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Journal : Jurnal Bios Logos

Phytochemical Compounds and Antibacterial Test of Theonella cylindrica against Staphylococcus aureus and Escherichia coli Mambo, Christi D.; Warouw, Finny; Nangoy, Edward; Rumengan, Inneke; Kepel, Billy; Bara, Robert
JURNAL BIOS LOGOS Vol. 15 No. 2 (2025): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v15i2.59230

Abstract

Infectious diseases are a health problem faced by developing countries like Indonesia. This disease is caused by bacteria that attack humans. Improper use of antibiotics can cause bacterial resistance to antimicrobials. Antimicrobial resistance is the most significant public health threat, resulting in greater demand for finding new effective antimicrobials from natural products such as sea sponges. This research aimed to test the antibacterial activity of Theonella extract against Staphylococcus aureus and Escherichia coli and determine the class of chemical compounds contained therein. Research stages include sampling, sample preparation and extraction, qualitative phytochemical screening, making solutions, media creation, and antibacterial testing. The research showed that sponges metabolite compounds consisted of alkaloids, flavonoids, tannins, saponins, and phenolics. The diameter of the inhibition zone at concentrations of 80% and 100% showed potential antibacterial activity but more strongly inhibited the growth of Staphylococcus aureus bacteria than Escherichia coli bacteria.
Co-Authors Adinata, Daniel N. Akili, Rahayu H, Andika Surya Atmadja Anes, Brenda Militsia Christi Rosalina Angelina Stevany Regina Masengi Anthonius Kurniadi Assa, Winly Yuliana Billy Kepel Birang, Meirani F. Budi Ratag, Budi Budi Setiawan Chesya P.R. Salindeho Christoffel M. Memah Corry N. Mahama Daniel Febrian Sengkey Deeng, Gracia V. Y. Desy . Doda, Diana V.D. Edward Nangoy, Edward Frans Wantania Gampu, Agrisia Garusu, Ratna Santika Hartoyo, Vinson Harvani Boky, Harvani Herlyani Khosama Hugo Dwiputra Inneke F. M Rumengan Jehosua, Seilly Yunita Jimmy Posangi Jootje M.L Umboh Junita Maja P.S Junita Maja Pertiwi Kamae, Sitti Ramlia Kawatu, Paul A.T Kumayas, Putri Elshadai Labagow, Elisa Lantang, Christina Lapian, Albertus Theo Laura Wulandary Kaeng Lengkong, Erlika Lihu, Tutin R. M.L, Jootje Maddusa, Sri Seprianto Maja Pertiwi, Junita Mamahit, Juliet Merry Eva Mambo, Christi D. Mambo, Christi Diana Manabung, Apriliani R. Maranatha, Armando Vengo Subito Lewi Marthen Theogives Lasut, Marthen Theogives Melke J. Tumboimbela Mieke A. H. N. Kembuan Mieke A.H.N Kembuan Momole, Ansye Grace Nancy Mutiara Toreh Nike Gledis Monintja Oddi R Pinontoan Odi Pinontoan Odi Roni Pinontoan Paendong, Winner Hiskia George Paul A.T. Kawatu Pertiwi, Junita M. Pertiwi, Junita Maja Pua, Yohanes A. Purbawijaya, Poek Denny Rahayu H. Akili, Rahayu H. Ratumbanua, Fralen Julio Rianna J Sumampouw Ribka L. Wowor, Ribka L. Ricky C. Sondakh Rizal Tumewah Robert A. Bara Sekplin A. S. Sekeon, Sekplin A. S. Sengkey, Aprilia Sengkey, Omega Prisilia Silalahi, Elsa D. Soeratinoyo, Dewi K. Sugiarto, Natanael E. Sumigar, Cindy Keren Suoth, Lery F. Tangkudung, Gilbert Tewuh, Syeri Oktaviani Theresia Runtuwene Togelang, Mega Rossita Umboh, Jootje Marthen Luther Umboh, Jotje M.L Vriska V. Rambing Walewangko, Sarah Alni Wariki, Windy M. V. Wello, Novita L. L. Wiradarma, Elbert Woodford B. S. Joseph Woodford B.S. Joseph, Woodford B.S. Yantu, Sintia Salmawati Yoesdyanto, Kennytha Yonathan Andrian Yulianty Sanggelorang