel is effective in increasing neutrophil counts during the healing of punch wounds in Wistar rats, which contributes to accelerated wound healing.

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