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All Journal Jurnal Biosains Pascasarjana Jurnal NERS Jurnal Teknologi Laboratorium Molecular and Cellular Biomedical Sciences (MCBS) Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Dharma Bakti NERSMID: Jurnal Keperwatan dan Kebidanan Jurnal Ilmu dan Teknologi Kesehatan Medica Hospitalia Journal of Pharmaceutical Care Anwar Medika Jurnal Pengabdian Kesehatan Medfarm: Jurnal Farmasi dan Kesehatan Indian Journal of Forensic Medicine & Toxicology Jurnal Olahraga Pendidikan Indonesia (JOPI) Calvaria Medical Journal KOPEMAS Sadewa: Jurnal Pengabdian Masyarakat

Nurdianto, Arif Rahman

STIKES Rumah Sakit Anwar Medika

Author-ID : 1220110

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Tingkat aktivitas fisik dan kualitas tidur masyarakat di Jawa Timur selama masa pandemi covid-19 Laily Mita Andriana; Kunjung Ashadi; Arif Rahman Nurdianto
Jurnal Olahraga Pendidikan Indonesia (JOPI) Vol. 1 No. 1 (2021): Jurnal Olahraga Pendidikan Indonesia (JOPI)
Publisher : Kementerian Pemuda dan Olahraga Republik Indonesia

Aktivitas olahraga yang dilakukan secara berkelanjutan dan bersifat jangka panjang serta kualitas tidur yang baik merupakan faktor terpenting untuk menjaga dan meningkatkan imunitas tubuh di masa pandemi Covid-19. Penelitian ini bertujuan untuk menganalisis tingkat aktivitas fisik dan kualitas tidur pada masyarakat selama masa pandemi covid-19. Metode yang digunakan adalah cross sectional design yang melibatkan sebanyak 384 responden yang telah mengisi kuesioner online yang dibagikan melalui google form. Instrumen penelitian yang digunakan adalah Global Physical Activity dan Pittsburgh Sleep Quality Index. Teknik analisis data yang digunakan persentase tingkat aktivitas fisik dan kualitas tidur. Hasil penelitian menunjukkan 62,3% masyarakat yang belum pernah menjadi pasien covid-19 memiliki tingkat aktivitas fisik pada kategori sedang dan 28,1% pada kategori berat. Sebanyak 37,1% memiliki kualitas tidur yang sangat baik dan 52,9% memiliki kualitas tidur yang cukup baik. Sedangkan pada pasien covid-19 100% memiliki tingkat aktivitas yang ringan dan 35,5% memiliki kualitas tidur yang cukup baik dan 34,7% cukup buruk. Pada masyarakat yang sudah sembuh dari covid-19 sebanyak 58,7% pada kategori aktivitas fisik sedang dan 57,7% memiliki kualitas tidur yang cukup baik

The Relationship of Hemoglobin, Interleukin-10 and Tumor Necrosis Factor Alpha Levels In Asymptomatic Malaria Patients in Trenggalek, Jawa Timur, Indonesia Arif Rahman Nurdianto; Heny Arwati; Yoes Prijatna Dachlan; Dyah Ayu Febiyanti
Molecular and Cellular Biomedical Sciences Vol 3, No 1 (2019)
Publisher : Cell and BioPharmaceutical Institute

Background: Malaria is still a universal health problem, especially in tropical countries because of high morbidity and mortality rates. Infection by Plasmodium falciparum and Plasmodium vivax could result in asymptomatic disease of malaria and be found in Trenggalek, Jawa Timur. Differences in pathogenesis among affected individuals are affected by many factors, and the immune system is one of them. Among substances involved in the malarial immunity is Tumor Necrosis Factor (TNF)-α and Interleukin (IL)-10, produced by the body's defense system as the reaction to the parasite. Therefore a study was designed to detect the level of TNF-α and IL-10 in asymptomatic malaria patients.Materials and Methods: A cross-sectional study was conducted. Thirty male asymptomatic malaria subjects, age 21 to 60 years were selected. Blood from each subject was collected and the levels of TNF-α and IL-10 were analyzed using enzyme-linked immunosorbent assay (ELISA) method. Significant values considered at p<0.05.Results: There was an increased level of TNF-α with the average of 218.760 pg/µL, and an increased level of IL-10 with an average of 257.574 pg/µL in asymptomatic malaria subjects. In normal person IL-10 level is 12.6 (8.5-16.7) pg/mL and the levels of TNF-α in normal person is 0-1.5 pg/mL because they are not produce. There was a positive correlation of TNF-α with IL-10 (r=0.332; p>0.05), and positive correlation between TNF-α and the rate of hemoglobin (r=0.002; p>0.05). IL-10 was correlated negatively with the rate of hemoglobin (r=-0.363; p<0.05).Conclusion: The results from this study conclude that TNF-α and IL-10 levels increase in asymptomatic malaria subjects.Keywords: asymptomatic malaria, TNF-α, IL-10, parasite, hemoglobin

Efektivitas Senam Diabetes Terhadap Kadar Glukosa Darah Pada Penderita Diabetes Melitus Di Puskesmas Trosobo, Sidoarjo Citra Amaniah Anhar; Elis Anita Farida; Farida Anwari; Acivrida Mega Charisma; Arif Rahman Nurdianto
Jurnal Pengabdian Kesehatan Vol 5, No 1 (2022): Jurnal Pengabdian Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/jpk.v5i1.189

Diabetes Melitus merupakan penyakit degeneratif yang memerlukan upaya penanganan yang tepat dan serius supaya tidak menjadi komplikasi. Kegiatan pengmas ini dilakukan dengan tujuan menganalisa efektivitas senam diabetes terhadapa kadar glukosa darah pada penderita Diabetes Melitus. Kegiatan ini dilakukan dari bulan februari hingga april 2021 di Puskesmas Trosobo, Sidoarjo. Variabel pada kegiatan ini adalah kadar Glukosa Darah sebelum senam (Pre Test) dan kadar Glukosa Darah setelah senam (Post Test) yang kemudian dianalisa dengan uji paired sample T – Test. Dari hasil analisa tersebut diperoleh dengan nilai t hitungnya 5,702 dengan p 0,000 atau 0,05, artinya senam diabetes efektif untuk menurunkan kadar Glukosa Darah pada penderita Diabetes Melitus di Puskesmas Trosobo, Sidoarjo.

PERAN KAPSAISIN PADA PENGHAMBATAN TERJADINYA KANKER Fery Setiawan; Arif Rahman Nurdianto; Rizal Fauzi Nurdianto; Heribertus Agustinus B Tena; Jenny Sunariani
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 10 No 2 (2021): MEDFARM: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v10i2.62

Kapsaisin (8-methyl-N-vanillyl-6-nonanenamide) adalah rasa pedas utama dalam batang cabai yang dikonsumsi secara umum. Fungsi utama kapsaisin adalah mengurangi rasa nyeri dan inflamasi neurogenik, selain itu juga memiliki efek anti-tumor. Reseptor kapsaisin dan substansi lain yang terkait dengan kapsaisin telah diidentifikasi dan dikloningkan. Reseptor ini adalah reseptor vaniloid subtipe 1 (VR-1), yang membentuk saluran kation non-selektif dalam membran plasma yang memediasi beberapa efek pleitropik. Kapsaisin dan substansi analog yang sejenis mempunyai efek anti-proliferatif dalam sel kanker manusia melalui induksi siklus sel fase G0/G1 sehingga proliferasi sel terhenti dan terjadi apoptosis pada beberapa sel yang mengalami transformasi. Kemampuan untuk menginduksi apoptosis merupakan aktivitas supresi plasma membran NADH-oksidoreduktase (PMOR), enzim yang mentransfer elektron dari sitoplasmik NADH melalui ko-enzim Q (ubikuinon) ke akseptor elektron eksternal, seperti oksigen. Selain menginduksi apoptosis melalui PMOR, kapsaisin juga menginduksi peningkatan p21, Bax, dan Poly ADP Ribose Polymerase (PARP). Mekanisme antitumor kapsaisin secara utama dengan melakukan stabilisasi dan aktivasi gen p53. Kapsaisin secara substansial memperpanjang siklus hidup p53 dan secara signifikan meningkatkan aktivitas transkripsional p53. PMOR diperkirakan terlibat dalam pengaturan pertumbuhan sel dan proliferasi dengan menjaga rasio NADH+/NADH yang sesuai dengan kebutuhan sel.

Description of complaints/clinical symptoms and examination results of the SARS-CoV-2 rapid test in Brata Medika Laboratory Clinic Pare - Kediri in February 2021 Acivrida Mega Charisma; Arif Rahman Nurdianto; Rizal Fauzi Nurdianto; Fery Setiawan; Heribertus Agustinus Tena
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.9734

SARS-CoV-2 antigen rapid test is one of the examinations widely used for early detection of Covid-19 infection. Rapid test is considered to have more advantages, is faster, and is cheaper than molecular PCR testing, and more accurate than rapid antibody tests. Its weakness is especially in detecting samples with small quantities of the virus. The study was conducted using a retrospective method. The data was taken from the patient's medical record of the SARS -CoV-2 antigen rapid swab test at Brata Medika Pare Clinical Laboratory for the period of February 2021. Data inclusion criteria including the examination, complete identity, results of anamnesis examination and rapid test examinations. Data were analyzed in a tabular form containing frequency and percentage. There were 18 (22.5%) patients with positive SARS-CoV-2antigen rapid swab test results, 16 (89%) with complaints/symptoms, and 2 (11%) without complaints/symptoms. Meanwhile, 62 (77.5%) were found with negative SARS-CoV-2 antigen rapid swab test results where 18 (29.0%) were patients with complaints/symptoms and 44 (71.0%) were patients without complaints/symptoms. The high percentage of negative SARS-CoV-2 antigen rapid swab test results in patients with complaints/symptoms (29.0%), it is recommended that a confirmatory examination with the molecular PCR test be carried out.

Pemulihan aktif lebih baik daripada pemulihan pasif untuk mengoptimalkan pemulihan tubuh pasca-latihan Laily Mita Andriana; Luh Putu Ratna Sundari; I Made Muliarta; Kunjung Ashadi; Arif Rahman Nurdianto
Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Vol 8 No 1 (2022): Jurnal SPORTIF: Jurnal Penelitian Pembelajaran
Publisher : Universitas Nusantara PGRI Kediri

One of the efforts to prevent the overreaching condition is by doing a recovery phase after exercise. The quality and quantity of recovery influence the effectiveness of recovery. The effectiveness of recovery can be observed by heart rate and body temperature after recovery. This study aims to compare active recovery and passive recovery after moderate-intensity continuous training on heart rate and body temperature. The research method used is quasi-experimental and uses a two-group pre and post-test design. Based on the Pocock formula, the research subjects used were 40 women aged 24 years to 35 years. The data collected include heart rate and body temperature. The data analysis techniques used were normality test, treatment effect test (paired sample t-test), and difference test (independent samples t-test). The results showed that active recovery was better than passive recovery to optimizing post-exercise heart rate (p<0.05). Active recovery was better than passive recovery in optimizing body temperature (p<0.05). It was concluded that active recovery after moderate-intensity continuous training was better than passive recovery to optimize post-exercise recovery and prevent overreaching.

COMPARISON OF ANTIMICROBIAL EFFICACY OF HONEY GEL AND CLOTRIMAZOLE CREAM IN THE TREATMENT OF VULVOVAGINAL CANDIDIASIS SYMPTOMS Arif Rahman Nurdianto; Heryanti Pusparisa; Hotimah Masdan Salim; Joko Sulistyo
Journal of Pharmaceutical Care Anwar Medika (J-PhAM) Vol 4 No 2 (2022): Journal of Pharmaceutical Care Anwar Medika
Publisher : STIKES Rumah Sakit Anwar Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36932/jpcam.v4i2.94

The available literature regarding the epidemiological or clinical features of vulvovaginal candidiasis (VVC) in most women will experience episodes of vulvovaginal candidiasis in their lifetime, 50% of whom will experience at least a second episode, and 5-10% of all women will experience recurrent vulvovaginal candidiasis (≥ 4 episode / 1 year). Vulvovaginal candidiasis is known as one of the most common yeast infections in women of reproductive age and is considered an important public health problem. In recent years, due to resistance to common antifungal drugs, the use of traditional antifungal medicines and herbal remedies has increased. Therefore this system aimed to investigate the effect of honey vaginal gel/ointment and to compare it with clotrimazole vaginal cream on symptoms of vulvovaginal candidiasis in patients. Vaginal clotrimazole is the drug of choice for the treatment of VVC. However, the increasing drug resistance to these microorganisms has led to greater interest in naturally occurring antifungal drugs. This systematic literature was conducted to compare vaginal honey ointment/gel and clotrimazole vaginal cream for the treatment of VVC.

Seroprevalensi Kasus Toxoplasmosis sebagai Infeksi Oportunistik pada Penderita HIV/ Acquired Immune Deficiency Syndrome (AIDS) Di Kabupaten Sidoarjo Andi Jayawardhana; Harnida, Hanna; Dewi Purwatiningsih; Heni Puspitasari; Mufasirin; Lucia Tri Suwanti; Arif Rahman Nurdianto
NERSMID : Jurnal Keperawatan dan Kebidanan Vol. 6 No. 1 (2023): Mei
Publisher :

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55173/nersmid.v6i1.133

Toxoplasma gondii is an obligate intracellular parasite that can cause toxoplasmosis infection. About 60% of the world's population has been infected. Toxoplasma cerebri is one of the most common opportunistic infections in the central nervous system of HIV patients. The disease is acute and chronic, with mild symptoms that are non-specific so it is difficult to distinguish from other diseases or is often asymptomatic. The incidence of Human Immunodeficiency Virus (HIV) occupies the highest place in Asia with high morbidity and mortality. Toxoplasma is ranked in the top 10 opportunistic diseases as a direct cause of morbidity and mortality, with variable symptoms and reactivation. The purpose of the study: to detect Toxoplasma gondii from blood samples of patients with HIV/Acquired Immune Deficiency Syndrome (AIDS). In immunocompromised conditions, especially HIV/AIDS, symptoms of severe complications will arise, one of which is toxsoplasma encephalitis (TE). The high rate of morbidity and mortality of TE in HIV/AIDS patients, around 30-40%, makes an accurate diagnosis important. Research Methods: The study design used was cross sectional to determine the level of IgG Toxoplasma Gondii antibodies in HIV patients and serologically. The research subjects were 30 individual subjects who were positive for HIV infection, of which 30 patients would be screened for the levels of IgG Toxoplasma Gondii antibodies and then see the correlation with lifestyle and food consumed. The achievement target of this research is to find out whether HIV patients have levels of IgG Toxoplasma Gondii antibodies through serological tests, so that appropriate therapy and education can be given for the treatment of toxoplasmosis, so that these results can be published scientifically in national journals, and become paper material in scientific meetings.

EDUKASI KESEHATAN BERBASIS KETANGGUHAN KELUARGA SEHAT DALAM MENGHADAPI PANDEMI COVID-19 BERBASIS TELEMEDICINE DAN MEDIA SOSIAL Martina Kurnia Rohmah; Farida Anwari; Arif Rahman Nurdianto
Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024 Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) 2021
Publisher : Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024

Show Abstract | Download Original | Original Source | Check in Google Scholar

Pandemi COVID-19 merupakan permasalah global yang saat ini sedang dihadapi oleh seluruh masyarakat dunia. Tingginya angka kasus baru dan kasus kematian akibat COVID-19 menjadi latar belakang perlunya pemahaman kepada masyarakat terkait dengan pemeliharaan kesehatan keluarga di masa COVID-19. Keluarga merupakan tatanan terkecil masyarakat yang terdiri dari anggota dengan berbagai usia dengan permasalahannya masing-masing. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan pemahaman kepada masyarakat Desa Trosobo dan Pertapaan tentang kesehatan keluarga di masa pandemi yang dilakukan secara virtual dengan memanfaatkan teknologi digital seperti telemedicine dan media sosial seperti youtube dan Whatsapp. Hasil kegiatan menunjukkan terdapat peningkatan pemahaman masyarakat tentang kesehatan keluarga di masa COVID-19 di kedua desa Trosobo dan Pertapaan mencapai 40 – 60%

ANALYSIS OF SEIZURES IN PATIENTS WITH MOTHERS HAVING A HISTORY OF Toxoplasma gondii INFECTION Nurdianto, Arif Rahman; Apsari, Francisca Cindy Meilia; Safira, Adelia; Hardiwan, Hanalda Wanda
Jurnal Biosains Pascasarjana Vol. 26 No. 2 (2024): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v26i2.2024.99-112

Toxoplasmosis is a disease caused by the parasite Toxoplasma gondii, with high prevalence in Southeast Asia, including Indonesia. This infection can cause brain damage and is associated with diseases such as epilepsy. This study aims to analyze the occurrence of seizures in patients whose mothers have a history of T. gondii infection. Toxoplasmosis during pregnancy can be transmitted to the fetus via the placenta, causing severe fetal tissue damage and potentially triggering neurological disorders like epilepsy. Pathophysiological mechanisms include increased blood-brain barrier permeability, excitotoxicity, and damage to glutamatergic receptors and mitochondria. In Indonesia, the prevalence of toxoplasmosis ranges from 40%-60%, with risk factors including contact with stray cats and consuming raw meat. This study utilizes a literature review method to investigate the relationship between maternal T. gondii infection and the incidence of epilepsy in offspring. The findings suggest that maternal T. gondii infection during pregnancy significantly increases the risk of epilepsy in offspring. Effective public health measures are crucial for raising prevention awareness and improving access to comprehensive prenatal care.

Co-Authors Acivrida Mega Charisma Acivrida Mega Charisma Amanda, Eviomitta Rizki Andi Jayawardhana Anis Byarwati Anwari, Farida Apsari, Francisca Cindy Meilia Aryati Aryati Citra Amaniah Anhar Devi, Anita Dewi Purwatiningsih Dimas Agung Trisliatanto Dyah Ayu Febiyanti Dyah Ayu Febiyanti Dyah Ayu Febiyanti Edy Mustofa Elis Anita Farida Fery Setiawan Fery Setiawan Hanna Harnida, Hanna Hardiwan, Hanalda Wanda Hari Purwoko Hendro Puspito Heni Puspitasari Heny Arwati Heribertus Agustinus B Tena Heribertus Agustinus Bilo Tena Heribertus Agustinus Tena Heryanti Pusparisa Himawan, Achmad Nurdin Hisbiyah, A’yunil Hisnindarsyah, Hisnindarsyah Hotimah Masdan Salim I MADE MULIARTA . Issaura Jenny Sunariani Joko Sulistyo Khoirun Nisyak Kunjung Ashadi Laily Mita Andriana Laily Mita Andriana Lucia Tri Suwanti, Lucia Tri Luh Putu Ratna Sundari Martina Kurnia Rohmah Mohammad Guritno Suryokusumo Mufasirin Negara, Yohanes Ardian Kapri Novantiano, Hendrian Novia Rahmawati Prajawanti, Kadeq Novita Pratiknya, Djatiwidodo Edi Puguh Widagdo Renny Nurul Faizah Rini, Anis Dwi Anita Rizal Fauzi Nurdianto Safira, Adelia Savirani, Rifda Sri Iswati Sunarjo Sunarjo Titut Harnanik Totok Indarto Widyasih Pritasari Yoes Prijatna Dachlan Yulianto Ade Prasetya, Yulianto Ade

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