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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Biomedical Journal of Indonesia Science and Technology Indonesia Jurnal SOLMA SRIWIJAYA JOURNAL OF MEDICINE Jurnal Kesehatan Abdimas Universal Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat: Humanity and Medicine Jurnal Pengabdian Dharma Wacana International Journal of Community Service Bioscientia Medicina : Journal of Biomedicine and Translational Research Conferences of Medical Sciences Dies Natalis Bioeksperimen JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Sabrina, Tia
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Coagulase-Negative Staphylococcus (CoNS) Susceptibility Pattern Towards Antibiotics in Infection Patients at RSUP Dr. Mohammad Hoesin Palembang Silvia Putri Sudirman; Tia Sabrina; Rizki Andini Nawawi; Rima Zanaria; Masayu Farah Diba
Biomedical Journal of Indonesia Vol. 10 No. 2 (2024): Vol 10, No 2, 2024
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v10i2.189

Abstract

Introduction. Coagulase Negative Staphylococcus (CoNS) is a bacterial species commonly causing infection in humans upon entrance into bloodstream. Antibiotics remain the therapeutic modality of choice in eradicating CoNS bacteria. Increasing incidence of antimicrobial resistance has made it difficult to administer the right treatment. In addition, CoNS susceptibility patterns differ between regions and with time. This study aimed to determine the susceptibility pattern of CoNS towards various antibiotics in infection patients at RSUP Dr. Mohammad Hoesin Palembang.  Methods. This study was a descriptive, observational study using the data from blood cultures of CoNS bacteria undergoing antimicrobial susceptibility test (AST) in the Clinical Microbiology Laboratory, and utilizing demographic and clinical data from the Medical Records Installation from July 1, 2021 to December 31, 2021. Results. There were 123 isolates from patient blood cultures which underwent AST. The most frequently identified bacterial species were Staphylococcus hominis ssp hominis, Staphylococcus epidermidis, Staphylococcus haemolyticus, and Staphylococcus saprophyticus. AST results showed that on average, CoNS were susceptible to tigecycline (100%), nitrofurantoin (98.4−100%), linezolid (86.1−100%), and vancomycin (80.6−100%). CoNS were most resistant to benzylpenicillin (100%), oxacillin (85.5−97.2%), and erythromycin (75−97.2%). Conclusion. CoNS were resistant towards several available antibiotics in RSUP Dr. Mohammad Hoesin Palembang.
Pemberdayaan kelompok ibu rumah tangga sebagai kader bijak antibiotik dalam upaya pengendalian resistensi antibiotik tingkat komunitas Farah Diba, Masayu; Amalia, Ella; Sabrina, Tia; Rivani, Erizka; Zanaria, Rima; Nawawi, Rizki Andini
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 5 No 2 (2024): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V5I2.140

Abstract

Infectious diseases are a threatening health problem in developing countries, including Indonesia. Diseases caused by bacterial infections can be overcome relatively easily after the discovery of various antibiotics. Uncontrolled use of antibiotics will trigger antibiotic resistance. With the incidence of antibiotic resistance, the potential of antibiotics will be reduced in treating infections and diseases in humans, animals and plants. Community service activities aim to provide knowledge to the community about antibiotics, how to use antibiotics wisely, and introduction to the concept of antibiotic resistance. The activities carried out were in the form of empowerment in the form of counseling for the community and assistance in the form of training for groups of prospective antibiotic wise cadres in the Siring Agung Village area. The results of this activity were obtained to increase the insight and knowledge of the community and health cadres about Antibiotic Wisdom, especially the use of antibiotics correctly, how to get them, how to follow up on antibiotic drug waste if it remains. In addition, the community and cadres also have the skills to wash hands properly and correctly using running water and soap independently to prevent transmission of infectious diseases. Furthermore, it is hoped that continuous service activities with similar themes at different layers or levels of society can be carried out in order for the community to know the importance of the principle of using antibiotics wisely so that the incidence of antibiotic drug resistance can be suppressed to increase.
Pemeriksaan Status Gizi Santri Sebagai Upaya Skrining dan Pencegahan Penyakit Infeksi Nawawi, Rizki Andini; Amalia, Ella; Sabrina, Tia; Rivani, Erizka; Zanaria, Rima; Diba, Masayu Farah; Usman, Doni; Al-Fayed, Muhammad Sadad; Zefianto, Zefianto; Ansyori, Achmad Rifky; Mansur, M. Syafi'i
Abdimas Universal Vol. 7 No. 1 (2025): April
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/abdimasuniversal.v7i1.2396

Abstract

Nutrition is a contributing factor in the maintenance of optimal immune system functions. Disturbances in nutritional status, such as malnutrition, would impact various structures, mediators, and processes in the immune system in responding to pathogenic infections, hence increasing vulnerability to infections. Adolescents are an age group often considered “healthy”, but screening in this age group proves important in reassuring optimal growth and development, which in turn will also impact the next generation. Pesantren is an Indonesian educational institution serving adolescents with a boarding school system, so it is of high importance for adolescent santri to know their own nutritional status in preventing infectious diseases. This community service event was held at Pesantren Thawalib Sriwijaya to inform about the importance of nutritional status in prevention of infectious diseases. The activities comprised of classical counseling and anthropometric measurement of participating santri. There were 42 participating santri attending Madrasah Tsanawiyah (MTs) and Madrasah Aliyah (MA) in this event, and plotting results showed most santri had normal nutritional status. However, nutritional status monitoring and awareness to infectious disease still needs to be kept up, as there are various other factors that may influence the spread of various infectious diseases.
Liposome Photosensitizer with Enzyme from Black Soybean Tempeh: Formula Optimization and In Vitro Thrombolytic Activity Evaluation Azzahra, Farah Daffa; Mulyani, Laida Neti; Sabrina, Tia; Fithri, Najma Annuria
Science and Technology Indonesia Vol. 10 No. 3 (2025): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.3.903-915

Abstract

Stroke and myocardial infarction contributed significantly as the leading causes of global mortality rate, both commonly caused by thrombosis. Black soybean tempeh (BSBT), a traditional Indonesian food fermented with Rhizopus oligosporus fungus is rich in proteolytic enzymes, with potential to be utilized for thrombosis related ailments. Herein, we report the first findings of BSBT enzymatic activity and its subsequent formulation into liposomal system as a thrombolytic. Additionally, we incorporated photosensitizer dyes into the liposomes, phycocyanin and fluoresecein, creating a photothermally active therapeutic delivery system. Liposomes containing BSBTwere formulated using soy lecithin and tween 80, whichwere then subjected to evaluations including size, PDI, zeta potential, morphological, and stability studies. Furthermore, we observed their photothermal efficiency and thrombolytic activity using whole blood clot in vitro model. BSBT crude and purified extract produced satisfactory enzymatic activity, stable at neutral pH (∼7) and maintained stable activity at temperatures of ∼60◦C. Liposome formulation was spherical with a particle size of 607.8 nm; PDI of 0.339; and zeta potential of -24.2 mV. BSBT crude extract and purified enzyme at a concentration of 100% gave 51.28 and 56.05% thrombolytic activity. Based on the test results obtained, the optimum formula of photosensitizer liposomes produced had high encapsulation efficiency, with photothermal efficiency of 57.66 and 44.23% for Lip-Flu and Lip-Phy respectively. The formulations with laser exposure generated good thrombolytic activity (∼55-56%) comparable with nattokinase. Based on these findings, liposomal delivery of BSBT enzymes can maintain proteolytic activity, providing the first insights for thrombolytic purposes of BSBT enzymes.
UPAYA PENCEGAHAN CACINGAN MELALUI EDUKASI DAN PRAKTIK KEBERSIHAN TANGAN DAN KUKU Handayani, Dwi; Dalilah, Dalilah; Sabrina, Tia; Prasasty, Gita Dwi; Susilawati, Susilawati; Naue, Dian Adhe Bianggo; Rahmadona, Risa; Fadilatunnisa, Nur
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2024): Volume 5 No 1 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i1.19541

Abstract

Infeksi cacingan masih menjadi masalah kesehatan di masyarakat namun seringkali diabaikan. Anak-anak usia sekolah dasar merupakan kelompok yang rentan mengalami infeksi ini. Salah satu faktor risiko terjadinya infeksi cacingan adalah kebersihan tangan dan kuku yang buruk akibat rendahnya pengetahuan dan kesadaran dalam mencuci tangan dan memelihara kebersihan kuku. Kegiatan ini bertujuan untuk memberikan edukasi kesehatan tentang cacingan dan praktik mencuci tangan enam langkah menurut WHO. Sasaran kegiatan ini adalah santri dan orangtua/wali santri Rumah Tahfidz Yatim Dhuafa Persaudaraan Muslimah Ilir Timur 2 (RTYD Salimah IT 2) yang berlokasi di Lorong Wiraguna, Kelurahan Kuto Batu, Kecamatan Ilir Timur 2, Kota Palembang. Edukasi dilakukan melalui beberapa metode yaitu pengisian kuesioner, pemeriksaan tinja, penyuluhan, dan praktik/peragaan cara mencuci tangan dan memotong kuku. Sebanyak 72 orang santri hadir dalam kegiatan dan mengisi kuesioner berisi pertanyaan mengenai cacingan, kebiasaan mencuci tangan, dan kebersihan kuku melalui observasi. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan dan psikomotor setelah diberikan edukasi terkait cacingan dan mencuci tangan. Pada pemeriksaan tinja ditemukan satu sampel yang positif cacing Ascaris lumbricoides. Peningkatan pemahaman mengenai bahaya cacingan diharapkan dapat menumbuhkan kesadaran dan kemandirian dalam pencegahan cacingan di keluarga dan masyarakat.
PENINGKATAN LITERASI KESEHATAN TENTANG PENYAKIT INFEKSI EMERGING DAN REEMERGING MELALUI SEMINAR DARING NASIONAL BAGI MAHASISWA DAN TENAGA KESEHATAN Rivani, Erizka; Amalia, Ella; Sabrina, Tia; Diba, Masayu Farah; Nawawi, Rizki Andini; Usman, Doni
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 9 No. 2 (2024): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v9i2.3403

Abstract

Penyakit infeksi emerging dan reemerging merupakan tantangan yang semakin signifikan dalam dunia kesehatan dalam beberapa tahun terakhir, terutama diakibatkan oleh makin berkembangnya globalisasi, urbanisasi, dan juga perkembangan teknologi di dunia. Berbagai penyakit infeksi baru bermunculan, dan penyakit infeksi yang telah dikenal sejak dahulu mengalami perubahan dari segi manifestasi klinik maupun tantangan dalam deteksi dan tata kelola. Hal ini membuat manajemen dari penyakit infeksi emerging dan reemerging menjadi unik dari segi kebaruan dan pengenalan penyakit. Pengabdian masyarakat dalam bentuk seminar bagi tenaga kesehatan diharapkan dapat meningkatkan kewaspadaan akan penyakit, termasuk bagi mahasiswa yang kelak akan menjadi bagian dari praktisi kesehatan. Seminar diadakan secara daring untuk memperluas cakupan acara sehingga dapat diikuti oleh peserta dengan berbagai latar belakang profesi kesehatan dari seluruh Indonesia. Materi yang disampaikan mencakup tantangan klinis dan manajemen penyakit serta peran laboratorium mikrobiologi klinik dalam deteksi dan pencegahan penyakit infeksi emerging dan reemerging. Terdapat peningkatan persentase jawaban benar dan nilai rerata dari post-test yang dikerjakan oleh peserta pasca paparan materi dibandingkan dengan pre-test. Adanya diskusi interaktif setelah paparan juga menunjukkan ketertarikan peserta akan materi yang disampaikan yang dinilai relevan untuk praktik klinis sehari-hari. Kegiatan pengabdian masyarakat ini memberikan dampak positif berupa peningkatan pemahaman dan motivasi peserta untuk menerapkan ilmu yang didapatkan dalam manajemen, deteksi, dan pencegahan penyakit infeksi emerging dan reemerging. Seminar daring diharapkan dan menjadi model edukasi berkelanjutan untuk meningkatkan kesiapsiagaan dalam menghadai perkembangan ilmu kesehatan secara global.
Cogon Grass Mesoporous Silica Nanoparticles Loaded with Uncaria gambir Extract and Photosensitizer for Photothermal Induced Anti-MRSA Activity: Formula Optimization and In Silico Exploration Mardiyanto; Sabrina, Tia; Alhafizh, M. Faris; Kota, Natacha Brigida; Ramadhona, Sheza Inayah; Valenia, Novella; Amrullah, M. Ammar; Zulda, Daghfal Rafataqwa; Marrisca, R.D. Nindi; Alisyahbana, Sutan Satya; Fadilah, Ade; Pratiwi, Aisyah; Fithri, Najma Annuria
Science and Technology Indonesia Vol. 11 No. 1 (2026): January
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2026.11.1.311-322

Abstract

In recent years antimicrobial resistance (AMR) has grown to become a massive concern for the global community due to their lack of successful prevention and low recovery rates. One of methods with high efficiency in reducing AMR is photodynamic and photothermal therapy (PDPT), due to their independency from chemical mechanism of antimicrobial efficacy. Mesoporous silica nanoparticle (MSN) is an excellent carrier for potential alternative for AMR including photosensitizers and natural based active ingredients. Herein, we explored the use of various sources as silica precursors as well as optimization based on method of fabrication and coating agent to stabilize and load the active ingredients. We additionally incorporated Uncaria gambir extract and phycocyanin to increase MSN antimicrobial effect and photosensitizing ability. Cogon grass-based MSN (CG-MSN) has yet to be explored extensively and in this research, we compared their characteristics to a more established precursors such as tetraethyl orthosilicate (TEOS) and sodium silicate. Based on the results obtained, cogon grass-based precursors produced the highest yield, with entrapment efficiency of Uncaria gambir and phycocyanin as high as 98%. Furthermore, CG-MSN produced one of the highest photothermal increase and adsorption rate comparable to that of TEOS. From in silico exploration Uncaria gambir contained Gambiriin and Roxburghin as two of the most active phytoconstituents that influenced its antimicrobial activity. Based on this research we were able to synthesize a new precursor of silica from natural based product, cogon grass, and incorporate it as carrier for phytocompounds in the management of AMR.
Karamunting Leaf Extract (Rhodomyrtus tomentosa (Aiton) Hassk.) as antibiofilm on Escherichia coli Sabrina, Tia; Mansur, Muhammad Syafi’i; Diba, Masayu Farah; Nawawi, Rizki Andini; Tamzil, Nia Savitri
Bioeksperimen: Jurnal Penelitian Biologi March 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v11i1.10815

Abstract

Escherichia coli is a bacterium that causes many serious infections such as digestive tract, urinary tract and bloodstream infections. One of the main challenges in treating this bacterial infection is the formation of biofilm, which increases bacterial resistance to antibiotics. As an alternative to overcome antibiotic resistance, karamunting has been identified as having antibacterial potential against Gram-negative bacteria, including E. coli. The active compounds in these leaves have been shown to inhibit bacterial growth and biofilm formation. This research describes the activity of karamunting leaf extract against the anti-biofilm E. coli. The thick karamunting leaf extract was then made into three variations of concentration, namely 125µg/mL, 250µg/mL and 500µg/mL. The parameter measured for the eradication test is the thickness of the biofilm which is read using the Elisa Reader 590nm. In this study, the eradication percentages for the three concentrations were obtained -92.15% at a concentration of 125 µg/mL, -187.24% at a concentration of 250 µg/mL and 52.78% at a concentration of 500 µg/mL. Karamunting leaf extract has activity as an antibiofilm against E. coli bacteria. Karamunting leaf extract with a concentration of 500 µg/mL is the Minimum Inhibitory Concentration (MIC) which is effective as an antibiofilm on E. coli.
Edukasi Daun Jambu Air sebagai Penanggulangan Penyakit Sindrom Metabolik di Desa Burai, Ogan Ilir Najma Annuria Fithri; Laida Neti Mulyani; Tia Sabrina; Siti Humairoh; M. Akram; Rumiyati Dwi Nindi Marrisca; Nadya Ramadhani Ikhsana
Jurnal SOLMA Vol. 15 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v15i1.20811

Abstract

Background: Desa Burai, Kecamatan Tanjung Batu, Kabupaten Ogan Ilir adalah kawasan wisata dengan produksi pertanian yang beragam, diantaranya adalah tanaman jambu air. Daun jambu air merupakan salah satu bahan alam yang memiliki sifat antioksidan tinggi, namun pemanfaatannya masih tergolong sedikit. Pengabdian ini bertujuan untuk meningkatkan pemanfaatan daun jambu air sebagai alternatif pengobatan sindrom metabolik. Metode: Upaya pencegahan ini dapat dilakukan secara tradisional menggunakan daun jambu air yang jarang dimanfaatkan dengan mengembangkannya menjadi teh dan saturasi untuk mendorong diversifikasi pemanfaatan tanaman herbal dan mengurangi efek samping yang ditimbulkan oleh penggunaan medikasi sintetik. Edukasi dan pelatihan dilakukan dengan metode pemberdayaan melalui pembinaan, pendampingan, dan pelatihan keterampilan membuat produk kaya antioksidan. Hasil: Dari hasil proses pembuatan teh, produk yang dihasilkan memiliki rasa yang tidak pahit, yang menandakan produk teh dan saturasi dapat dibuat dengan baik. Proses pendampingan masyarakat dalam pelatihan menunjukkan hasil yang positif berdasarkan nilai post test yang dilakukan setelah pelatihan. Kesimpulan: Masyarakat Desa Burai mampu menangkap pelatihan yang diberikan dan dapat menjelaskan manfaat minuman teh dan saturasi daun jambu air sebagai penanggulangan sindrom metabolik.
Education on Disease Risk Factors in Adapting New Habits to Prospective Hajj Pilgrims at KBHI Bisri-Pusri Palembang City Emma Novita Emma; Agita Diora Fitri; Tia Sabrina; Andyra Priandhana; Muhammad Musa; M.Taufik Wijaya
International Journal Of Community Service Vol. 1 No. 2 (2021): August 2021 (Indonesia - Malaysia)
Publisher : CV. Inara in Colaboration with www.stie-sampit.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijcs.v1i2.18

Abstract

Health istitha'ah is the health ability of the pilgrims physically and mentally with a measurable health assesment. It is essential for every citizen who will perform the hajj pilgrimage. The Indonesian Ministry of Health through the Non-Infectious Disease Integrated Service Post (Posbindu PTM) implements an early detection and prevention program for non-infectious diseases in sub-districts, schools or colleges, institutions or workplaces, and Hajj guidance groups (KBIH) especially for pilgrims. The department of public health and community medicine (IKM-IKK) of the Faculty of Medicine, Sriwijaya University perform an education on the detection of risk factors for non-infectious diseases and physical fitness assesment of prospective pilgrims in the context of community service activities at KBIH Bisri Palembang. Examinations were done on 40 prospective pilgrims using the Rockport test method. The results of the examination showed that the 24 pilgrims had moderate fitness level (60%). The blood pressure test results showed that 9 pilgrims had hypertension (22%) and the nutritional status test showed that 20 pilgrims were overweight and obese (38.5%). In addition, there is an assesment for prospective hajj pilgrims in order to understanding risk factors for non-infectious diseases. The result shows that there is a significant increase in understanding about non-infectious diseases in the adaptation of new habits.
Co-Authors Adnindya, Rulan Agita Diora Fitri Ahmad Ghiffari Ahmad, Qaedi Aisya Turridho Aisyah Pratiwi, Aisyah Al-Fayed, Muhammad Sadad Alhafizh, M. Faris Alisyahbana, Sutan Satya Amrullah, M. Ammar Andyra Priandhana Ansyori, Achmad Rifky Azzahra, Farah Daffa Dalilah Dalilah Desi Oktariana Desi Oktariana Dian Safriantini Diba, Masayu Farah Dwi Handayani Dwi Handayani Ella Amalia, Ella Erizka Rivani Erizka Rivani Evi Lusiana Evi Lusiana Fadilah, Ade Fadilatunnisa, Nur Farah Diba, Masayu Gita Dwi Prasasty Gita Dwi Prasasty Haerawati Idris Inda Astri Aryani Jayawarsa, A.A. Ketut Kamaluddin Kamaluddin Kamaluddin, MT Kota, Natacha Brigida Laida Neti Mulyani M. Akram M.Taufik Wijaya Mansur, M. Syafi'i Mansur, Muhammad Syafi’i Mardiyanto Marrisca, R.D. Nindi Masayu Farah Diba Masayu Farah Diba Miftahurrizqiyah MT Kamaluddin Muhammad Irsan Saleh Muhammad Musa Mulyani, Laida Neti Nadya Ramadhani Ikhsana Najma Annuria Fithri Najma Annuria Fithri, Najma Annuria NauE, Dian Adhe Bianggo Nawawi, Rizki Andini Nia Savitri Tamzil Novita, Emma Patricia, Venny Putra, Ramadhan Ananditia Rahmadona, Risa Ramadhona, Sheza Inayah Ricardo Simanjuntak Rima Zanaria Rima Zanaria Rima Zanaria Rivani, Erizka Rizki Andini Nawawi Rumiyati Dwi Nindi Marrisca Salni Salni Silvia Putri Sudirman Siti Humairoh Theodorus Theodorus Theodorus Tyas Hestiningsih Tyas Hestiningsih Usman, Doni Valenia, Novella Venny Patricia Zahrah Aliyah Qonitah Zanaria, Rima Zanaria, Rima Zefianto, Zefianto Zulda, Daghfal Rafataqwa