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All Journal JURNAL ILMIAH PLATAX POSITRON Jurnal Kimia Khatulistiwa BERKALA SAINSTEK Innofarm Jurnal Inovasi Pertanian Al-Kimia Jurnal Biologi Tropis Indonesian Journal of Pure and Applied Chemistry Jurnal Laut Khatulistiwa CHEESA: Chemical Engineering Research Articles Indonesian Journal of Chemical Analysis (IJCA) Jambura Journal of Chemistry Jurnal Darma Agung Equilibrium Journal of Chemical Engineering Lumbung Inovasi: Jurnal Pengabdian Kepada Masyarakat Center of Knowledge Bakti Budaya: Jurnal Pengabdian kepada Masyarakat Jurnal Riset Fisika Indonesia al Kimiya : Jurnal Ilmu Kimia dan Terapan
Aritonang, Anthoni Batahan
Department Of Chemistry, Tanjungpura University
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Journal : Al-Kimia

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Identifikasi Komponen Senyawa Organik dan Uji Aktivitas Antiinflamasi dari Fraksi Etil Asetat Daun Cabai Rawit (Capsicum frutescens L.) Uci Pradina; Ajuk Sapar; Warsidah Warsidah; Endah Sayekti; Anthoni Batahan Aritonang
Al-Kimia Vol 10 No 1 (2022): JUNI
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i1.20456

Abstract

Cayenne pepper was known to treat swelling of tissue cells and is thought to have anti-inflammatory activity. The aim study is to examine the anti-inflammatory activity of the ethyl acetate fraction of cayenne pepper and identify the components of organic compounds in the ethyl acetate fraction. The stages of this research include preparation, extraction, partitioning, phytochemical tests, anti-inflammatory activity tests using Human Red Blood Cells (HRBC), and identifying the components of organic compounds they contain. Among the three fractions obtained at the extraction stage, the ethyl acetate fraction had the best activity as an anti-inflammatory at a concentration of 1000 mg/L of 57.77%. The fractionation of the ethyl acetate fraction was carried out using Vaccum Liquid Chromatography (VLC), and four combined fractions were obtained. One of the combined fractions, code EA-4-5, with a weight of 0.188 grams, was analyzed using GC-MS and FTIR. The two main compounds obtained from the GC-MS analysis were dodecanoic acid (25.79%) and (-)-Loliolide (12.86%). The results of the FTIR interpretation of the EA-4-5 fraction showed absorption at a wave number of 3234.62 cm-1 (stretching vibration of the -OH functional group), 3088.03 cm-1 and 3028.24 cm-1 (stretching vibration of the functional group =CH), 2931.8 cm-1 and 2858.51 cm-1 (functional group strain vibration –CH), 1712.79 cm-1 (functional group strain vibration –C=O), and 1606.7 cm-1 (strain vibration functional group –C=C).
Co-Authors Adhitiyawarman, Adhitiyawarman Ajuk Sapar Andi Hairil Alimuddin Arfan Sindhu Tistomo Arie Antasari Kushadiwijayanto Ashari, Asri Mulya Asma, Al Asmawati Asmawati Aufa, Raisa Rasyada Ayu Hindayani Desi Listiani Eka Mardika Handayani Eka Pratiwi Endah Sayekti Ferdian, Rasyid Fransiska M Wenisda Harlia Harlia Harlia, H. Harry Budiman Helena, Shifa Ikha Safitri Ikha Safitri Imelda Hotmarisi Silalahi Jayuska, Afghani Jihandini, Syahwa Jumlia Kartika, Novi Kukuh Hernowo Kurniawan Alam Muza’ki Limbong, Winny Sunfriska M. Agus Wibowo Margareta Caroline Harunrasjid Maulida, Alifiani Maura, Gabriella Mega S Sofiana Mega Sari Juane Sofiana Melati Azizka Fajria Millenia Millenia Muhammad Agus Wibowo Muhammad Rizky Mulyana Munadi Munadi Nazarudin Nazarudin Nazarudin Nora Idiawati Nurdiansyah, Sy. Irwan Oman Zuas Oman Zuas Oman Zuas Prayitno, Dwi Imam Puji Ardiningsih Puji Ardiningsih Puji Ardiningsih Puji Ardiningsih Putri, Desy Harlina Putry Parwaty Resti Fartiwi Risko, Risko Rita Kurnia Apindiati Rita Kurnia Apindiati Robi, Robi Rozaqina, Nuri Rudiyansyah Rudiyansyah SALPRIMA YUDHA S Sari, Atna Sari, Heni Puspita Sitohang, Mikael Sitopu, Selli Dosriani Suparnawati Suparnawati Suparnawati Suparnawati Suparnawati, Suparnawati Suripto D Yuwono Syarif Irwan Nurdiansyah Uci Pradina Umi K Yaumidin Warsidah Warsidah Warsidah Warsidah Warsidah Warsidah Warsidah Warsidah Warsidah, Warsidah Wenisda, Fransiska Monita Winda Rahmalia Yaumidin, Umi K Yenny Lisbeth Siahaan Yuwono, Suripto D Zaharah, Titin Anita