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Padjadjaran Journal of Dentistry
Published by Universitas Padjadjaran
ISSN : 19790201     EISSN : 25496212     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Padjadjaran Journal of Dentistry or known as PJD, is an English-language scientific periodicals published by the Faculty of Dentistry Universitas Padjadjaran thrice a year on every March, July and November. The submission process of manuscript is open throughout the year. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted with acceptance for publication. Designed as a medium of information and scientific knowledge, Padjadjaran Journal of Dentistry publishes numerous research articles, in the area of Oral Biology, Dental Material Science and Technology, Oral and Maxillofacial Surgery, Pedodontics, Dental Public Health and Community Dentistry, Conservative Dentistry, Periodontics, Prosthodontics, Orthodontics, Oral Medicine, Dental Radiology, as well as with their development through interdisciplinary and multidisciplinary approach. Initially published as Padjadjaran Journal of Dentistry (PJD) magazine ISSN 1979-0201(print) on 2007 in form of printed issues. In 2017, the magazine had its online published version under the same with ISSN 2549-6212 (online) in accordance with the policy of LIPI. Padjadjaran Journal of Dentistry has been using Open Journal System requiring all writers to register in advance before they are allowed to upload the manuscript they write online. Afterwards, the editors, peer reviewers, and writers can monitor the manuscript processing. Several other changes are informed in the Journal History.
Arjuna Subject : -
Articles 1,002 Documents
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Molecular docking analysis between anti-apoptosis EGFR and four coumarins, and four carbazole alkaloids: in silico study Afriza, Dhona; Suriyah, Wastuti Hidayati; Ichwan, Solachuddin Jauhari Arief; Knights, Joe
Padjadjaran Journal of Dentistry Vol 36, No 1 (2024): March 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no1.52467

Abstract

Introduction: The anti-apoptotic protein EGFR is typically overexpressed in the majority of head and neck squamous cell carcinomas (HNSCC) and has been targeted for genetic therapy. The Clausena excavata plant is an evergreen shrub that has been widely used for various disease therapies, including cancer. Coumarin and carbazole alkaloids are the plant's primary active ingredients. This study aims to determine the molecular interaction between EGFR and several coumarins (clauslactone E, dentatin, nordentatin, clausenidin) and carbazole alkaloids (7- hydroxyheptaphylline, clausine E, 2,7 - dimethoxy - 9H - carbazole - 3- carbaldehyde,and 2,7 – dimethoxy - 9H - carbazole – 3-carboxylic acid). Methods: This research was carried out in silico using the molecular docking method. Molecular docking analysis was performed using AutoDock Vina, AutoDockTools 1.5.6., Pymol, and Discovery Studio Biovia 2021. The three-dimensional structure of the EGFR protein was retrieved from the RCSB Protein Data Bank. Ligands were obtained from the PubChem Compound Database. The comparison ligand was doxorubicin. Molecular docking results were analyzed based on binding affinity, amino acid interactions, visualization of docking results, and Lipinski's rule of five. Results: All of the investigated ligands with the EGFR receptor had strong binding affinity (-6.8 and -8.3 kcal/mol), almost the same as the comparison ligand (-8.2 kcal/mol). Each interaction also produced a different number of amino acid residues. Conclusion: These four coumarin compounds and four carbazole alkaloid compounds are considered potential EGFR inhibitors and anticancer candidates.KeywordMolecular docking, anticancer, oncogene protein, natural compunds
The potential of rambutan honey toothpaste in reducing the dental plaque index: a quasi Experimental study Yuslianti, Euis Reni; Ningrum, Anindya Sekar Ayu; Endrowahyudi, Hartanto
Padjadjaran Journal of Dentistry Vol 35, No 3 (2023): November 2023
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no3.50310

Abstract

ABSTRACTIntroduction: The accumulation of dental plaque is a common cause of dental and oral health problems such as caries and periodontitis, therefore it is necessary to control plaque. Brushing is the most effective way to control plaque. Currently, there are various toothpastes used by the people, one of which is herbal toothpaste. One of the herbal toothpastes that has an antibacterial potential is rambutan honey toothpaste. The purpose of this study was to analyze the effectiveness of rambutan honey toothpaste in reducing the dental plaque index. Methods: this research was Quasi Experimental design research with a pre-test post-test control group design. The twenty samples were divided into three treatment groups, namely the group that brushed teeth with base toothpaste, rambutan honey toothpaste, and aquadest. All samples were asked to brush their teeth using base toothpaste, rambutan honey toothpaste, and aquadest twice, after using toothpaste for one day, the plaque index was measured by the Silness and Loe method. Data were analyzed using Kruskal-Wallis and post hoc Mann-Whitney tests (p<0.05). Results: There was a significant difference between the plaque index score before and after using rambutan honey toothpaste with a p value=0.005 (p≤0.05). The results also showed the effect of brushing teeth with base toothpaste, rambutan honey toothpaste, and aquadest on plaque index with a value of p=0.005 (p≤0.05). The results showed that there was no significant difference in dental plaque index between base toothpaste and rambutan honey toothpaste with a p value=0.583. Conclusion: Rambutan honey toothpaste has a potential in reducing the dental plaque index.Keywords: plaque index, rambutan honey, toothpaste
Differences in the tooth impaction characteristics between males and females nonsyndromic cleft lip and palate patients: a cross-sectional study Andreas, Monica; Laviana, Avi; Mardiati, Endah; Sayuti, Elih; Noviaranny, Indah Yuri
Padjadjaran Journal of Dentistry Vol 36, No 2 (2024): July 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no2.54341

Abstract

ABSTRACTIntroduction: Nonsyndromic cleft lip and palate (nsCLP) refers to an abnormal gap in the upper lip and/or palate, without the presence of additional developmental abnormalities. The risk of tooth impaction in nsCLP-patients is greater than in patients without nsCLP. This research aimed to analyze the differences in the tooth impaction characteristics between males and females nsCLP-patients.  Methods: Type of research is cross-sectional study. CLP by observing 64 panoramic radiographs as population, consisting of 28 males and 36 females with the chronological age of over 7 years. The sampling technique used was purposive sampling of tooth impaction and the number of samples are 14. Univariate analysis was performed to examine the data on tooth impaction characteristics. Bivariate analysis was performed to compare the tooth impaction characteristics between males and females. Results: The proportion of tooth impaction in males (28.57%) was greater than in females (16.67%). Tooth impaction generally affects one tooth. Maxillary permanent canines (64.71%) were the most frequently affected teeth. Most of the impacted teeth were located above the cemento-enamel junction, but less than half the length of the adjacent tooth root with unfavorable angulation<650 to the intercondylar line. There were no significant differences in the tooth impaction characteristics, including proportion (p-value=0.5557), number (p-value=0.0644), position (p-value=0.8273), and angulation (p-value=0.8248), between males and females nsCLP-patients. However, there was a significant difference in the type of impacted teeth (p-value=0.0000) between the two genders. Conclusions: There were no differences in the tooth impaction characteristics, including the proportion, number, position, and angulation, except for the type of impacted teeth, between males and females nsCLP-patients. A small proportion of nsCLP-patients was found to have one impacted tooth, with maxillary permanent canines being the most frequently affected teeth. Impacted teeth were commonly located in favorable positions, but with unfavorable angulation.KEYWORDSTooth impaction, nonsyndromic cleft lip and palate, panoramic radiography
Management of Ankyloglossia with different severity: a case series in dental surgery Christianto, Stephanus; Priyanto, Winarno; Sjamsudin, Endang
Padjadjaran Journal of Dentistry Vol 36, No 1 (2024): March 2024
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no1.53574

Abstract

Introduction: The lingual frenulum is an important oral structure that plays an important role in the act of suction, speech, and feeding. Ankyloglossia (tongue tie) is a congenital anomaly that results when lingual frenulum is too short and adhere to tip of tongue, limiting the tongue movement. This case report aimed to explain management of Ankyloglossia with different severity. Case Report: This case report reported three cases of ankyloglossia with different ages and complaints of difficulty in feeding and speech. The patients were treated for lingual frenectomy procedure under general anesthesia using one haemostats method. The haemostats were used to clamp the upper aspect of frenulum which might have been helpful to guide the incision close to ventral surface of tongue. Care had to be taken not to injure the submandibular ducts when making incision at lower part of tongue. The result after 1 week of surgery: the wound was completely healed. Conclusion: Ankyloglossia will impair the function of suction, speech and feeding that affecting a considerable number of infants and children. It is important that accurate information and guidance are given to parents with regard to the indications and potential benefit of tongue tie revision. These case series offer guidelines which can be used by general and pediatric dentist for examination, diagnosis and treatment of ankyloglossia in different severity.KeywordAnkyloglossia, congenital, lingual frenulum
Antibacterial activity of nano-hydroxyapatite paste of snakehead fish bone against S. mutans: an in vitro study Dewi, Nurdiana; Rahmadella, Afifah; Hatta, Isnur; Apriasari, Maharani Laillyza; Putri, Deby Kania Tri
Padjadjaran Journal of Dentistry Vol 36, No 1 (2024): March 2024
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no1.51018

Abstract

ABSTRACTIntroduction: Caries is the most common oral disease found in society. The prevalence of caries in South Kalimantan is as high as 46.9% in 2018. S.mutans is the causative microorganism in the  initial occurrence of caries. Strategy that can be used to prevent caries is by adding nano-hydroxyapatite to the tooth paste. Nano-hydroxyapatite can be obtained from Snakehead (Channa striata) fish bone.  Snakehead is a kind of fish that is abundant in Banjarmasin.  This study aimed to analyze antibacterial activity of the nano-hydroxyapatite paste from snakehead (Channa striata) fish bone against S.mutans bacteria. Methods: The study consisted of 5 treatment groups: negative control (basic formula), positive control (casein phosphopeptide-amorphous calcium phosphate or CPP-ACP) and three treatment groups (nano-hydroxyapatite paste concentration of 10, 20 and 30%. The paste was made in the formulation of F1, F2, and F3. The antibacterial activity test by measuring MIC and MBC were performed using dilution method. Results: MIC of nano-hydroxyapatite paste was at a concentration of 10% with an average value of the difference absorbance of -0.468. MIC values in the concentration of 10%, 15%, 20% positive and negative control groups had a significant difference. MBC of nano-hydroxyapatite paste was at concentration of 15%. Concentration of 10% and the negative control group showed a significant difference, while concentration of 15% and 20% groups did not show a significant difference. Conclusion: Nano-hydroxyapatite paste from Snakehead fish bone has antibacterial activity in inhibiting and eliminating mutated S.mutans bacteria. The most effective concentration of antibacterial nano-hydroxyapatite paste to prevent caries was 10%. At this concentration, nano-hydroxyapatite can inhibit the growth of S.mutans without killing the bacteria.KEYWORDS fish bone, nano-hydroxyapatite, snakehead, S.mutans
Comparison of distribution and frequency of impacted teeth before and during COVID-19 pandemic in dental hospital: a descriptive study Syafin, Haura; Reksoprodjo, Muhammad Ramaditto; Julia, Vera; Heriasti, Maudina Dwi; Ariawan, Dwi; Sulistyani, Lilies Dwi; Utomo, Yudy Ardilla; Ratman, Muhammad Farid
Padjadjaran Journal of Dentistry Vol 35, No 3 (2023): November 2023
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no3.50127

Abstract

ABSTRACTIntroduction: The occurrence of the COVID-19 pandemic may affect the prevalence of patients with complaints of impacted teeth in dental hospital Faculty of Dentistry University of Indonesia (FKG UI), and there is no recent research on the distribution and frequency of impacted teeth based on age, gender, and teeth type in this hospital during the COVID-19 pandemic. This study aims to determine the distribution and frequency of impacted teeth during the COVID-19 pandemic in dental hospitals. Methods: A descriptive study uses the secondary data on impacted teeth patient's medical records. Utilizing purposive sampling, we selected participants for the research by carefully examining medical records to identify individuals that had undergone impacted tooth removal. The study used secondary data from the medical records of oral surgery patients at dental hospital FKG UI from June 2019 to June 2021, including complete patient identity, clinical diagnosis, and panoramic radiograph of the impacted teeth in June 2019 to June 2021. Diagnosis was determined through screening of medical records and panoramic radiographs. Data were analyzed using the statistical analysis software (SPSS version 21, IBM Corp.) Results: From 3,225 medical records of oral surgery patients at dental hospital FKG UI before and during COVID-19 pandemic, A total of 1292 patients were included in the study and 1496 impacted teeth cases were found. The frequency of impacted teeth cases before the pandemic was 825 (55.1%) cases; there were 671 (44.9%) cases during the pandemic. Conclusion: COVID-19 has caused a decrease in the distribution and frequency of impacted teeth cases, mostly in the middle aged patients, while more female as compared to male. The most common occurrence was in the third molars and the lowest was in the second molar tooth. Keyword : tooth, impacted, COVID-19, retrospective studies, wisdom tooth
The effect of Pangium edule (kluwek) extract on the discoloration of resin composite microhybrids: an experimental laboratory Ibrahim, Irsan; Alawiyah, Tuti; Amelia, Herlin
Padjadjaran Journal of Dentistry Vol 36, No 2 (2024): July 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no2.54437

Abstract

ABSTRACTIntroduction: Composite resin is a restoration material that is often used because it has high aesthetic value. Hybrid composite resins are currently one of the most popular materials for aesthetic restoration. This is due to several advantages, including low shrinkage, low abrasion, and better surface smoothness than small-particle composite resins. Pangium edule is a spice used in a variety of dishes, including rawon, brongkos vegetables, and konro soup. Apart from its function as a flavouring, Pangium edule also makes food browner in color. This Kluwekstudy aims to analyze the effect of Pangium edule extract on the discoloration of resin composite microhybrids. Methods: Type of research is experimental laboratory use of 24 microfiller hybrid resin composite specimens with a diameter of 6 mm and a thickness of 2 mm were used. The 24 specimens were divided into three groups based on their soaking time: 1 day, 3 days and 5 days, to see any color changes. Each treatment time group consisted of 8 specimens soaked in the Pangium edule solution. The Vita Easy Shade tool was used to verify color change measurements. Analyzed data using the one-way Anova test Results: The one-way Anova test findings revealed a significant difference (p=0.000) in the color change of composite resin that was soaked in Pangium edule solution for one, three, and five days. Conclusion: The change in the color of microhybrid composite resin soaked in Pangium edule solution for 1 day, 3 days and 5 days can cause color changes, especially in the hue value.KEYWORDSdiscoloration, resin composite microhybrid, Pangium edule
Correlation of xerostomia in methadone therapy program patient with oral health related quality of life using oral health impact profile-14: a cross-sectional study Theresia, Tiarma Talenta; Fitri, Andrian Nova; Sudhana, Widijanto; Astoeti, Tri Erri
Padjadjaran Journal of Dentistry Vol 36, No 1 (2024): March 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol36no1.50783

Abstract

ABSTRACTIntroduction: Methadone Therapy Program (MTP) patients receive treatment with antidepressants which work as salivary flow inhibitors that promote xerostomia. Decreased salivary secretion affects several essential aspects of life quality, such as speaking, chewing, and food swallowing. It also increases the risk of rampant caries. This study aimed to analyze correlation of xerostomia in MTP with Oral Health Related Quality of Life (OHRQoL) using the Oral Health Impact Profile (OHI-P 14). Methods: Type of research was a cross-sectional design, this study's main independent variable was xerostomia, the dependent variable was OHRQoL, and the confounders were age, gender, education, occupation, caries status, oral hygiene status, history of HIV infection, smoking habits, and alcohol consumption. Data analysis used logistic regression to see the risk factors that influence OHRQoL. Results: Xerostomia is a subjective dry mouth complaint asked through a questionnaire. Of the 26 respondents, 13 (50%) reported dry mouth. Salivary Flow Rate (SFR) measurement showed the result of 13 people was <0.3 (hyposalivation). OHrQOL was measured using OHI-P 14 questionnaire, 12 respondents had good OHRQoL (score > 6.5) and 13 respondents had bad (score ≤6.5). Risk factors associated with OHRQoL were age (p=0.08) and duration of methadone consumption (p=0.06). Conclusion: There is no correlation between xerostomia in MTP with Oral Health Related Quality of Life (OHRQoL) using the Oral Health Impact Profile (OHI-P 14). Future research should involve several hospitals that carry out MTP so that the research results are more valid.KEYWORDSmethadone, oral health related quality of life, OHrQOL, OHIP-14,  xerostomia
Trends of number of patient visits, demographic, and patient diagnosis at a dental hospital during the COVID-19 pandemic: a descriptive study Siboro, Sarah Velita; Suryanti, Netty; Putri, Fidya Meditia
Padjadjaran Journal of Dentistry Vol 35, No 3 (2023): November 2023
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no3.48492

Abstract

ABSTRACTIntroduction: The long-standing COVID-19 pandemic had resulted in the implementation of service restrictions and the emergence of patients' fear of coming to health facilities, which could have caused changes in patient visit trends. The aim was to determine trends in the number of visits, demographic characteristics and patient diagnoses during the COVID-19 pandemic. Method: the descriptive and population research used secondary data from medical records of new visiting patients and existing patients at the general dental clinic, pavilion clinic, and emergency ward at the Universitas Padjadjaran Dental Hospital (RSGM UNPAD) from April 2019 to March 2021. Sample for number of patient visits before and during the pandemic, the total sampling was 12,714 and the characteristics and diagnosis of patients during the pandemic were 3,625 medical records, while non-probability sampling technique with purposive sampling was used. Univariate analysis used frequency distribution, line charts, bar charts. Result: The number of patient visits at RSGM UNPAD during the pandemic decreased by around 60% (from 9,089 to 3,625 visits) compared to before the pandemic. The patient demographics during the pandemic at RSGM and at its three polyclinics were relatively the same: adults (26-45 years), female, domiciled in the city of Bandung, private employees, Moslem, Sundanese, unmarried, and past patient status.The most common diagnosis at RSGM was pulpitis 914 (61%); in general dental polyclinic was pulpitis 751 (33%); in the pavilion clinic was malocclusion 428 (32%) and in the emergency ward was pulpitis, necrosis of pulp and impacted each 4 (16%). Conclusion: During the COVID-19 pandemic, patient visits to the dental hospital decreased more than half, the demographic characteristics of the three polyclinics were relatively the same and the most common patient diagnosis was pulpitis.KEYWORDS : Demographics; dental hospital; oral diagnosis; the COVID-19 pandemic; trend of patient visits
The effect of the pseudostem extract of ambon banana on the number of lymphocytes and fibroblasts in gingivitis : an experimental study andriani, Ika; Medawati, Ana; Lestra, Citra; Salsabila, Millati; Khairunnisa, Putri Nabilla
Padjadjaran Journal of Dentistry Vol 35, No 3 (2023): November 2023
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol35no3.49051

Abstract

ABSTRACTIntroduction: Gingivitis is an inflammation of the soft tissue that supports the teeth. Chemical treatment in the form of mouthwash, such as chlorhexidine, is often recommended. However, long-term use of chlorhexidine mouthwash will cause side effects, such as allergies, irritation of the oral cavity, and discoloration of the oral mucosa and teeth. Therefore, natural alternative materials containing flavonoids, saponins, and tannins that can cure gingivitis are needed. These ingredients are found in the pseudo stem of the Ambon banana. This research aims to analyze the effect of applying the pseudostem extract of Ambon banana on the number of lymphocytes and fibroblasts in treating gingivitis. Methods: This study was an in vivo laboratory experimental study with a post-test control group. The study used 45 Sprague Dawley rats which were divided into 3 groups, namely the positive control group (chlorhexidine gel), negative control (gel base), and treatment (Ambon Banana pseudostem extract gel). The gingiva on the mandibular incisor of the rat was ligated, then the gel was applied to the gingiva. Decapitation of rats was carried out on days 1, 3, 5, 7, and 9, and then made histological preparations with HE. Staining and observations were later made. Data analyzed using Kruskal-Wallis test. Results: The results showed that Ambon banana false stem extract gel reduced the number of lymphocyte cells with a significant difference of p=0.016 (p<0.05) and increased fibroblasts at p=0.85 (p>0.05). Conclusion: The pseudostem extract gel of Ambon banana reduced the number of lymphocyte cells and increased fibroblasts in gingivitis treatment.Keywords: fibroblasts, gingivitis, lymphocytes, pseudostem of ambon banana

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