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TULANG SESAMOID: STUDI LITERATUR TENTANG STRUKTUR, FUNGSI, dan SIGNIFIKANSI KLINISNYA Dewi, Nadia Purnama; Susanti, Melya; Vani, Ade Teti
Journal of Public Health Science Vol. 2 No. 1 (2025): Maret
Publisher : Yayasan Nuraini Ibrahim Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70248/jophs.v2i1.2309

Abstract

Penelitian ini bertujuan untuk mengevaluasi berbagai studi terkini mengenai potensi senyawa bioaktif dari tanaman sebagai agen antikanker melalui pendekatan molecular docking dan uji drug-likeness. Metode penelitian yang digunakan adalah Systematic Literature Review (SLR), dengan menelaah 15 artikel ilmiah yang diterbitkan antara tahun 2015 hingga 2025 dari database Google Scholar, ScienceDirect, dan PubMed. Artikel yang terpilih memuat data senyawa tanaman terhadap berbagai reseptor protein kanker seperti EGFR, ER-α, COX-2, dan p53, disertai dengan evaluasi energi ikatan (ΔG) dan karakteristik farmakokinetik senyawa. Hasil penelitian menunjukkan bahwa senyawa seperti kuersetin, kurkumin, kalkon, dan oxylaxanthone A memiliki afinitas ikatan kuat terhadap target protein kanker dengan nilai ΔG yang kompetitif terhadap ligan natif, serta profil kimiawi yang mendukung pengembangan sebagai kandidat obat. Simpulan, studi ini mengindikasikan bahwa pendekatan in silico berbasis molecular docking dan drug-likeness merupakan metode yang efektif dalam skrining awal senyawa antikanker dari tanaman, dan hasilnya perlu divalidasi lebih lanjut melalui uji biologis in vitro maupun in vivo untuk mendukung pengembangan fitofarmaka sebagai terapi kanker yang berkelanjutan.
Skrining Anemia dan Edukasi Pemanfaatan Probiotik pada Ibu Hamil Berisiko Stunting di Puskesmas Anak Air Kota Pad Amelia, Rinita; Rosmaini; Vani, Ade Teti; Efriza; Wahyuni, Sri; Suryanis, Ira
Abdika Sciena Vol 3 No 1 (2025): JURABDIKES Volume 3 No 1, Juni 2025
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/jurabdikes.v3i1.216

Abstract

Latar belakang: Anemia pada ibu hamil di Kota Padang merupakan masalah kesehatan yang serius, dengan prevalensi yang cukup tinggi. Penelitian terbaru menunjukkan bahwa faktor-faktor seperti status ekonomi rendah, kurangnya pengetahuan gizi, dan ketidakpatuhan dalam mengonsumsi suplemen zat besi berkontribusi terhadap tingginya angka anemia. Anemia pada kehamilan di Padang dapat menyebabkan komplikasi baik pada ibu maupun janin, sehingga memerlukan perhatian khusus melalui peningkatan intervensi nutrisi dan akses ke perawatan antenatal. Salah satu komplikasi Anemia dalam kehamilan adalah resiko kelahiran anak stunting. Tujuan: Program pengabdian masyarakat ini bertujuan untuk melakukan deteksi dini anemia pada Ibu hamil melalui serangkaian kegiatan edukasi dan skrining menggunakan alat Easy Touch. Kegiatan ini diharapkan dapat meningkatkan pengetahuan masyarakat khususnya ibu hamil tentang upaya pencegahan serta penanganan dini anemia melalui asupan probiotik susu kambing. Kegiatan dilakukan di Puskesmas Anak Air yang melibatkan kader-kader Posyandu dan bidan yang berada di wilayah kerja puskesmas anak air. Proses skrining meliputi pemeriksaan konsentrasi hemoglobin menggunakan alat Easy Touch, yang dilakukan dengan prosedur pengambilan sampel darah melalui tusuk jari dan analisis hasil secara cepat dan akurat. Selain itu, kegiatan penyuluhan mengenai pentingnya gizi seimbang, pemanfaatan probiotik dan pencegahan anemia dilaksanakan untuk meningkatkan kesadaran serta perubahan perilaku hidup sehat pada ibu hamil. Kesimpulan: Program pengabdian masyarakat tentang deteksi dini anemia pada ibu hamil ini merupakan langkah strategis dalam upaya pencegahan anemia pada ibu hamil yang beresiko terhadap lahirnya anak stunting. Keterlibatan berbagai stakeholder dan pendekatan intervensi yang komprehensif terbukti efektif dalam meningkatkan kesadaran dan mengidentifikasi ibu hamil yang berisiko, sehingga dapat dijadikan dasar bagi pengembangan program kesehatan yang lebih luas di masa mendatang.
PEMANFAATAN KURMA AJWA UNTUK KESEHATAN MASYARAKAT: EDUKASI BERBASIS BUKTI DI RT 03 RW 13 KELURAHAN GUNUNG PANGILUN, PADANG Abdullah, Dessy; Dewi, Nadia Purnama; Vani, Ade Teti
Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Vol. 3 No. 2 (2025): April
Publisher : CV. Alina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59407/jpki2.v3i2.2234

Abstract

Kurma Ajwa (Phoenix dactylifera L. var. Ajwa) dikenal sebagai salah satu varietas kurma dengan kandungan gizi tinggi dan manfaat kesehatan yang beragam. Di tengah meningkatnya kesadaran masyarakat akan pentingnya gaya hidup sehat, pemanfaatan pangan fungsional seperti kurma Ajwa menjadi relevan untuk dikembangkan. Kegiatan pengabdian ini bertujuan untuk memberikan edukasi kepada masyarakat RT 03 RW 13, Kelurahan Gunung Pangilun, Kota Padang, mengenai manfaat kurma Ajwa secara ilmiah dan aplikatif. Metode yang digunakan adalah penyuluhan interaktif dan pelatihan pembuatan olahan sehat berbahan dasar kurma Ajwa. Hasil kegiatan menunjukkan peningkatan pemahaman masyarakat terkait nilai kesehatan kurma Ajwa dan munculnya antusiasme untuk mengintegrasikannya dalam pola makan sehari-hari. Kegiatan ini diharapkan menjadi langkah awal dalam mendorong pemanfaatan pangan sunnah sebagai bagian dari gaya hidup sehat dan preventif.
EDUKASI DAMPAK NEGATIF PENGGUNAAN TAS PUNGGUNG DENGAN BEBAN BERLEBIH TERHADAP KESEHATAN VERTEBRAE PADA SISWA SMA 2 PADANG Vani, Ade Teti; Melya Susanti; Nadia Purnama Dewi; Rinita Amelia; Dessy Abdullah; Irwan Triansyah; Jefri Henky; Yanti Fitri Yasa; Muhammad Ivan
Nusantara Hasana Journal Vol. 4 No. 12 (2025): Nusantara Hasana Journal, May 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i12.1627

Abstract

Carrying a backpack that is excessively heavy can lead to negative effects, including pain in the shoulders, back, and waist. Additionally, it can cause postural changes due to alterations in the shape of the vertebrae. The goal of this Community Service Project (CSP) was to educate students at SMA 2 Padang about the proper use of backpacks, the appropriate weight for backpacks, and the negative effects of carrying overly heavy backpacks on the vertebrae. The method of CSP employed a pre-test and post-test method to measure knowledge retention. Throughout the activity, students received education and vertebral examinations. The key indicators for the CSP were the level of understanding gained regarding backpacks and the effects of excessive weight on vertebral health.The results of CSP indicated a significant increase in knowledge among the students at SMA 2 Padang, with all participants achieving perfect scores of 100 on the post-test. The vertebral examinations did not show any abnormalities, such as kyphosis or scoliosis. The conclusion of CSP successfully enhanced students' understanding of backpack weight and the potential negative impacts of carrying excessive weight on the vertebrae.
HISTOLOGI PENUAAN KULIT AKIBAT PHOTOAGING: ARTIKEL REVIEW Vani, Ade Teti; Rosmaini, Rosmaini; Nadia Purnama Dewi; Yuliza Birman; Melya Susanti; Rinita Amelia
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1646

Abstract

Photoaging is a complex skin aging process that results from prolonged exposure to ultraviolet (UV) light, leading to notable histological changes. This type of damage can affect both the epidermis and dermis layers of the skin. The purpose of this review article is to highlight and summarize the recent findings from the past five years concerning the histology associated with photoaging and the molecular mechanisms that contribute to this skin damage. The methodology employed involved a thorough literature review of articles published between 2020 and 2025. Journals were identified using targeted keywords, including "photoaging," "skin aging," "histology," and "actinic elastosis." The findings from this search are presented in a narrative format. The study found that UV exposure causes photoaging of the skin with damage to the epidermis and dermis. Photoaging causes structural and functional changes in the skin and causes gene mutations leading to skin carcinogenesis.
PENURUNAN KUALITAS TIDUR PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS BAITURRAHMAH PENDERITA RHINITIS ALERGIKA Triansyah, Irwan; Putri, Shyntia Peratami; Rosmaini; Vani, Ade Teti
Nusantara Hasana Journal Vol. 3 No. 8 (2024): Nusantara Hasana Journal, January 2024
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v3i8.1047

Abstract

Allergic rhinitis (RA) is an inflammatory disease of the nasal cavity that occurs after exposure to allergens mediated by Ig E, causing symptoms of repeated sneezing, rhinorrhea, itching and nasal congestion, and watery eyes. Congestion in the nose and sinus drainage will make it difficult for sufferers to sleep. Allergic rhinitis can affect the quality of sleep sufferers. The Type of this research is analytic observational study with cross sectional design. Population affordable of this research was all of the Medical Faculty students of Baiturrahmah University Class 2019 as many as 145 people with taking sample use technique simple random sampling. Data analysis used univariate analysis is presented in the form of distribution frequency and analysis bivariate use test spearman rho. There are 88 students or 60,7 % of students of the Faculty of Medicine, Baiturrahmah University Batch 2019 suffered from allergic rhinitis of all students, with the most allergic rhinitis were women as many as 30 students (36.6%). The most common clinical symptom was sneezing, which were 76 students (86.4%). There were 2 students with allergic rhinitis with good sleep quality (2.4%) and allergic rhinitis with bad quality of sleep obtained as many as 39 students (47.6%). Based on the analysis of the hypothesis test, the p-value was 0.000 (p>0.05), r=0,597, dan OR =30,469. There is relation between allergic rhinitis and quality of sleep of Medical Faculty students of Baiturrahmah University Class 2019. Conclusions: Medical Faculty students of Baiturrahmah University Class 2019 suffering from allergic rhinitis experience decrease sleep quality.
PENGENALAN ISI PIRINGKU DENGAN METODE PENDEKATAN SENI GAMBAR DI SMP YARI PADANG Vani, Ade Teti; Triansyah, Irwan; Dewi, Nadia Purnama; Abdullah, Dessy; Zulkarnaini, Aryaldi
Nusantara Hasana Journal Vol. 3 No. 8 (2024): Nusantara Hasana Journal, January 2024
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v3i8.1048

Abstract

Motivation/Background: The contents of Isi Piringku determine the nutritional status of adolescents. The wrong type, and the amount of food will cause malnutrition problems in adolescents. Introduction to the method of drawing art is effective for teenagers because drawing art includes learning to play. This method makes it easier to accept the concept of Fill My Plate. The purpose of the service activity is to provide knowledge about the contents of my plate as the first step in implementing a nutrition-conscious attitude for YARI Padang Junior High School teenagers. Method: The method of service is in the form of counseling and workshops. Counseling is carried out at the beginning and end of service. Workshops in the form of drawing art are given as core activities. Results: The results of dedication were obtained by only 5% of students who just learned about the contents of Isi Piringku. During the workshop 100% of students can analyze the contents of Isi Piringku and at the end of the service, 100% of students can analyze the contents of Isi Piringku. Conclusions: The conclusion of this devotion is that the art of drawing effectively increases the knowledge of the contents of my plate. Furthermore, the devotion of Isi Piringku can be continued with a food workshop Isi Piringku.
EDUKASI ISI PIRINGKU BERBASIS TEKNOLOGI DI NAGARI PADANG GANTIANG KABUPATEN SOLOK SELATAN Vani, Ade Teti; Irwan Triansyah; Nadia Purnama Dewi; Debie Anggraini; Yuri Haiga; Aryaldy Zulkarnaini; Yanti Fitri Yasa
Nusantara Hasana Journal Vol. 5 No. 7 (2025): Nusantara Hasana Journal, December 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i7.1882

Abstract

Nutritional problems remain a major challenge in community health development, particularly in rural areas. The Indonesian government has introduced the “Isi Piringku” concept as a visual guideline for balanced nutrition; however, its implementation requires more innovative educational approaches. This community service activity aimed to improve knowledge and awareness of balanced nutrition through technology-based “Isi Piringku” education as an effort to prevent nutritional problems in Nagari Padang Gantiang. The community service program was conducted in Nagari Padang Gantiang, Sangir Jujuan District, South Solok Regency, over a 21-day period. Participants included housewives, posyandu cadres, elementary school teachers, and village officials. Educational methods involved technology-based counseling using educational videos, interactive discussions, and question-and-answer sessions. The program resulted in improved participants’ understanding of the “Isi Piringku” concept, particularly the application of the 3J principles (timing, quantity, and type of food) in complementary feeding practices. Educational videos effectively facilitated comprehension of balanced nutrition messages. In addition, the activity fostered community commitment to developing a nutrition-aware village program through the establishment of a healthy garden to support complementary feeding practices. Technology-based “Isi Piringku” education is effective in enhancing community nutrition knowledge and awareness. The integration of digital media and participatory community activities can support stunting prevention efforts and promote the development of a healthy and nutrition-conscious village
KADAR KATEKIN DAN AKTIVITAS ANTIOKSIDAN GAMBIR (UNCARIA GAMBIR ROXB.) DI INDONESIA: TINJAUAN LITERATUR 10 TAHUN TERAKHIR (2015-2025) Vani, Ade Teti; Irwan Triansyah; Nadia Purnama Dewi; Dessy Abdullah; Aryaldy Zulkarnaini
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1862

Abstract

Indonesia is the world’s largest producer of gambier (Uncaria gambir Roxb.), which is rich in catechin, a major bioactive compound with strong antioxidant activity. Variations in catechin content and antioxidant activity of Indonesian gambier are influenced by geographical origin, plant characteristics, and processing and extraction methods. This study aims to comprehensively review the catechin content and antioxidant activity of Indonesian gambier based on scientific publications from the last decade (2015–2025). A narrative literature review method was applied by collecting relevant articles from Google Scholar, ScienceDirect, PubMed, and Garuda databases. Selected studies were original research articles reporting quantitative data on catechin levels and/or antioxidant activity of gambier originating from Indonesia. The results indicate that Indonesian gambier, particularly from West Sumatra, exhibits high catechin content and strong antioxidant activity, although considerable variation exists among regions and extraction techniques. Advanced extraction and purification methods, including solvent optimization and ultrasonic-assisted extraction, were shown to enhance catechin concentration and antioxidant capacity. Indonesian gambier has significant potential as a natural antioxidant source, highlighting the need for quality standardization and further development of processing technologies to support value-added utilization and downstream product development.