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Hubungan Faktor Risiko Aloimunisasi dengan Kejadian Inkompatibilitas Crossmatch Pada Pasien Keganasan Darah Dewasa yang Ditransfusi Packed Red Cell Berulang di RSUP Dr M Djamil Padang Herinda, Dwi Putri; Rofinda, Zelly Dia; Elvira, Dwitya; Rikarni, Rikarni; Aprilia, Dinda
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 1 (2024): Maret 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i1.1132

Abstract

Latar Belakang: Pasien keganasan darah yang mendapatkan transfusi packed red cell (PRC) berulang akan menyebabkan pembentukan aloantibodi yang dapat terdeteksi pada pemeriksaan crossmatch dan mempersulit proses transfusi selanjutnya. Objektif: Penelitian ini bertujuan untuk mengetahui hubungan antara usia, jenis kelamin, jenis keganasan, dan jumlah unit transfusi dengan kejadian inkompatibilitas crossmatch. Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain cross- sectional. Terdapat 50 sampel yang didapatkan dari rekam medis dan laboratorium. Penelitian ini menggunakan analisis univariat dan analisis bivariat. Hasil: Hasil penelitian ini menunjukan prevalensi inkompatibilitas crossmatch sebesar 16% dengan keseluruhan inkompatibilitas minor. Kejadian terbanyak didapatkan pada usia <60 tahun, perempuan, LMA dan transfusi > 10. Hasil uji statistik menunjukan tidak adanya hubungan yang signifikan antara faktor usia (p= 0,322), jenis kelamin (p= 0,050), jenis keganasan darah (p= 0,662), dan jumlah unit transfusi (p= 0,702) dengan kejadian hasil pemeriksaan crossmatch. Kesimpulan: Faktor risiko seperti usia, jenis kelamin, jenis keganasan, dan jumlah unit transfusi tidak mempunyai hubungan signifikan dengan kejadian inkompatibilitas crossmatch pada pasien keganasan darah yang mendapatkan transfusi PRC berulang
The Use of Animated Videos in Preventing Anemia in Adolescent Girls Julianawati, Tinta; Yana, Lusi; Aprilia, Dinda
Society : Jurnal Pengabdian Masyarakat Vol. 4 No. 4 (2025): Juli
Publisher : Edumedia Solution

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55824/jpm.v4i4.584

Abstract

Anemia is a serious public health problem and has an impact on the life cycle of adolescents, especially adolescent girls. Adolescent girls who suffer from anemia have limitations in the growth process, learning capacity, ability to focus on daily activities, are susceptible to infection, have a tendency to drop out of school, physical fitness levels, and work productivity. The risk of anemia in adolescent girls tends to increase with age and coincides with the teenage years when the growth process occurs most rapidly. The ages between 12 and 15 years, when nutritional needs are very high, are known to have a very high risk of suffering from anemia. One of the educational media that can be easily understood by adolescents is animated videos. The purpose of this community service is to increase knowledge about preventing anemia in adolescents. The activities carried out are in the form of education, using educational videos to prevent anemia in adolescents. The method used is socialization and health education to adolescent girls through videos and explanations of the consumption of iron tablets distributed to all adolescent girls. The location of the activity was carried out at SDN 001 Nongsa. The stages of the activity include the stages of preparation, implementation and reporting. Data from the results of community service activities showed an increase in the capacity of adolescent girls, showing a change of 22 points in the pre-post test education, HB level examination from 30 people. The examined adolescent girls who experienced anemia were 16 people (53%) and 14 people did not experience anemia. All adolescents showed high enthusiasm for this activity and hoped that anemia and nutritional status education activities could be carried out sustainably to improve the fitness and health of adolescent girls.
Diabetic Ketoacidosis in Type 1 Diabetes Mellitus Nurhakim, Lukman; Afriant, Rudy; Aprilia, Dinda
Sumatera Medical Journal Vol. 7 No. 1 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i1.11837

Abstract

Background: Diabetic ketoacidosis (DKA) is a state of metabolic decompensation/disorder characterized by the triad of hyperglycemia, acidosis and ketosis, caused by absolute or relative insulin deficiency and increased counter-regulatory hormones. Objective: To report a case of diabetic ketoacidosis (DKA) in a young adult patient with type 1 diabetes mellitus and scalp abscess, emphasizing the importance of early diagnosis and prompt management to achieve clinical improvement. Methods: This case report describes the clinical presentation, diagnostic approach, and therapeutic management of a 19-year-old male with DKA. Results: A 19-year-old male treated in the internal medicine ward of Dr. M djamil Padang with diabetic ketoacidosis, type 1 DM, and Abscess capitis. The patient was treated with rehydration and intravenous insulin infusion can show clinical improvement. Conclusion: The diagnosis in patients is based on anamnesis, physical examination and supporting examinations. Immediate therapy is needed in the management of DKA in patients. After DKA is resolved, look for the causes of the risk of DKA. On the third day of treatment the patient's condition improved clinically and the laboratory.
Peran Objek Wisata Lumpur Lapindo Sidoarjo dalam Meningkatkan Pendapatan Masyarakat Noviandari, Indah; Balafif, Mohammad; Aprilia, Dinda
Cakrawala Vol. 15 No. 1: Juni 2021
Publisher : Badan Riset dan Inovasi Daerah Provinsi Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32781/cakrawala.v15i1.368

Abstract

Kabupaten Sidoarjo mempunyai salah satu tempat wisata yang strategis dan potensial untuk dikelola, dikembangkan dan dipasarkan. Objek dalam rekreasi berupa wisata Lumpur Lapindo adalah salah satu potensi wisata terbaru yang ada di Sidoarjo. Meski awalnya berupa bencana alam yang menimpa warga Sidoarjo. Wisata lumpur lapindo ini tidak dikelola oleh pemerintah atau dinas yang terkait, namun wisata tersebut dikelola oleh paguyuban warga korban lumpur lapindo yang mata pencaharian yang lama sudah terhenti akibat luapan lumpur lapindo. Tujuan yang hendak dicapai oleh peneliti dalam penelitian ini adalah mengetahui pendapatan masyarakat sebelum dan sesudah ada objek wisata lumpur lapindo, dan mengetahui peran objek wisata lumpur lapindo sidoarjo dalam meningkatkan pendapatan masyarakat. Metode penelitian yang digunakan adalah penelitian lapangan (Field Research) yang bersifat kualitatif. Penelitian ini bersifat deskriptif kualitatif, sedangkan teknik pengumpulan data yang digunakan adalah observasi,wawancara, dan studi dokumentasi.
Characteristics of Type 2 Diabetes Mellitus Patients With Diabetic Ketoacidosis: A Study in A National Referral Hospital in Indonesia Fuada, Afifah Annis; Aprilia, Dinda; Putri, Biomechy Oktomalio
Frontiers on Healthcare Research Vol. 1 No. 2 (2024)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v1.n2.p17-23.2024

Abstract

Background: Diabetic ketoacidosis (DKA) is one of the acute complication of diabetes mellitus (DM) with high mortality and morbidity rates. Research data regarding the characteristics of patients with type 2 diabetes mellitus (T2DM) with and without DKA are not yet widely available. Therefore, further research is needed to minimize the annual morbidity and mortality rate and prevent complications at the earliest possible moment. This study was carried out to determine the differences in the characteristics of T2DM patients with and without DKA in Dr. M. Djamil Central General Hospital Padang period 1st January 2018 to 31stDecember 2020. Methods: This study used a comparative analytic study with a cross-sectional approach using the medical records of T2DM patients with and without DKA in Dr. M. Djamil Central General Hospital Padang period 1st January to 31st December 2020 with total sampling. Data analysis calculated by chi-square test, unpaired T-test, and Mann-Whitney test. Results: Most of T2DM patients with DKA were aged ≥ 40 years (62.1%), female (65.5%), secondary level of education (72.4%), DM diagnosis duration was ≤ 5 years (75.9%), had infection precipitating factors (65.5%), on insulin (58.6%), Body Mass Index (BMI) in overweight-obese criteria (55%), fasting blood glucose (FBG) < 250 mg/dl (62.1%), and post-prandial glucose (PPG) 250-600 mg/dl (51.7%). This study found that the association of age, DM diagnosis duration, precipitating factors, medication use, and PPG with DKA in T2DM patients (p<0.05). Conclusion: This study confirmed significant differences in age, DM diagnosis duration, precipitation factors, type of antidiabetic therapy, and PPG between T2DM patients with and without DKA in Dr. M. Djamil Central General Hospital Padang.
Klasifikasi Status Kemiskinan Rumah Tangga Berdasarkan Karakteristik Demografi dan Hunian Menggunakan Algoritma Clasification and Regression Tree Winata, Aji Pandu; Aprilia, Dinda; Sriliana, Idhia; Aryati, Fitri; Puspasari, Reny
Euler : Jurnal Ilmiah Matematika, Sains dan Teknologi Volume 13 Issue 3 December 2025
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/euler.v13i3.34952

Abstract

Poverty is a multidimensional issue that remains a central focus of development in Bengkulu Province. Decision-tree–based approaches, particularly the Classification and Regression Tree (CART), can be used to classify households based on demographic and housing characteristics. This study utilizes data from the 2024 National Socio-Economic Survey (SUSENAS), with household poverty status as the response variable and six predictor variables including area type, gender of household head, age of household head, number of household members, floor area of the house, and housing ownership status. The analysis consists of data preprocessing, descriptive statistics, data splitting, CART model construction, identification of influential variables, and model evaluation using a confusion matrix. The results show that the number of household members, floor area of the house, and age of the household head are the most influential variables in distinguishing poor and non-poor households. Model evaluation produced an accuracy of 0.73, sensitivity of 0.58, and specificity of 0.75. The accuracy and specificity values indicate adequate classification performance, while the low sensitivity suggests that the model is still less optimal in detecting poor households, partly due to class imbalance in the dataset. These findings indicate that the CART method can be applied to poverty analysis in Bengkulu Province, although further model improvement is needed to enhance its capability in identifying poor households.
Profil Risiko Diabetes dan Sindrom Metabolik Berdasarkan Indeks Massa Tubuh dan Glukosa Darah Sewaktu di Bukik Batabuah Aprilia, Dinda; Eva Decroli; Kam, Alexander; Efendi, Yanne Pradwi; Namanda Putri, Athari Fadhila
Abdika Sciena Vol 3 No 2 (2025): JURABDIKES Volume 3 No 2, Desember 2025
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/jurabdikes.v3i2.328

Abstract

Latar Belakang: Diabetes melitus (DM) dan sindrom metabolik merupakan masalah kesehatan global dengan peningkatan prevalensi setiap tahun. Indeks massa tubuh (IMT) dan kadar glukosa darah merupakan indikator penting dalam menilai risiko DM dan sindrom metabolik pada populasi komunitas. Tujuan: Mengetahui karakteristik indikator risiko DM dan sindrom metabolik berdasarkan IMT, GDS dan demografis masyarakat Bukik Batabuah tahun 2024. Metode: Penelitian deskriptif observasional terhadap 69 responden. Data yang dikumpulkan meliputi usia, jenis kelamin, IMT, kategori IMT, dan GDS. Analisis dilakukan secara deskriptif. Hasil: Rerata usia responden 50,93 tahun, dengan mayoritas perempuan (76,81%). Rerata IMT 23,23 kg/m² dengan 24,64% responden tergolong overweight–obesitas. Rerata GDS 130,59 mg/dL dengan nilai maksimum 337 mg/dL menunjukkan adanya risiko gangguan glukosa. Kesimpulan: Populasi Bukik Batabuah menunjukkan risiko metabolik yang ditandai dengan IMT di atas normal. Skrining komunitas dan intervensi promotif-preventif diperlukan  
Pengabdian Kepada Masyarakat Tentang Peluang Bisnis Pembudidayaan Hidroponik Aprilia, Dinda
TRIDAYA: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 1 (2024): TRIDAYA
Publisher : Prodi Akuntansi, Universitas Pamulang Kampus Serang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32493/tridaya.v1i1.37266

Abstract

Latar belakang dari kegiatan ini yaitu mencoba memperkenalkan kepada siswa mengenai sistem pembudidayaan hidroponik. Metode hidroponik sebagai alternatif dalam produk pertaniaan dipilih karena suatu metode bercocok tanam tanpa mengunakan media tanah, melainkan dengan larutan mmineral bernutrisi atau bahan lainnya. Hidroponik merupakan metode yang dapat dikembangkan dan diaplikasikan disektor rumah tangga. Tujuan yang ingin dicapai yaitu untuk menurangi sampah sampah atau pun limbah rumah tangga. Serta mengajak siswa dalam berpartisipasi menjaga lingkungannya dengan memanfaatkan lahan yang sempit dan tidak terpakai. Metode yang digunakan yaitu metode penanaman hidroponik berbasis semi organik karena tidak menguanakan bahan kimia dalam memberi nutrisi tanaman. Hasil dari pengembangan dari metode ini diharapkan siswa dapat lebih memahami sistem pembudidayaan hidroponik dan dapat mengembangkannya secara mandiri serta memanfaatkan sampah sampah bekas dan limbah rumah tanggah sehingga dapat mengurangi masalah pencemaran lingkungan. Kata kunci: Organik : Bahan yang terbuat dari alam
Glucocorticoid-induced adrenal insufficiency after receiving intravenous methylprednisolone for Graves' ophthalmopathy: a case report Pradwi Efendi, Yanne; Aprilia, Dinda; Decroli, Eva
Universa Medicina Vol. 45 No. 1 (2026): Aheaf Of Print
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2026.v45.%p

Abstract

BACKGROUNDGraves’ ophthalmopathy (GO) is the most common extrathyroidal manifestation of Graves’ disease and can significantly impair visual function and quality of life. High-dose intravenous methylprednisolone (IVMP) is recommended as first-line therapy for moderate-to-severe active GO due to its superior efficacy and tolerability compared with oral glucocorticoids. However, IVMP therapy may be associated with rare but potentially serious adverse effects, including suppression of the hypothalamic–pituitary–adrenal (HPA) axis leading to GI adrenal insufficiency (GI-AI). Case descriptionWe report the case of a 38-year-old man with Graves’ disease who developed AI following IVMP therapy for moderate-to-severe GO. The patient received five weekly doses of IVMP 500 mg (cumulative dose 2.5 g) for progressive ocular symptoms. He subsequently presented with fatigue, weight gain, moon face, and buffalo hump. Laboratory evaluation revealed a markedly low morning serum cortisol level of 1 mcg/dL, confirming adrenal insufficiency. Patient was diagnosed with GI-AI accompanied by features of iatrogenic Cushing’s syndrome. Management consisted of hydrocortisone replacement therapy at a dose of 20 mg/day along with ongoing antithyroid treatment using methimazole. Serial monitoring of cortisol levels demonstrated gradual recovery of HPA axis function, accompanied by clinical improvement. ConclusionThis case highlights that glucocorticoid-induced adrenal insufficiency can occur on IVMP used for GO. Clinicians should maintain a high index of suspicion and perform appropriate adrenal function monitoring during and after IVMP therapy to ensure early detection and safe management of this potentially life-threatening complication.