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E-Jurnal Medika Udayana
Published by Universitas Udayana
ISSN : 23031395     EISSN : 25978012     DOI : -
Core Subject : Health,
Majalah ilmiah E-Jurnal Medika Udayana menerima naskah dari mahasiswa PSPD FK UNUD, baik berupa karangan asli atau laporan penelitian, ikhtisar pustaka, laporan kasus, maupun surat-surat untuk redaksi. Naskah yang dikirimkan untuk majalah ilmiah E-Jurnal Medika Udayana adalah naskah belum pernah atau tidak akan dikirim ke majalah lain. Bahasa yang digunakan adalah bahasa Indonesia
Arjuna Subject : -
Articles 1,956 Documents
UJI EFEKTIVITASAN BUAH MOMORDICA CHARANTIA L SEBAGAI IMUNOSTIMULAN DAN ANTIPLASMODIUM TERHADAP INFEKSI PARASIT PLASMODIUM BERGHEI PADA MENCIT Semara, I Nyoman Sudha; Sri Laksemi, Dewa Ayu Agus; Damayanti, Putu Ayu Asri; Eka Diarthini, Ni Luh Putu
E-Jurnal Medika Udayana Vol 12 No 12 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i12.P11

Abstract

ABSTRAK Malaria adalah penyakit infeksi parasit Plasmodium sp. Plasmodium merupakan parasit yang menyerang sel darah merah dan dapat menimbulkan obstruksi pada kapiler organ tubuh yang vital. Kasus resisten plasmodium terhadap obat anti malaria membuat banyak penelitian yang mencoba mencari obat alternatif dari tumbuhan yang mudah diperoleh masyarakat, salah satu tanaman yang memiliki potensi yakni Momordica charantia L atau yang dikenal buah pare. Untuk mengetahui pengaruh ekstrak buah pare (Momordica charantia L) dengan dosis 100 mg/kgBB untuk antiplasmodium dan 100 mg/kgBB untuk immunostimulant terhadap derajat parsitemia pada mencit Balb/c yang diinfeksikan Plasmodium Berghei. Penelitian ini merupakan penelitian eksperimental secara In Vivo dengan menggunakan rancangan metode Randomized Post test Only Controlled Group menggunakan 24 sampel mencit yang dibagi menjadi empat kelompok yakni satu kelompok kontrol negatif antiplasmodium, satu kelompok negatif immunostimulant, satu kelompok perlakuan antiplasmodium dan satu kelompok perlakuan immunostimulant. Didapatkan hasil rerata derajat parasitemia pada kelompok kontrol negatif antiplasmodium 34.9 %, kelompok kontrol negatif immunostimulant 33.9 %, kelompok perlakuan antiplasmodium dosis 100 mg/kgBB sebesar 19.8 % dan kelompok perlakuan immunostimulant dosis 100 mg/kgBB sebesar 17.1 %. Berdasarkan hasil analisis One Way Anova ditemukan perbedaan rerata antara masing-masing kelompok kontrol dan kelompok perlakuan yakni kelompok antiplasmodium dengan nilai p value <0.001 dan kelompok immunostimulant dengan nilai p value <0.002. Hasil penelitian menunjukan ekstrak buah pare (Momordica charantia L) dapat menghambat pertumbuhan parasit Plasmodium Berghei dengan melihat perbedaan rerata masing-masing kelompok kontrol dan kelompok perlakuan, dengan masing-masing dosis kelompok yakni 100 mg/kbBB. Kata kunci: Antimalaria, Momordica charantia L, Plasmodium Berghei, Derajat Parasitemia
HUBUNGAN TINGKAT ANSIETAS DENGAN STATUS GIZI MAHASISWA FAKULTAS KEDOKTERAN UMSU Febriyanti, Eka; Isrovian, Sheila Zalfa
E-Jurnal Medika Udayana Vol 13 No 4 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i04.P01

Abstract

Ansietas merupakan suatu gangguan psikiatri yang prevalensinya meningkat pada remaja atau dewasa muda terutama pada perempuan. Sumber kecemasan pada mahasiswa kedokteran berasal dari tekanan akademik, masalah sosial, dan masalah finansial. Ansietas ini dapat memengaruhi nafsu makan sehingga dapat mengakibatkanmasalah gizi, baik gizi kurang maupun gizi lebih. Tujuan: Penelitian ini bertujuan untuk menilai hubungan antara ansietas dengan status gizi pada mahasiswa di FK UMSU. Metode: Penelitian ini merupakan penelitian Cross-Sectional yang melibatkan 96 orang mahasiswa. Subjek diperiksa berat badan dan tinggi badan untuk mengetahui indeks massa tubuh dan diminta mengisi kuesioner HARS untuk mengetahui tingkat ansietas. Data yang didapatkan dianalisis dengan Spearman Correlation. Hasil: Dari analisis data didapatkan mayoritas responden berusia diatas 20 tahun dan jenis kelamin perempuan. Dan didapatkan P <0.002 artinya terdapat hubungan antara tingkat ansietas dengan status gizi mahasiswa FK UMSU. Kesimpulan: Terdapat hubungan yang signifikan antara tingkat ansietas dengan status gizi FK UMSU. Kata kunci: Ansietas, Status Gizi, Mahasiswa Kedokteran
Hubungan Mutasi Gen K-RAS terhadap Respon Terapi pada Pasien Kanker Kolorektal di RSUP Prof. DR. IGNG. Ngoerah Tahun 2017-2019. Bramantya, Putu Arya Rahadi; Wihandani, Desak Made; Dewi, Ni Nyoman Ayu; Ruma, I Made Winarsa
E-Jurnal Medika Udayana Vol 13 No 3 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i03.P13

Abstract

K-RAS is one of the most frequently mutated genes found in colorectal cancer cases. The K-RAS gene has about 30%-40% contribution to the formation of colorectal cancer. This research is an analytic observational study with a cross-sectional design to explain the characteristics of patients with colorectal cancer at Prof. dr. IGNG. Ngoerah 2017-2019 and assessed the relationship between K-RAS gene mutations and response to therapy. The results of the chi-square test showing a significant relationship between the type of KRAS gene mutation and the response to therapy where p=0.035 (p<0.05). This shows that there is a significant relationship between mutations in the K-RAS gene in colorectal cancer and the response to therapy in colorectal cancer patients at Prof. Dr. IGNG. Ngoerah General Hospital in 2017-2019.
EFFECTIVENESS OF WEB-BASED PROGRESSIVE MUSCLE RELAXATION (PMR) ON SLEEP QUALITY IN PATIENTS BREAST CANCER UNDERGOING CHEMOTHERAPY Amelia, Weny; Sari, Dian Febrida; Syahid, Armein; Espasari, .
E-Jurnal Medika Udayana Vol 13 No 07 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i07.P02

Abstract

Breast cancer is the uncontrolled growth of cells or tissue in the breast. Chemotherapy is the first therapeutic choice for treating cancer. One of the symptoms felt by breast cancer patients undergoing chemotherapy is a decrease in sleep quality. Sleep quality is a person's sense of satisfaction with their sleep. Decreased sleep quality can reduce the body's immune system to fight developing cancer cells. The recommended nursing action to overcome sleep disorders in breast cancer patients undergoing chemotherapy is web-based progressive muscle relaxation (PMR). PMR is a technique that focuses attention on muscle activity, by identifying tense muscles and then reducing tension by performing relaxation techniques to get a relaxed feeling. The aim of this study was to determine the effectiveness of web-based PMR on sleep quality in breast cancer patients undergoing chemotherapy at RSUP Dr. M. Djamil Padang. The research design uses a quasi-experiment in the form of a one group pretest-posttest approach. The sampling technique was purposive sampling with a sample size of 25 people. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Statistical test using Paired T-Test. The results showed a significant effect of web-based progressive muscle relaxation (PMR) on sleep quality in breast cancer patients undergoing chemotherapy (p value = 0.000; ? < 0.05). In this study, it can be concluded that there is an influence of web-based progressive muscle relaxation (PMR) on sleep quality in breast cancer patients undergoing chemotherapy at RSUP Dr. M. Djamil Padang. This study recommends web-based progressive muscle relaxation (PMR) as an independent nursing intervention to improve sleep quality in breast cancer patients undergoing chemotherapy. Keywords: Progressive Muscle Relaxation (PMR); breast cancer; chemotherapy; sleep quality
GAMBARAN KLINIKOPATOLOGIK PENYAKIT PROSTAT DI RSUP SANGLAH DENPASAR TAHUN 2018-2020 Astuti, Ida Ayu Jelantik; Winarti, Ni Wayan; Sriwidyani, Ni Putu; Dewi, I Gusti Ayu Sri Mahendra
E-Jurnal Medika Udayana Vol 12 No 11 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i11.P07

Abstract

Prostate disease is one of the diseases with a high incidence among elderly men. . In establishing the diagnosis of prostate disease, histopathological and laboratory examinations are vital. These histopathological results can be grouped into 3, namely benign lesions, PIN, and carcinoma. This study aims to determine the clinicopathological description of prostate diseases at Sanglah Hospital Denpasar from 2018-2020. The cross-sectional research was conducted using the descriptive and analytic method. Samples were selected based on several inclusion and exclusion criteria. Data were analyzed using SPSS version 26 to obtain a general clinicopathological picture based on age, histopathological diagnosis, the relationship between age and histopathological, diagnosis, PSA level, and the relationship between PSA level with histopathological diagnosis, and grade group carcinoma. The results showed that the prostate disease with the most patients at Sanglah Hospital Denpasar from 2018-2020 occurred between the age of 70-79 years by 39,0% with the dominant histopathological diagnosis being benign prostate 240 (74,3%), followed by PIN 27 (8,4%), and carcinoma 56 (17,3%). There was no relationship found between age, mean age and histopathological diagnosis with p=0,881 and p=0,119. The highest PSA level was > 20ng/mL. It was found that the PSA level was significantly associated with histopathological diagnoses with a value of p=0,000. The most prevalent grade group characteristic was grade group 5 with 36 (64,3%). Keywords: Prostate Disease, Clinicopathologic, PSA Level
KARAKTERISTIK PASIEN DENGAN TUMOR JINAK MELANOSITIK PADA RUMAH SAKIT UMUM PUSAT PROF DR IGNG NGOERAH PERIODE JANUARI 2020 – DESEMBER 2022 Hendrayanta, Michelle; Darmaputra, I Gusti Nyoman
E-Jurnal Medika Udayana Vol 13 No 1 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i01.P15

Abstract

Pendahuluan: Melanosit merupakan sel penghasil pigmen pada kulit. Beberapa neoplasma jinak dapat berasal dari melanosit dan umumnya merupakan hasil dari mutasi onkogenik, dengan bentuk yang paling umum adalah nevus melanositik jinak. Tujuan: Penelitian ini bertujuan untuk mengetahui prevalensi dan karakteristik tumor jinak melanositik pada pasien yang berkunjung ke poliklinik kulit dan kelamin RSUP Prof Dr IGNG Ngoerah. Metode: Penelitian ini menggunakan desain deskriptif observasional dengan pendekatan potong lintang. Data berasal dari data sekunder rekam medis pasien tumor jinak melanositik yang berobat dan kontrol di Poliklinik Kulit dan Kelamin RSUP Prof Dr IGNG Ngoerah, periode Januari 2020-Desember 2022. Subjek penelitian diambil dari populasi yang memenuhi kriteria inklusi, yaitu pasien telah terdiagnosis secara histopatologi dengan adanya nevus dan dengan data rekam medik lengkap. Berdasarkan hasil pengumpulan dan pengolahan data pasien, diperoleh sebanyak 68 kasus yang memenuhi kriteria inklusi penelitian. Hasil: Data menunjukkan bahwa bahwa angka kejadian tumor jinak melanositik terjadi peningkatan pada tahun 2021 dan 2022. Berdasarkan jenis kelamin, lebih banyak ditemukan pada laki-laki (57,35%). Berdasarkan usia, ditemukan usia pasien terbanyak adalah 10-19 tahun (23,53%). Berdasarkan jenis nevus yang ditemukan, sebanyak 40 kasus (58,82%) merupakan nevus melanositik. Kesimpulan: Berdasarkan hasil penelitian, ditemukan bahwa tumor jinak melanositik sering terjadi pada populasi pria dan kelompok usia 10-19 tahun, dengan jenis yang terbanyak adalah nevus melanositik pada pasien yang berkunjung ke Poliklinik Kulit dan Kelamin RSUP Prof Dr IGNG Ngoerah dalam rentang waktu Januari 2020 hingga Desember 2022.
GAMBARAN PROFIL LIPID DAN RASIO NEUTROFIL LIMFOSIT PADA PASIEN SINDROM KORONER AKUT DI RSUP SANGLAH TAHUN 2021 Dharayani, Luh Anandita; Yasa, I Wayan Putu Sutirta; Lestari, Anak Agung Wiradewi; Wande, I Nyoman
E-Jurnal Medika Udayana Vol 13 No 5 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i05.P07

Abstract

Sindrom koroner akut (SKA) merupakan kumpulan gejala yang dikarenakan jantung mengalami penurunan volume aliran darah akibat plak aterosklerosis. Plak ini dapat dipengaruhi oleh profil lipid pada pasien SKA. Untuk mengetahui karakteristik, gambaran profil lipid dan rasio neutrofil limfosit pasien sindrom koroner akut, telah dilakukan penelitian dengan menggunakan metode deskriptif cross-sectional. Lokasi penelitian ini dilaksanakan di RSUP Sanglah Denpasar menggunakan rekam medis sebagai data sekunder. Hasil penelitian menunjukkan 362 sampel dengan kesimpulan terbanyak jenis kelamin laki-laki. Kasus terbanyak terjadi pada pasien kelompok umur masa manula, yaitu >65 tahun, dengan diagnosa terbanyak pada STEMI. Berdasarkan profil lipid yaitu kolesterol total terbanyak kategori baik, LDL terbanyak kategori optimal, HDL terbanyak kategori rendah, dan trigliserida terbanyak kategori normal. Selanjutnya, rasio kolesterol total/HDL, rasio LDL/HDL, rasio trigliserida/HDL, dan rasio neutrofil limfosit termasuk kategori tinggi.
GAMBARAN STATUS KONTROL ASMA DAN KUALITAS HIDUP ANAK DENGAN ASMA DI RSUP PROF. DR. I.G.N.G NGOERAH DENPASAR DAN RSUD WANGAYA DENPASAR TAHUN 2020-2021 Nurliandari, Nia; Witarini, Komang Ayu; Mayangsari, Ayu Setyorini Mestika; Pratiwi, I Gusti Ayu Putu Eka
E-Jurnal Medika Udayana Vol 12 No 12 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i12.P03

Abstract

Asthma is a chronic and emergency disease in children. Uncontrolled asthma in children can affect the quality of life of children and even lead to death. Bali is the province with the third highest prevalence of asthma after the Special Region of Yogyakarta and East Kalimantan. However, data regarding the description of asthma control status and quality of life of children with asthma in Bali, especially in Denpasar, are still limited. Therefore, the authors want to know the overview of asthma control status and quality of life of children with asthma at Prof. Dr. I.G.N.G Ngoerah Hospital Denpasar and Wangaya Hospital Denpasar in 2020-2021. The design of this research is descriptive observational with a cross-sectional approach. After the approval of the constitutional ethics committee, all children aged 6-11 years with asthma at the Outpatient and Inpatient Respirology Pediatric Clinic Prof. Dr. I.G.N.G Ngoerah Hospital Denpasar and Wangaya Hospital Denpasar in 2020-2021 which is recorded in a complete medical record and has approval for participation in the study by parents/guardians (n=32) will be given a questionnaire containing the child and parent’s biodata, Childhood Asthma Control Test (C-ACT) to assess asthma control status, and Pediatric Quality of Life (PedsQL) to assess children's quality of life through an electronic form. Based on asthma control status, the results showed that 27 children (84.4%) had fully controlled asthma control status and 5 children (15.6%) had partially controlled asthma control status. In controlled asthma control status, all children were male. The majority of children (3 children) have poor nutritional status and some (2 children) have obese nutritional status. All children have a family history of asthma. Most of the children's parents have the latest education in college (3 children), senior high school (1 child), and elementary school (1 child). All parents of children have jobs and most of them (3 parents of children) have salaries above the minimum wage. Based on the quality of life, there were 4 children (12.5%) with a disturbed quality of life and 28 (87.5%) children with an undisturbed quality of life. In terms of quality of life, there were 2 children, male and female, respectively. The majority of these children had good nutritional status (2 children) and did not have a family history of asthma (3 children). The parents of the 2 children have the last education in elementary school, while the other 2 parents have the last education in college. All of the children's parents have jobs and the majority (3 parents of children) have salaries above the minimum wage. Further research is needed with a larger sample size and should be carried out prospectively so that the data obtained is more complete.
Korelasi antara Pediatric Symptom Checklist-17 (PSC-17) dan Pediatric Quality Of Life Inventory (PedsQL) pada Anak Sekolah Dasar Setiyawan, I Made Karma; Saputra, I Made Yullyantara; Sindhughosa, Wega Upendra; Apsari, Ni Luh Sri; Sinardja, Siska Permanasari; Mayangsari, Ayu Setyorini Mestika; Witarini, Komang Ayu
E-Jurnal Medika Udayana Vol 13 No 9 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i09.P04

Abstract

Background : Identification of psychosocial problems and quality of life of school-aged children should be routinely applied in child developmental health-related practices. The main concerns in measuring the quality of life of children with psychosocial disorders are mainly related to language development, cognitive development and the type of disorder. This has led to the identification of developmental disorders in school-aged children requiring specific tools (PSC-17 score and PedsQL score) designed for pediatric patients. The similarities or differences obtained based on these measurement tools will depend on the precise formulation of the questions as well as the assessment of the situation of the individual being evaluated. Methods : An analytic observational study using a cross-sectional design involve three elementary schools in the Jimbaran area, Badung, Bali. The study was conducted at Udayana University Hospital in July 2022. The scores used in this study were self-reported PedsQL scores and PSC-17 scores obtained based on interviews with children. The correlation between the evaluation results using the PSC-17 and PedsQL questionnaires was evaluated using the Spearman correlation test. Results : Amongst 189 children, median age was 11 years (range 11–13 years). There was a significant correlation between PSC-17 scores and PedsQL scores (r= -0.59; p<0.001). Subgroup analysis on PSC-17 aspect subscales and PedsQL dimensions found significantly varying negative correlations. Conclusion : This study found a moderate negative correlation between PSC-17 scores and PedsQL scores, varying correlations strength between each aspect/dimension of each score. Keywords: children, quality of life, PedsQL, psychosocial, PSC-17.
CORRELATION BETWEEN DURATION AND SITTING POSITION WITH THE INCIDENCE OF LOWER BACK PAIN DURING ONLINE LEARNING Ahyana, Ahyana; Nurhidayah, Irfanita; Amalia, Riski; Kamal, Anda
E-Jurnal Medika Udayana Vol 12 No 11 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i11.P03

Abstract

Low back pain is a musculoskeletal disorder that is very common and has an impact on socioeconomic, individual, family, and community losses. Low back pain is choking between the 12th thoracic rib and the bottom of the gluteal fold, with or without pain radiating down the leg. Since the coronavirus disease 2019 (COVID-19) outbreak hit Indonesia, learning that has been carried out in schools and university has become online learning where learning uses laptops or cell phones with internet facilities and in a prolonged sitting position. The condition of sitting for a long time is the most common posture performed during online learning, so it can cause discomfort and pain in the lower back. This study aimed to determine the correlation between duration and sitting position with the incidence of back pain during online learning. This study used a descriptive correlational method with a cross-sectional design. The sample in this study was 203 students of the Faculty of Nursing at Syiah Kuala University. The data collection technique used a valid and reliable Sitting Position Duration (DPD) questionnaire with a Cronbach's Alpha value of 0.729 and the Nordic Body Map (NBM) questionnaire to see low back pain. This study showed no significant relationship between sitting duration and back pain (p-value = 0.625), sitting duration, and buttock pain (p-value = 0.616). A significant relationship exists between sitting position and back pain (p-value = 0.002) and sitting position and buttock pain (p-value = 0.001). It was concluded that an unergonomic sitting position for a long time could cause low back pain

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