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All Journal JURNAL PROMOSI KESEHATAN INDONESIA Jurnal Kedokteran Diponegoro Medica Hospitalia Diponegoro International Medical Journal (DIMJ) Ophthalmologica Indonesiana Indonesian Journal of Pharmacology and Therapy
Nugroho, Trilaksana
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Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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The Characteristics of Eye Diseases at Merpati Eye Clinic Dr Kariadi Hospital Semarang in 2020-2022 Rahmi, Fifin Luthfia; Wildan, Arief; Maharani, Maharani; Prihatningtias, Riski; Nugroho, Trilaksana; Rikiandraswida, Zahira; Ryamizard, Rizal
Diponegoro International Medical Journal Vol 4, No 1 (2023): July 2023
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v4i1.17677

Abstract

Background: The COVID -19 pandemic that has occurred since 2020 has changed and affected all aspects of life. In health services, the pandemic has limited patients from coming to health facilities. Recording of ophthalmology cases in health facilities has an important role in providing information about eye health problems that often occur in the community to identify what are the main challenges faced in the field of eye care.Objective: This study aims to identify the characteristics of eye diseases at the Merpati Eye Polyclinic Dr Kariadi Hospital Semarang in 2020-2022.Methods: This study was a retrospective descriptive study. The clinical characteristic data (gender, age, diagnosis, and Clinic) are retrieved from the medical records of patients suffering from eye diseases who underwent treatment at the Merpati Eye Clinic, Dr. Kariadi Hospital Semarang and was diagnosed in 2020-2022. The data obtained were processed and analyzed using the google sheets program.Results: There were 2961 newly diagnosed patients with the 10 most diagnosed diseases are Refractive disorders (12,87%), Cataracts (11,21%), Glaucoma (10,40%), Diabetic Retinopathy (6,75%), Pseudophakia (5,30%), Papile Atrophy (5,10%), Retinal Vein Occlusion (4,22%), Corneal Ulcer (3,92%), Retinal Detachment (3,71%) and Uveitis (3,51%). Based on age category, the most patients were 51-60 years old (22,29%). Based on gender category, female gender (50,35%) is more than male (49,65%).Conclusion: Of all patients, the 10 most diagnosed diseases were Refractive Disorders, Cataracts, Glaucoma, Diabetic Retinopathy, Pseudophakia, Papillary Atrophy, Retinal Vein Occlusion, Corneal Ulcers, Retinal detachment and Uveitis.
Screening of Refractive Disorders and Eye Health Awareness: Knowledge, Attitudes, and Behaviors of Elementary School Children in Semarang Saubig, Arnila Novitasari; Nugroho, Trilaksana; Rahmi, Fifin Luthfia; Dharma, Andhika Guna
Diponegoro International Medical Journal Vol 6, No 1 (2025): July 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v6i1.23477

Abstract

Introduction: Refractive disorders are the leading cause of visual impairment. Uncorrected refractive errors in children can significantly impact their development, especially regarding education and psychosocial growth.Objective: This study aims to determine the prevalence of refractive disorders and to assess the knowledge, attitudes, and behaviors related to eye health among elementary school children at SemarangMethodology: This is a descriptive study involving 200 students from SDN Wonotingal Semarang as the sample. The study included eye examinations to identify refractive disorders in students and a questionnaire to collect data on their knowledge, attitudes, and behaviors regarding eye health. Data were collected through school-based eye screening and were analyzed using Microsoft Excel and SPSS version 26.Results: The prevalence of refractive disorders among children at SDN Wonotingal Semarang was 14%, with Astigmatism Myopia Compositus being the most common type of refractive disorder at 67.9%. Among the 28 children with refractive disorders, the majority were 11 years old (75%). Refractive disorders were more prevalent in females (64.29%) than males (35.71%). The questionnaire data revealed that a large number of children had poor knowledge about eye health (97.9%). However, most children exhibited good attitudes (79.5%) and behaviors (66.0%) regarding eye health.Conclusion: The prevalence of refractive disorders among children at SDN Wonotingal Semarang is 14%, with Astigmatism Myopia Compositus being the most common type. A significant number of children still have poor knowledge about eye health.
Sleep Quality and Screen Time as The Most Influential Factor of Computer Vision Syndrome Dhafira, Farhana; Prihatningtias, Riski; Nugroho, Trilaksana; Maharani, Maharani
Jurnal Promosi Kesehatan Indonesia Volume 18 No.2 Agustus 2023
Publisher : Master Program of Health Promotion Faculty of Public Health Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpki.18.2.73-78

Abstract

Background: Since the Covid-19 Pandemic hit Indonesia, college students have had many eye health complaints; one is Computer Vision Syndrome (CVS). Factors that can increase the risk of CVS are decreased sleep quality, high computer/laptop use duration, and a non-ergonomic position. This study aimed to prove the relationship between sleep quality, visibility, and screen time on the incidence of CVS in medical students of Diponegoro University.Method: This cross-sectional study, including 147 medical students was conducted using primary data from questionnaires of Wendy Strouse Watt, Thomas H Murphy, Hospitality Eye Care Center, and vsp.com to gain data on respondent identity, visibility, and screen time. Sleep quality data were taken from the PSQI and CVS data through the CVS-Q questionnaire. Chi-square, Mann-Whittney, and logistic regression of multivariate analysis were used to analyze the data.Results: From 147 subjects, 108 were CVS (73.5%), and 39 were Non-CVS (26.5%). Variables of sleep quality and screen time (total) showed a significant relationship with CVS, which had p-values of p=0.001 and p=0.009 (p<0.05). As for the visibility to CVS, there was no relationship with p=0.863. In the multivariate test, sleep quality (p=0.000; ExpB=4.342) and total screen time (p=0.006; ExpB=3.913) were the most influential variables. The results showed that Computer Vision Syndrome is ubiquitous among Diponegoro University's final-year medical students. Sleep quality and total screen time can increase the risk of CVS by four times. This study also shows that CVS still appears in the post-pandemic era.
The Level of Knowledge, Attitudes and Behavior Regarding Cataracts of The Elderly Around The Primary Care Center Semarang Jacob, Ni Made Helen Virginia; Nugroho, Trilaksana; Dharma, Andhika Guna
Majalah Oftalmologi Indonesia Vol 48 No 2 (2022): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v48i2.100482

Abstract

Introduction: Cataract is the major cause of reversible blindness and visual impairment in developing countries. It has been assumed that there is poor access to information related to the cause, prevention, and treatment of cataracts in developing countries. There is also a paucity of data on knowledge, attitude, and behavior toward cataracts in Semarang. Objective: To determine the Knowledge, Attitudes, and Behavior Regarding Cataracts of The Elderly around the Primary Care Center Semarang Method: A community-based cross-sectional study was conducted among 40 participants in November 2019. The study participants were selected by a simple random sampling method. Data were collected with a structured questionnaire by using face-to-face interviews. The data were entered into Microsoft Excel 2016 and analyzed using Statistical Package for Social Sciences (SPSS) version 25. The level of statistical significance was set at a p-value less than 0.05. The Socio-demographic factor as Gender, Age, Education, Occupation, and Income set as independent variable in this study. Result: There were 40 respondents, based on questionnaire data 52,50% of respondents had good knowledge, 85% had a good attitude, and 60% had poor behavior. The Education and Knowledge (p=0,001), Education and Behavior (p=0,004), Knowledge and Behavior (0.57749p>0,5, Gender, Education and Income (p>0,05), Education and Income (p>0,05)had positive significant on the variables. Conclusion: A Good approach strategy is needed to achieve to increase public Knowledge, Attitude, and Behavior like doing health promotion periodically and improving health care performance, and facilitate their availability in primary care.
Color Field Test Charts Vs HVFA In Detection Visual Field Defect Chronic Primary Glaucoma Tanoko, Ivana; Winarto, Winarto; Nugroho, Trilaksana; Prihatningtias, Riski; Rahmi, Fifin L
Majalah Oftalmologi Indonesia Vol 48 No 2 (2022): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v48i2.100663

Abstract

Introduction: Glaucoma is syndrome consist of glaucomatous optic neuropathy, destruction of retinal nerve fiber layer, and typical visual field defects. Color field test charts (CFTC) is a simple and generous instrument used to detect central and paracentral scotoma in neuro-ophthalmology patient. Diagnostic study will perform in this research to compare visual field defects, detecting in chronic primary glaucoma patient between CFTC and HVFA SITA 10-2 as gold standard. Methods: Seventy two eyes from 50 patients with chronic primary glaucoma were examined visual acuity, funduscopy, color blindness, HVFA SITA 10-2 and CFTC. The results CFTC and HVFA were read by 2 ophthalmologists, and kappa agreement was done. Analysis was done to get sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, positive and negative likelihood ratio (LR). Result: The sensitivity of CFTC was 87.93%, specificity 85.71%, PPV 96.22%, NPV 63.16%, accuracy 87.5%, positive LR 6.15 and negative LR 0.14 in detecting visual field defect chronic primary glaucoma patient compared to HVFA SITA 10-2. Area Under Curve (AUC) in this research was 0.86 (95% CI 0.751-0.985, p<0.001). Sensitivity, PPV, and accuracy was higher in MD >-12dB compared to <-12dB. There was strong correlation between it in location of defect (Cramer’s correlation; V=0.679, p<0.001), although the large of visual field defect was significantly different between 2 instruments (p<0.05). Conclusion: Color field test charts is comparable to HVFA SITA 10-2 in detecting visual field defect chronic primary glaucoma moderate and advance stage.
Hubungan Kepatuhan Memakai Kacamata dengan Progresivitas Miopia pada Mahasiswa FK UNDIP Kingwijati, Syahriza Naufal; Wildan, Arief; Dharma, Andhika Guna; Nugroho, Trilaksana
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/hzcq9x75

Abstract

Introduction Myopia is a refractive error that causes images of distant objects to be focused in front of the retina by the non-accommodating eye. Myopia is one of the most common visual disturbances in the world. It is believed that the use of spectacle can reduce the progressivity rate of myopia. Spectacle can help light fall on the retina and prevent axial elongation of the eye. This theory needs to be investigated further so that it can be used as a reference. This study aimed to know the correlation between compliance of spectacle wear and myopia progressivity rate in medical students of Diponegoro University (UNDIP). Methods This research was an observational analytical study with cross-sectional design on 54 subjects ranging from 18 to 22 years old. Data are primary data obtained from questionnaires and objective eye examinations using an autorefractometer. The research was conducted from October to November 2021. Data were analyzed using Spearman Rank test which p<0,05 was considered significant. Results The mean of compliance of spectacle wear and myopia progressivity rate in medical students of UNDIP are (1,57±0,108) and (0,259±0,515) dioptres respectively. The correlation between compliance of spectacle wear and myopia progressivity rate are p=0,082 and r=0,239. Conclusion There are no correlation between compliance of spectacle wear and myopia progressivity rate in medical students of UNDIP. Keywords : Compliance, Spectacle, Myopia progressivity rate, Student
CLINICAL CHARACTERISTICS, CAUSALITY, AND EVALUATION OF EYE LID LACERATION SURGERY IN KARIADI GENERAL HOSPITAL, SEMARANG Lazuardi, Nizar Arif; Nugroho, Trilaksana
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/qz3k2644

Abstract

Introduction and Objective: Eyelid lacerations appear to be understudied in terms of adequate epidemiological research among all injury sites. The aim of this study was to assess the etiological characteristics, and evaluation of eyelid laceration surgery in Kariadi General Hospital. Method: In a observational analytic study with retrospective design, 89 cases of isolated traumatic eyelid laceration were consecutively studied and its epidemiology, etiology and the surgery were evaluated. All patients who underwent lid surgery between March 2021 and March 2023 were included. The data is analyzed to determine the features and the connection between the resulting frequency and the variables that were collected. Result: This study enrolled 89 patients with 66 (74.2%) males and 23 (25.8%) females. The largest age group in this study was 16–50 years old, with 53 patients (59.6%). With respect to the regio of laceration, medial laceration regio was reported in 69 patients (77.5%), central laceration regio was reported in 8 patients (9%), and lateral laceration regio was reported in 12 patients (13.5%). Based on the grade, 68 patients (76.5%) had full-thickness lacerations, and 21 patients (23.6%) had lamellar lacerations. Conclusion: Male tend to have a higher incidence rate than female. The highest age range is among adolescents and young adults.
Inhibition of Caspase-3 Provides Neuroprotection for Retina Ganglion Cells againts NMDA-induced Exitotoxicity in Wistar Rats: Oral Presentation - Observational Study - Resident Widyarini, Andriati Nadhilah; Maharani; Rahmi, Fifin L; Nugroho, Trilaksana; Saubig, Arnila Novitasari; Istiadi, Hermawan
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/fs7v9v35

Abstract

Introduction & ObjectivesGlaucoma is a disorder characterized by the presence of optic neuropathy. Visual impairment inglaucoma is caused by retinal ganglion cell (RGC) apoptosis associated with N-methyl-D-aspartate(NMDA)-mediated excitotoxicity. Excitotoxicity causes an increase in calcium in cells as well asactivation of caspase-3. Glaucoma therapy is currently given to reduce intraocular pressure (IOP),but the damage is still progressing progressively. Hesperidin is known as a neuroprotector that cansuppress calpain overactivation in NMDA-treated retina, thereby reducing the upregulation of TNF-,an inflammatory cytokine, inhibiting calpain activation by suppressing oxidative stress, andattenuating caspase-3 activation. The aim of this study to proving the effect of oral Hesperidin on theexpression of caspase-3 Retinal Ganglion Cell in Wistar rats model of NMDA-induced glaucoma. MethodsExperimental research with post test design only randomized control trial Wistar rats with NMDAinduction were divided into 2 treatment and control groups. The treatment group was given oralHesperidin at a dose of 100mg/kg/day while the control group was given Na-CMC 182 mg/kg/day for3 weeks. Retinal caspase-3 expression was examined by immunohistochemical staining. Data werecollected and processed and then the Mann- Whitney test was performed. (significant p<0.05) ResultsThe mean percentage and intensity of RGC caspase-3 expression in the treatment group were 4.29 ±0.49 it was significantly lower than the control group 6.29 ± 0.95 (p value = 0.003). ConclusionHesperidin provides neuroprotection for RGC againts NMDA- induced exitotoxicity by inhibition ofcaspase-3.
NEUROPROTECTIVE ROLE OF VITAMIN D3 ON GANGLION CELL-INNER PLEXIFORM LAYER THICKNESS IN NMDA-INDUCED RETINAL EXCITOTOXICITY MODEL OF GLAUCOMA: (Experimental Study on Wistar Rats Glaucoma Model with N-Methyl-D-Aspartate induction) Margareth, Ezra; Nugroho, Trilaksana; Dharma, Andhika Guna; Rahmi, Fifin L; Maharani; Istiadi, Hermawan
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/6xrxsv34

Abstract

Introduction & ObjectivesRetinal ganglion cell (RGC) damage can affect the thinning of the GCC layers, which is the nervefiber layer, the ganglion cell layer and the inner plexiform layer. The loss of RGC and inner plexiformlayer (IPL) is strongly correlated with the loss of visual field defect. RGC and inner plexiform layerare potential targets to evaluate the progression of glaucoma. Glaucoma treatment not only focus onreducing IOP. Decreasing IOP according to the target pressure often can’t stop the process of RGCdamage and make it permanently and irreversible. Vitamin D3 is known as neuroprotector which hasthe ability to protect RGC and prevent layer thinning of GC-IPL in retina. The aim of this study is todetermine the effect of oral Vitamin D3 on the GC- IPL layer thickness in retinal of Wistar rats withNMDA-induced glaucoma model. MethodsGlaucoma Wistar rats were divided into 2 groups. The treatment group was given oral Vitamin D3 ata dose of 500 IU/kgBW/day for 10 weeks. GC-IPL layer thickness in retinal was examined byHematoxylin Eosin staining. Data were collected and processed then used with Independent T Test.(significant p<0.05) ResultsThe mean GC-IPL layer Thickness in the treatment group was 77,59 ± 15,15 ?m and 35,32 ± 4,04?m in the control group. There was a significant different between two group ( p = <0,001 ) ConclusionVitamin D3 has a neuroprotective effect on ganglion cell-inner plexiform layer Wistar rats in NMDAinducedexcitotoxicity model of glaucoma
EFFECT OF “PERMATA-KU” EXERCISE ON THE AMPLITUDE OF ACCOMMODATION AND COMPUTER VISION SYNDROME SCORE IN COMPUTER USERS Azkadina, Amira; Nugroho, Trilaksana; Astuti, Fatimah Dyah Nur; Reki, Winarto; Dharma, Andhika Guna
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/e07wgj60

Abstract

Background and Objective: Intense and long-term computer users are at risk of suffering health problems known as computer vision syndrome (CVS) which can have an impact on physical, mental, and economic health. One of the alternative therapies developed is "PERMATA-KU" exercise to reduce complaints related to CVS. The aim of the study was to reveal the effect of "PERMATA-KU" exercise on amplitude of accommodation (AA) and Computer Vision Syndrome scores on computer users. Method: The study of a quasi-experimental with pre-post control design was done. The research subjects were divided into the “PERMATA-KU” exercise group (21 people) and the control group (19 people) with treatment for 4 weeks. CVS scores were measured using the CVS-Questionnaire and monocular AA scores were measured using the push-up method using a Berrens ruler. Mann-Whitney difference test analysis was performed. Results: The exercise group experienced a significant increase in monocular AA value (p=0.010) while the control group experienced a significant decrease in AA (p=0.025). The mean delta of monocular AA values between groups was significantly different after the intervention (p=0.001). There was a significant difference in CVS scores between the postintervention groups (p=0.006) with the mean delta CVS scores between groups being significantly different (p=0.002). There was no correlation between AA scores and CVS scores (p=0.126). Conclusion: "PERMATA-KU" exercise for 4 weeks was shown to significantly increase the value of amplitude of accommodation and decrease CVS scores, but the increase in accommodation amplitude did not correlate with a decrease in CVS scores.
Co-Authors Amelia, Sesa Amira Azkadina Arief Wildan, Arief Astika Widy Utomo, Astika Widy Astuti, Fatimah Dyah Nur Bharadaksa, Mohammad Arya Lingga Cahyono, Maharani Catharina Suharti Charles Limantoro DEWI WULANSARI Dhafira, Farhana Dharma, Andhika Guna Donna Hermawati Fathur Nur Kholis Fifin L. Rahmi Fifin Luthfia Rahmi Fitriani, Rizky Hari Peni Julianti Haris, Nadia Husna Hermawan Istiadi Hery Djagat Purnomo HS, Heri-Nugroho Ignatius Riwanto, Ignatius Indah Fitria, Indah Ivana Tanoko Jacob, Ni Made Helen Virginia Kingwijati, Syahriza Naufal Maharani Maharani Maharani, Maharani Mahayu Dewi Ariani, Mahayu Dewi Margareth, Ezra Nafia, Nisa Khoirun Nizar Arif Lazuardi, Nizar Arif Nyoman Suci Widyastiti Pambudi Utomo, Gede Puspita Kusuma Dewi, Puspita Kusuma Rahmi, Fifin L Reki, Winarto Rikiandraswida, Zahira Riski Prihatningtias, Riski RR Mahayu Dewi Ariani Ryamizard, Rizal Sadasih, Wisnu Saubig, Arnila Novitasari Septian, Kevin Setyorini, Desti Putri Teguh Setiawan Widijanto, Utami Widyarini, Andriati Nadhilah Wijaya, Friska Winarto Winarto Yora Nindita