Article Per Year (5 Year)
p-Index From 2021 - 2026
2.249
P-Index
This Author published in this journals
All Journal Jurnal Anestesiologi Indonesia MEDISAINS Jurnal Pendidikan Kimia FKIP Universitas Halu Oleo Smart Medical Journal Walisongo Journal of Chemistry Adimas : Jurnal Pengabdian Kepada Masyarakat Majalah Kesehatan Pharmamedika Majalah Sainstekes Jurnal Pengabdian Al-Ikhlas Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Jurnal Sains Agro Makara Journal of Science Eduvest - Journal of Universal Studies Jurnal Katalisator Journal of Entrepreneurship and Community Innovations Current Biomedicine Jurnal Ilmiah Kesehatan Sandi Husada (JIKSH)
Juniarti
Magister Sains Biomedis, Sekolah Pascasarjana, Universitas YARSI, Jakarta
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

Published : 28 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 28 Documents
Search

 1   2   3 
ISOLATION AND STRUCTURAL ELUCIDATION OF FLAVONOID FROM BOESENBERGIA PANDURATA RHIZOME Moch Abdussalam; Juniarti; Indah Permata Yuda
Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Vol. 8 No. 1 (2026): Literasi Artikel Penelitian Kimia
Publisher : Program Studi Kimia, Fakultas MIPA, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/jc.v8i1.6518

Abstract

Temu Kunci (Boesenbergia pandurata) rhizome constitutes a botanical resource long harnessed for ethnomedicinal applications among localized populations. To validate its long-standing traditional application, this investigation aimed to characterize the bioactive chemical profile of the Boesenbergia pandurata rhizome. The dried, pulverized rhizome was initially subjected to maceration for crude extraction of secondary metabolites, followed by a meticulous purification sequence. Vacuum Liquid Chromatography (VLC) was first employed for bulk separation, and subsequent Radial Chromatography refined the flavonoid-rich fractions to yield a pure isolate. The structure of this isolate was then conclusively resolved using advanced 1H-NMR and 13C-NMR spectroscopy, which unambiguously identified the primary compound as pinostrobin.
Fitokimia Dan Uji Antioksidan Ekstrak Jarak Tintir (Jatropha Multifida Moch Abdussalam; Indah Permata Yuda; J Juniarti
Jurnal Sains Agro Vol 11, No 1 (2026): Jurnal Sains Agro
Publisher : Universitas Muara Bungo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36355/jsa.v11i1.1871

Abstract

Jarak tintir (Jatropha multifida) merupakan tanaman obat tradisional yang berpotensi sebagai sumber antioksidan alami, menawarkan alternatif penting dari keanekaragaman plasma nutfah tropis. Penelitian ini bertujuan untuk mengkaji kandungan fitokimia dan aktivitas antioksidan dari ekstrak daun Jatropha multifida. Ekstraksi dilakukan menggunakan beberapa jenis pelarut, kemudian dilakukan uji fitokimia dan uji aktivitas antioksidan. Hasil analisis fitokimia menunjukkan adanya berbagai senyawa metabolit sekunder yang berperan dalam aktivitas biologis. Ekstrak dengan pelarut polar cenderung memiliki aktivitas antioksidan lebih tinggi dibandingkan pelarut lain. Temuan ini mengindikasikan bahwa Jatropha multifida berpotensi dikembangkan sebagai agen antioksidan alami, membuka jalur baru diversifikasi produk non-pangan di luar skema pertanian konvensional. Penelitian ini memberi dasar ilmiah untuk pemanfaatan lebih lanjut dalam bidang kesehatan.
Prognostic Value of IL-6 for Mortality in ICU Patients with Sepsis: A Systematic Review and Meta-Analysis Maulitia Neny Yusuprihastuti; Juniarti Juniarti; Linda Weni; Diniwati Mukhtar; Hari Hendriarto Satoto
JAI (Jurnal Anestesiologi Indonesia) Vol 18, No 2 (2026): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.82097

Abstract

Objectives: To evaluate the prognostic value of interleukin-6 (IL-6) for mortality in intensive care unit (ICU) patients with sepsis.Study design: This study was conducted as a systematic review and meta-analysis of observational studies. Study quality was assessed using the Quality in Prognosis Studies (QUIPS) tool, and adjusted hazard ratios (HRs) were pooled using a random-effects model.Data sources: A comprehensive literature search was performed in PubMed, Scopus, Cochrane Library, and ScienceDirect for studies published up to March 2026. Reference lists of relevant articles were also screened to identify additional eligible studies.Data synthesis: Eighteen studies were included in the qualitative synthesis, and six studies were included in the meta-analysis. Elevated IL-6 levels were consistently higher in non-survivors across studies. The pooled analysis demonstrated that increased IL-6 levels were significantly associated with higher mortality risk (HR = 1.39, 95% CI 1.14–1.70; p = 0.001), with moderate heterogeneity (I² = 70%), likely reflecting differences in study populations, measurement timing, and study design. Sensitivity analysis excluding one large multicenter study reduced heterogeneity (I² = 0%) while maintaining statistical significance (HR = 1.29, 95% CI 1.13–1.47; p < 0.001), confirming the robustness of the findings.Conclusions: Elevated IL-6 is significantly associated with increased mortality in ICU patients with sepsis. Despite heterogeneity, the findings are consistent and support the role of IL-6 as a prognostic biomarker, particularly when integrated with other clinical and laboratory parameters.Registration: The protocol for this systematic review was prospectively registered in PROSPERO.
Potential Role of Moringa oleifera in Reducing Inflammation and Oxidative Stress in Sepsis-Related Reperfusion Injury Maulitia Neny Yusuprihastuti; Juniarti Juniarti; Linda Weni; Diniwati Muchtar; Hari Hendriarto Satoto
Smart Medical Journal Vol 9, No 1 (2026): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v9i1.116642

Abstract

Introduction: Sepsis-associated ischemia–reperfusion injury amplifies oxidative stress and inflammation, driving organ dysfunction. Moringa oleifera contains flavonoids, isothiocyanates (e.g., MIC-1) and other phytochemicals with reported antioxidant and anti-inflammatory activities that may mitigate these processesMethods: This study was conducted as a narrative literature review. Relevant articles were searched in PubMed, Google Scholar, and Scopus using keywords related to sepsis, reperfusion injury, oxidative stress, inflammation, and Moringa oleifera. Articles published between 2016 and 2026, available as open-access full texts in English or Indonesian, were included. Selected studies were screened by title, abstract, and full text, and the findings were analyzed descriptively.Results: Moringa oleifera contains a wide range of bioactive compounds, including phenolic acids, flavonoids, fatty acids, and isothiocyanates, which are widely recognized for their antioxidant and anti-inflammatory properties. These compounds may help reduce oxidative stress primarily by scavenging reactive oxygen species (ROS), lowering malondialdehyde (MDA) levels, and enhancing the activity of antioxidant enzymes such as superoxide dismutase and glutathione peroxidaseConclusion: moringa oleifera shows reproducible antioxidant and anti-inflammatory effects in vitro and in animal models of sepsis-related reperfusion injury, supporting its potential as an adjunctive therapy to reduce reperfusion-mediated organ damage. Well-designed clinical trials and standardized extract/dose protocols are required to establish efficacy and safety in humans.
ISOLATION OF ANTIOXIDANT COMPOUNDS FROM KEBIUL (CAESALPINIA BONDUC L) SEED SHELLS Mohd Abdus salam; Indah Permata Yuda; Juniarti
JURNAL KATALISATOR Vol. 11 No. 1 (2026): Jurnal Katalisator, Volume 11 No 1 April 2026
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/yyx6jb26

Abstract

Caesalpinia bonduc L. is a medicinal plant widely distributed in tropical and subtropical regions and has long been utilized in traditional medicine for the treatment of various ailments. Its seeds are recognized as a rich source of bioactive secondary metabolites, particularly flavonoids, phenolic compounds, terpenoids, and diterpenes, which have been associated with antioxidant, anti-inflammatory, antimicrobial, and antidiabetic activities. However, studies focusing on the isolation, purification, and characterization of individual bioactive compounds from C. bonduc seeds remain limited. Therefore, this study aimed to isolate, purify, identify, and evaluate the antioxidant activity of bioactive compounds obtained from C. bonduc L. seeds. Bioactive compounds were isolated from the seed extract through successive extraction, chromatographic separation, and purification procedures. The purified compound was subsequently characterized by phytochemical identification and evaluated for its free radical scavenging activity using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The isolated compound was identified as a flavonoid based on its chemical characteristics. Antioxidant evaluation demonstrated that the isolated flavonoid exhibited potent free radical scavenging activity, with a half-maximal inhibitory concentration (IC₅₀) of 3.31 ± 0.12 µg/mL, indicating a very strong antioxidant capacity. The findings demonstrate that C. bonduc seeds constitute a valuable source of naturally occurring antioxidant compounds and support their traditional medicinal use.  
Effect of jatropha-placenta-cmc formulation on second-degree burn wound healing in rats: Fibroblast growth factor expression Mellyna Mellyna; Juniarti Juniarti; Nunung Ainur Rahmah; Restu Syamsul Hadi; Nabila Pyrenina Thamrin
Jurnal Ilmiah Kesehatan Sandi Husada Vol. 15 No. 2 (2026): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : LPPM Politeknik Sandi Karsa, South Sulawesi, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiksh.v15i2.380

Abstract

Introduction: Second-degree burns require effective topical therapy to accelerate tissue regeneration and reduce complications. Current treatments remain limited by side effects and suboptimal regenerative outcomes. This study aimed to evaluate the effectiveness of a combination gel of Jatropha multifida L. latex, placenta extract, and carboxymethyl chitosan (JM–P–CMC) on burn wound healing by assessing fibroblast growth factor (FGF) expression, fibroblast count, and collagen density. Research Methodology: A post-test-only controlled experimental design was conducted using 18 male Sprague-Dawley rats, allocated into 6 groups. Standardised second-degree burns (1×1 cm) were induced and treated for 15 days. Histological and immunohistochemical analyses were performed at days 5, 10, and 15. Data were analysed using the Kruskal–Wallis and Mann–Whitney tests (α=0.05), with effect sizes expressed as median differences (%) and 95% confidence intervals (CI). Results: The JM–P–CMC group demonstrated significantly higher FGF expression compared to saline (Day 15 median: 75 vs 33; =42%; p=0.0015; 95% CI: 18–60). Fibroblast counts were also significantly increased (median: 55 vs 17; =38%; p=0.0001; 95% CI: 20–64). Collagen density was markedly higher in the intervention group (58.83% vs 21.70%; p<0.01). A strong positive correlation was observed between fibroblast count and collagen density on day 10, whereas FGF showed an inverse regulatory relationship with collagen during the remodelling phase. Conclusion: The JM–P–CMC gel significantly enhances burn wound healing through modulation of FGF expression, fibroblast proliferation, and collagen deposition. This formulation represents a promising, safe, and cost-effective alternative for topical burn management and supports the integration of bioactive-based therapies into clinical and nursing practice.
Circular Economy and Economic Empowerment through Livestock Waste Composting in Mandalamekar Village Hilma Suyana; Juniarti Juniarti; Imelda Sari; Khalisha Putri Mario
Journal of Entrepreneurship and Community Innovations Vol 5 No 1 (2026): August 2026
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/jeci.v5i1.527

Abstract

Mandalamekar Village, Cimenyan District, Bandung Regency, faces unmanaged livestock manure, odour, environmental risks, and continued dependence on externally purchased chemical fertilisers. This community service program aimed to convert livestock waste into marketable compost while strengthening local production capacity and establishing a village-based circular enterprise. A Participatory Action Research approach was implemented through participatory assessment, technical training, assisted production, standard operating procedure development, an agronomic demonstration plot, packaging and branding, cost calculation, and market-access development. Thirty members of the livestock and farmer groups participated in the intervention. Evaluation combined pre-test and post-test measurement, production monitoring, physical compost-maturity indicators, qualitative observation, and a simple cost and sensitivity analysis. The program produced 100 kg of mature compost in the first production cycle, established a production SOP, prepared five initial sale-ready sacks, and generated a gross margin of 50.18% at a selling price of IDR 25,000 per kg and production cost of IDR 12,455 per kg. The results indicate that integrating technical capacity building with downstream business development can strengthen local waste valorisation, create supplementary income opportunities, and operationalise circular economy principles at village level.
A Study on the Effectiveness of Jatropha multifida L. Latex–CMC (Carboxymethyl Chitosan) in the In Vivo Healing of Second-Degree Burns (Expression of FGF, Fibroblasts, and Collagen) Merry Desna; Juniarti Juniarti; Nunung Ainur Rahmah; Risdwati Djohan; Nenden Sobarna Prabu
Eduvest - Journal of Universal Studies Vol. 6 No. 9 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i9.53368

Abstract

Burn injuries remain a significant health concern because delayed healing can increase the risk of infection, scarring, disability, and treatment-related costs. This study aimed to evaluate the effectiveness of a gel formulation combining 15% Jatropha multifida L. latex and 3% carboxymethyl chitosan (CMC) in the healing of second-degree burns. Male Sprague–Dawley rats were assigned to six groups: saline, gel base, J. multifida latex, 3% CMC, Bioplacenton, and J. multifida–CMC gel. Second-degree burns were induced using a heated metal probe, and treatments were administered according to group allocation. Skin tissue samples were collected on days 5, 10, and 15. Fibroblast growth factor (FGF) expression was examined using immunohistochemical analysis, fibroblast numbers were quantified using hematoxylin–eosin staining, and collagen density was evaluated using Masson’s trichrome staining. Data were analyzed using parametric or nonparametric statistical tests with a significance level of p < 0.05. The combined gel increased FGF expression, particularly on day 15, and produced significant differences in fibroblast numbers across all observation periods. Collagen density also improved significantly on days 10 and 15, indicating enhanced extracellular matrix formation and tissue remodeling. These effects may be attributed to the complementary bioactive properties of J. multifida latex and the moist, biocompatible environment provided by CMC. In conclusion, J. multifida–CMC gel demonstrated potential as an antibiotic-free therapeutic option for second-degree burn healing; however, further toxicity assessments and clinical studies are required to confirm its safety and efficacy.
Co-Authors Abdussalam, Moch Agustin, Rika Alivia Ahmad Aulia Jusuf Aryenti . Aryenti Aryenti Aryenti, Aryenti Delvi Osmeli Dinda, Salsabila Chyllia Diniwati Muchtar Diniwati Mukhtar Ferlianti, Rika Hans -Joachim Freisleben Hari Hendriarto Satoto Hari Hendriarto Satoto Hilma Suyana Idris, Muthoharoh Imelda Sari Indah Permata Yuda Indah Permata Yuda Indah Permata Yuda Indah Permata Yuda Indra Kusuma Indra Kusuma Indranita, Lusy Janah, Lulu Ah Khalisha Putri Mario Lilian Batubara Linda Weni Linda Weni Maulitia Neny Yusuprihastuti Maulitia Neny Yusuprihastuti Mellyna Mellyna Merry Desna Moch Abdussalam Moch Abdussalam Moch Abdussalam Mohamad Sadikin Mohd Abdus salam Nabila Pyrenina Thamrin Nazwirman Nazwirman Nazwirman Nazwirman Nazwirman Nazwirman Nazwirman Nazwirman Nenden Sobarna Prabu Nunung Ainur Rahmah Nunung Ainur Rahmah Osmeli, Delvi Patrisha, Milaviza Permata Yuda, Indah Poerwaningsih, Ernie Ernie Restu Syamsul Hadi Restu Syamsul Hadi Risdwati Djohan Susi Endrini Susmiarsih, Tripanjiasih Taufik Nasrullah, Taufik Yuda, Indah Permata Yuhemita . Yuhernita . Yuhernita Yuhernita Yuhernita, Yuhernita Yurika Sandra Zainal Zawir Simon